- Cognitive impairments caused by oxaliplatin and 5-fluorouracil chemotherapy are ameliorated by physical activityJoanna E Fardell
School of Psychology, University of Sydney, Brennan MacCallum Building A18, Sydney, NSW 2006, Australia
Psychopharmacology (Berl) 220:183-93. 2012..Which chemotherapy agents cause problems with cognition and the aetiology of the impairment is unknown. Furthermore, there is no proven treatment...
- Single high dose treatment with methotrexate causes long-lasting cognitive dysfunction in laboratory rodentsJoanna E Fardell
School of Psychology, University of Sydney, Australia
Pharmacol Biochem Behav 97:333-9. 2010..These results show that chemotherapy produces persistent but subtle cognitive deficits in laboratory rodents that vary with time post treatment...
- The chemotherapy agent oxaliplatin impairs the renewal of fear to an extinguished conditioned stimulus in ratsMelissa J Sharpe
School of Psychology, University of NSW, Australia
Behav Brain Res 227:295-9. 2012..This profile of impairment is consistent with hippocampal damage, and may also involve frontal cortical, amygdalar and thalamic regions important for context discrimination and the contextual modulation of behaviour...