Jessica Ponti

Summary

Affiliation: European Commission

Publications

  1. pmc Predictive toxicology of cobalt ferrite nanoparticles: comparative in-vitro study of different cellular models using methods of knowledge discovery from data
    Limor Horev-Azaria
    Department of Physiology and Pharmacology, Faculty of Medicine and the Marian Gertner Institute for Medical Nanosystems, Tel Aviv University, Tel Aviv 69978, Israel
    Part Fibre Toxicol 10:32. 2013
  2. doi Morphological transformation induced by multiwall carbon nanotubes on Balb/3T3 cell model as an in vitro end point of carcinogenic potential
    Jessica Ponti
    European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Nanobiosciences Unit, Ispra, VA, Italy
    Nanotoxicology 7:221-33. 2013
  3. doi Colony Forming Efficiency and microscopy analysis of multi-wall carbon nanotubes cell interaction
    Jessica Ponti
    European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Nanobiosciences Unit, 21027 Ispra, VA, Italy
    Toxicol Lett 197:29-37. 2010
  4. pmc Problems and challenges in the development and validation of human cell-based assays to determine nanoparticle-induced immunomodulatory effects
    Gertie J Oostingh
    Department of Molecular Biology, University of Salzburg, 5020 Salzburg, Austria
    Part Fibre Toxicol 8:8. 2011
  5. doi Online monitoring of cell metabolism to assess the toxicity of nanoparticles: the case of cobalt ferrite
    Valentina Mariani
    European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Nanobiosciences Unit, Ispra Va, Italy
    Nanotoxicology 6:272-87. 2012
  6. ncbi Assessment of cytotoxicity by impedance spectroscopy
    Laura Ceriotti
    European Commission, Joint Research Centre, Institute for Health and Consumer Protection, TP 203, via E Fermi 1, 21020 Ispra, VA, Italy
    Biosens Bioelectron 22:3057-63. 2007
  7. doi Genotoxicity and morphological transformation induced by cobalt nanoparticles and cobalt chloride: an in vitro study in Balb/3T3 mouse fibroblasts
    Jessica Ponti
    Nanobiosciences Unit, European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Via E Fermi 2749, 21027 Ispra VA, Italy
    Mutagenesis 24:439-45. 2009
  8. doi Mechanisms of toxicity induced by SiO2 nanoparticles of in vitro human alveolar barrier: effects on cytokine production, oxidative stress induction, surfactant proteins A mRNA expression and nanoparticles uptake
    Lucian Romeo Farcal
    Institute for Health and Consumer Protection, Joint Research Centre, European Commission, Validation of Alternative Methods Unit EURL ECVAM, Via E Fermi 2749, Ispra Va, Italy
    Nanotoxicology 7:1095-110. 2013
  9. doi Size-dependent toxicity and cell interaction mechanisms of gold nanoparticles on mouse fibroblasts
    Rosella Coradeghini
    Nanobiosciences Unit, Joint Research Centre, Institute for Health and Consumer Protection, European Commission, Via E Fermi 2749, 21027 Ispra, VA, Italy
    Toxicol Lett 217:205-16. 2013
  10. doi Amorphous silica nanoparticles do not induce cytotoxicity, cell transformation or genotoxicity in Balb/3T3 mouse fibroblasts
    Chiara Uboldi
    European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Nanobiosciences Unit, TP203, Via E Fermi 2749, 21027, Ispra Va, Italy
    Mutat Res 745:11-20. 2012

Collaborators

  • Hubert Rauscher
  • Pascal Colpo
  • Thomas Hartung
  • Winfried Steiling
  • Emanuela Testai
  • Silvia Casati
  • Alessandra Gennari
  • Susanne Bremer
  • Magnus Ingelman-Sundberg
  • Raffaella Corvi
  • Andre Guillouzo
  • Bas J Blaauboer
  • Lorella Pascolo
  • Pilar Prieto
  • Erwin van Vliet
  • Francois Rossi
  • Chiara Uboldi
  • Douglas Gilliland
  • Guido Giudetti
  • Patrick Marmorato
  • Limor Horev-Azaria
  • Rosella Coradeghini
  • Paola Nativo
  • Lucian Romeo Farcal
  • Enrico Sabbioni
  • Fabio Franchini
  • Sabrina Gioria
  • Francesca Broggi
  • Valentina Mariani
  • Gertie J Oostingh
  • Laura Ceriotti
  • Sandra Coecke
  • Francesca Mazzotti
  • Ronald E Unger
  • Ute Golla-Schindler
  • Cesar Pascual Garcia
  • Dora Mehn
  • Patrice N Marche
  • Daniel Bonacchi
  • Dieter Sommer
  • James C Kirkpatrick
  • Anna Bal-Price
  • Delila Beno
  • Roni Romano
  • Rafi Korenstein
  • Christian Villiers
  • Susanne Kolle
  • Giovanni Baldi
  • Robert Landsiedel
  • Oded Maimon
  • Eudald Casals
  • Murielle Salomé
  • Renato Colognato
  • René Stritzinger
  • Maya Kiskinova
  • Flavia Favilli
  • Hagen Thielecke
  • Albert Duschl
  • Hilde Leppens
  • Burkhard Kaulich
  • Davide Lucchesi
  • Diana Boraschi
  • Yvonne Kohl
  • Daniella Ooms
  • Tobias Pfaller
  • Giacomo Ceccone
  • Victor F Puntes
  • Inge Nelissen
  • Paola Italiani
  • Alessandra Gianoncelli
  • Jean Francois Ghersi-Egea
  • Siegfried Morath
  • Sharon Munn
  • Hans Ahr
  • Lysianne Richert
  • Michael L Cunningham
  • Jose Castell
  • Brighitta Eletti
  • Bernhard Ladstetter
  • Annarita Meneguz
  • Beatrice Schaack
  • David Leahy
  • Greetje Elaut
  • Peter Hoet
  • Olavi Pelkonen
  • Anthony Long
  • Robert Combes
  • Charles L Crespi
  • Joan Albert Vericat
  • Andrew Worth

Detail Information

Publications15

  1. pmc Predictive toxicology of cobalt ferrite nanoparticles: comparative in-vitro study of different cellular models using methods of knowledge discovery from data
    Limor Horev-Azaria
    Department of Physiology and Pharmacology, Faculty of Medicine and the Marian Gertner Institute for Medical Nanosystems, Tel Aviv University, Tel Aviv 69978, Israel
    Part Fibre Toxicol 10:32. 2013
    ..Cobalt-ferrite nanoparticles (Co-Fe NPs) are attractive for nanotechnology-based therapies. Thus, exploring their effect on viability of seven different cell lines representing different organs of the human body is highly important...
  2. doi Morphological transformation induced by multiwall carbon nanotubes on Balb/3T3 cell model as an in vitro end point of carcinogenic potential
    Jessica Ponti
    European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Nanobiosciences Unit, Ispra, VA, Italy
    Nanotoxicology 7:221-33. 2013
    ....
  3. doi Colony Forming Efficiency and microscopy analysis of multi-wall carbon nanotubes cell interaction
    Jessica Ponti
    European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Nanobiosciences Unit, 21027 Ispra, VA, Italy
    Toxicol Lett 197:29-37. 2010
    ....
  4. pmc Problems and challenges in the development and validation of human cell-based assays to determine nanoparticle-induced immunomodulatory effects
    Gertie J Oostingh
    Department of Molecular Biology, University of Salzburg, 5020 Salzburg, Austria
    Part Fibre Toxicol 8:8. 2011
    ..However, before assays can be standardised, it is important that suitable methods are established and validated...
  5. doi Online monitoring of cell metabolism to assess the toxicity of nanoparticles: the case of cobalt ferrite
    Valentina Mariani
    European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Nanobiosciences Unit, Ispra Va, Italy
    Nanotoxicology 6:272-87. 2012
    ..In conclusion, this work demonstrated that the measurement of metabolic parameters with a microphysiometer is a promising method to assess the toxicity of NPs and offers the advantage to follow on-line the cell metabolic changes...
  6. ncbi Assessment of cytotoxicity by impedance spectroscopy
    Laura Ceriotti
    European Commission, Joint Research Centre, Institute for Health and Consumer Protection, TP 203, via E Fermi 1, 21020 Ispra, VA, Italy
    Biosens Bioelectron 22:3057-63. 2007
    ..In term of impedance signal, the modulus results was found to be the most sensitive of the considered components for cytotoxicity testing of chemicals...
  7. doi Genotoxicity and morphological transformation induced by cobalt nanoparticles and cobalt chloride: an in vitro study in Balb/3T3 mouse fibroblasts
    Jessica Ponti
    Nanobiosciences Unit, European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Via E Fermi 2749, 21027 Ispra VA, Italy
    Mutagenesis 24:439-45. 2009
    ..Furthermore, we observed a higher cellular uptake of Co-nano compared with Co(2+)...
  8. doi Mechanisms of toxicity induced by SiO2 nanoparticles of in vitro human alveolar barrier: effects on cytokine production, oxidative stress induction, surfactant proteins A mRNA expression and nanoparticles uptake
    Lucian Romeo Farcal
    Institute for Health and Consumer Protection, Joint Research Centre, European Commission, Validation of Alternative Methods Unit EURL ECVAM, Via E Fermi 2749, Ispra Va, Italy
    Nanotoxicology 7:1095-110. 2013
    ..The obtained results suggested that in vitro approach can be used to study pulmonary toxicity as long as the applied in vitro model mimics closely the complexity of in vivo situation...
  9. doi Size-dependent toxicity and cell interaction mechanisms of gold nanoparticles on mouse fibroblasts
    Rosella Coradeghini
    Nanobiosciences Unit, Joint Research Centre, Institute for Health and Consumer Protection, European Commission, Via E Fermi 2749, 21027 Ispra, VA, Italy
    Toxicol Lett 217:205-16. 2013
    ..No significant effect was observed in the expression level of caveolin, while reduction of the expression and degradation of the clathrin heavy chain was observed in cells exposed for 72 h to AuNPs...
  10. doi Amorphous silica nanoparticles do not induce cytotoxicity, cell transformation or genotoxicity in Balb/3T3 mouse fibroblasts
    Chiara Uboldi
    European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Nanobiosciences Unit, TP203, Via E Fermi 2749, 21027, Ispra Va, Italy
    Mutat Res 745:11-20. 2012
    ....
  11. ncbi Development of a mechanistically-based genetically engineered PC12 cell system to detect p53-mediated cytotoxicity
    Erwin van Vliet
    European Centre for the Validation of Alternative Methods ECVAM, Institute for Health and Consumer Protection, European Commission Joint Research Centre, via E Fermi 1, 21020 Ispra VA, Italy
    Toxicol In Vitro 21:698-705. 2007
    ....
  12. ncbi Comparison of impedance-based sensors for cell adhesion monitoring and in vitro methods for detecting cytotoxicity induced by chemicals
    Jessica Ponti
    Joint Research Centre, BMS Unit, TP580, via E Fermi 1, 21020 Ispra, VA, Italy
    Altern Lab Anim 34:515-25. 2006
    ..The results show that the sensitivity of the developed chip was better than that with the MTT test, with the additional advantages of online monitoring...
  13. doi Cellular distribution and degradation of cobalt ferrite nanoparticles in Balb/3T3 mouse fibroblasts
    Patrick Marmorato
    European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Ispra Va, Italy
    Toxicol Lett 207:128-36. 2011
    ....
  14. ncbi Metabolism: a bottleneck in in vitro toxicological test development. The report and recommendations of ECVAM workshop 54
    Sandra Coecke
    ECVAM, Institute for Health and Consumer Protection, European Commission Joint Research Centre, Ispra, Italy
    Altern Lab Anim 34:49-84. 2006
  15. ncbi In vitro setting of dose-effect relationships of 32 metal compounds in the Balb/3T3 cell line, as a basis for predicting their carcinogenic potential
    Francesca Mazzotti
    ECVAM, Institute for Health and Consumer Protection, European Commission Joint Research Centre, 21020 Ispra, VA, Italy
    Altern Lab Anim 30:209-17. 2002
    ....