Research Topics
Genomes and Genes | Gehan A MostafaSummaryAffiliation: Faculty of Medicine Publications
| Collaborators
|
Detail Information
Publications
The link between some alleles on human leukocyte antigen system and autism in childrenGehan A Mostafa
Department of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt Autism Research and Treatment Center, AL Amodi Autism Research Chair, Department of Physiology, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia
J Neuroimmunol 255:70-4. 2013..This is important to determine whether therapeutic modulations of the immune function are legitimate avenues for novel therapy in selected cases of autism...- The relationship between the increased frequency of serum antineuronal antibodies and the severity of autism in childrenGehan Ahmed Mostafa
Autism Research and Treatment Center, AL Amodi Autism Research Chair, Department of Physiology, King Saud University, Riyadh, Saudi Arabia
Eur J Paediatr Neurol 16:464-8. 2012..Autism may involve an autoimmune pathogenesis. Immunotherapy may have a role in autistic children who have brain auto-antibodies... 
Reduced serum concentrations of 25-hydroxy vitamin D in children with autism: relation to autoimmunityGehan A Mostafa
Autism Research and Treatment Center, AL Amodi Autism Research Chair, Department of Physiology, King Saud University, Riyadh, Saudi Arabia
J Neuroinflammation 9:201. 2012..We are the first to investigate the relationship between serum levels of 25-hydroxy vitamin D and anti-myelin-associated glycoprotein (anti-MAG) auto-antibodies in autistic children...- Elevated serum levels of interleukin-17A in children with autismLaila Yousef Al-Ayadhi
Department of Physiology, Autism Research and Treatment Center, AL Amodi Autism Research Chair, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia
J Neuroinflammation 9:158. 2012..The aim of this study was to measure serum levels of IL-17A in relation to the degree of the severity of autism... - A lack of association between elevated serum levels of S100B protein and autoimmunity in autistic childrenLaila Yousef Al-Ayadhi
Autism Research and Treatment Center, AL Amodi Autism Research Chair, Department of Physiology, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia
J Neuroinflammation 9:54. 2012..We are the first to investigate the relationship between serum levels of S100B protein, a marker of neuronal damage, and antiribosomal P protein antibodies in autistic children... - The role of measurement of serum autoantibodies in prediction of pediatric neuropsychiatric systemic lupus erythematosusGehan A Mostafa
Department of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt
J Neuroimmunol 227:195-201. 2010..Thus, they may be reliable parameters for early diagnosis and management of NPSLE before clinical manifestations ensue. In addition, anti-ganglioside M1 antibodies may play a role in cognitive dysfunction found in some lupus patients... - The link of C4B null allele to autism and to a family history of autoimmunity in Egyptian autistic childrenGehan A Mostafa
Department of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt
J Neuroimmunol 223:115-9. 2010..5-67.8). Conclusions: the link of C4B null allele to autism and to a family history of autoimmunity may indicate its possible contributing role to autoimmunity in autism... - Oxidative stress in Egyptian children with autism: relation to autoimmunityGehan A Mostafa
Department of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt
J Neuroimmunol 219:114-8. 2010..Therefore, studies considering the role of antioxidants and immunotherapy in amelioration of autistic manifestations are recommended... - Frequency of CD4+CD25high regulatory T cells in the peripheral blood of Egyptian children with autismGehan A Mostafa
Department of Pediatrics, Faculty of Medicine, Ain Shams University, Nasr City, Cairo, Egypt
J Child Neurol 25:328-35. 2010..Deficiency of these cells may contribute to autoimmunity in a subgroup of children with autism. Consequently, CD4(+)CD25(high) regulatory T cells could be new potential therapeutic targets in these patients... - Blood lead levels in Egyptian children from high and low lead-polluted areas: impact on cognitive functionG A Mostafa
Department of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt
Acta Neurol Scand 120:30-7. 2009..Many children are harmed by low-level lead exposure which impairs cognitive development with subsequent poor scholastic achievement. We investigated blood lead levels in children in relation to cognitive function... - Serum anti-nuclear antibodies as a marker of autoimmunity in Egyptian autistic childrenGehan A Mostafa
Department of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt
Pediatr Neurol 40:107-12. 2009..Further studies are warranted to assess anti-nuclear antibody seropositivity, other markers of autoimmunity (e.g., brain-specific autoantibodies), and the role of immunotherapy in children with autism... - Serum anti-myelin-associated glycoprotein antibodies in Egyptian autistic childrenGehan Ahmed Mostafa
Department of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt
J Child Neurol 23:1413-8. 2008..Further studies are warranted to shed light on the etiopathogenic role of anti-myelin-associated glycoprotein antibodies and the role of immunotherapy in autism... - The possible link between the elevated serum levels of neurokinin A and anti-ribosomal P protein antibodies in children with autismGehan A Mostafa
Autism Research and Treatment Center, AL Amodi Autism Research Chair, Department of Physiology, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia
J Neuroinflammation 8:180. 2011..We are the first to measure serum neurokinin A levels in autistic children. The relationship between serum levels of neurokinin A and anti-ribosomal P protein antibodies was also studied... - A lack of association between hyperserotonemia and the increased frequency of serum anti-myelin basic protein auto-antibodies in autistic childrenGehan Ahmed Mostafa
Autism Research and Treatment Center, AL Amodi Autism Research Chair, Department of Physiology, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia
J Neuroinflammation 8:71. 2011..We are the first to investigate the possible role of hyperserotonemia in the induction of autoimmunity, as indicated by serum anti-myelin-basic protein (anti-MBP) auto-antibodies, in autism... - Increased serum levels of anti-ganglioside M1 auto-antibodies in autistic children: relation to the disease severityGehan A Mostafa
Autism Research and Treatment Center, Department of Physiology, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia
J Neuroinflammation 8:39. 2011..We are the first to measure the relationship between these antibodies and the degree of the severity of autism... - Antineuronal antibodies and electroneurophysiological studies in pediatric patients with neuropsychiatric systemic lupus erythematosusGehan A Mostafa
Department of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt
Pediatr Allergy Immunol 20:192-9. 2009..Further studies on a large scale are warranted to evaluate the predictive value of these parameters in NPSLE... - Increased serum osteopontin levels in autistic children: relation to the disease severityLaila Y Al-Ayadhi
Autism Research and Treatment Center, AL Amodi Autism Research Chair, Department of Physiology, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia
Brain Behav Immun 25:1393-8. 2011..The therapeutic role of anti-osteopontin antibodies in amelioration of autistic manifestations should also be studied... - Low plasma progranulin levels in children with autismLaila Y Al-Ayadhi
Autism Research and Treatment Center, AL Amodi Autism Research Chair, Department of Physiology, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia
J Neuroinflammation 8:111. 2011..We are the first to measure plasma progranulin levels in autism... - Cardiovascular autonomic function assessed by autonomic function tests and serum autonomic neuropeptides in Egyptian children and adolescents with rheumatic diseasesZeinab A El-Sayed
Department of Paediatrics, Faculty of Medicine, Institute of Postgraduate Childhood Studies, Ain Shams University, Cairo, Egypt
Rheumatology (Oxford) 48:843-8. 2009..Autonomic dysfunction may contribute to initiation and perpetuation of rheumatic diseases. Thus, we aimed to assess cardiovascular autonomic function in lupus and juvenile idiopathic arthritis (JIA) patients... - Autoantibody to heterogeneous nuclear ribonucleoprotein-A2 (RA33) in juvenile idiopathic arthritis: clinical significanceHoda Y Tomoum
Department of Pediatrics, Faculty of Medicaine, Ain Shams University, Cairo, Egypt
Pediatr Int 51:188-92. 2009..The aim of the present study was therefore to investigate the value of anti-RA33 for diagnosis of JIA (both early and established disease), and its relation to markers of disease activity, and bone resorption...