Research Topics
| Eero PekkonenSummaryAffiliation: Helsinki University Central Hospital Country: Finland Publications
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Detail Information
Publications
Magnetoencephalographic evidence of abnormal auditory processing in amyotrophic lateral sclerosis with bulbar signsEero Pekkonen
Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland
Clin Neurophysiol 115:309-15. 2004..Besides motor neuron damage, conscious auditory processing appears to be impaired in ALS, whereas it has remained ambiguous whether preceding automatic auditory processing is abnormal in ALS and specifically in ALS with bulbar signs...
Impaired temporal lobe processing of preattentive auditory discrimination in schizophreniaEero Pekkonen
Department of Neurology, University of Helsinki, Finland
Schizophr Bull 28:467-74. 2002..These results suggest that patients with schizophrenia have impaired auditory processing in the temporal lobes underlying preattentive stimulus discrimination that is also selectively delayed in the left hemisphere...
Delayed auditory processing underlying stimulus detection in Down syndromeEero Pekkonen
Department of Neurology, University of Helsinki, Finland
Neuroimage 35:1547-50. 2007..Given that anticholinergic drugs modulate AEFs, degeneration of cholinergic system in DS could contribute to the damaged auditory processing...
Effects of scopolamine on MEG spectral power and coherence in elderly subjectsDaria Osipova
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, P O Box 9 00014, Helsinki, Finland
Clin Neurophysiol 114:1902-7. 2003..In order to test the sensitivity of spectral power and hemispheric coherence to changes in cholinergic transmission, we evaluated quantitative magnetoencephalogram (MEG) after intravenous injection of scopolamine...
Cholinergic modulation of preattentive auditory processing in agingEero Pekkonen
Department of Neurology, University of Helsinki, PO Box 340, FIN 00029 HUS, Finland
Neuroimage 27:387-92. 2005..The combined MEG/EEG measurements using particularly auditory N100 response might offer an objective tool to monitor cholinergic activity in aging and Alzheimer's disease (AD)...
Dopamine modulates involuntary attention shifting and reorienting: an electromagnetic studySeppo Kahkonen
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Helsinki, Finland
Clin Neurophysiol 113:1894-902. 2002..Dopaminergic function has been closely associated with attentional performance, but its precise role has remained elusive...
Enhanced magnetic auditory steady-state response in early Alzheimer's diseaseDaria Osipova
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Finland
Clin Neurophysiol 117:1990-5. 2006..We studied the auditory steady-state response (SSR) which represents the net effect of entrained background activity and superimposed cortical evoked responses, in AD patients and healthy controls...
Source estimation of spontaneous MEG oscillations in mild cognitive impairmentDaria Osipova
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Helsinki, Finland
Neurosci Lett 405:57-61. 2006..Deficits in the distribution of oscillatory sources in the resting state are thus likely to occur at later stages of cognitive impairment than MCI...
Modulation of somatosensory evoked fields from SI and SII by acute GABA A-agonism and paired-pulse stimulationJuha Huttunen
BioMag Laboratory, Engineering Centre, University of Helsinki, Helsinki, Finland
Neuroimage 40:427-34. 2008..The lack of PPD modulation of N20m by lorazepam suggests that paired-pulse depression of the first cortical excitatory response (N20m) may be caused by mechanisms other than GABA A receptor-mediated inhibition...
Altered generation of spontaneous oscillations in Alzheimer's diseaseDaria Osipova
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Finland
Neuroimage 27:835-41. 2005....
Auditory discrimination after left-hemisphere stroke: a mismatch negativity follow-up studyTitta-Maria Ilvonen
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Finland
Stroke 34:1746-51. 2003..CONCLUSIONS: These results suggest that the MMN can be used as an index of the recovery of auditory discrimination...
Aging and cholinergic modulation of the transient magnetic 40-Hz auditory responseJyrki Ahveninen
Cognitive Brain Research Unit, Department of Neurology, University of Helsinki, FIN 00014 Helsinki, Finland
Neuroimage 15:153-8. 2002..In sum, the transient magnetic 40-Hz auditory response may be useful in studies on brain cholinergic deficits in elderly subjects...
Somatomotor mu rhythm amplitude correlates with rigidity during deep brain stimulation in Parkinsonian patientsKatja Airaksinen
BioMag Laboratory, HUSLAB, Helsinki University Central Hospital, Helsinki, Finland
Clin Neurophysiol 123:2010-7. 2012..We studied whether cortical spontaneous activity is modified by deep brain stimulation (DBS) in advanced Parkinson's disease and if the modifications are related to the clinical symptoms...
Dynamic neural activity recorded from human amygdala during fear conditioning using magnetoencephalographySandra N Moses
Department of Psychology, University of New Mexico, Albuquerque, NM 87109, USA
Brain Res Bull 71:452-60. 2007..The amygdala also shows stimulus omission-related activation that could potentially provide feedback about experienced stimulus contingencies to modify future responding during learning and extinction...
The interplay of lorazepam-induced brain oscillations: microstructural electromagnetic studyAlexander A Fingelkurts
BM Science Brain and Mind Technologies Research Centre, Espoo, Finland
Clin Neurophysiol 115:674-90. 2004....
Local and remote functional connectivity of neocortex under the inhibition influenceAndrew A Fingelkurts
BM Science Brain and Mind Technologies Research Centre, Espoo, Finland
Neuroimage 22:1390-406. 2004..It was shown that GABA signaling reorganized the dynamics of local neuronal populations and the remote functional connectivity between them...
Enhancement of GABA-related signalling is associated with increase of functional connectivity in human cortexAndrew A Fingelkurts
BM-Science Brain and Mind Technologies Research Centre, Espoo, Finland
Hum Brain Mapp 22:27-39. 2004..These results suggest that inhibition can be an efficient mechanism for synchronization of large neuronal populations...
Effects of an acute D2-dopaminergic blockade on the somatosensory cortical responses in healthy humans: evidence from evoked magnetic fieldsJuha Huttunen
BioMag Laboratory, Medical Engineering Centre Department of Clinical Neurophysiology, Helsinki University Central Hospital, P O Box 340, FIN 00029 HUS
Neuroreport 14:1609-12. 2003..05). Responses arising from SII were not significantly changed. The results suggest that dopaminergic activity may be involved in modulating somatosensory processing after the initial stages of cortical activation...
