Raivo Uibo

Summary

Affiliation: University of Tartu
Country: Estonia

Publications

  1. ncbi request reprint Low prevalence of IgA anti-transglutaminase 1, 2, and 3 autoantibodies in children with atopic dermatitis
    Krista Ress
    Department of Immunology, Institute of Bio and Translational Medicine and Centre of Excellence for Translational Medicine, University of Tartu, Ravila 19, 50411 Tartu, Estonia
    BMC Res Notes 7:310. 2014
  2. doi request reprint Primary biliary cirrhosis: a multi-faced interactive disease involving genetics, environment and the immune response
    Raivo Uibo
    Institute of General and Molecular Pathology, Centre of Excellence for Translational Medicine, University of Tartu, Tartu, Estonia
    APMIS 120:857-71. 2012
  3. ncbi request reprint The epidemiology of primary biliary cirrhosis: immunological problems
    R Uibo
    Department of Immunology, University of Tartu, Estonia
    Hepatogastroenterology 46:3048-52. 1999
  4. doi request reprint Celiac disease in patients with type 1 diabetes: a condition with distinct changes in intestinal immunity?
    Raivo Uibo
    Department of Immunology, University of Tartu, Tartu, Estonia
    Cell Mol Immunol 8:150-6. 2011
  5. ncbi request reprint Contribution of epidemiological studies to gastritis immunology
    Raivo Uibo
    Department of Immunology, Institute of General and Molecular Pathology, University of Tartu, Tartu, Estonia
    Int Rev Immunol 24:31-54. 2005
  6. doi request reprint Lower expression of tight junction protein 1 gene and increased FOXP3 expression in the small bowel mucosa in coeliac disease and associated type 1 diabetes mellitus
    Tamara Vorobjova
    Institute of General and Molecular Pathology, Department of Immunology, University of Tartu, Ravila 19, Tartu, Estonia
    Int Arch Allergy Immunol 156:451-61. 2011
  7. ncbi request reprint Putative predictors of antibodies against follicle-stimulating hormone in female infertility: a study based on in vitro fertilization patients
    Kadri Haller
    Department of Immunology, Institute of General and Molecular Pathology, Centre of Molecular and Clinical Medicine, University of Tartu, Biomedicum, Ravila Str 19, Tartu 50411, Estonia
    Am J Reprod Immunol 57:193-200. 2007
  8. doi request reprint Antibodies to neurofilaments
    Ija Talja
    Immunology Group, Institute of General and Molecular Pathology, University of Tartu, Tartu, Estonia
    Ann N Y Acad Sci 1173:130-6. 2009
  9. ncbi request reprint Immune response to Helicobacter pylori and its association with the dynamics of chronic gastritis in the antrum and corpus
    Tamara Vorobjova
    Department of Immunology, Institute of General and Molecular Pathology, University of Tartu, Tartu, Estonia
    APMIS 116:465-76. 2008
  10. pmc Allelic variants in the PHTF1-PTPN22, C12orf30 and CD226 regions as candidate susceptibility factors for the type 1 diabetes in the Estonian population
    Konstantinos Douroudis
    Immunology Group, Institute of General and Molecular Pathology, University of Tartu, Tartu, Estonia
    BMC Med Genet 11:11. 2010

Detail Information

Publications57

  1. ncbi request reprint Low prevalence of IgA anti-transglutaminase 1, 2, and 3 autoantibodies in children with atopic dermatitis
    Krista Ress
    Department of Immunology, Institute of Bio and Translational Medicine and Centre of Excellence for Translational Medicine, University of Tartu, Ravila 19, 50411 Tartu, Estonia
    BMC Res Notes 7:310. 2014
    ..Since impairments to the epidermal barrier represent an important factor in AD, we hypothesized that IgA autoantibodies specific for TG1 (IgA-anti-TG1) and TG3 (IgA-anti-TG3) may affect AD development during childhood...
  2. doi request reprint Primary biliary cirrhosis: a multi-faced interactive disease involving genetics, environment and the immune response
    Raivo Uibo
    Institute of General and Molecular Pathology, Centre of Excellence for Translational Medicine, University of Tartu, Tartu, Estonia
    APMIS 120:857-71. 2012
    ..In this review, we will present an updated overview of PBC and place it in the context of autoimmunity...
  3. ncbi request reprint The epidemiology of primary biliary cirrhosis: immunological problems
    R Uibo
    Department of Immunology, University of Tartu, Estonia
    Hepatogastroenterology 46:3048-52. 1999
    ..In this paper the epidemiological data on PBC and its immunological marker--anti-mitochondrial antibodies--have been presented from a comparative viewpoint...
  4. doi request reprint Celiac disease in patients with type 1 diabetes: a condition with distinct changes in intestinal immunity?
    Raivo Uibo
    Department of Immunology, University of Tartu, Tartu, Estonia
    Cell Mol Immunol 8:150-6. 2011
    ....
  5. ncbi request reprint Contribution of epidemiological studies to gastritis immunology
    Raivo Uibo
    Department of Immunology, Institute of General and Molecular Pathology, University of Tartu, Tartu, Estonia
    Int Rev Immunol 24:31-54. 2005
    ....
  6. doi request reprint Lower expression of tight junction protein 1 gene and increased FOXP3 expression in the small bowel mucosa in coeliac disease and associated type 1 diabetes mellitus
    Tamara Vorobjova
    Institute of General and Molecular Pathology, Department of Immunology, University of Tartu, Ravila 19, Tartu, Estonia
    Int Arch Allergy Immunol 156:451-61. 2011
    ..We aimed to determine whether the expression of tight junction protein 1 (TJP1), which reflects small bowel mucosa permeability, is changed in CD and T1D...
  7. ncbi request reprint Putative predictors of antibodies against follicle-stimulating hormone in female infertility: a study based on in vitro fertilization patients
    Kadri Haller
    Department of Immunology, Institute of General and Molecular Pathology, Centre of Molecular and Clinical Medicine, University of Tartu, Biomedicum, Ravila Str 19, Tartu 50411, Estonia
    Am J Reprod Immunol 57:193-200. 2007
    ..Here, we investigated the parameters associated with anti-FSH antibodies in in vitro fertilization (IVF) patients...
  8. doi request reprint Antibodies to neurofilaments
    Ija Talja
    Immunology Group, Institute of General and Molecular Pathology, University of Tartu, Tartu, Estonia
    Ann N Y Acad Sci 1173:130-6. 2009
    ..In children with DS the presence of antibodies to NF-H might reflect a more favorable prognosis...
  9. ncbi request reprint Immune response to Helicobacter pylori and its association with the dynamics of chronic gastritis in the antrum and corpus
    Tamara Vorobjova
    Department of Immunology, Institute of General and Molecular Pathology, University of Tartu, Tartu, Estonia
    APMIS 116:465-76. 2008
    ..01; p=0.02), but is not associated with development of atrophy. Seropositivity for different H. pylori antigens (CagA, HSP 60) serves as a marker of different histological manifestations in the antrum and corpus mucosa...
  10. pmc Allelic variants in the PHTF1-PTPN22, C12orf30 and CD226 regions as candidate susceptibility factors for the type 1 diabetes in the Estonian population
    Konstantinos Douroudis
    Immunology Group, Institute of General and Molecular Pathology, University of Tartu, Tartu, Estonia
    BMC Med Genet 11:11. 2010
    ..Methods: The rs6679677 (1p13), rs17696736 (12q24) and rs763361 (18q22) were genotyped in a total of 230 controls and 154 type 1 diabetes patients of Estonian origin...
  11. doi request reprint Serum sTREM-1 (soluble triggering receptor expressed on myeloid cells-1) associates negatively with embryo quality in infertility patients
    Kadri Haller-Kikkatalo
    Immunology Group, Institute of General and Molecular Pathology, University of Tartu, Tartu, Estonia
    Am J Reprod Immunol 68:68-74. 2012
    ..Soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) is a useful biomarker of infection and inflammation...
  12. ncbi request reprint A modified ELISA for improved detection of IgA, IgG, and IgM anti-tissue transglutaminase antibodies in celiac disease
    Kaupo Teesalu
    Immunology Group, Department of General and Molecular Pathology, University of Tartu, Tartu, Estonia
    Clin Chim Acta 403:37-41. 2009
    ..A novel ELISA, using fibronectin (FN) as tTG binding protein, was evaluated for the detection of anti-tTG antibodies in CD...
  13. doi request reprint Serum anti-endometrial antibodies in infertile women - potential risk factor for implantation failure
    Aili Sarapik
    Department of Immunology, Institute of General and Molecular Pathology, University of Tartu, Biomedicum, Estonia
    Am J Reprod Immunol 63:349-57. 2010
    ..Female infertility patients with diverse etiologies show increased production of autoantibodies...
  14. doi request reprint Higher FoxP3 mRNA expression in peripheral blood mononuclear cells of GAD65 or IA-2 autoantibody-positive compared with autoantibody-negative persons
    Maire Link
    Immunology Group, IGMP, University of Tartu, Tartu, Estonia
    APMIS 116:896-902. 2008
    ..The ratio of the expression of different isoforms was not changed. This study shows the possible role of FoxP3 in the development of tissue characteristic humoral immunity in type 1 diabetes...
  15. pmc Characterization of the biological effect of fish fibrin glue in experiments on rats: immunological and coagulation studies
    Ivo Laidmäe
    Department of Immunology, University of Tartu, Ravila Street 19, Tartu 51014, Estonia
    J Biomed Mater Res A 93:29-36. 2010
    ..Taken together, blood immunological and coagulation parameters support the suitability of salmon-derived FG in the development of fibrin sealants for medical use...
  16. ncbi request reprint Antigenic proteins of Lactobacillus acidophilus that are recognised by serum IgG antibodies in children with type 1 diabetes and coeliac disease
    Anna Liisa Prangli
    Department of Immunology, IGMP, University of Tartu, Tartu, Estonia
    Pediatr Allergy Immunol 21:e772-9. 2010
    ..The different prevalence of reactions against tested antigens in patients and controls sera may indicate significant differences in immune system and commensal bacteria cross-talk in these groups...
  17. ncbi request reprint Screening for celiac disease in Down's syndrome patients revealed cases of subtotal villous atrophy without typical for celiac disease HLA-DQ and tissue transglutaminase antibodies
    Oivi Uibo
    Department of Paediatrics, University of Tartu, 6 Lunini Street, Tartu 51014, Estonia
    World J Gastroenterol 12:1430-4. 2006
    ..To investigate the prevalence of celiac disease (CD) as well as CD marker antibodies and susceptibility HLA-DQ haplotypes in 134 karyotyped Down's syndrome (DS) patients...
  18. doi request reprint Autoantibodies from patients with celiac disease inhibit transglutaminase 2 binding to heparin/heparan sulfate and interfere with intestinal epithelial cell adhesion
    Kaupo Teesalu
    Immunology Group, Department of General and Molecular Pathology, University of Tartu, Ravila 19, 50411, Tartu, Estonia
    Amino Acids 42:1055-64. 2012
    ....
  19. doi request reprint LADA and T1D in Estonian population - two different genetic risk profiles
    Kalle Kisand
    University of Tartu, Estonia
    Gene 497:285-91. 2012
    ..We hypothesized that the genetic predisposition is multiplicative and joint risk of different diabetic phenotypes forms by distinct combination of susceptibility loci...
  20. doi request reprint A 10-year serological follow-up of celiac disease in an Estonian population
    Kadri Lillemäe
    Immunology Group, Institute of General and Molecular Pathology and Center of Excellence for Translational Medicine, University Hospital, University of Tartu, Tartu, Estonia
    Eur J Gastroenterol Hepatol 24:55-8. 2012
    ..The results revealed a CD prevalence of 0.34%, which is lower compared with many other European countries...
  21. ncbi request reprint Response of IgG1 and IgG2 subclasses to Helicobacter pylori in subjects with chronic inflammation of the gastric mucosa, atrophy and gastric cancer in a country with high Helicobacter pylori infection prevalence
    Tamara Vorobjova
    Centre of Molecular and Clinical Medicine, Institute of General and Molecular Pathology, University of Tartu, Tartu, Estonia
    APMIS 114:372-80. 2006
    ..Higher value of CagA antibodies was seen in gastric cancer and in gastric atrophy compared with nonatrophic gastritis; in gastric cancer patients, IgG1 response to H. pylori was correlated with CagA status...
  22. ncbi request reprint Symptomless celiac disease in type 1 diabetes: 12-year experience in Estonia
    Oivi Uibo
    Department of Pediatrics, University of Tartu, Lunini 6, Tartu, 51014, Estonia
    Pediatr Int 52:230-3. 2010
    ..We aimed to determine the prevalence and characteristics of celiac disease in children with type 1 diabetes in Estonia, a country with a formerly low frequency of both diseases...
  23. ncbi request reprint Antibodies to Lactobacilli and Bifidobacteria in young children with different propensity to develop islet autoimmunity
    Ija Talja
    Immunology Group, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411 Tartu, Estonia
    J Immunol Res 2014:325938. 2014
    ..These results confirm that differences in immune reactivity against some commensal strains in young children may represent a different risk factor for developing T1D. ..
  24. ncbi request reprint Testis-expressed protein TSGA10 an auto-antigen in autoimmune polyendocrine syndrome type I
    Koit Reimand
    Immunology and Molecular Pathology Groups, Centre of Molecular and Clinical Medicine, University of Tartu, 19 Ravila Street, Tartu 50411, Estonia
    Int Immunol 20:39-44. 2008
    ..Nevertheless, their presence in a proportion of patients with APS1 highlights the role of TSGA10 as a target of immune reactions in APS1...
  25. pmc Follicular proinflammatory cytokines and chemokines as markers of IVF success
    Aili Sarapik
    Department of Immunology, Institute of General and Molecular Pathology, University of Tartu, Ravila 19, Tartu 50411, Estonia
    Clin Dev Immunol 2012:606459. 2012
    ..IL-12 positively correlated with oocyte fertilization and embryo development, while increased IL-18, IL-8, and MIP-1β were associated with successful IVF-induced pregnancy...
  26. ncbi request reprint Association of CTLA4 but not ICOS polymorphisms with type 1 diabetes in two populations with different disease rates
    Konstantinos Douroudis
    Immunology Group, IGMP, University of Tartu, Tartu, Estonia
    Hum Immunol 70:536-9. 2009
    ....
  27. ncbi request reprint CTLA-4 promoter polymorphisms are associated with latent autoimmune diabetes in adults
    Konstantinos Douroudis
    Immunology Group, Institute of General and Molecular Pathology, University of Tartu, Tartu, Estonia
    Hum Immunol 70:921-4. 2009
    ..The current study confirms the involvement of CTLA-4 gene promoter polymorphisms in the susceptibility of LADA and extends our previous findings of associations with other CTLA-4 polymorphisms...
  28. doi request reprint Increased FOXP3 expression in small-bowel mucosa of children with coeliac disease and type I diabetes mellitus
    Tamara Vorobjova
    Department of Immunology, Institute of General and Molecular Pathology, University of Tartu, Tartu, Estonia
    Scand J Gastroenterol 44:422-30. 2009
    ..To determine whether the expression of FOXP3 is changed in small-bowel mucosa in coeliac disease (CD)...
  29. doi request reprint Use of a fully automated immunoassay for celiac disease screening in a pediatric population
    Krista Ress
    Immunology Group, IGMP and CETM, University of Tartu, Tartu, Estonia
    Clin Chem Lab Med 49:983-7. 2011
    ..We compared the accuracy of IgA-anti-tTG detection using a fully automated fluoroenzyme immunoassay (FEIA) with that of the standard enzyme-linked immunosorbent assay (ELISA) in a clinical setting...
  30. ncbi request reprint Demonstration of natural autoantibodies against the neurofilament protein alpha-internexin in sera of patients with endocrine autoimmunity and healthy individuals
    Tarvo Rajasalu
    Department of Immunology, Institute of General and Molecular Pathology, University of Tartu, 19 Ravila Street, Tartu 51014, Estonia
    Immunol Lett 94:153-60. 2004
    ..This is the first demonstration of alpha-INX AAbs as one of the predominant neuronal IF AAbs in human sera...
  31. doi request reprint Celiac disease: a model disease for gene-environment interaction
    Raivo Uibo
    Immunology Group, IGMP, University of Tartu, Ravila 19, Tartu, Estonia
    Cell Mol Immunol 8:93-5. 2011
    ..This issue is devoted to this theme. The goal is not to discuss genetic and environmental interactions, but rather to focus on key elements of diagnosis, the inflammatory response and the mechanisms of autoimmunity...
  32. doi request reprint Kinetic and functional characterisation of the heparin-binding peptides from human transglutaminase 2
    Kaupo Teesalu
    Immunology Group, Department of General and Molecular Pathology, University of Tartu, Ravila 19, 50411, Tartu, Estonia
    J Pept Sci 18:350-6. 2012
    ..High immunoreactivity of the corresponding heparin-binding peptides of TG2 with CD patient's IgA supports the previously described role of anti-TG2 autoantibodies interfering with this interaction...
  33. pmc Review on autoimmune reactions in female infertility: antibodies to follicle stimulating hormone
    Kadri Haller-Kikkatalo
    Department of Immunology, Institute of General and Molecular Pathology, University of Tartu, Ravila Street 19, Biomedicum, Tartu 50411, Estonia
    Clin Dev Immunol 2012:762541. 2012
    ..In addition, the putative impairment of ovarian folliculogenesis in case of increased production of those antibodies in infertile women will be characterized...
  34. ncbi request reprint Circulating anti-follicle-stimulating hormone immunoglobulin A in women: a sperm-prone reaction of mucosal tolerance?
    Kadri Haller
    Department of Immunology, Institute of General and Molecular Pathology, Centre of Molecular and Clinical Medicine, University of Tartu, Tartu, Estonia
    Fertil Steril 90:1253-5. 2008
    ..Our results suggest that anti-FSH and anti-sperm IgA could share antigenic origin, being induced possibly by mucosal tolerance to semen...
  35. ncbi request reprint Propensity to excessive proinflammatory response in chronic Lyme borreliosis
    Kai E Kisand
    Department of Immunology, Institute of General and Molecular Pathology, Centre of Molecular and Clinical Medicine, Tartu, Estonia
    APMIS 115:134-41. 2007
    ..The percentage of CD4(+) CTLA-4(+) regulatory T cells showed the highest values in early Lyme borreliosis. We conclude that chronic forms of Lyme borreliosis can evolve due to an aberrant innate proinflammatory response...
  36. ncbi request reprint VNTR I/I genotype of insulin gene is associated with the increase of follicle number independent from polycystic ovary syndrome
    Kadri Haller
    Department of Immunology, Institute of General and Molecular Pathology, Centre of Molecular and Clinical Medicine, University of Tartu, Ravila 19, Tartu, Estonia
    Acta Obstet Gynecol Scand 86:726-32. 2007
    ..We analysed the minisatellite variations of the insulin gene (INS VNTR) with regard to the clinical features of PCOS...
  37. doi request reprint Newly-diagnosed pediatric epilepsy is associated with elevated autoantibodies to glutamic acid decarboxylase but not cardiolipin
    Kadi Veri
    Department of Pediatrics, University of Tartu, Lunini 6, Tartu 51014, Estonia
    Epilepsy Res 105:86-91. 2013
    ..Further studies are required to determine the prognostic significance and pathogenic role of GADA among pediatric subjects with epilepsy...
  38. doi request reprint Expression of B7 and CD28 family genes in newly diagnosed type 1 diabetes
    Katrin Pruul
    Department of Immunology, Institute of Biomedicine, University of Tartu, Ravila 19, Tartu 50411, Estonia Centre for Translational Medicine, University of Tartu, Ravila 19, Tartu 50411, Estonia
    Hum Immunol 74:1251-7. 2013
    ..To summarize, we expect that newly diagnosed T1D among children and adolescents is associated with activation of CD80 and CTLA4 in peripheral blood. Additional studies will be needed to elucidate the role of CD80/CTLA4 signaling in T1D...
  39. doi request reprint Survivin promoter polymorphisms and autoantibodies in endometriosis
    Merit Lamp
    Department of Obstetrics and Gynecology, University of Tartu, L Puusepa 8, 51014 Tartu, Estonia
    J Reprod Immunol 96:95-100. 2012
    ....
  40. ncbi request reprint Serological description of Estonian patients with Lyme disease, a comparison with control sera from endemic and non-endemic areas
    Kai E Kisand
    University of Tartu, Department of Immunology, Tartu, Estonia
    Int J Med Microbiol 293:174-8. 2004
    ..Also the rate of other infections, giving rise to cross-reactive antibodies, may be more frequent in Estonians. The frequent reactions with Borrelia antigens in a healthy population complicate the serodiagnosis of Lyme disease...
  41. ncbi request reprint Anti-FSH antibodies associate with poor outcome of ovarian stimulation in IVF
    Kadri Haller
    Department of Immunology, Institute of General and Molecular Pathology, Centre of Molecular and Clinical Medicine, University of Tartu, Ravila Str 19, Tartu 50411, Estonia
    Reprod Biomed Online 16:350-5. 2008
    ..Collectively, these data suggest that serum anti-FSH antibodies are associated with poor ovarian response to FSH stimulation in IVF, with anti-FSH IgA and IgG potentially exerting a local FSH antagonizing effect in maturing follicles...
  42. ncbi request reprint Development of a luciferase-based system for the detection of ZnT8 autoantibodies
    Julia Ustinova
    Department of Immunology, Institute of Biomedicine and Translational Medicine, Faculty of Medicine, University of Tartu, Estonia Centre of Excellence for Translational Medicine, University of Tartu, Estonia
    J Immunol Methods 405:67-73. 2014
    ..LIPS was less effective in detecting antibodies in children probably due to the relatively high prevalence of IgM anti-ZnT8 antibodies in children with T1D. ..
  43. pmc Interferon autoantibodies associated with AIRE deficiency decrease the expression of IFN-stimulated genes
    Kai Kisand
    Institute of General and Molecular Pathology, University of Tartu, Tartu, Estonia
    Blood 112:2657-66. 2008
    ..Our results argue that the breakdown of tolerance to IFNs in AIRE deficiency is associated with impaired responses to them in thymus, and highlight APECED as another autoimmune disease with associated dysregulation of IFN activity...
  44. doi request reprint Enterovirus infections in young infants: are children still protected by maternal antibodies?
    Liina Salur
    Immunology Group, Institute of General and Molecular Pathology, University of Tartu, Tartu, Estonia
    Hum Vaccin 7:966-71. 2011
    ..Considerable proportion of infants lack maternal antibodies against the virus causing their infection. The significance of this phenomenon needs to be evaluated in larger studies...
  45. ncbi request reprint Controlled ovarian hyperstimulation changes the prevalence of serum autoantibodies in in vitro fertilization patients
    Kadri Haller
    Department of Immunology, Institute of General and Molecular Pathology, Centre of Molecular and Clinical Medicine, University of Tartu, Tartu, Estonia
    Am J Reprod Immunol 56:364-70. 2006
    ..Controlled ovarian hyperstimulation (COH) with supraphysiological levels of sex hormones is achieved by IVF...
  46. doi request reprint Salmon fibrin glue in rats: antibody studies
    Ivo Laidmäe
    Immunology Group, IGMP University of Tartu, Ravila Street 19, Tartu 50411, Estonia
    Biologicals 40:55-60. 2012
    ..Before human use can be considered, however, additional data about safety of this preparation in other animal models, including large animal studies, should be obtained...
  47. ncbi request reprint IgG from patients with liver diseases inhibit mitochondrial respiration in permeabilized oxidative muscle cells: impaired function of intracellular energetic units?
    Lumme Kadaja
    Department of Pathophysiology, Faculty of Medicine, University of Tartu, Tartu, Estonia
    Mol Cell Biochem 256:291-303. 2004
    ....
  48. ncbi request reprint Stability, sterility, coagulation, and immunologic studies of salmon coagulation proteins with potential use for mammalian wound healing and cell engineering
    Ivo Laidmäe
    Department of Immunology, IGMP, University of Tartu, Ravila Street 19, Tartu 51014, Estonia
    Biomaterials 27:5771-9. 2006
    ..The results support the potential of salmon fibrin as an alternative to mammalian proteins in clinical applications...
  49. doi request reprint Thyroid autoimmunity and treatment response to escitalopram in major depression
    Triin Eller
    Department of Psychiatry, University of Tartu, Raja 31, 50417 Tartu, Estonia
    Nord J Psychiatry 64:253-7. 2010
    ..There is evidence that immune alterations play an important part in the pathogenesis of major depression. Thyroid autoimmunity has been found in association with major depression in several studies...
  50. doi request reprint GAD65 autoimmunity-clinical studies
    Raivo Uibo
    Department of Immunology, IGMP, Centre of Molecular and Clinical Medicine, University of Tartu, Tartu, Estonia
    Adv Immunol 100:39-78. 2008
    ..Additional controlled clinical trials are needed to uncover the mechanisms by which subcutaneous injections of recombinant human GAD65 may alter GAD65 autoreactivity...
  51. ncbi request reprint Autoimmune Activation toward Embryo Implantation is Rare in Immune-Privileged Human Endometrium
    Kadri Haller-Kikkatalo
    Immunology Group, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila Tartu, Estonia
    Semin Reprod Med 32:376-84. 2014
    ..Antibodies affecting human fertility in ways other than impairing implantation are outside the scope of the current article and will not be discussed. ..
  52. pmc Immune responses to bile-tolerant helicobacter species in patients with chronic liver diseases, a randomized population group, and healthy blood donors
    Olga Ananieva
    Department of Immunology, University of Tartu, 51014 Tartu, Estonia, Sweden
    Clin Diagn Lab Immunol 9:1160-4. 2002
    ..occurs. The antibody responses to H. hepaticus and H. bilis in CLD patients remained high following absorption experiments compared to ELISA results before absorption. The significance of this finding requires further investigations...
  53. ncbi request reprint Epitope mapping of cytochrome P450 cholesterol side-chain cleavage enzyme by sera from patients with autoimmune polyglandular syndrome type 1
    Ingrid Liiv
    Department of Immunology, Institute of General and Molecular Pathology, University of Tartu, 10 Ravila Street, Tartu, Estonia 51014
    Eur J Endocrinol 146:113-9. 2002
    ..In this study we describe autoantigenic epitopes on cholesterol side-chain cleavage enzyme (P450scc) using sera from Finnish and Sardinian patients with APS-1, and analyze the epitope reactivities during disease follow-up...
  54. ncbi request reprint IgG, IgA and IgM antibodies against FSH: serological markers of pathogenic autoimmunity or of normal immunoregulation?
    Kadri Haller
    Department of Immunology, Institute of General and Molecular Pathology and Centre of Molecular and Clinical Medicine, University of Tartu, Estonia
    Am J Reprod Immunol 54:262-9. 2005
    ..We aimed to study whether anti-FSH-antibodies might be involved in different clinical types of infertility...
  55. ncbi request reprint Demonstration of high prevalence of SS-A antibodies in a general population: association with HLA-DR and enterovirus antibodies
    Kaja Metskula
    Department of Immunology, Institute of General and Molecular Pathology, University of Tartu, Estonia
    Immunol Lett 106:14-8. 2006
    ..Whether all these persons have the risk of developing rheumatic diseases should be evaluated by follow up studies...
  56. ncbi request reprint Experimental autoimmune diabetes: a new tool to study mechanisms and consequences of insulin-specific autoimmunity
    Tarvo Rajasalu
    Division of Endocrinology, Department of Internal Medicine, University of Ulm, Robert Koch Strasse 8, D 89081 Ulm, Germany
    Ann N Y Acad Sci 1037:208-15. 2004
    ..1 for disease manifestation. Taken together, EAD is a novel, genetically defined animal model of type 1 diabetes suitable to analyze mechanisms and consequences of insulin-specific T cell autoimmunity...