Research Topics
| Jessica PontiSummaryAffiliation: European Commission Publications
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Detail Information
Publications
Morphological transformation induced by multiwall carbon nanotubes on Balb/3T3 cell model as an in vitro end point of carcinogenic potentialJessica Ponti
European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Nanobiosciences Unit, Ispra, VA, Italy
Nanotoxicology 7:221-33. 2013....
Colony Forming Efficiency and microscopy analysis of multi-wall carbon nanotubes cell interactionJessica Ponti
European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Nanobiosciences Unit, 21027 Ispra, VA, Italy
Toxicol Lett 197:29-37. 2010....
Problems and challenges in the development and validation of human cell-based assays to determine nanoparticle-induced immunomodulatory effectsGertie J Oostingh
Department of Molecular Biology, University of Salzburg, 5020 Salzburg, Austria
Part Fibre Toxicol 8:8. 2011..However, before assays can be standardised, it is important that suitable methods are established and validated...
Online monitoring of cell metabolism to assess the toxicity of nanoparticles: the case of cobalt ferriteValentina Mariani
European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Nanobiosciences Unit, Ispra Va, Italy
Nanotoxicology 6:272-87. 2012..In conclusion, this work demonstrated that the measurement of metabolic parameters with a microphysiometer is a promising method to assess the toxicity of NPs and offers the advantage to follow on-line the cell metabolic changes...
Assessment of cytotoxicity by impedance spectroscopyLaura Ceriotti
European Commission, Joint Research Centre, Institute for Health and Consumer Protection, TP 203, via E Fermi 1, 21020 Ispra, VA, Italy
Biosens Bioelectron 22:3057-63. 2007..In term of impedance signal, the modulus results was found to be the most sensitive of the considered components for cytotoxicity testing of chemicals...
Genotoxicity and morphological transformation induced by cobalt nanoparticles and cobalt chloride: an in vitro study in Balb/3T3 mouse fibroblastsJessica Ponti
Nanobiosciences Unit, European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Via E Fermi 2749, 21027 Ispra VA, Italy
Mutagenesis 24:439-45. 2009..Furthermore, we observed a higher cellular uptake of Co-nano compared with Co(2+)...
Amorphous silica nanoparticles do not induce cytotoxicity, cell transformation or genotoxicity in Balb/3T3 mouse fibroblastsChiara Uboldi
European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Nanobiosciences Unit, TP203, Via E Fermi 2749, 21027, Ispra Va, Italy
Mutat Res 745:11-20. 2012....
Size-dependent toxicity and cell interaction mechanisms of gold nanoparticles on mouse fibroblastsRosella Coradeghini
Nanobiosciences Unit, Joint Research Centre, Institute for Health and Consumer Protection, European Commission, Via E Fermi 2749, 21027 Ispra, VA, Italy
Toxicol Lett 217:205-16. 2013..No significant effect was observed in the expression level of caveolin, while reduction of the expression and degradation of the clathrin heavy chain was observed in cells exposed for 72 h to AuNPs...
Cellular distribution and degradation of cobalt ferrite nanoparticles in Balb/3T3 mouse fibroblastsPatrick Marmorato
European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Ispra Va, Italy
Toxicol Lett 207:128-36. 2011....
Development of a mechanistically-based genetically engineered PC12 cell system to detect p53-mediated cytotoxicityErwin van Vliet
European Centre for the Validation of Alternative Methods ECVAM, Institute for Health and Consumer Protection, European Commission Joint Research Centre, via E Fermi 1, 21020 Ispra VA, Italy
Toxicol In Vitro 21:698-705. 2007....
Comparison of impedance-based sensors for cell adhesion monitoring and in vitro methods for detecting cytotoxicity induced by chemicalsJessica Ponti
Joint Research Centre, BMS Unit, TP580, via E Fermi 1, 21020 Ispra, VA, Italy
Altern Lab Anim 34:515-25. 2006..The results show that the sensitivity of the developed chip was better than that with the MTT test, with the additional advantages of online monitoring...
