Robert E Featherstone

Summary

Publications

  1. pmc Electrophysiological and behavioral responses to ketamine in mice with reduced Akt1 expression
    Robert E Featherstone
    Department of Psychiatry, Translational Neuroscience Program, School of Medicine, University of Pennsylvania, 125 South 31st Street, Philadelphia, PA 19104, USA
    Psychopharmacology (Berl) 227:639-49. 2013
  2. doi request reprint Gestational treatment with methylazoxymethanol (MAM) that disrupts hippocampal-dependent memory does not alter behavioural response to cocaine
    Robert E Featherstone
    Section of Biopsychology, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Pharmacol Biochem Behav 93:382-90. 2009
  3. doi request reprint Subchronic ketamine treatment leads to permanent changes in EEG, cognition and the astrocytic glutamate transporter EAAT2 in mice
    Robert E Featherstone
    Department of Psychiatry, Translational Neuroscience Program, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Neurobiol Dis 47:338-46. 2012
  4. pmc Pyramidal cell selective ablation of N-methyl-D-aspartate receptor 1 causes increase in cellular and network excitability
    Valerie M Tatard-Leitman
    Translational Neuroscience Program, University of Pennsylvania, Philadelphia, Pennsylvania Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania
    Biol Psychiatry 77:556-68. 2015
  5. doi request reprint A sensitizing regimen of amphetamine that disrupts attentional set-shifting does not disrupt working or long-term memory
    Robert E Featherstone
    Section of Biopsychology, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada M5T 1R8
    Behav Brain Res 189:170-9. 2008
  6. ncbi request reprint Gestational methylazoxymethanol acetate treatment impairs select cognitive functions: parallels to schizophrenia
    Robert E Featherstone
    Section of Biopsychology, Centre for Addiction and Mental Health, Toronto, ON, Canada
    Neuropsychopharmacology 32:483-92. 2007
  7. doi request reprint Nicotine normalizes event related potentials in COMT-Val-tg mice and increases gamma and theta spectral density
    Yufei A Cao
    ranslational Neuroscience Program, Department of Psychiatry, University of Pennsylvania, PA, USA
    Behav Neurosci 126:332-43. 2012
  8. pmc Parvalbumin cell ablation of NMDA-R1 causes increased resting network excitability with associated social and self-care deficits
    Eddie N Billingslea
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA
    Neuropsychopharmacology 39:1603-13. 2014
  9. pmc Nicotine receptor subtype-specific effects on auditory evoked oscillations and potentials
    Robert E Featherstone
    Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 7:e39775. 2012
  10. doi request reprint EEG biomarkers of target engagement, therapeutic effect, and disease process
    Robert E Featherstone
    Translational Neuroscience Program, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania
    Ann N Y Acad Sci 1344:12-26. 2015

Collaborators

Detail Information

Publications10

  1. pmc Electrophysiological and behavioral responses to ketamine in mice with reduced Akt1 expression
    Robert E Featherstone
    Department of Psychiatry, Translational Neuroscience Program, School of Medicine, University of Pennsylvania, 125 South 31st Street, Philadelphia, PA 19104, USA
    Psychopharmacology (Berl) 227:639-49. 2013
    ....
  2. doi request reprint Gestational treatment with methylazoxymethanol (MAM) that disrupts hippocampal-dependent memory does not alter behavioural response to cocaine
    Robert E Featherstone
    Section of Biopsychology, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Pharmacol Biochem Behav 93:382-90. 2009
    ..MAM treatment disrupted performance of the win-shift task but did not alter cocaine self-administration or cocaine-induced locomotion. Implications of these results for the MAM model of schizophrenia are discussed...
  3. doi request reprint Subchronic ketamine treatment leads to permanent changes in EEG, cognition and the astrocytic glutamate transporter EAAT2 in mice
    Robert E Featherstone
    Department of Psychiatry, Translational Neuroscience Program, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Neurobiol Dis 47:338-46. 2012
    ....
  4. pmc Pyramidal cell selective ablation of N-methyl-D-aspartate receptor 1 causes increase in cellular and network excitability
    Valerie M Tatard-Leitman
    Translational Neuroscience Program, University of Pennsylvania, Philadelphia, Pennsylvania Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania
    Biol Psychiatry 77:556-68. 2015
    ..However, this computational model has not been tested experimentally and the molecular mechanisms underlying pyramidal neuron dysfunction in SZ remain unclear...
  5. doi request reprint A sensitizing regimen of amphetamine that disrupts attentional set-shifting does not disrupt working or long-term memory
    Robert E Featherstone
    Section of Biopsychology, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada M5T 1R8
    Behav Brain Res 189:170-9. 2008
    ....
  6. ncbi request reprint Gestational methylazoxymethanol acetate treatment impairs select cognitive functions: parallels to schizophrenia
    Robert E Featherstone
    Section of Biopsychology, Centre for Addiction and Mental Health, Toronto, ON, Canada
    Neuropsychopharmacology 32:483-92. 2007
    ..These results support the notion that MAM treatment may simulate some aspects of schizophrenic cognition...
  7. doi request reprint Nicotine normalizes event related potentials in COMT-Val-tg mice and increases gamma and theta spectral density
    Yufei A Cao
    ranslational Neuroscience Program, Department of Psychiatry, University of Pennsylvania, PA, USA
    Behav Neurosci 126:332-43. 2012
    ..Nicotine restored normal event-related activity among COMT-Val-tg mice, suggesting one mechanism through which nicotine may normalize cognitive function among people with the high-activity allele...
  8. pmc Parvalbumin cell ablation of NMDA-R1 causes increased resting network excitability with associated social and self-care deficits
    Eddie N Billingslea
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA
    Neuropsychopharmacology 39:1603-13. 2014
    ..Although previous data suggest that MPEP may be beneficial for core features of autism spectrum disorders, current data suggest that such effects require intact function of NMDAR on PV interneurons. ..
  9. pmc Nicotine receptor subtype-specific effects on auditory evoked oscillations and potentials
    Robert E Featherstone
    Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 7:e39775. 2012
    ..Although the role of nicotine receptor subtypes in augmentation of ERPs has received some attention, less is known about how these receptor subtypes regulate the effect of nicotine on evoked gamma activity...
  10. doi request reprint EEG biomarkers of target engagement, therapeutic effect, and disease process
    Robert E Featherstone
    Translational Neuroscience Program, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania
    Ann N Y Acad Sci 1344:12-26. 2015
    ..Translational EEG biomarkers reflect target engagement and can contribute to the design of more efficient drug trials, likely accelerating the development of new therapeutics for central nervous system disorders. ..