J A L Ives

Summary

Affiliation: F. Hoffmann-La Roche Ltd

Publications

  1. ncbi request reprint The H274Y mutation in the influenza A/H1N1 neuraminidase active site following oseltamivir phosphate treatment leave virus severely compromised both in vitro and in vivo
    J A L Ives
    Roche Products Ltd, 40 Broadwater Road, Welwyn Garden City, AL7 3AY, Hertfordshire, UK
    Antiviral Res 55:307-17. 2002

Detail Information

Publications1

  1. ncbi request reprint The H274Y mutation in the influenza A/H1N1 neuraminidase active site following oseltamivir phosphate treatment leave virus severely compromised both in vitro and in vivo
    J A L Ives
    Roche Products Ltd, 40 Broadwater Road, Welwyn Garden City, AL7 3AY, Hertfordshire, UK
    Antiviral Res 55:307-17. 2002
    ..Additionally, pathogenicity of the mutant virus is significantly compromised in ferret, compared to the corresponding wild type virus. Virus carrying a H274Y mutation is unlikely to be of clinical consequence in man...