Jian Gao Fan

Summary

Publications

  1. ncbi Prevention of hepatocellular carcinoma in nonviral-related liver diseases
    Jian Gao Fan
    Department of Gastroenterology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
    J Gastroenterol Hepatol 24:712-9. 2009
  2. ncbi Epidemiology of non-alcoholic fatty liver disease in China
    Jian Gao Fan
    Department of Gastroenterology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China
    J Hepatol 50:204-10. 2009
  3. ncbi Alcohol consumption and metabolic syndrome among Shanghai adults: a randomized multistage stratified cluster sampling investigation
    Jian Gao Fan
    Center for Fatty Liver Disease, Shanghai First People s Hospital, Jiaotong University, Shanghai 200080, China
    World J Gastroenterol 14:2418-24. 2008
  4. ncbi Clinical features of nonalcoholic fatty liver disease-associated hepatocellular carcinoma
    Xiao Yan Duan
    Department of Gastroenterology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
    Hepatobiliary Pancreat Dis Int 11:18-27. 2012
  5. ncbi Impact of non-alcoholic fatty liver disease on accelerated metabolic complications
    Jian Gao Fan
    Department of Gastroenterology, Shanghai First People s Hospital, Shanghai Jiaotong University, Shanghai, China
    J Dig Dis 9:63-7. 2008
  6. ncbi [Effect of body weight mass and its change on the incidence of nonalcoholic fatty liver disease]
    Jian Gao Fan
    Department of Gastroenterology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China
    Zhonghua Gan Zang Bing Za Zhi 18:676-9. 2010
  7. ncbi Metabolic syndrome and non-alcoholic fatty liver disease: Asian definitions and Asian studies
    Jian Gao Fan
    Center for Fatty Liver Disease and Department of Endocrinology, Shanghai First People s Hospital, Jiaotong University, Shanghai 200080, China
    Hepatobiliary Pancreat Dis Int 6:572-8. 2007
  8. ncbi The importance of metabolic factors for the increasing prevalence of fatty liver in Shanghai factory workers
    Jian Gao Fan
    Center for Fatty Liver, Department of Gastroenterology, Shanghai First People s Hospital, Jiaotong University, Shanghai, China
    J Gastroenterol Hepatol 22:663-8. 2007
  9. ncbi Fatty liver and the metabolic syndrome among Shanghai adults
    Jian Gao Fan
    Center for Fatty Liver, Shanghai First People s Hospital Affiliated JiaoTong University, Shanghai, China
    J Gastroenterol Hepatol 20:1825-32. 2005
  10. ncbi Prevalence of and risk factors for fatty liver in a general population of Shanghai, China
    Jian Gao Fan
    Center for Fatty Liver, Shanghai First People s Hospital, Jiaotong University, Shanghai, China
    J Hepatol 43:508-14. 2005

Collaborators

Detail Information

Publications52

  1. ncbi Prevention of hepatocellular carcinoma in nonviral-related liver diseases
    Jian Gao Fan
    Department of Gastroenterology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
    J Gastroenterol Hepatol 24:712-9. 2009
    ....
  2. ncbi Epidemiology of non-alcoholic fatty liver disease in China
    Jian Gao Fan
    Department of Gastroenterology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China
    J Hepatol 50:204-10. 2009
    ..Public health interventions are therefore indicated to halt or reverse the national trend of obesity in China so as to improve liver as well as metabolic health...
  3. ncbi Alcohol consumption and metabolic syndrome among Shanghai adults: a randomized multistage stratified cluster sampling investigation
    Jian Gao Fan
    Center for Fatty Liver Disease, Shanghai First People s Hospital, Jiaotong University, Shanghai 200080, China
    World J Gastroenterol 14:2418-24. 2008
    ..To examine the relations of alcohol consumption to the prevalence of metabolic syndrome in Shanghai adults...
  4. ncbi Clinical features of nonalcoholic fatty liver disease-associated hepatocellular carcinoma
    Xiao Yan Duan
    Department of Gastroenterology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
    Hepatobiliary Pancreat Dis Int 11:18-27. 2012
    ..However, detailed analysis of the clinical features in patients with NAFLD and their association with HCC is lacking. This study aimed to update the clinical features of patients with NAFLD-associated HCC...
  5. ncbi Impact of non-alcoholic fatty liver disease on accelerated metabolic complications
    Jian Gao Fan
    Department of Gastroenterology, Shanghai First People s Hospital, Shanghai Jiaotong University, Shanghai, China
    J Dig Dis 9:63-7. 2008
    ..Future studies might address the question whether earlier adjustment to a more efficient lifestyle or a pharmacological treatment that mobilizes fat out of the liver could reduce these risks...
  6. ncbi [Effect of body weight mass and its change on the incidence of nonalcoholic fatty liver disease]
    Jian Gao Fan
    Department of Gastroenterology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China
    Zhonghua Gan Zang Bing Za Zhi 18:676-9. 2010
    ..To determine the effect of body mass index (BMI) at baseline and its change during follow-up on the incidence of non-alcoholic fatty liver diseases (NAFLD) in apparently healthy adults...
  7. ncbi Metabolic syndrome and non-alcoholic fatty liver disease: Asian definitions and Asian studies
    Jian Gao Fan
    Center for Fatty Liver Disease and Department of Endocrinology, Shanghai First People s Hospital, Jiaotong University, Shanghai 200080, China
    Hepatobiliary Pancreat Dis Int 6:572-8. 2007
    ..In particular, there has been an upsurge in metabolic syndrome in the Asia-Pacific region, although there are critical differences in the extent of adiposity between Eastern and Western populations...
  8. ncbi The importance of metabolic factors for the increasing prevalence of fatty liver in Shanghai factory workers
    Jian Gao Fan
    Center for Fatty Liver, Department of Gastroenterology, Shanghai First People s Hospital, Jiaotong University, Shanghai, China
    J Gastroenterol Hepatol 22:663-8. 2007
    ..To evaluate changes in the prevalence rates of ultrasonographic fatty liver (FL) in a specific population...
  9. ncbi Fatty liver and the metabolic syndrome among Shanghai adults
    Jian Gao Fan
    Center for Fatty Liver, Shanghai First People s Hospital Affiliated JiaoTong University, Shanghai, China
    J Gastroenterol Hepatol 20:1825-32. 2005
    ..To explore the relationship between fatty liver and the metabolic syndrome in the adults of Shanghai and evaluate the value of fatty liver as a marker for risk factor clustering...
  10. ncbi Prevalence of and risk factors for fatty liver in a general population of Shanghai, China
    Jian Gao Fan
    Center for Fatty Liver, Shanghai First People s Hospital, Jiaotong University, Shanghai, China
    J Hepatol 43:508-14. 2005
    ..To determine the prevalence and risk factors of fatty liver (FL) among Shanghai adults...
  11. ncbi Effects of low-calorie diet on steatohepatitis in rats with obesity and hyperlipidemia
    Jian Gao Fan
    Department of Gastroenterology, Shanghai, First People s Hospital, Shanghai 200080, China
    World J Gastroenterol 9:2045-9. 2003
    ..To evaluate the effects of low calorie diet (LCD) on nonalcoholic steatohepatitis (NASH) in rats with obesity and hyperlipidemia...
  12. ncbi What are the risk factors and settings for non-alcoholic fatty liver disease in Asia-Pacific?
    Jian Gao Fan
    Center for Fatty Liver Disease, Shanghai First People s Hospital, Jiaotong University, Shanghai, China
    J Gastroenterol Hepatol 22:794-800. 2007
    ..In addition, a perspective of NAFLD beyond its hepatic consequences is now warranted; this needs to be considered in relation to management guidelines for affected individuals...
  13. ncbi Characterization of high-fat, diet-induced, non-alcoholic steatohepatitis with fibrosis in rats
    Zheng Jie Xu
    Center for Fatty Liver Disease, Shanghai First People s Hospital, Jiao Tong University, Shanghai, 200080, China
    Dig Dis Sci 55:931-40. 2010
    ..Apparent hepatic perisinosodial fibrosis did not occur until week 24, and progressed from week 36 to 48 with insulin resistance. Therefore, this novel model may be potentially useful in NASH study...
  14. ncbi Effects of ursodeoxycholic acid and/or low-calorie diet on steatohepatitis in rats with obesity and hyperlipidemia
    Jian Gao Fan
    Department of Gastroenterology, Shanghai First People s Hospital, Shanghai 200080, China
    World J Gastroenterol 11:2346-50. 2005
    ..To evaluate the effects of ursodeoxycholic acid (UDCA) and/or low-calorie diet (LCD) on a rat model of nonalcoholic steatohepatitis (NASH)...
  15. ncbi Dynamic expression of hepatic thioredoxin mRNA in rats with non-alcoholic fatty liver disease
    Xiao Yan Duan
    Department of Gastroenterology, Shanghai First People s Hospital, Shanghai Jiaotong University, Shanghai, China
    J Dig Dis 11:94-100. 2010
    ..To investigate the expression and significance of thioredoxin messenger ribonucleic acid (mRNA) in the development of non-alcoholic fatty liver disease (NAFLD) induced by a high fat diet...
  16. ncbi Prevalence and risk factors of hepatic steatosis and its impact on liver injury in Chinese patients with chronic hepatitis B infection
    Jun ping Shi
    Center for Fatty Liver Disease, Shanghai First People s Hospital, Jiaotong University, Shanghai, China
    J Gastroenterol Hepatol 23:1419-25. 2008
    ..The aims of this study were thus to investigate the prevalence and risk factors for hepatic steatosis in patients with CHB and its relationship with liver injury...
  17. ncbi [Expression of uncoupling protein 2 and its relationship to the content of adenosine triphosphate in the nonalcoholic fatty livers of rats fed a high-fat diet]
    Jian Gao Fan
    Department of Gastroenterology, Shanghai First People s Hospital, Jiaotong University, Shanghai 200080, China
    Zhonghua Gan Zang Bing Za Zhi 13:374-7. 2005
    ..To investigate the expression of uncoupling protein 2 (UCP2) and its relationship to the content of adenosine triphosphate (ATP) in livers of nonalcoholic fatty liver disease (NAFLD) rats fed a fat-rich diet...
  18. ncbi Dyslipidemia in Shanghai, China
    Jia Yu Wu
    Department of Gastroenterology, Shanghai Xinhua Hospital, Center for Clinical Epidemiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Prev Med 51:412-5. 2010
    ..To determine the prevalence of and risk factors for dyslipidemia in Shanghai...
  19. ncbi Guidelines for the diagnosis and treatment of alcoholic liver disease
    Min De Zeng
    Shanghai Institute of Digestive Disease, Shanghai Jiaotong University School of Medicine, Shanghai, China
    J Dig Dis 9:113-6. 2008
  20. ncbi [A study of the changes of hepatic gene expression in the process of nonalcoholic fatty liver disease development using U230A oligonucleotide microarray]
    Jian Gao Fan
    Department of Digestive Diseases, Shanghai First People s Hospital, Jiaotong University, Shanghai 200080, China
    Zhonghua Gan Zang Bing Za Zhi 13:597-601. 2005
    ..To explore the changes of hepatic gene expression during the course of nonalcoholic fatty liver disease (NAFLD) development in rats...
  21. ncbi Effects of nonalcoholic fatty liver disease on the development of metabolic disorders
    Jian Gao Fan
    Center for Fatty Liver, Shanghai First People s Hospital, Jiaotong University, Shanghai, China
    J Gastroenterol Hepatol 22:1086-91. 2007
    ..However, the impact of NAFLD on metabolic syndrome is unclear. The aim of this study was to explore the influence of NAFLD on the development of metabolic disorders...
  22. ncbi Effectiveness of Danning Tablet in patients with non-alcoholic fatty liver of damp-heat syndrome type: a multicenter randomized controlled trial
    Guang Ji
    Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China
    Zhong Xi Yi Jie He Xue Bao 6:128-33. 2008
    ..To evaluate the efficacy and safety of Danning Tablet (DNT) in patients with non-alcoholic fatty liver disease (NAFLD) of damp-heat syndrome type...
  23. ncbi Evaluating the efficacy and safety of Danning Pian in the short-term treatment of patients with non-alcoholic fatty liver disease: a multicenter clinical trial
    Jian Gao Fan
    Department of Gastroenterology, Shanghai First People s Hospital, Shanghai Jiaotong University, Shanghai 200080, China
    Hepatobiliary Pancreat Dis Int 3:375-80. 2004
    ....
  24. ncbi [Current therapy strategies for nonalcoholic fatty liver disease]
    Ji Wei Fang
    Department of Gastroenterology, First People's Hospital Affiliated to Shanghai Communication University, Shanghai 200080, China
    Zhonghua Gan Zang Bing Za Zhi 11:120-2. 2003
  25. ncbi [Study on the prevailing trend of overweight and obesity in Shanghai Bao-Steel Company based population from 1995 to 2002]
    Feng Li
    Center for Fatty Liver, Shanghai First People s Hospital, Shanghai 200080, China
    Zhonghua Yu Fang Yi Xue Za Zhi 41:38-41. 2007
    ..To explore the change of the prevalence rates of overweight and obesity in Shanghai Bao-Steel Company population...
  26. ncbi Fatty liver reduces hepatitis B virus replication in a genotype B hepatitis B virus transgenic mice model
    Zheng Zhang
    Department of Gastroenterology, Shanghai Key Laboratory of Children s Digestion and Nutrition, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
    J Gastroenterol Hepatol 27:1858-64. 2012
    ..Therefore, the establishment and character of an animal model with both NAFLD and chronic HBV infection has become an urgent task...
  27. ncbi [Establishment and identification of non-alcoholic fatty liver disease in chronic hepatitis B virus infected mice]
    Zheng Zhang
    Department of Gastroenterology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China
    Zhonghua Gan Zang Bing Za Zhi 19:658-63. 2011
    ..To establish and identify an animal model of non-alcoholic fatty liver disease in chronic HBV infected mice...
  28. ncbi Commonly used animal models of non-alcoholic steatohepatitis
    Jian Gao Fan
    Department of Gastroenterology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
    Hepatobiliary Pancreat Dis Int 8:233-40. 2009
    ..Consequently, it is necessary to establish NASH models that can best mimic the real etiology, disease progression, and pathogenesis of human NASH...
  29. ncbi Effect of lactulose on establishment of a rat non-alcoholic steatohepatitis model
    Jian Gao Fan
    Department of Gastroenterology, Shanghai First People s Hospital, Jiaotong University, Shanghai 200080, China
    World J Gastroenterol 11:5053-6. 2005
    ..To explore the relationship between changes of intestinal environment and pathogenesis of non-alcoholic steatohepatitis (NASH)...
  30. ncbi Inhibition of high-mobility group box 1 expression by siRNA in rat hepatic stellate cells
    Wen Song Ge
    Department of Gastroenterology, Shanghai Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China
    World J Gastroenterol 17:4090-8. 2011
    ..To explore the role of high-mobility group box 1 (HMGB1) protein during liver fibrogenesis and investigate the functional effects of HMGB1 gene silencing in hepatic stellate cells (HSCs) using siRNA...
  31. ncbi Guidelines for the diagnosis and treatment of nonalcoholic fatty liver diseases
    Min De Zeng
    Shanghai Institute of Digestive Disease, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
    J Dig Dis 9:108-12. 2008
  32. ncbi [Classification and diagnostic strategies of nonalcoholic fatty liver diseases]
    Jian Gao Fan
    Center of Diagnosis and Treatment for Liver Diseases, First People's Hospital Affiliated to Shanghai Communication University, Shanghai 200080, China
    Zhonghua Gan Zang Bing Za Zhi 11:127-8. 2003
  33. ncbi Obesity, fatty liver and liver cancer
    Yan Qian
    Center for Fatty Liver Disease, First People's Hospital, Shanghai Jiaotong University, Shanghai 200080, China
    Hepatobiliary Pancreat Dis Int 4:173-7. 2005
    ..More frequent surveillance for HCC may be warranted in obese patients with fatty liver and attempts should be made to interrupt the progression from simple hepatic steatosis to steatohepatitis, cirrhosis and ultimately HCC...
  34. ncbi Suboptimal performance of simple noninvasive tests for advanced fibrosis in Chinese patients with nonalcoholic fatty liver disease
    Yun hao Xun
    Department of Infective Disease, Shanghai Sixth People s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, China
    J Dig Dis 13:588-95. 2012
    ..To evaluate the diagnostic accuracy of some noninvasive fibrosis models in Chinese patients with nonalcoholic fatty liver disease (NAFLD)...
  35. ncbi [An epidemiologic study on functional constipation among adult communities in Shanghai]
    Feng Shen
    Department of Gastroenterology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200092, China
    Zhonghua Liu Xing Bing Xue Za Zhi 33:296-300. 2012
    ..To determine the prevalence and risk factors of functional constipation (FC) by using Rome III criteria in the local adult communities...
  36. ncbi [Effect of silencing connective tissue growth factor on the liver fibrosis in rats]
    Guang ming Li
    Department of Gastroenterology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China
    Zhonghua Gan Zang Bing Za Zhi 18:822-5. 2010
    ....
  37. ncbi [Therapeutic strategies for nonalcoholic fatty liver disease]
    Jian Gao Fan
    First People's Hospital Affiliated to Shanghai Communication University, Shanghai 200080, China
    Zhonghua Gan Zang Bing Za Zhi 11:111. 2003
  38. ncbi Does non-alcoholic fatty liver disease predispose patients to type 2 diabetes in the absence of obesity?
    Jian Gao Fan
    J Gastroenterol Hepatol 25:223-5. 2010
  39. ncbi [Alcoholic and non-alcoholic fatty liver diseases]
    Jian-Gao Fan
    Department of Gastroenterology, Shanghai First People's Hospital, Jiaotong University, Shanghai 200080, China
    Zhonghua Gan Zang Bing Za Zhi 11:692. 2003
  40. ncbi [A report from the 2nd Symposium on Fatty Liver Diseases]
    Lun-Gen Lu
    Department of Gastroenterology, Renji Hospital, Shanghai Institute of Digestive Diseases, Shanghai Second Medical University, Shanghai 200001, China
    Zhonghua Gan Zang Bing Za Zhi 13:628-9. 2005
  41. ncbi Prevalence of nonalcoholic fatty liver among administrative officers in Shanghai: an epidemiological survey
    Lei Shen
    Department of Gastroenterology, Renji Hospital, Second Medical University, Shanghai, China
    World J Gastroenterol 9:1106-10. 2003
    ..CONCLUSION: There is a high prevalence of nonalcoholic fatty liver among certain population in Shanghai, to which overweight and hyperlipidemia are closely relevant...
  42. ncbi [Low dose of endotoxin induced acute liver failure in obese rats with nonalcoholic steatoheptitis]
    Zheng-Jie Xu
    Department of Gastroenterology, Shanghai First People's Hospital, Shanghai 200080, China
    Zhonghua Gan Zang Bing Za Zhi 12:244-5. 2004
  43. ncbi [Current therapy strategies for alcoholic hepatitis]
    Jian-Gao Fan
    Department of Gastroenterology, Shanghai First People's Hospital, Jiaotong University, Shanghai 200080, China
    Zhonghua Gan Zang Bing Za Zhi 11:703-4. 2003
  44. ncbi [Current strategy of prevention and treatment of obesity-related liver disease]
    Jian-Gao Fan
    Department of Digestive Disease, Shanghai First People's Hospital, Shanghai Jiaotong University, Shanghai 200080, China
    Zhonghua Gan Zang Bing Za Zhi 12:255-6. 2004
  45. ncbi [A case report of systemic lupus erythematous with severe steatohepatitis]
    Jian-Gao Fan
    Department of Gastroenterology, Shanghai First People's Hospital of Jiaotong University, Shanghai 200080, China
    Zhonghua Gan Zang Bing Za Zhi 12:337. 2004
  46. ncbi [Dynamic changes of plasma levels of prostacycline and thromboxane A2 and their correlation with the severity of hepatic injury in rats with nonalcoholic fatty liver disease.]
    Jian-Gao Fan
    Department of Gastroenterology, First People's Hospital, Shanghai Jiaotong University, Shanghai 200080, China
    Zhonghua Gan Zang Bing Za Zhi 12:681-3. 2004
    ..In this model, the imbalance of plasma PGI2 and TXA2 levels (increased TXB2 and decreased 6-keto-PGF1 alpha levels) may play a role in the pathogenesis of experimental NAFLD...
  47. ncbi [Current therapeutic strategy of fatty liver diseases]
    Jian-Gao Fan
    Center for Fatty Liver Research, Shanghai First People's Hospital of Transportation University, Shanghai 200080, China
    Zhonghua Gan Zang Bing Za Zhi 13:136-7. 2005
  48. ncbi [Diagnosis of non-alcoholic fatty liver diseases]
    Jian-Gao Fan
    Center for Fatty Liver Diseases, Shanghai First People's Hospital, Jiaotong University, Shanghai 200080, China
    Zhonghua Gan Zang Bing Za Zhi 13:710-1. 2005
  49. ncbi [Upregulating expressions of hepatic lipopolysaccharide receptors in nonalcoholic steatohepatitic rats]
    Zheng-Jie Xu
    Department of Gastroenterology, Shanghai First People's Hospital, Shanghai 200080, China
    Zhonghua Gan Zang Bing Za Zhi 14:49-52. 2006
    ..It may be one of the factors responsible for the increase of hepatic sensitivity to LPS injury of the NASH rats and may play an important role in the pathogenesis of NASH...
  50. ncbi VAT fat is bad for the liver, SAT fat is not!
    Jian-Gao Fan
    J Gastroenterol Hepatol 23:829-32. 2008
  51. ncbi [Clinical study on treatment of non-alcoholic fatty liver of damp-heat syndrome type by danning tablet]
    Guang Ji
    Department of Hepatology, Longhua Hospital, Shanghai University of TCM, Shanghai
    Zhongguo Zhong Xi Yi Jie He Za Zhi 25:485-8. 2005
    ..To evaluate the therapeutic effect of Danning Tablet (DNT) on patients with non-alcoholic fatty liver (NAFL) of damp-heat Syndrome type...
  52. ncbi Hepatitis B and fatty liver: causal or coincidental?
    Jian Gao Fan
    J Gastroenterol Hepatol 23:679-81. 2008