Aysan Durukan

Summary

Affiliation: Helsinki University Central Hospital
Country: Finland

Publications

  1. doi request reprint Stanniocalcin 1 is important for poststroke functionality, but dispensable for ischemic tolerance
    A Durukan Tolvanen
    Department of Neurology, Helsinki University Central Hospital, Haartmaninkatu 4, 00290, Helsinki, Finland
    Neuroscience 229:49-54. 2013
  2. pmc Preconditioning-induced ischemic tolerance: a window into endogenous gearing for cerebroprotection
    Aysan Durukan
    Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland
    Exp Transl Stroke Med 2:2. 2010
  3. ncbi request reprint Acute ischemic stroke: overview of major experimental rodent models, pathophysiology, and therapy of focal cerebral ischemia
    Aysan Durukan
    Department of Neurology, Helsinki University Central Hospital, Biomedicum Helsinki, POB 700, Haartmaninkatu 8, 00290 Helsinki, Finland
    Pharmacol Biochem Behav 87:179-97. 2007
  4. doi request reprint Post-ischemic blood-brain barrier leakage in rats: one-week follow-up by MRI
    Aysan Durukan
    Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland
    Brain Res 1280:158-65. 2009
  5. ncbi request reprint Rodent models of ischemic stroke: a useful tool for stroke drug development
    Aysan Durukan
    Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland
    Curr Pharm Des 14:359-70. 2008
  6. doi request reprint Post-ischemic leakiness of the blood-brain barrier: a quantitative and systematic assessment by Patlak plots
    Usama Abo-Ramadan
    Department of Neurology, Helsinki University Central Hospital, Haartmaninkatu 4, 00290 Helsinki, Finland
    Exp Neurol 219:328-33. 2009
  7. doi request reprint An optimized mouse model for transient ischemic attack
    Eric Pedrono
    Experimental MRI Laboratory, Biomedicum Helsinki, Finland
    J Neuropathol Exp Neurol 69:188-95. 2010
  8. doi request reprint Decompressive craniectomy for intracerebral hemorrhage
    Ivan Marinkovic
    Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland
    Neurosurgery 65:780-6, 1 p following 786; discussion 786. 2009
  9. doi request reprint Long-term evolution of diffusion tensor indices after temporary experimental ischemic stroke in rats
    Miia Pitkonen
    Experimental MRI Laboratory, Biomedicum Helsinki, Helsinki, Finland
    Brain Res 1445:103-10. 2012
  10. doi request reprint Ischemic stroke in mice and rats
    Aysan Durukan
    Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland
    Methods Mol Biol 573:95-114. 2009

Collaborators

  • Turgut Tatlisumak
  • D Strbian
  • Lauri Soinne
  • R R Reddel
  • Eric Pedrono
  • Ivan Marinkovic
  • Usama Abo-Ramadan
  • Miia Pitkonen
  • A Durukan Tolvanen
  • Shashank Shekhar
  • M Serlachius
  • L C Andersson
  • J A Westberg
  • A C M Chang
  • Khader M Hasan
  • Olga Y Vekovischeva
  • Ertugrul Tatlisumak
  • Esa R Korpi

Detail Information

Publications10

  1. doi request reprint Stanniocalcin 1 is important for poststroke functionality, but dispensable for ischemic tolerance
    A Durukan Tolvanen
    Department of Neurology, Helsinki University Central Hospital, Haartmaninkatu 4, 00290, Helsinki, Finland
    Neuroscience 229:49-54. 2013
    ..STC1 was not crucial for the development of ischemic tolerance triggered by HPC or for preserving BBB integrity but may be involved in functional recovery after stroke...
  2. pmc Preconditioning-induced ischemic tolerance: a window into endogenous gearing for cerebroprotection
    Aysan Durukan
    Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland
    Exp Transl Stroke Med 2:2. 2010
    ..Mimicking the mechanisms of this unique endogenous protection process is therefore a potential strategy for stroke prevention. Perhaps new remedies for stroke are very close, right in our cells...
  3. ncbi request reprint Acute ischemic stroke: overview of major experimental rodent models, pathophysiology, and therapy of focal cerebral ischemia
    Aysan Durukan
    Department of Neurology, Helsinki University Central Hospital, Biomedicum Helsinki, POB 700, Haartmaninkatu 8, 00290 Helsinki, Finland
    Pharmacol Biochem Behav 87:179-97. 2007
    ..In this article, we focus on various rodent animal models, pathogenic mechanisms, and promising therapeutic approaches of ischemic stroke...
  4. doi request reprint Post-ischemic blood-brain barrier leakage in rats: one-week follow-up by MRI
    Aysan Durukan
    Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland
    Brain Res 1280:158-65. 2009
    ..014). The present study confirms that following transient focal cerebral ischemia, BBB leakage to Gd-DTPA is continuous, and during 1 week postreperfusion no BBB closure occurs...
  5. ncbi request reprint Rodent models of ischemic stroke: a useful tool for stroke drug development
    Aysan Durukan
    Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland
    Curr Pharm Des 14:359-70. 2008
    ..Since none of the models can perfectly simulate human stroke, researchers must interpret experimental findings carefully...
  6. doi request reprint Post-ischemic leakiness of the blood-brain barrier: a quantitative and systematic assessment by Patlak plots
    Usama Abo-Ramadan
    Department of Neurology, Helsinki University Central Hospital, Haartmaninkatu 4, 00290 Helsinki, Finland
    Exp Neurol 219:328-33. 2009
    ..These results suggest that after ischemia-reperfusion in rats, BBB leakage is continuous during a 4-week period. Its magnitude diminishes over time and correlates with severity and extent of ischemic injury...
  7. doi request reprint An optimized mouse model for transient ischemic attack
    Eric Pedrono
    Experimental MRI Laboratory, Biomedicum Helsinki, Finland
    J Neuropathol Exp Neurol 69:188-95. 2010
    ....
  8. doi request reprint Decompressive craniectomy for intracerebral hemorrhage
    Ivan Marinkovic
    Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland
    Neurosurgery 65:780-6, 1 p following 786; discussion 786. 2009
    ..Decompressive craniectomy has, however, proven beneficial for large ischemic brain infarction with massive swelling. We hypothesized that craniectomy can improve ICH outcome as well...
  9. doi request reprint Long-term evolution of diffusion tensor indices after temporary experimental ischemic stroke in rats
    Miia Pitkonen
    Experimental MRI Laboratory, Biomedicum Helsinki, Helsinki, Finland
    Brain Res 1445:103-10. 2012
    ..The use of several DT indices may improve accuracy in estimating the age of the brain injury and in detecting ongoing pathological events...
  10. doi request reprint Ischemic stroke in mice and rats
    Aysan Durukan
    Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland
    Methods Mol Biol 573:95-114. 2009
    ....