V Pentikäinen

Summary

Affiliation: Helsinki University Central Hospital
Country: Finland

Publications

  1. ncbi request reprint Estradiol acts as a germ cell survival factor in the human testis in vitro
    V Pentikäinen
    Hospital for Children and Adolescents, University of Helsinki, Finland
    J Clin Endocrinol Metab 85:2057-67. 2000
  2. ncbi request reprint TNFalpha down-regulates the Fas ligand and inhibits germ cell apoptosis in the human testis
    V Pentikäinen
    Program for Developmental and Reproductive Biology, Biomedicum Helsinki, and Hospital for Children and Adolescents, University of Helsinki, FIN 00290 Helsinki, Finland
    J Clin Endocrinol Metab 86:4480-8. 2001
  3. ncbi request reprint Cell death and its suppression in human ovarian tissue culture
    M Otala
    Programme for Developmental and Reproductive Biology, Biomedicum Helsinki, and Hospital for Children and Adolescents, University of Helsinki, FIN 00290, Finland
    Mol Hum Reprod 8:228-36. 2002
  4. ncbi request reprint Partial oxygen pressure and mitochondrial permeability transition affect germ cell apoptosis in the human testis
    K Erkkila
    Hospital for Children and Adolescents, University of Helsinki, Finland
    J Clin Endocrinol Metab 84:4253-9. 1999
  5. ncbi request reprint Lactate inhibits germ cell apoptosis in the human testis
    K Erkkila
    Programme for Developmental and Reproductive Biology, Biomedicum Helsinki, Hospital for Children and Adolescents, University of Helsinki, Helsinki, Finland
    Mol Hum Reprod 8:109-17. 2002
  6. ncbi request reprint Fas regulates germ cell apoptosis in the human testis in vitro
    V Pentikäinen
    Hospital for Children and Adolescents, University of Helsinki, FIN 00029 Helsinki, Finland
    Am J Physiol 276:E310-6. 1999
  7. ncbi request reprint Expression of transcription factor GATA-4 during human testicular development and disease
    I Ketola
    Children s Hospital, University of Helsinki, Finland
    J Clin Endocrinol Metab 85:3925-31. 2000

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Estradiol acts as a germ cell survival factor in the human testis in vitro
    V Pentikäinen
    Hospital for Children and Adolescents, University of Helsinki, Finland
    J Clin Endocrinol Metab 85:2057-67. 2000
    ..The novel findings of the present study together with the previously reported indirect effects of estrogens on male germ cells indicate the importance of estrogens for the normal function of the testis...
  2. ncbi request reprint TNFalpha down-regulates the Fas ligand and inhibits germ cell apoptosis in the human testis
    V Pentikäinen
    Program for Developmental and Reproductive Biology, Biomedicum Helsinki, and Hospital for Children and Adolescents, University of Helsinki, FIN 00290 Helsinki, Finland
    J Clin Endocrinol Metab 86:4480-8. 2001
    ..Thus, in the seminiferous tubules, germ cell-derived TNFalpha may regulate the level of the Fas ligand and thereby control physiological germ cell apoptosis...
  3. ncbi request reprint Cell death and its suppression in human ovarian tissue culture
    M Otala
    Programme for Developmental and Reproductive Biology, Biomedicum Helsinki, and Hospital for Children and Adolescents, University of Helsinki, FIN 00290, Finland
    Mol Hum Reprod 8:228-36. 2002
    ..The present tissue culture model can be used for identifying components capable of inhibiting cell death in vitro...
  4. ncbi request reprint Partial oxygen pressure and mitochondrial permeability transition affect germ cell apoptosis in the human testis
    K Erkkila
    Hospital for Children and Adolescents, University of Helsinki, Finland
    J Clin Endocrinol Metab 84:4253-9. 1999
    ..The present results imply that to improve germ cell viability in in vitro fertilization techniques, the partial oxygen pressure should be lowered...
  5. ncbi request reprint Lactate inhibits germ cell apoptosis in the human testis
    K Erkkila
    Programme for Developmental and Reproductive Biology, Biomedicum Helsinki, Hospital for Children and Adolescents, University of Helsinki, Helsinki, Finland
    Mol Hum Reprod 8:109-17. 2002
    ..In conclusion, testicular cell death was effectively regulated by lactate, which may be regarded as a potential compound for optimizing in-vitro methods involving male germ cells for assisted reproduction...
  6. ncbi request reprint Fas regulates germ cell apoptosis in the human testis in vitro
    V Pentikäinen
    Hospital for Children and Adolescents, University of Helsinki, FIN 00029 Helsinki, Finland
    Am J Physiol 276:E310-6. 1999
    ..The present results suggest an important role for the Fas-FasL system in the regulation of germ cell apoptosis in the human testis...
  7. ncbi request reprint Expression of transcription factor GATA-4 during human testicular development and disease
    I Ketola
    Children s Hospital, University of Helsinki, Finland
    J Clin Endocrinol Metab 85:3925-31. 2000
    ..GATA-4 protein is abundantly present in Sertoli and Leydig cell tumors, suggesting a relationship to tumorigenesis or tumor progression in somatic cell-derived testicular neoplasms...