Protective effect of melatonin on beta-amyloid-induced apoptosis in rat astroglioma C6 cells and its mechanismZheng Feng
Department of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 10050, People s Republic of China
Free Radic Biol Med 37:1790-801. 2004
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- Early melatonin supplementation alleviates oxidative stress in a transgenic mouse model of Alzheimer's disease
Zheng Feng
Department of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, No 1 Xiannong Tan Street, Beijing 10050, Peoples s Republic of China
Free Radic Biol Med 40:101-9. 2006
..In sharp contrast to conventional antioxidants, melatonin crosses the blood-brain barrier, is relatively devoid of toxicity, and constitutes a potential therapeutic candidate in AD treatment...
- A drug-based intervention study on the importance of buffaloes for human Schistosoma japonicum infection around Poyang Lake, People's Republic of China
Jiagang Guo
Institute of Parasitic Diseases, Chinese Centre for Disease Control and Prevention, Shanghai, People's Republic of China
Am J Trop Med Hyg 74:335-41. 2006
..Mathematical modeling predicted that buffalo are responsible for 75% of human transmission in Jishan...
- Melatonin reduces amyloid beta-induced apoptosis in pheochromocytoma (PC12) cells
Zheng Feng
Department of Pharmacology, Institute of Materia Medica Chinese Academy of Medical Sciences and Peking Union Medical College, No 1 Xiannong Tan Street, Beijing, 10050, P R China
J Pineal Res 37:257-66. 2004
..The use of melatonin or its derived analogs should be explored as a therapeutic approach in AD...
- Long-term effects of melatonin or 17 beta-estradiol on improving spatial memory performance in cognitively impaired, ovariectomized adult rats
Zheng Feng
Department of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 10050, P R China
J Pineal Res 37:198-206. 2004
..Early long-term melatonin application is a promising strategy which could potentially be applied in a clinic setting...
- Long-term melatonin or 17beta-estradiol supplementation alleviates oxidative stress in ovariectomized adult rats
Zheng Feng
Department of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, No.1 Xiannong Tan Street, Beijing 10050, People's Republic of China
Free Radic Biol Med 39:195-204. 2005
..Early, long-term melatonin application is a promising strategy which could potentially be applied in a clinical setting...
- Beneficial effects of melatonin in experimental models of Alzheimer disease
Yong Cheng
Department of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
Acta Pharmacol Sin 27:129-39. 2006
..Several groups have shown that melatonin has an inhibitory effect on tau protein hyperphosphorylation. These actions may potentially slow down or stop the progression of dementia...
- Melatonin alleviates behavioral deficits associated with apoptosis and cholinergic system dysfunction in the APP 695 transgenic mouse model of Alzheimer's disease
Zheng Feng
Department of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P.R. China
J Pineal Res 37:129-36. 2004
..Early rational melatonin interventions may be one of the most promising strategies in the development of approaches to retard or prevent Abeta-mediated disease progression...
- DNA sequences of Paragonimus skrjabini populations from five provinces in China
Ming Gang Chen
Department of Schistosomiasis, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai 200025, China
Chin Med J (Engl) 117:219-24. 2004
..To study differences among Paragonimus skrjabini (P. skrjabini) populations from five provinces in China (Guangdong, Fujian, Yunnan, Hubei, and Sichuan) and Paragonimus szechuanensis...
A seroepidemiological survey of Taenia solium cysticercosis in Nabo, Guangxi Zhuang Autonomous Region, ChinaJoon Yong Chung
PharmacoGenomics Research Center, Inje University, Busan, Korea
Korean J Parasitol 43:135-9. 2005
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- Pathway and gene ontology based analysis of gene expression in a rat model of cerebral ischemic tolerance
Zheng Feng
Department of Anesthesiology, University of California, San Diego, USA
Brain Res 1177:103-23. 2007
..Our data suggest that the tolerant brain responds to subsequent ischemic stress by partially downregulating inflammatory and upregulating protein synthesis and energy metabolism pathways...
- Glomerular aging in females is a multi-stage reversible process mediated by phenotypic changes in progenitors
Zheng Feng
Department of Medicine, Division of Nephrology, Vascular Biology Institute, University of Miami School of Medicine, Florida, USA
Am J Pathol 167:355-63. 2005
..Thus, glomerular hypertrophy and sclerosis in aging females is a multistage process, is reversible, and may be determined by the phenotype of bone marrow-derived progenitor cells...
- A cluster-randomized bovine intervention trial against Schistosoma japonicum in the People's Republic of China: design and baseline results
Darren J Gray
Australian Centre for International and Tropical Health and Nutrition, The University of Queensland and The Queensland Institute of Medical Research, Brisbane, Queensland, Australia
Am J Trop Med Hyg 77:866-74. 2007
..japonicum. The combination of such a vaccine with other control strategies could potentially eliminate S. japonicum from southern China...
- Mathematical modelling of schistosomiasis japonica: comparison of control strategies in the People's Republic of China
Gail M Williams
Australian Centre for International and Tropical Health and Nutrition, The Queensland Institute of Medical Research, The University of Queensland, Brisbane, Australia
Acta Trop 82:253-62. 2002
..If it is accompanied by an initial period of human treatment and by a 45% improvement in human sanitation or a 30% reduction in contaminated water contact by humans, elimination is then possible...
- [Study on DNA sequences of Paragonimus skrjabini populations from five provinces in China]
Ai-li Cui
Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai 200025
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 21:71-5. 2003
..Also found was that P. veocularis and P. miyazakii may be the synonyms of P. skrjabini. As a separate species, P. heterotremus was found to be closer to P. skrjabini and quite a distance from P. westermani in the genetic relationship...
- [Taxonomic status in DNA sequences of five species of genus Paragonimus]
Ai-li Cui
Institute of Parasitic Disease, Chinese Center for Disease Control and Prevention, Shanghai 200025
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 21:27-30. 2003
..menglaensis, P. bangkokensis and P. xiangshanensis are closer in the genetic relationship. Their taxonomic status lies between P. skrjabini and P. westermani. The genetic relationship between P. hokuoensis and P. skrjabini is very close...
- Application of remote sensing for surveillance of snail habitats in Poyang Lake, China
Wei-Ping Wu
Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Centre for Malaria, Schistosomiasis and Filariasis, Shanghai 200025
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 20:205-8. 2002
..Classified images can be used to identify snail habitats, determine their areas, and monitor snail habitat changes caused by annual fluctuations of key environmental factors...
- [Improvement in the preparation of Paragonimus westermani chromosome for karyotype analysis]
Shao-hong Chen
Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai 200025
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 20:155-7. 2002
..westermani is 22, and the karyotype is 2m + 6Sm + 14t chromosome. CONCLUSION: The improved technique of chromosome preparation is feasible to operate and the chromosome is clear enough for karyotype analysis...
- [Study on genomic diversity among different isolates of Schistosoma japonicum in China]
Chi-ping Qiu
Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai 200025
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 20:79-82. 2002
..In individual mitochondrial gene, type I of ND1 was fixedly accompanied with type I of CO1 gene, and type II of ND1 with type II of CO1. CONCLUSION: There are two different genetypes of ND1 and CO1 genes of S. japonicum in China...
- Identification of Taenia asiatica in China: molecular, morphological, and epidemiological analysis of a Luzhai isolate
Keeseon S Eom
Department of Parasitology and Medical Research Institute, Chungbuk National University College of Medicine, Chongju, Chungbuk 360 763, South Korea
J Parasitol 88:758-64. 2002
..These collective data demonstrate that T. asiatica is sympatrically distributed with the other 2 species of Taenia in the human host in mainland China...
- DNA-based vaccines protect against zoonotic schistosomiasis in water buffalo
Akram A Da'Dara
Department of Immunology and Infectious Diseases, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
Vaccine 26:3617-25. 2008
..Indeed, mathematical modeling of SjCTPI-Hsp70 and SjC23-Hsp70 alone and in conjunction with human chemotherapy showed a significant reduction in transmission almost to the point of elimination...
