Pekka Rapeli

Summary

Affiliation: Helsinki University Central Hospital
Country: Finland

Publications

  1. pmc Memory function in opioid-dependent patients treated with methadone or buprenorphine along with benzodiazepine: longitudinal change in comparison to healthy individuals
    Pekka Rapeli
    Unit for Drug Dependence, Department of Psychiatry, Helsinki University Central Hospital, Helsinki, Finland
    Subst Abuse Treat Prev Policy 4:6. 2009
  2. pmc Do drug treatment variables predict cognitive performance in multidrug-treated opioid-dependent patients? A regression analysis study
    Pekka Rapeli
    Unit for Drug Dependence, Department of Psychiatry, Helsinki University Central Hospital, Helsinki, Finland
    Subst Abuse Treat Prev Policy 7:45. 2012
  3. ncbi request reprint Do individuals with former amphetamine dependence have cognitive deficits?
    Pekka Rapeli
    Psychiatric Unit for Drug Dependence, Helsinki University Central Hospital, HUS, Finland
    Nord J Psychiatry 59:293-7. 2005
  4. pmc Cognitive functioning in opioid-dependent patients treated with buprenorphine, methadone, and other psychoactive medications: stability and correlates
    Pekka Rapeli
    Department of Psychiatry, Helsinki University Central Hospital, Finland
    BMC Clin Pharmacol 11:13. 2011
  5. pmc Methadone vs. buprenorphine/naloxone during early opioid substitution treatment: a naturalistic comparison of cognitive performance relative to healthy controls
    Pekka Rapeli
    Unit for Drug Dependence, Department of Psychiatry, Helsinki University Central Hospital, Helsinki, Finland
    BMC Clin Pharmacol 7:5. 2007
  6. pmc Cognitive function during early abstinence from opioid dependence: a comparison to age, gender, and verbal intelligence matched controls
    Pekka Rapeli
    Psychiatric Unit for Drug Dependence, Department of Psychiatry, Helsinki University Central Hospital, Finland
    BMC Psychiatry 6:9. 2006
  7. ncbi request reprint Impaired pre-attentive auditory processing in opioid dependence with and without benzodiazepine co-dependence revealed by combined magnetoencephalography and electroencephalography
    Reetta Kivisaari
    Medical Imaging Centre, Box 281, Helsinki University Central Hospital, 00029 HUS, Finland
    Prog Neuropsychopharmacol Biol Psychiatry 31:1378-86. 2007
  8. ncbi request reprint Cerebral measurements and their correlation with the onset age and the duration of opioid abuse
    Reetta Kivisaari
    Medical Imaging Center, Helsinki University Central Hospital, Helsinki, Finland
    J Opioid Manag 6:423-9. 2010
  9. ncbi request reprint Magnetic resonance imaging of severe, long-term, opiate-abuse patients without neurologic symptoms may show enlarged cerebrospinal spaces but no signs of brain pathology of vascular origin
    Reetta Kivisaari
    Helsinki Medical Imaging Center, Helsinki University Central Hospital, Helsinki, Finland
    Arch Med Res 35:395-400. 2004

Collaborators

Detail Information

Publications9

  1. pmc Memory function in opioid-dependent patients treated with methadone or buprenorphine along with benzodiazepine: longitudinal change in comparison to healthy individuals
    Pekka Rapeli
    Unit for Drug Dependence, Department of Psychiatry, Helsinki University Central Hospital, Helsinki, Finland
    Subst Abuse Treat Prev Policy 4:6. 2009
    ..The present study is the first to examine longitudinal stability of memory function in OST patients with BZD use, thus providing a new tool for health policy authorities in evaluating the usefulness of OST...
  2. pmc Do drug treatment variables predict cognitive performance in multidrug-treated opioid-dependent patients? A regression analysis study
    Pekka Rapeli
    Unit for Drug Dependence, Department of Psychiatry, Helsinki University Central Hospital, Helsinki, Finland
    Subst Abuse Treat Prev Policy 7:45. 2012
    ..Therefore, we examined whether the cognitive performance of patients in opioid-substitution treatment (OST) is associated with their drug treatment variables...
  3. ncbi request reprint Do individuals with former amphetamine dependence have cognitive deficits?
    Pekka Rapeli
    Psychiatric Unit for Drug Dependence, Helsinki University Central Hospital, HUS, Finland
    Nord J Psychiatry 59:293-7. 2005
    ..Thus, if widespread cognitive deficits are found in individuals with former amphetamine dependence, etiologies other than amphetamine abuse as such should be carefully investigated...
  4. pmc Cognitive functioning in opioid-dependent patients treated with buprenorphine, methadone, and other psychoactive medications: stability and correlates
    Pekka Rapeli
    Department of Psychiatry, Helsinki University Central Hospital, Finland
    BMC Clin Pharmacol 11:13. 2011
    ..methadone-treated patients...
  5. pmc Methadone vs. buprenorphine/naloxone during early opioid substitution treatment: a naturalistic comparison of cognitive performance relative to healthy controls
    Pekka Rapeli
    Unit for Drug Dependence, Department of Psychiatry, Helsinki University Central Hospital, Helsinki, Finland
    BMC Clin Pharmacol 7:5. 2007
    ..Therefore, we investigated attention, working memory, and verbal memory of opioid-dependent patients within six weeks after the introduction of OST in a naturalistic setting and compared to those of healthy controls...
  6. pmc Cognitive function during early abstinence from opioid dependence: a comparison to age, gender, and verbal intelligence matched controls
    Pekka Rapeli
    Psychiatric Unit for Drug Dependence, Department of Psychiatry, Helsinki University Central Hospital, Finland
    BMC Psychiatry 6:9. 2006
    ..It was hypothesized that cognitive deficits are pronounced immediately after peak withdrawal symptoms have passed and then partially recover...
  7. ncbi request reprint Impaired pre-attentive auditory processing in opioid dependence with and without benzodiazepine co-dependence revealed by combined magnetoencephalography and electroencephalography
    Reetta Kivisaari
    Medical Imaging Centre, Box 281, Helsinki University Central Hospital, 00029 HUS, Finland
    Prog Neuropsychopharmacol Biol Psychiatry 31:1378-86. 2007
    ..There were no group differences in EEG amplitude measures. In conclusion, our results suggest delayed pre-attentive auditory processing of novel information in opioid dependence. Benzodiazepine co-dependence modulated N1m response...
  8. ncbi request reprint Cerebral measurements and their correlation with the onset age and the duration of opioid abuse
    Reetta Kivisaari
    Medical Imaging Center, Helsinki University Central Hospital, Helsinki, Finland
    J Opioid Manag 6:423-9. 2010
    ..Opioid-dependent patients have been shown to have structural brain alterations. This study focuses on magnetic resonance imaging (MRI) measurements of brain and their correlation with the onset age and the duration of opioid abuse...
  9. ncbi request reprint Magnetic resonance imaging of severe, long-term, opiate-abuse patients without neurologic symptoms may show enlarged cerebrospinal spaces but no signs of brain pathology of vascular origin
    Reetta Kivisaari
    Helsinki Medical Imaging Center, Helsinki University Central Hospital, Helsinki, Finland
    Arch Med Res 35:395-400. 2004
    ..In contrast, their minor effects on brain structures are not well established. We evaluated brain magnetic resonance images (MRI) of opiate-dependent subjects who had no major neurologic symptoms or psychiatric disorder...