Affiliation: F. Hoffmann-La Roche Ltd
- 5-Hydroxytryptamine1B receptor-mediated contraction of rabbit saphenous vein and basilar artery: role of vascular endotheliumAnindya Bhattacharya
Lilly Research Laboratories, Eli Lilly and Co, Indianapolis, Indiana, USA
J Pharmacol Exp Ther 309:825-32. 2004....
- Amplification of sumatriptan-induced contraction in rabbit saphenous vein but not in basilar arteryAnindya Bhattacharya
Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana 46285, USA
Am J Physiol Heart Circ Physiol 284:H719-26. 2003..These data suggest that in the in vivo plasma milieu sumatriptan will more markedly contract the peripheral saphenous vein than the basilar artery, a cerebral blood vessel...
- Lack of sumatriptan-induced aortic contraction or relaxation: 5-HT1B receptor protein detected in endothelium and smooth muscle of vasa vasorum but not aortaMarlene L Cohen
Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285, USA
Receptors Channels 8:71-8. 2002..Furthermore, caution must be observed when using 5-HT1B receptor mRNA to suggest receptor protein in tissues since this RT-PCR product may be derived predominantly from small blood vessels...
- Pharmacology and antitussive efficacy of 4-(3-trifluoromethyl-pyridin-2-yl)-piperazine-1-carboxylic acid (5-trifluoromethyl-pyridin-2-yl)-amide (JNJ17203212), a transient receptor potential vanilloid 1 antagonist in guinea pigsAnindya Bhattacharya
Department of Pain and Related Disorders, Johnson and Johnson Pharmaceutical Research and Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, USA
J Pharmacol Exp Ther 323:665-74. 2007..Last, JNJ17203212 dose-dependently produced antitussive efficacy in citric acid-induced experimental cough in guinea pigs. Our data provide preclinical support for developing TRPV1 antagonists for the treatment of cough...