A Choppin

Summary

Affiliation: F. Hoffmann-La Roche Ltd

Publications

  1. pmc Characterization of the muscarinic receptor in isolated uterus of sham operated and ovariectomized rats
    A Choppin
    Center for Biological Research, Neurobiology Unit, Roche Bioscience, R2 101, 3401 Hillview Avenue, Palo Alto, California 94304, USA
    Br J Pharmacol 127:1551-8. 1999
  2. pmc Pharmacological characterization of muscarinic receptors in dog isolated ciliary and urinary bladder smooth muscle
    A Choppin
    Genitourinary Pharmacology, Neurobiology Unit, Roche Bioscience, Palo Alto, California, CA 94304, USA
    Br J Pharmacol 132:835-42. 2001
  3. ncbi request reprint Evaluation of oral ro70-0004/003, an alpha1A-adrenoceptor antagonist, in the treatment of male erectile dysfunction
    A Choppin
    Genitourinary Systems, Neurobiology Unit, Roche Bioscience, Palo Alto, California 94304, USA
    Int J Impot Res 13:157-61. 2001
  4. pmc Pharmacological characterization of muscarinic receptors in mouse isolated urinary bladder smooth muscle
    A Choppin
    Genitourinary Pharmacology, Neurobiology Unit, Roche Bioscience, Palo Alto, California, CA 94304, U S A
    Br J Pharmacol 133:1035-40. 2001
  5. ncbi request reprint Muscarinic receptor ligands and their therapeutic potential
    R M Eglen
    Center for Biological Research, Roche Bioscience, Palo Alto, CA 94304, USA
    Curr Opin Chem Biol 3:426-32. 1999
  6. pmc Muscarinic receptors in isolated urinary bladder smooth muscle from different mouse strains
    A Choppin
    Genitourinary Pharmacology, Deltagen, Inc, Menlo Park, California, CA 94025, USA
    Br J Pharmacol 137:522-8. 2002

Detail Information

Publications6

  1. pmc Characterization of the muscarinic receptor in isolated uterus of sham operated and ovariectomized rats
    A Choppin
    Center for Biological Research, Neurobiology Unit, Roche Bioscience, R2 101, 3401 Hillview Avenue, Palo Alto, California 94304, USA
    Br J Pharmacol 127:1551-8. 1999
    ..These data further suggest that the pharmacological profile and proportions of the two populations of muscarinic receptors are unaffected by ovariectomy...
  2. pmc Pharmacological characterization of muscarinic receptors in dog isolated ciliary and urinary bladder smooth muscle
    A Choppin
    Genitourinary Pharmacology, Neurobiology Unit, Roche Bioscience, Palo Alto, California, CA 94304, USA
    Br J Pharmacol 132:835-42. 2001
    ....
  3. ncbi request reprint Evaluation of oral ro70-0004/003, an alpha1A-adrenoceptor antagonist, in the treatment of male erectile dysfunction
    A Choppin
    Genitourinary Systems, Neurobiology Unit, Roche Bioscience, Palo Alto, California 94304, USA
    Int J Impot Res 13:157-61. 2001
    ..The highly selective alpha1A-adrenoceptor antagonist, Ro70-0004, given at a single dose of 5 mg, did not improve erectile function when compared to placebo...
  4. pmc Pharmacological characterization of muscarinic receptors in mouse isolated urinary bladder smooth muscle
    A Choppin
    Genitourinary Pharmacology, Neurobiology Unit, Roche Bioscience, Palo Alto, California, CA 94304, U S A
    Br J Pharmacol 133:1035-40. 2001
    ..16+/-0.03). Overall, these data study suggest that muscarinic M(3) receptors are the predominant, if not the exclusive, subtype mediating contractile responses to muscarinic agonists in male mouse urinary bladder smooth muscle...
  5. ncbi request reprint Muscarinic receptor ligands and their therapeutic potential
    R M Eglen
    Center for Biological Research, Roche Bioscience, Palo Alto, CA 94304, USA
    Curr Opin Chem Biol 3:426-32. 1999
    ....
  6. pmc Muscarinic receptors in isolated urinary bladder smooth muscle from different mouse strains
    A Choppin
    Genitourinary Pharmacology, Deltagen, Inc, Menlo Park, California, CA 94025, USA
    Br J Pharmacol 137:522-8. 2002
    ..4. These data study suggest that muscarinic M(3) receptors are the predominant, if not the exclusive, subtype mediating contractile responses to muscarinic agonists in female mouse urinary bladder smooth muscle, with strain differences...