P Osterlund

Summary

Affiliation: Helsinki University Central Hospital
Country: Finland

Publications

  1. ncbi request reprint CEA fluctuation during a single fluorouracil-based chemotherapy cycle for metastatic colorectal cancer
    Kethe Hermunen
    Department of Oncology, Helsinki University Central Hospital, P O Box 180, FIN 00029 HUS, Finland
    Anticancer Res 33:253-60. 2013
  2. ncbi request reprint A phase I study of raltitrexed (Tomudex) combined with carmofur in metastatic colorectal cancer
    P Osterlund
    Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland
    Oncology 61:113-9. 2001
  3. pmc Raltitrexed treatment promotes systemic inflammatory reaction in patients with colorectal carcinoma
    P Osterlund
    Department of Oncology, Helsinki University Central Hospital, Haartmaninkatu 4, FIN 00029 Helsinki, Finland
    Br J Cancer 87:591-9. 2002
  4. ncbi request reprint Lactose intolerance associated with adjuvant 5-fluorouracil-based chemotherapy for colorectal cancer
    Pia Osterlund
    Department of Oncology, Helsinki University Central Hospital, Finland
    Clin Gastroenterol Hepatol 2:696-703. 2004
  5. pmc Lactobacillus supplementation for diarrhoea related to chemotherapy of colorectal cancer: a randomised study
    P Osterlund
    Department of Oncology, Helsinki University Central Hospital, PO Box 180, 00029 HUS Helsinki, Finland
    Br J Cancer 97:1028-34. 2007
  6. pmc Hypertension and overall survival in metastatic colorectal cancer patients treated with bevacizumab-containing chemotherapy
    P Osterlund
    Department of Oncology, Helsinki University Central Hospital, P O Box 180, HUS Helsinki 00029, Finland
    Br J Cancer 104:599-604. 2011
  7. ncbi request reprint Surgery combined with oncological treatments in liver metastases from colorectal cancer
    H Isoniemi
    Transplantation and Liver Surgery Clinic, Helsinki University Central Hospital, Helsinki, Finland, University of Helsinki, Helsinki, Finland
    Scand J Surg 100:35-41. 2011
  8. ncbi request reprint Does preoperative radiotherapy with postoperative chemotherapy increase acute side-effects and postoperative complications of total mesorectal excision? Report of the randomized finnish rectal cancer trial
    S Salmenkylä
    Department of Surgery, Helsinki University Central Hospital, Helsinki, Finland
    Scand J Surg 101:275-82. 2012
  9. ncbi request reprint Temporal trends in the proportion cured for cancer of the colon and rectum: a population-based study using data from the Finnish Cancer Registry
    Paul C Lambert
    Department of Health Sciences, Centre for Biostatistics and Genetic Epidemiology, University of Leicester, Leicester, United Kingdom, and Department of Oncology, Helsinki University Central Hospital, Finland
    Int J Cancer 121:2052-9. 2007

Collaborators

Detail Information

Publications9

  1. ncbi request reprint CEA fluctuation during a single fluorouracil-based chemotherapy cycle for metastatic colorectal cancer
    Kethe Hermunen
    Department of Oncology, Helsinki University Central Hospital, P O Box 180, FIN 00029 HUS, Finland
    Anticancer Res 33:253-60. 2013
    ..We studied weekly CEA during one fluorouracil-based chemotherapy cycle, correlated with long-term (8-12 week interval) computed tomography (CT) and CEA responses...
  2. ncbi request reprint A phase I study of raltitrexed (Tomudex) combined with carmofur in metastatic colorectal cancer
    P Osterlund
    Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland
    Oncology 61:113-9. 2001
    ..The aim of the study was to define the maximum tolerated dose (MTD) of the combination of raltitrexed plus carmofur, and to evaluate the tolerability and efficacy of this combination in metastatic colorectal cancer...
  3. pmc Raltitrexed treatment promotes systemic inflammatory reaction in patients with colorectal carcinoma
    P Osterlund
    Department of Oncology, Helsinki University Central Hospital, Haartmaninkatu 4, FIN 00029 Helsinki, Finland
    Br J Cancer 87:591-9. 2002
    ..These findings suggest that colorectal cancer patients treated with raltitrexed may develop drug-related systemic inflammation, which may be difficult to discriminate from infection...
  4. ncbi request reprint Lactose intolerance associated with adjuvant 5-fluorouracil-based chemotherapy for colorectal cancer
    Pia Osterlund
    Department of Oncology, Helsinki University Central Hospital, Finland
    Clin Gastroenterol Hepatol 2:696-703. 2004
    ..Bowel mucosal injury associated with 5-fluorouracil (5-FU) treatment might result in secondary lactose intolerance. The frequency and clinical significance of 5-FU-related hypolactasia are unknown...
  5. pmc Lactobacillus supplementation for diarrhoea related to chemotherapy of colorectal cancer: a randomised study
    P Osterlund
    Department of Oncology, Helsinki University Central Hospital, PO Box 180, 00029 HUS Helsinki, Finland
    Br J Cancer 97:1028-34. 2007
    ..We conclude that Lactobacillus GG supplementation is well tolerated and may reduce the frequency of severe diarrhoea and abdominal discomfort related to 5-FU-based chemotherapy...
  6. pmc Hypertension and overall survival in metastatic colorectal cancer patients treated with bevacizumab-containing chemotherapy
    P Osterlund
    Department of Oncology, Helsinki University Central Hospital, P O Box 180, HUS Helsinki 00029, Finland
    Br J Cancer 104:599-604. 2011
    ..It may be a marker of VEGF signalling pathway inhibition and therefore represent a cancer biomarker in metastatic colorectal cancer (mCRC) patients treated with chemotherapy and bevacizumab...
  7. ncbi request reprint Surgery combined with oncological treatments in liver metastases from colorectal cancer
    H Isoniemi
    Transplantation and Liver Surgery Clinic, Helsinki University Central Hospital, Helsinki, Finland, University of Helsinki, Helsinki, Finland
    Scand J Surg 100:35-41. 2011
    ..Multidisciplinary management of metastatic colorectal cancer has increased the number of patients with potentially curative treatment and has improved patient survival...
  8. ncbi request reprint Does preoperative radiotherapy with postoperative chemotherapy increase acute side-effects and postoperative complications of total mesorectal excision? Report of the randomized finnish rectal cancer trial
    S Salmenkylä
    Department of Surgery, Helsinki University Central Hospital, Helsinki, Finland
    Scand J Surg 101:275-82. 2012
    ..8%). Conclusions: Perioperative adjuvant therapy was generally well tolerated and did not lead to an increase in serious surgical complications. Wound infections and perineal wound dehiscence were more common in irradiated patients...
  9. ncbi request reprint Temporal trends in the proportion cured for cancer of the colon and rectum: a population-based study using data from the Finnish Cancer Registry
    Paul C Lambert
    Department of Health Sciences, Centre for Biostatistics and Genetic Epidemiology, University of Leicester, Leicester, United Kingdom, and Department of Oncology, Helsinki University Central Hospital, Finland
    Int J Cancer 121:2052-9. 2007
    ..The reasons for these impressive increases in patient survival are complex, but are highly likely to be strongly related to many improvements in cancer care over this same time period...