Kaarina Kukkonen

Summary

Affiliation: Helsinki University Central Hospital
Country: Finland

Publications

  1. doi request reprint Long-term safety and impact on infection rates of postnatal probiotic and prebiotic (synbiotic) treatment: randomized, double-blind, placebo-controlled trial
    Kaarina Kukkonen
    Department of Pediatrics, Skin and Allergy Hospital, Helsinki University Central Hospital, Meilahdentie 2, PO Box 160, 00029 HUCH Helsinki, Finland
    Pediatrics 122:8-12. 2008
  2. doi request reprint Ovalbumin-specific immunoglobulins A and G levels at age 2 years are associated with the occurrence of atopic disorders
    A K Kukkonen
    Skin and Allergy Hospital, University of Helsinki, Helsinki, Finland
    Clin Exp Allergy 41:1414-21. 2011
  3. ncbi request reprint Effect of probiotics on vaccine antibody responses in infancy--a randomized placebo-controlled double-blind trial
    Kaarina Kukkonen
    Skin and Allergy Hospital, University of Helsinki, Helsinki, Finland
    Pediatr Allergy Immunol 17:416-21. 2006
  4. doi request reprint Airway inflammation in probiotic-treated children at 5 years
    Anna K Kukkonen
    The Skin and Allergy Hospital, University of Helsinki, Helsinki, Finland
    Pediatr Allergy Immunol 22:249-51. 2011
  5. doi request reprint High intestinal IgA associates with reduced risk of IgE-associated allergic diseases
    Kaarina Kukkonen
    The Skin and Allergy Hospital, Department of Pediatric Allergology, University of Helsinki, Helsinki, Finland
    Pediatr Allergy Immunol 21:67-73. 2010
  6. ncbi request reprint Probiotics and prebiotic galacto-oligosaccharides in the prevention of allergic diseases: a randomized, double-blind, placebo-controlled trial
    Kaarina Kukkonen
    Skin and Allergy Hospital, University of Helsinki, Finland
    J Allergy Clin Immunol 119:192-8. 2007
  7. doi request reprint Probiotics prevent IgE-associated allergy until age 5 years in cesarean-delivered children but not in the total cohort
    Mikael Kuitunen
    Skin and Allergy Hospital, Helsinki University Central Hospital, Helsinki, Finland
    J Allergy Clin Immunol 123:335-41. 2009
  8. ncbi request reprint Increased activation of GATA-3, IL-2 and IL-5 of cord blood mononuclear cells in infants with IgE sensitization
    Emma Marschan
    The Hospital for Children and Adolescents, University of Helsinki, Helsinki, Finland
    Pediatr Allergy Immunol 19:132-9. 2008
  9. doi request reprint Pro- and prebiotic supplementation induces a transient reduction in hemoglobin concentration in infants
    Mikael Kuitunen
    Skin and Allergy Hospital, Finland
    J Pediatr Gastroenterol Nutr 49:626-30. 2009
  10. pmc Probiotics in the treatment and prevention of allergy in children
    Erkki Savilahti
    From the Hospital for Children and Adolescents, Skin and Allergy Hospital, University of Helsinki, Helsinki, Finland
    World Allergy Organ J 2:69-76. 2009

Collaborators

Detail Information

Publications10

  1. doi request reprint Long-term safety and impact on infection rates of postnatal probiotic and prebiotic (synbiotic) treatment: randomized, double-blind, placebo-controlled trial
    Kaarina Kukkonen
    Department of Pediatrics, Skin and Allergy Hospital, Helsinki University Central Hospital, Meilahdentie 2, PO Box 160, 00029 HUCH Helsinki, Finland
    Pediatrics 122:8-12. 2008
    ..In a randomized, placebo-controlled, double-blind trial, we studied the safety and long-term effects of feeding synbiotics to newborn infants...
  2. doi request reprint Ovalbumin-specific immunoglobulins A and G levels at age 2 years are associated with the occurrence of atopic disorders
    A K Kukkonen
    Skin and Allergy Hospital, University of Helsinki, Helsinki, Finland
    Clin Exp Allergy 41:1414-21. 2011
    ..Humoral responses to food antigens may reflect the propensity of a child's immune system to develop tolerance to innocuous antigens. Early nutrition as well as probiotics may influence these immunological responses...
  3. ncbi request reprint Effect of probiotics on vaccine antibody responses in infancy--a randomized placebo-controlled double-blind trial
    Kaarina Kukkonen
    Skin and Allergy Hospital, University of Helsinki, Helsinki, Finland
    Pediatr Allergy Immunol 17:416-21. 2006
    ..49) vs. 0.81 (0.56-1.39) IU/ml (p = 0.310), IgG titers were comparable. In conclusion, in allergy-prone infants probiotics seem not to impair antibody responses to diphtheria, tetanus, or Hib, but may improve response to Hib immunization...
  4. doi request reprint Airway inflammation in probiotic-treated children at 5 years
    Anna K Kukkonen
    The Skin and Allergy Hospital, University of Helsinki, Helsinki, Finland
    Pediatr Allergy Immunol 22:249-51. 2011
    ..009). FE(NO) correlated positively with serum total and allergen-specific IgE concentrations. Early intervention with probiotics and pre-biotics does not affect airway inflammation later in childhood...
  5. doi request reprint High intestinal IgA associates with reduced risk of IgE-associated allergic diseases
    Kaarina Kukkonen
    The Skin and Allergy Hospital, Department of Pediatric Allergology, University of Helsinki, Helsinki, Finland
    Pediatr Allergy Immunol 21:67-73. 2010
    ..085) and significantly increased faecal alpha1-AT (p = 0.001). High intestinal IgA in early life associates with minimal intestinal inflammation and indicates reduced risk for IgE-associated allergic diseases...
  6. ncbi request reprint Probiotics and prebiotic galacto-oligosaccharides in the prevention of allergic diseases: a randomized, double-blind, placebo-controlled trial
    Kaarina Kukkonen
    Skin and Allergy Hospital, University of Helsinki, Finland
    J Allergy Clin Immunol 119:192-8. 2007
    ..The increase in allergic diseases is attributed to a relative lack of microbial stimulation of the infantile gut immune system. Probiotics, live health-promoting microbes, might offer such stimulation...
  7. doi request reprint Probiotics prevent IgE-associated allergy until age 5 years in cesarean-delivered children but not in the total cohort
    Mikael Kuitunen
    Skin and Allergy Hospital, Helsinki University Central Hospital, Helsinki, Finland
    J Allergy Clin Immunol 123:335-41. 2009
    ..Allergic children have a different fecal microflora, with less lactobacilli and bifidobacteria. Beneficial effects regarding the development of allergy have been suggested to come through probiotic supplementation...
  8. ncbi request reprint Increased activation of GATA-3, IL-2 and IL-5 of cord blood mononuclear cells in infants with IgE sensitization
    Emma Marschan
    The Hospital for Children and Adolescents, University of Helsinki, Helsinki, Finland
    Pediatr Allergy Immunol 19:132-9. 2008
    ..The immune deviation towards Th2-type immunity developed already in utero and seemed to modulate the pattern of immune response favoring an IgE response to environmental antigens...
  9. doi request reprint Pro- and prebiotic supplementation induces a transient reduction in hemoglobin concentration in infants
    Mikael Kuitunen
    Skin and Allergy Hospital, Finland
    J Pediatr Gastroenterol Nutr 49:626-30. 2009
    ..Regarding safety, we investigated the effect of prenatal probiotic and 6 months of pro- and prebiotic supplementation of infants on their hematologic values at 6 months and 2 years and factors affecting these values...
  10. pmc Probiotics in the treatment and prevention of allergy in children
    Erkki Savilahti
    From the Hospital for Children and Adolescents, Skin and Allergy Hospital, University of Helsinki, Helsinki, Finland
    World Allergy Organ J 2:69-76. 2009
    ..This may be reached by finding new strains of probiotics affecting stronger stimulation of immune system, together with longer lasting and varying treatment schedules. However, safety issues have to be observed...