Ammad Ahmad Farooqi



  1. Attar R, Sajjad F, Qureshi M, Tahir F, Hussain E, Fayyaz S, et al. TRAIL based therapy: overview of mesenchymal stem cell based delivery and miRNA controlled expression of TRAIL. Asian Pac J Cancer Prev. 2014;15:6495-7 pubmed
  2. Rana A, Attar R, Qureshi M, Gasparri M, Donato V, Ali G, et al. Dealing naturally with stumbling blocks on highways and byways of TRAIL induced signaling. Asian Pac J Cancer Prev. 2014;15:8041-6 pubmed
    ..The data obtained from pre-clinical studies will be helpful in translation of information from benchtop to the bedside. ..
  3. Aras A, Iqbal M, Naqvi S, Gercek Y, Boztas K, Gasparri M, et al. Anticancer activity of essential oils: targeting of protein networks in cancer cells. Asian Pac J Cancer Prev. 2014;15:8047-50 pubmed
    ..Encouraging results obtained from preclinical studies have attracted considerable attention and various phytochemicals have entered into clinical trials. ..
  4. Farooqi A, Attar R, Gasparri M. Drugs from marine sources: modulation of TRAIL induced apoptosis in cancer cells. Asian Pac J Cancer Prev. 2014;15:9045-7 pubmed
    ..In this commentary, a list of marine derived compounds reported to induce apoptosis is discussed. ..
  5. Qureshi M, Romero M, Attar R, Javed Z, Farooqi A. TRAIL and Bortezomib: killing cancer with two stones. Asian Pac J Cancer Prev. 2015;16:1671-4 pubmed
  6. Farooqi A, Attar R, Arslan B, Romero M, ul Haq M, Qadir M. Recently emerging signaling landscape of ataxia-telangiectasia mutated (ATM) kinase. Asian Pac J Cancer Prev. 2014;15:6485-8 pubmed
    ..Moreover, crosstalk between autophagy and ATM is also discussed with focus on how autophagy inhibition induces apoptosis in cancer cells. ..
  7. Farooqi A, Wang Z, Hasnain S, Attar R, Aslam A, Mansoor Q, et al. Citrus fruits and their bioactive ingredients: leading four horsemen from front. Asian Pac J Cancer Prev. 2015;16:2575-80 pubmed
    ..We also discuss how oncogenic protein networks are targeted in cancer cells and how these findings may be verified in preclinical studies. ..
  8. Sarwar R, Mansoor Q, Farooqi A, Shahzad S, Fayyaz S, Ismail M. Genetic variants in the tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) do not contribute but Death Receptor (DR4) genes may contribute to susceptibility to head and neck cancer in Pakistani population. Cell Mol Biol (Noisy-le-grand). 2015;61:53-6 pubmed
    ..5% in controls. T allele was 0.54% in patients and 0.5% in controls. Future studies must converge on somatic mutations, epigenetic mutations and expression analysis of TRAIL and DR4 to get a step closer to individualized medicine. ..
  9. Lin X, Aslam A, Attar R, Yaylim I, Qureshi M, Hasnain S, et al. Signaling lansdscape of prostate cancer. Cell Mol Biol (Noisy-le-grand). 2016;62:45-50 pubmed
    ..In this review we have attempted to provide an overview of most recent advancements in our knowledge related to different signaling cascades including TGF, SHH, Notch, JAK-STAT in prostate cancer progression and development. ..

More Information


  1. Lin X, Farooqi A, Qureshi M, Romero M, Tabassum S, Ismail M. Prostate Cancer Stem Cells: Viewing Signaling Cascades at a Finer Resolution. Arch Immunol Ther Exp (Warsz). 2016;64:217-23 pubmed publisher
    ..We partition this multicomponent review into how different signaling cascades operate in cancer stem cells and how bioactive ingredients isolated from natural sources may modulate signaling network. ..
  2. Jabeen S, Qureshi M, Javed Z, Iqbal M, Ismail M, Farooqi A. Kisspeptin Mediated Signaling in Cancer. Curr Top Med Chem. 2016;16:2471-6 pubmed
    ..There is also a lack of evidence regarding natural agents that mediate upregulation or downregulation of KISS1. Increasing the knowledge of the KISS1/KISS1R signaling axis will be helpful in achieving personalized medicine. ..
  3. Farooqi A, Gadaleta C, Ranieri G, Fayyaz S, Marech I. New Frontiers in Promoting TRAIL-Mediated Cell Death: Focus on Natural Sensitizers, miRNAs, and Nanotechnological Advancements. Cell Biochem Biophys. 2016;74:3-10 pubmed publisher
    ..Comprehensive knowledge of genetics and proteomics of TRAIL-based signaling network obtained from cancer patients of different populations will be helpful in getting a step closer to personalized medicine. ..
  4. Farooqi A, Bhatti S, Nawaz A, Khalid A. One size fits all in prostate cancer: a story tale whose time has come and gone. Int J Biol Markers. 2011;26:75-81 pubmed publisher
    ..In this review, we have developed a roadmap of the "recalcitrant prostate cancer proteome" to recognize the aspects of prostate cancer that may be helpful in effectively translating these findings to the clinic...
  5. Farooqi A, Waseem S, Ashraf M, Iqbal M, Bhatti S. TRAIL and guardian angel of genome integrity: ATM boards TRAIL blazer. J Cancer Res Clin Oncol. 2011;137:1283-7 pubmed publisher
    ..An insight of the orchestration between DNA damage-based molecular responses and TRAIL provides an understanding of the mechanisms that cause apoptosis and may provide rationale for the development of novel therapeutic strategies. ..
  6. Farooqi A, De Rosa G. TRAIL and microRNAs in the treatment of prostate cancer: therapeutic potential and role of nanotechnology. Appl Microbiol Biotechnol. 2013;97:8849-57 pubmed publisher