Jessica Ponti

Summary

Affiliation: European Commission

Publications

  1. pmc Predictive toxicology of cobalt ferrite nanoparticles: comparative in-vitro study of different cellular models using methods of knowledge discovery from data
    Limor Horev-Azaria
    Department of Physiology and Pharmacology, Faculty of Medicine and the Marian Gertner Institute for Medical Nanosystems, Tel Aviv University, Tel Aviv 69978, Israel
    Part Fibre Toxicol 10:32. 2013
  2. doi request reprint Morphological transformation induced by multiwall carbon nanotubes on Balb/3T3 cell model as an in vitro end point of carcinogenic potential
    Jessica Ponti
    European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Nanobiosciences Unit, Ispra, VA, Italy
    Nanotoxicology 7:221-33. 2013
  3. doi request reprint Colony Forming Efficiency and microscopy analysis of multi-wall carbon nanotubes cell interaction
    Jessica Ponti
    European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Nanobiosciences Unit, 21027 Ispra, VA, Italy
    Toxicol Lett 197:29-37. 2010
  4. pmc Problems and challenges in the development and validation of human cell-based assays to determine nanoparticle-induced immunomodulatory effects
    Gertie J Oostingh
    Department of Molecular Biology, University of Salzburg, 5020 Salzburg, Austria
    Part Fibre Toxicol 8:8. 2011
  5. doi request reprint Online monitoring of cell metabolism to assess the toxicity of nanoparticles: the case of cobalt ferrite
    Valentina Mariani
    European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Nanobiosciences Unit, Ispra Va, Italy
    Nanotoxicology 6:272-87. 2012
  6. ncbi request reprint Assessment of cytotoxicity by impedance spectroscopy
    Laura Ceriotti
    European Commission, Joint Research Centre, Institute for Health and Consumer Protection, TP 203, via E Fermi 1, 21020 Ispra, VA, Italy
    Biosens Bioelectron 22:3057-63. 2007
  7. doi request reprint Genotoxicity and morphological transformation induced by cobalt nanoparticles and cobalt chloride: an in vitro study in Balb/3T3 mouse fibroblasts
    Jessica Ponti
    Nanobiosciences Unit, European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Via E Fermi 2749, 21027 Ispra VA, Italy
    Mutagenesis 24:439-45. 2009
  8. doi request reprint Mechanisms of toxicity induced by SiO2 nanoparticles of in vitro human alveolar barrier: effects on cytokine production, oxidative stress induction, surfactant proteins A mRNA expression and nanoparticles uptake
    Lucian Romeo Farcal
    Institute for Health and Consumer Protection, Joint Research Centre, European Commission, Validation of Alternative Methods Unit EURL ECVAM, Via E Fermi 2749, Ispra Va, Italy
    Nanotoxicology 7:1095-110. 2013
  9. ncbi request reprint Size-dependent toxicity and cell interaction mechanisms of gold nanoparticles on mouse fibroblasts
    Rosella Coradeghini
    Nanobiosciences Unit, Joint Research Centre, Institute for Health and Consumer Protection, European Commission, Via E Fermi 2749, 21027 Ispra, VA, Italy
    Toxicol Lett 217:205-16. 2013
  10. doi request reprint Amorphous silica nanoparticles do not induce cytotoxicity, cell transformation or genotoxicity in Balb/3T3 mouse fibroblasts
    Chiara Uboldi
    European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Nanobiosciences Unit, TP203, Via E Fermi 2749, 21027, Ispra Va, Italy
    Mutat Res 745:11-20. 2012

Collaborators

  • Hubert Rauscher
  • Pascal Colpo
  • Thomas Hartung
  • Winfried Steiling
  • Emanuela Testai
  • Silvia Casati
  • Alessandra Gennari
  • Susanne Bremer
  • Magnus Ingelman-Sundberg
  • Raffaella Corvi
  • Andre Guillouzo
  • Bas J Blaauboer
  • Pilar Prieto
  • Lorella Pascolo
  • Erwin van Vliet
  • Francois Rossi
  • Chiara Uboldi
  • Douglas Gilliland
  • Guido Giudetti
  • Patrick Marmorato
  • Rosella Coradeghini
  • Limor Horev-Azaria
  • Paola Nativo
  • Lucian Romeo Farcal
  • Sabrina Gioria
  • Fabio Franchini
  • Enrico Sabbioni
  • Francesca Broggi
  • Valentina Mariani
  • Gertie J Oostingh
  • Laura Ceriotti
  • Sandra Coecke
  • Francesca Mazzotti
  • Delila Beno
  • Cesar Pascual Garcia
  • Dora Mehn
  • Robert Landsiedel
  • Roni Romano
  • Christian Villiers
  • Giovanni Baldi
  • Oded Maimon
  • Ute Golla-Schindler
  • Anna Bal-Price
  • Patrice N Marche
  • Ronald E Unger
  • Rafi Korenstein
  • Dieter Sommer
  • Daniel Bonacchi
  • James C Kirkpatrick
  • Susanne Kolle
  • Tobias Pfaller
  • Alessandra Gianoncelli
  • René Stritzinger
  • Yvonne Kohl
  • Flavia Favilli
  • Paola Italiani
  • Davide Lucchesi
  • Hilde Leppens
  • Daniella Ooms
  • Inge Nelissen
  • Renato Colognato
  • Hagen Thielecke
  • Burkhard Kaulich
  • Eudald Casals
  • Giacomo Ceccone
  • Victor F Puntes
  • Murielle Salomé
  • Diana Boraschi
  • Albert Duschl
  • Maya Kiskinova
  • Beatrice Schaack
  • Peter Hoet
  • Andrew Worth
  • Joan Albert Vericat
  • Michael L Cunningham
  • Annarita Meneguz
  • Fred Nagelkerke
  • Olavi Pelkonen
  • Anthony Long
  • Lysianne Richert
  • Charles L Crespi
  • Brighitta Eletti
  • Sharon Munn
  • Robert Combes
  • Jose Castell
  • Bernhard Ladstetter
  • Greetje Elaut
  • Mario Monshouwer
  • Hans Ahr
  • Walter Janssens

Detail Information

Publications15

  1. pmc Predictive toxicology of cobalt ferrite nanoparticles: comparative in-vitro study of different cellular models using methods of knowledge discovery from data
    Limor Horev-Azaria
    Department of Physiology and Pharmacology, Faculty of Medicine and the Marian Gertner Institute for Medical Nanosystems, Tel Aviv University, Tel Aviv 69978, Israel
    Part Fibre Toxicol 10:32. 2013
    ..Cobalt-ferrite nanoparticles (Co-Fe NPs) are attractive for nanotechnology-based therapies. Thus, exploring their effect on viability of seven different cell lines representing different organs of the human body is highly important...
  2. doi request reprint Morphological transformation induced by multiwall carbon nanotubes on Balb/3T3 cell model as an in vitro end point of carcinogenic potential
    Jessica Ponti
    European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Nanobiosciences Unit, Ispra, VA, Italy
    Nanotoxicology 7:221-33. 2013
    ....
  3. doi request reprint Colony Forming Efficiency and microscopy analysis of multi-wall carbon nanotubes cell interaction
    Jessica Ponti
    European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Nanobiosciences Unit, 21027 Ispra, VA, Italy
    Toxicol Lett 197:29-37. 2010
    ....
  4. pmc Problems and challenges in the development and validation of human cell-based assays to determine nanoparticle-induced immunomodulatory effects
    Gertie J Oostingh
    Department of Molecular Biology, University of Salzburg, 5020 Salzburg, Austria
    Part Fibre Toxicol 8:8. 2011
    ..However, before assays can be standardised, it is important that suitable methods are established and validated...
  5. doi request reprint Online monitoring of cell metabolism to assess the toxicity of nanoparticles: the case of cobalt ferrite
    Valentina Mariani
    European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Nanobiosciences Unit, Ispra Va, Italy
    Nanotoxicology 6:272-87. 2012
    ..In conclusion, this work demonstrated that the measurement of metabolic parameters with a microphysiometer is a promising method to assess the toxicity of NPs and offers the advantage to follow on-line the cell metabolic changes...
  6. ncbi request reprint Assessment of cytotoxicity by impedance spectroscopy
    Laura Ceriotti
    European Commission, Joint Research Centre, Institute for Health and Consumer Protection, TP 203, via E Fermi 1, 21020 Ispra, VA, Italy
    Biosens Bioelectron 22:3057-63. 2007
    ..In term of impedance signal, the modulus results was found to be the most sensitive of the considered components for cytotoxicity testing of chemicals...
  7. doi request reprint Genotoxicity and morphological transformation induced by cobalt nanoparticles and cobalt chloride: an in vitro study in Balb/3T3 mouse fibroblasts
    Jessica Ponti
    Nanobiosciences Unit, European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Via E Fermi 2749, 21027 Ispra VA, Italy
    Mutagenesis 24:439-45. 2009
    ..Furthermore, we observed a higher cellular uptake of Co-nano compared with Co(2+)...
  8. doi request reprint Mechanisms of toxicity induced by SiO2 nanoparticles of in vitro human alveolar barrier: effects on cytokine production, oxidative stress induction, surfactant proteins A mRNA expression and nanoparticles uptake
    Lucian Romeo Farcal
    Institute for Health and Consumer Protection, Joint Research Centre, European Commission, Validation of Alternative Methods Unit EURL ECVAM, Via E Fermi 2749, Ispra Va, Italy
    Nanotoxicology 7:1095-110. 2013
    ..The obtained results suggested that in vitro approach can be used to study pulmonary toxicity as long as the applied in vitro model mimics closely the complexity of in vivo situation...
  9. ncbi request reprint Size-dependent toxicity and cell interaction mechanisms of gold nanoparticles on mouse fibroblasts
    Rosella Coradeghini
    Nanobiosciences Unit, Joint Research Centre, Institute for Health and Consumer Protection, European Commission, Via E Fermi 2749, 21027 Ispra, VA, Italy
    Toxicol Lett 217:205-16. 2013
    ..No significant effect was observed in the expression level of caveolin, while reduction of the expression and degradation of the clathrin heavy chain was observed in cells exposed for 72 h to AuNPs...
  10. doi request reprint Amorphous silica nanoparticles do not induce cytotoxicity, cell transformation or genotoxicity in Balb/3T3 mouse fibroblasts
    Chiara Uboldi
    European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Nanobiosciences Unit, TP203, Via E Fermi 2749, 21027, Ispra Va, Italy
    Mutat Res 745:11-20. 2012
    ....
  11. ncbi request reprint Development of a mechanistically-based genetically engineered PC12 cell system to detect p53-mediated cytotoxicity
    Erwin van Vliet
    European Centre for the Validation of Alternative Methods ECVAM, Institute for Health and Consumer Protection, European Commission Joint Research Centre, via E Fermi 1, 21020 Ispra VA, Italy
    Toxicol In Vitro 21:698-705. 2007
    ....
  12. ncbi request reprint Comparison of impedance-based sensors for cell adhesion monitoring and in vitro methods for detecting cytotoxicity induced by chemicals
    Jessica Ponti
    Joint Research Centre, BMS Unit, TP580, via E Fermi 1, 21020 Ispra, VA, Italy
    Altern Lab Anim 34:515-25. 2006
    ..The results show that the sensitivity of the developed chip was better than that with the MTT test, with the additional advantages of online monitoring...
  13. doi request reprint Cellular distribution and degradation of cobalt ferrite nanoparticles in Balb/3T3 mouse fibroblasts
    Patrick Marmorato
    European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Ispra Va, Italy
    Toxicol Lett 207:128-36. 2011
    ....
  14. ncbi request reprint Metabolism: a bottleneck in in vitro toxicological test development. The report and recommendations of ECVAM workshop 54
    Sandra Coecke
    ECVAM, Institute for Health and Consumer Protection, European Commission Joint Research Centre, Ispra, Italy
    Altern Lab Anim 34:49-84. 2006
  15. ncbi request reprint In vitro setting of dose-effect relationships of 32 metal compounds in the Balb/3T3 cell line, as a basis for predicting their carcinogenic potential
    Francesca Mazzotti
    ECVAM, Institute for Health and Consumer Protection, European Commission Joint Research Centre, 21020 Ispra, VA, Italy
    Altern Lab Anim 30:209-17. 2002
    ....