A Karjalainen

Summary

Affiliation: Finnish Institute of Occupational Health
Country: Finland

Publications

  1. ncbi request reprint Risk of asthma among Finnish patients with occupational rhinitis
    Antti Karjalainen
    Department of Epidemiology and Biostatistics, Finnish Institute of Occupational Health, Helsinki, Finland
    Chest 123:283-8. 2003
  2. ncbi request reprint The risk of asthma among Finnish patients with farmer's lung
    Antti Karjalainen
    Department of Epidemiology and Biostatistics, Finnish Institute of Occupational Health, Topeliuksenkatu 41aA, 00250 Helsinki, Finland
    Int Arch Occup Environ Health 75:587-90. 2002
  3. ncbi request reprint Exploration of asthma risk by occupation--extended analysis of an incidence study of the Finnish population
    Antti Karjalainen
    Finnish Institute of Occupational Health, Department of Epidemiology and Biostatistics, Helsinki
    Scand J Work Environ Health 28:49-57. 2002
  4. ncbi request reprint Incidence of occupational asthma by occupation and industry in Finland
    A Karjalainen
    Department of Epidemiology and Biostatistics, Finnish Institute of Occupational Health, Helsinki, Finland
    Am J Ind Med 37:451-8. 2000
  5. ncbi request reprint Work is related to a substantial portion of adult-onset asthma incidence in the Finnish population
    A Karjalainen
    Finnish Institute of Occupational Health, Department of Epidemiology and Biostatistics, Helsinki, Finland
    Am J Respir Crit Care Med 164:565-8. 2001
  6. pmc Pleural plaques and exposure to mineral fibres in a male urban necropsy population
    A Karjalainen
    Institute of Occupational Health, Helsinki, Finland
    Occup Environ Med 51:456-60. 1994
  7. pmc DNA copy number loss and allelic imbalance at 2p16 in lung cancer associated with asbestos exposure
    E Kettunen
    Health and Work Ability, Finnish Institute of Occupational Health, Helsinki, Finland
    Br J Cancer 100:1336-42. 2009
  8. ncbi request reprint Excess incidence of asthma among Finnish cleaners employed in different industries
    A Karjalainen
    Finnish Institute of Occupational Health, Dept of Epidemiology and Biostatistics, Helsinki
    Eur Respir J 19:90-5. 2002
  9. ncbi request reprint Lung cancer and past occupational exposure to asbestos. Role of p53 and K-ras mutations
    K Husgafvel-Pursiainen
    Departments of Industrial Hygiene and Toxicology, Epidemiology and Biostatistics, and Occupational Medicine, Finnish Institute of Occupational Health, Helsinki, Finland
    Am J Respir Cell Mol Biol 20:667-74. 1999
  10. ncbi request reprint Asbestos and cancer in Finland
    M S Huuskonen
    Finnish Institute of Occupational Health, Helsinki, Finland
    Med Lav 86:426-34. 1995

Collaborators

Detail Information

Publications28

  1. ncbi request reprint Risk of asthma among Finnish patients with occupational rhinitis
    Antti Karjalainen
    Department of Epidemiology and Biostatistics, Finnish Institute of Occupational Health, Helsinki, Finland
    Chest 123:283-8. 2003
    ..To determine the risk of asthma among patients with occupationally induced rhinitis...
  2. ncbi request reprint The risk of asthma among Finnish patients with farmer's lung
    Antti Karjalainen
    Department of Epidemiology and Biostatistics, Finnish Institute of Occupational Health, Topeliuksenkatu 41aA, 00250 Helsinki, Finland
    Int Arch Occup Environ Health 75:587-90. 2002
    ..To assess the incidence and risk of asthma in patients with farmer's lung in comparison with farm workers without farmer's lung...
  3. ncbi request reprint Exploration of asthma risk by occupation--extended analysis of an incidence study of the Finnish population
    Antti Karjalainen
    Finnish Institute of Occupational Health, Department of Epidemiology and Biostatistics, Helsinki
    Scand J Work Environ Health 28:49-57. 2002
    ..The objective of the study was to determine asthma risks at the most-detailed level of occupational classification in a previously described nationwide follow-up study that included the entire employed workforce of Finland...
  4. ncbi request reprint Incidence of occupational asthma by occupation and industry in Finland
    A Karjalainen
    Department of Epidemiology and Biostatistics, Finnish Institute of Occupational Health, Helsinki, Finland
    Am J Ind Med 37:451-8. 2000
    ..Systematic research on occupation or industry-specific incidence of occupational asthma (OA) is sparse. We calculated the incidence of notified OA by occupation, industry and causative agent in Finland for the years 1989-95...
  5. ncbi request reprint Work is related to a substantial portion of adult-onset asthma incidence in the Finnish population
    A Karjalainen
    Finnish Institute of Occupational Health, Department of Epidemiology and Biostatistics, Helsinki, Finland
    Am J Respir Crit Care Med 164:565-8. 2001
    ..The results indicate that the impact of occupational factors in the inception of adult-onset persistent asthma, and consequently the potential for prevention, is much larger and more widely spread than generally assumed...
  6. pmc Pleural plaques and exposure to mineral fibres in a male urban necropsy population
    A Karjalainen
    Institute of Occupational Health, Helsinki, Finland
    Occup Environ Med 51:456-60. 1994
    ..Due to methodological difficulties in detecting past exposures to chrysotile and such low exposures that may still pose a risk of plaques, the aetiologic fractions calculated in the study probably underestimate the role of asbestos...
  7. pmc DNA copy number loss and allelic imbalance at 2p16 in lung cancer associated with asbestos exposure
    E Kettunen
    Health and Work Ability, Finnish Institute of Occupational Health, Helsinki, Finland
    Br J Cancer 100:1336-42. 2009
    ..1-p16.1 using 14 microsatellite markers and also AI at 2p16 was related to asbestos exposure (P=0.003). Our results suggest that alterations at 2p16 combined with other markers could be useful in diagnosing asbestos-related lung cancer...
  8. ncbi request reprint Excess incidence of asthma among Finnish cleaners employed in different industries
    A Karjalainen
    Finnish Institute of Occupational Health, Dept of Epidemiology and Biostatistics, Helsinki
    Eur Respir J 19:90-5. 2002
    ..Factors inherent to the environment where cleaning is performed or differences in the cleaning agents used may explain the observed differences between industries...
  9. ncbi request reprint Lung cancer and past occupational exposure to asbestos. Role of p53 and K-ras mutations
    K Husgafvel-Pursiainen
    Departments of Industrial Hygiene and Toxicology, Epidemiology and Biostatistics, and Occupational Medicine, Finnish Institute of Occupational Health, Helsinki, Finland
    Am J Respir Cell Mol Biol 20:667-74. 1999
    ..In conclusion, the results may primarily reflect the observed excess of adenocarcinoma in the asbestos- exposed patients, and hence the decrease in p53 mutations and increase in K-ras mutations...
  10. ncbi request reprint Asbestos and cancer in Finland
    M S Huuskonen
    Finnish Institute of Occupational Health, Helsinki, Finland
    Med Lav 86:426-34. 1995
    ..An important objective of research work is to improve early diagnostics, and thereby treatment prospects, in case of asbestos-induced cancers...
  11. ncbi request reprint Epidemiologic estimate of the proportion of fatalities related to occupational factors in Finland
    M Nurminen
    Department of Epidemiology and Biostatistics, Finnish Institute of Occupational Health, Helsinki
    Scand J Work Environ Health 27:161-213. 2001
    ..This study attempts to estimate the proportion of annual deaths related to occupational factors in Finland and considers related methodological issues and associated uncertainties...
  12. ncbi request reprint CYP1A1 levels in lung tissue of tobacco smokers and polymorphisms of CYP1A1 and aromatic hydrocarbon receptor
    S Anttila
    Finnish Institute of Occupational Health, Helsinki, Finland
    Pharmacogenetics 11:501-9. 2001
    ..Our results thus indicate that the interindividual variation of CYP1A1 levels in smokers' lung tissue is not attributable to genetic polymorphisms of CYP1A1 or AHR tested in this study...
  13. ncbi request reprint Cancer incidence and mortality among Finnish asbestos sprayers and in asbestosis and silicosis patients
    P Oksa
    Tampere Regional Institute of Occupational Health, Finland
    Am J Ind Med 31:693-8. 1997
    ..Asbestos-induced occupational cancers are not only diseases of the elderly, since the relative risk is high also for middle-aged people...
  14. ncbi request reprint Biological treatment in rheumatic diseases: results from a longitudinal surveillance: adverse events
    L Konttinen
    Department of Medicine, University of Helsinki, Helsinki, Finland
    Rheumatol Int 26:916-22. 2006
    ..Biological treatment appears safe in the hands of the Finnish rheumatologists...
  15. ncbi request reprint Gene expression and copy number profiling suggests the importance of allelic imbalance in 19p in asbestos-associated lung cancer
    H Wikman
    Finnish Institute of Occupational Health, Helsinki, Finland
    Oncogene 26:4730-7. 2007
    ..008) were found to be carriers of AI in their lung tumors. In the exposed group, AI in 19p was prevalent regardless of the histological tumor type. In adenocarcinomas, AI in 19p appeared to occur independently of the asbestos exposure...
  16. ncbi request reprint Increased expression of high mobility group A proteins in lung cancer
    V K Sarhadi
    Department of Occupational Medicine, Finnish Institute of Occupational Health, Helsinki, Finland
    J Pathol 209:206-12. 2006
    ..As HMGA proteins were expressed in about 90% of lung carcinomas and their expression was inversely associated with survival, they may provide useful markers for lung cancer diagnosis and prognosis...
  17. ncbi request reprint Asthma incidence in wood-processing industries in Finland in a register-based population study
    Pirjo Heikkilä
    Finnish Institute of Occupational Health, Topeliuksenkatu 41 aA, FI 00250 Helsinki, Finland
    Scand J Work Environ Health 34:66-72. 2008
    ..Exposure to wood dust was under special scrutiny...
  18. ncbi request reprint Evaluation of a national register on occupational exposure to carcinogens: effectiveness in the prevention of occupational cancer, and cancer risks among the exposed workers
    Timo Kauppinen
    Finnish Institute of Occupational Health, Topeliuksenkatu 41 a A, 00250 Helsinki, Finland
    Ann Occup Hyg 51:463-70. 2007
    ....
  19. ncbi request reprint Different measures of asbestos exposure in estimating risk of lung cancer and mesothelioma among construction workers
    Kari Koskinen
    Uusimaa Regional Institute of Occupational Health, Helsinki, Finland
    J Occup Environ Med 44:1190-6. 2002
    ..The risk of lung cancer was the highest in insulators (RR 3.7, 95% CI = 1.4-9.9). Occupation, expert-evaluated cumulative exposure, and lung fibrosis are useful indicators of lung cancer risk among construction workers...
  20. pmc Indoor dampness and molds and development of adult-onset asthma: a population-based incident case-control study
    Maritta S Jaakkola
    Finnish Institute of Occupational Health, Helsinki, Finland
    Environ Health Perspect 110:543-7. 2002
    ..1% (95% confidence interval, 1.0-56.9%) among the exposed. Present results provide new evidence of the relation between workplace exposure to indoor molds and adult-onset asthma...
  21. ncbi request reprint [The changing spectrum of occupational diseases]
    Antti Karjalainen
    Duodecim 119:1303-4. 2003
  22. ncbi request reprint Incidence of cancer among the participants of the Finnish Asbestos Screening Campaign
    Kari Koskinen
    Uusimaa Regional Institute of Occupational Health, Helsinki, Finland
    Scand J Work Environ Health 29:64-70. 2003
    ..The bulk of the asbestos epidemic results come, however, from past intermittent exposures during asbestos product use. This study concentrated on estimating the risk of cancer in such a population...
  23. ncbi request reprint Incidence of asthma among Finnish construction workers
    Antti Karjalainen
    Finnish Institute of Occupational Health, Topeliuksenkatu 41 aA, FIN 00250 Helsinki, Finland
    J Occup Environ Med 44:752-7. 2002
    ..Construction industry workers have an increased risk of adult-onset persistent asthma and cases of occupational asthma caused by well-established causative agents have only a minor contribution to this overall asthma excess...
  24. ncbi request reprint Employment status of Finnish cancer patients in 1997
    Taina Taskila-Abrandt
    Department of Epidemiology and Biostatistics, Finnish Institute of Occupational Health, Helsinki, Finland
    Psychooncology 14:221-6. 2005
    ..Early retirement is common among people with highly disabling cancer or poor prognosis, but in general, the employment of cancer survivors seems optimistic...
  25. ncbi request reprint Estimating the induction period of pleural mesothelioma from aggregate data on asbestos consumption
    Markku Nurminen
    Department of Epidemiology and Biostatistics, Finnish Institute of Occupational Health, Helsinki, Finland
    J Occup Environ Med 45:1107-15. 2003
    ..The ecologic analysis suggested that the most probable estimate for the mean induction period (use versus morbidity at society level) is approximately 25 years...
  26. ncbi request reprint Identification of specific gene copy number changes in asbestos-related lung cancer
    Penny Nymark
    Department of Pathology, Haartman Institute, University of Helsinki and Helsinki University Central Hospital Diagnostics Laboratory, Helsinki University Central Hospital, Finland
    Cancer Res 66:5737-43. 2006
    ..08), which may imply preferentially caused DNA damage at these sites. Our findings are the first evidence, indicating that asbestos exposure may produce a specific DNA damage profile...
  27. ncbi request reprint Ecological association between asbestos-related diseases and historical asbestos consumption: an international analysis
    Ro Ting Lin
    Department of Environmental Epidemiology, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Yahatanishiku, Kitakyushu, 807 8555, Japan
    Lancet 369:844-9. 2007
    ..Our aim was to assess the ecological association between national death rates from diseases associated with asbestos and historical consumption of asbestos...
  28. ncbi request reprint A cross-country comparative overview of the asbestos situation in ten Asian countries
    Ken Takahashi
    Department of Epidemiology, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Kitakyushu City, Japan
    Int J Occup Environ Health 9:244-8. 2003
    ..Hence the experience of industrialized countries regarding asbestos and its use should be utilized to the fullest to improve the situation worldwide...