Penny Nymark

Summary

Affiliation: Finnish Institute of Occupational Health
Country: Finland

Publications

  1. doi Molecular and genetic changes in asbestos-related lung cancer
    Penny Nymark
    Finnish Institute of Occupational Health, 00250 Helsinki, Finland
    Cancer Lett 265:1-15. 2008
  2. doi Accumulation of genomic alterations in 2p16, 9q33.1 and 19p13 in lung tumours of asbestos-exposed patients
    Penny Nymark
    Health and Work Ability, Finnish Institute of Occupational Health, Topeliuksenkatu 41 aA, 00250 Helsinki, Finland
    Mol Oncol 7:29-40. 2013
  3. doi Molecular alterations at 9q33.1 and polyploidy in asbestos-related lung cancer
    Penny Nymark
    Health and Work Ability, Good Practices and Competence, and Work Environment Development, Finnish Institute of Occupational Health, Topeliuksenkatu 41 aA, 00250 Helsinki, Finland
    Clin Cancer Res 15:468-75. 2009
  4. pmc Gene expression profiles in asbestos-exposed epithelial and mesothelial lung cell lines
    Penny Nymark
    Health and Work Ability, Biological Mechanisms and Prevention of Work related Diseases, Finnish Institute of Occupational Health, Helsinki, Finland
    BMC Genomics 8:62. 2007
  5. doi Genotoxicity of polyvinylpyrrolidone-coated silver nanoparticles in BEAS 2B cells
    Penny Nymark
    Nanosafety Research Center and Safe New Technologies, Work Environment Development, Finnish Institute of Occupational Health, Helsinki, Finland
    Toxicology 313:38-48. 2013
  6. ncbi CDK4 is a probable target gene in a novel amplicon at 12q13.3-q14.1 in lung cancer
    Harriet Wikman
    Department of Occupational Medicine, Finnish Institute of Occupational Health, Helsinki, Finland
    Genes Chromosomes Cancer 42:193-9. 2005
  7. ncbi Identification of specific gene copy number changes in asbestos-related lung cancer
    Penny Nymark
    Department of Pathology, Haartman Institute, University of Helsinki and Helsinki University Central Hospital Diagnostics Laboratory, Helsinki University Central Hospital, Finland
    Cancer Res 66:5737-43. 2006

Detail Information

Publications7

  1. doi Molecular and genetic changes in asbestos-related lung cancer
    Penny Nymark
    Finnish Institute of Occupational Health, 00250 Helsinki, Finland
    Cancer Lett 265:1-15. 2008
    ..Specific asbestos-associated molecular signatures can assist the development of early biomarkers, molecular diagnosis, and molecular targeted treatments for asbestos-exposed lung cancer patients...
  2. doi Accumulation of genomic alterations in 2p16, 9q33.1 and 19p13 in lung tumours of asbestos-exposed patients
    Penny Nymark
    Health and Work Ability, Finnish Institute of Occupational Health, Topeliuksenkatu 41 aA, 00250 Helsinki, Finland
    Mol Oncol 7:29-40. 2013
    ..These alterations form the basis for the development of a combinatorial molecular assay that could be used to identify asbestos-related LC...
  3. doi Molecular alterations at 9q33.1 and polyploidy in asbestos-related lung cancer
    Penny Nymark
    Health and Work Ability, Good Practices and Competence, and Work Environment Development, Finnish Institute of Occupational Health, Topeliuksenkatu 41 aA, 00250 Helsinki, Finland
    Clin Cancer Res 15:468-75. 2009
    ..In addition, the ploidy level of the tumors was studied...
  4. pmc Gene expression profiles in asbestos-exposed epithelial and mesothelial lung cell lines
    Penny Nymark
    Health and Work Ability, Biological Mechanisms and Prevention of Work related Diseases, Finnish Institute of Occupational Health, Helsinki, Finland
    BMC Genomics 8:62. 2007
    ..A canonical correlation analysis was applied to identify correlations between the cell lines, and a Gene Ontology analysis method for the identification of enriched, differentially expressed biological processes...
  5. doi Genotoxicity of polyvinylpyrrolidone-coated silver nanoparticles in BEAS 2B cells
    Penny Nymark
    Nanosafety Research Center and Safe New Technologies, Work Environment Development, Finnish Institute of Occupational Health, Helsinki, Finland
    Toxicology 313:38-48. 2013
    ....
  6. ncbi CDK4 is a probable target gene in a novel amplicon at 12q13.3-q14.1 in lung cancer
    Harriet Wikman
    Department of Occupational Medicine, Finnish Institute of Occupational Health, Helsinki, Finland
    Genes Chromosomes Cancer 42:193-9. 2005
    ..Although CDK4 amplification seems to be a relatively rare event (4.3%) in lung tumors, it indicates the significance of the RB1-CCND1 pathway in lung tumorigenesis...
  7. ncbi Identification of specific gene copy number changes in asbestos-related lung cancer
    Penny Nymark
    Department of Pathology, Haartman Institute, University of Helsinki and Helsinki University Central Hospital Diagnostics Laboratory, Helsinki University Central Hospital, Finland
    Cancer Res 66:5737-43. 2006
    ..08), which may imply preferentially caused DNA damage at these sites. Our findings are the first evidence, indicating that asbestos exposure may produce a specific DNA damage profile...