Research Topics
| T ErkinjunttiSummaryAffiliation: Helsinki University Central Hospital Country: Finland Publications
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Detail Information
Publications
Insomnia in ischemic stroke patientsA Leppävuori
Department of Psychiatry, Psychiatric Consultation Unit, Helsinki University Central Hospital, Helsinki, Finland
Cerebrovasc Dis 14:90-7. 2002..Insomnia should be taken into consideration in treating and rehabilitating stroke patients...- Cognitive profile of subcortical ischaemic vascular diseaseH Jokinen
Department of Psychology, University of Helsinki, Helsinki, Finland
J Neurol Neurosurg Psychiatry 77:28-33. 2006..The aim of this study is to describe in detail the neuropsychological characteristics of patients with SIVD from a large well defined stroke cohort... - White matter hyperintensities as a predictor of neuropsychological deficits post-strokeH Jokinen
Department of Neurology, Helsinki University Central Hospital, P O Box 302, FIN 00029 HUS, Helsinki, Finland
J Neurol Neurosurg Psychiatry 76:1229-33. 2005..The purpose of this study was to explore how the severity and location of WMHs predict neuropsychological test performance in the context of other brain lesions in elderly stroke patients... - Medial temporal lobe atrophy and memory deficits in elderly stroke patientsH Jokinen
Department of Psychology, University of Helsinki, Helsinki, Finland
Eur J Neurol 11:825-32. 2004..The most vulnerable domains are memory and visuospatial functions, whereas verbal and executive functions seem to be unrelated to MTA... - Magnetic resonance imaging correlates of depression after ischemic strokeR Vataja
Department of Clinical Neurosciences, Memory Research Unit, Helsinki University Central Hospital, PO Box 300, FIN-00029 HUS, Finland
Arch Gen Psychiatry 58:925-31. 2001..3), and mean volume of infarcts in the right occipital lobe (OR, 0.98; 95% CI, 0.96-0.99). CONCLUSION: Lesions affecting the prefrontosubcortical circuits, especially on the left side, are correlates of depression after ischemic stroke... - Brain atrophy accelerates cognitive decline in cerebral small vessel disease: the LADIS studyH Jokinen
Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland
Neurology 78:1785-92. 2012..To examine the independent contributions and combined interactions of medial temporal lobe atrophy (MTA), cortical and subcortical atrophy, and white matter lesion (WML) volume in longitudinal cognitive performance... - MRI correlates of executive dysfunction in patients with ischaemic strokeR Vataja
Memory Research Unit, Department of Clinical Neurosciences, Helsinki University Central Hospital, Helsinki, Finland
Eur J Neurol 10:625-31. 2003..Brain infarcts and WML affecting the frontal-subcortical circuits or the pons may increase risk for ED in stroke patients... - MRI pontine hyperintensity after supratentorial ischemic stroke relates to poor clinical outcomeR Mäntyla
Departments of Radiology, Helsinki University Central Hospital, Helsinki, Finland
Stroke 31:695-700. 2000..We examined the frequency, as well as the radiological and clinical correlates, of PHI in poststroke patients... - Magnetic resonance imaging white matter hyperintensities and mechanism of ischemic strokeR Mäntyla
Department of Radiology, Memory Research Unit, Helsinki University Central Hospital, Finland
Stroke 30:2053-8. 1999..We sought to determine the relations between infarct subtype and white matter hyperintensities (WMHIs) on MRI... - Cognitive functions and depression as predictors of poor outcome 15 months after strokeT Pohjasvaara
Stroke Unit, Department of Clinical Neuroscience, Helsinki University Central Hospital, Helsinki, Finland
Cerebrovasc Dis 14:228-33. 2002..1, 95% CI 1.02-1.12), between 3 and 15 months follow-up, had an independent effect on dependent living 15 months after ischemic stroke. This challenges the care and rehabilitation of these items even at the stable period after stroke... - Poststroke depression and lesion location revisitedR Vataja
Department of Neurology, Memory Research Unit, Stroke Unit, Psychiatry, Psychiatric Consultation Unit, Helsinki University Central Hospital, Helsinki, Finland
J Neuropsychiatry Clin Neurosci 16:156-62. 2004..Using a logistic regression analysis, the authors found that a brain infarct that affected pallidum was a strong independent MRI correlate for poststroke depression (odds ratio = 7.2)... - Evaluation of various methods of assessing symptoms of cognitive impairment and dementiaT Pohjasvaara
Memory Research and Stroke Unit, Department of Clinical Neuroscience, Helsinki University Central Hospital, Helsinki, Finland
Alzheimer Dis Assoc Disord 15:184-93. 2001..This may have serious influences on investigation and treatment of patients. We underline the importance of further debate and studies to refine the categories of cognitive impairment used in the setting of CVD... - Impaired preconscious auditory processing and cognitive functions in Alzheimer's diseaseE Pekkonen
Department of Neurology, Helsinki University Central Hospital, Finland
Clin Neurophysiol 110:1942-7. 1999..To investigate whether auditory processing correlates with the impairment of the higher cortical functions... - Potential long-term effects of rivastigmine on disease progression may be linked to drug effects on vascular changes in Alzheimer brainsT Erkinjuntti
Department of Neurology, Helsinki University Central Hospital, HYKS, Finland
Int J Clin Pract 57:756-60. 2003..These findings may have an important influence on the way cholinesterase inhibitors are prescribed... - Galantamine treatment in Alzheimer's disease with cerebrovascular disease: responder analyses from a randomized, controlled trial (GAL-INT-6)T Erkinjuntti
Memory Research Unit, Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland
J Psychopharmacol 22:761-8. 2008..These findings are consistent with a broad range of cognitive, functional and behavioural benefits with galantamine across the spectrum of AD and AD with CVD... - Heterogeneity of cognitive profiles in aging: successful aging, normal aging, and individuals at risk for cognitive declineR Ylikoski
Neuropsychological Unit, Department of Clinical Neurosciences, P O Box 300, Helsinki University Central Hospital, Helsinki, Finland
Eur J Neurol 6:645-52. 1999..Age, activity and intellectual levels, and to a lesser degree education, were significantly related to the cluster solution. The present findings caution against treating samples of elderly individuals as homogeneous... - Poststroke dementia predicts poor survival in long-term follow-up: influence of prestroke cognitive decline and previous strokeS Melkas
Department of Neurology, Helsinki University Central Hospital, POB 300, 00029 HUS, Finland
J Neurol Neurosurg Psychiatry 80:865-70. 2009..The aim of this study was to investigate the influence of poststroke dementia on long-term survival after acute stroke and also to assess the possible influence of prestroke cognitive decline and previous stroke on this relationship... - Small-vessel disease relates to poor poststroke survival in a 12-year follow-upS Melkas
Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland
Neurology 76:734-9. 2011..We sought to compare ultra-long-term poststroke survival in small-vessel disease (SVD) vs non-SVD subtype of stroke... - Depression is an independent predictor of poor long-term functional outcome post-strokeT Pohjasvaara
Memory Research Unit, Department of Clinical Neuroscience, Helsinki University Central Hospital, Helsinki, Finland
Eur J Neurol 8:315-9. 2001..5, 95% CI 1.6-3.8). More careful examination and treatment of depression in stroke patients is emphasized... - Suicidal ideas in stroke patients 3 and 15 months after strokeT Pohjasvaara
Department of Clinical Neuroscience, Psychiatric Consultation Unit, Helsinki University Central Hospital, Helsinki, Finland
Cerebrovasc Dis 12:21-6. 2001..Recurrent strokes, depressive symptoms, more disabling stroke and right-sided stroke correlated to suicidal ideas at 15 months after stroke. Early identification of these risk factors may lead to effective therapeutic intervention... - Incident lacunes influence cognitive decline: the LADIS studyH Jokinen
Memory Research Unit, Department of Neurology, University of Helsinki, Helsinki, Finland
Neurology 76:1872-8. 2011..This study investigated whether incident lacunes on MRI determine longitudinal cognitive change in elderly subjects with WML... - Perseveration in Alzheimer's diseaseS Pekkala
Department of Speech Sciences, University of Helsinki, Helsinki, Finland
Dement Geriatr Cogn Disord 25:109-14. 2008..CONCLUSION: The different types of perseveration are likely to reflect the progressive deterioration of different brain regions in AD... - Post-stroke depression, executive dysfunction and functional outcomeT Pohjasvaara
Memory Research Unit, Department of Clinical Neuroscience, Helsinki University Central Hospital, Finland
Eur J Neurol 9:269-75. 2002..Executive measures may detect patients at risk of dementia and disability post-stroke... - Limitations of clinical criteria for the diagnosis of vascular dementia in clinical trials. Is a focus on subcortical vascular dementia a solution?T Erkinjuntti
Department of Clinical Neurosciences, Helsinki University Central Hospital, Finland
Ann N Y Acad Sci 903:262-72. 2000..Subcortical VaD is expected to show a more predictable clinical picture, natural history, outcomes, and treatment responses... - Preserved stimulus deviance detection in Alzheimer's diseaseE Pekkonen
Department of Neurology, University of Helsinki, and Medical Engineering Centre, Helsinki University Central Hospital, Finland
Neuroreport 12:1649-52. 2001..This suggests that although MMNm is delayed in the left hemisphere, the automatic discrimination to duration change in the auditory cortex is not attenuated in the early stages of AD... - Cognitive decline and treatment options for patients with vascular dementiaT Erkinjuntti
Memory Research Unit, Department of Clinical Neurology, Helsinki University Central Hospital, Helsinki, Finland
Acta Neurol Scand Suppl 178:15-8. 2002..Additionally, functional and behavioral benefits have been reported with the dual-mechanism AChEI galantamine. These studies suggest a potential role for AChEIs in the management of cognitive impairment associated with VaD... - Rivastigmine in patients with Alzheimer's disease and concurrent hypertensionT Erkinjuntti
Department of Neurology, Helsinki University Central Hospital, HYKS, Finland
Int J Clin Pract 56:791-6. 2002..Our data support the hypothesis that rivastigmine provides benefits to patients with or without hypertension, and contribute to the evidence that particular benefits may be observed in those with vascular risk factors...