Maia Kivisaar

Summary

Affiliation: Institute of Molecular and Cell Biology
Country: Estonia

Publications

  1. doi request reprint Mechanisms of stationary-phase mutagenesis in bacteria: mutational processes in pseudomonads
    Maia Kivisaar
    Department of Genetics, Estonian Biocentre, Institute of Molecular and Cell Biology, Tartu University, Tartu, Estonia
    FEMS Microbiol Lett 312:1-14. 2010
  2. ncbi request reprint Stationary phase mutagenesis: mechanisms that accelerate adaptation of microbial populations under environmental stress
    Maia Kivisaar
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, 51010 Tartu, Estonia
    Environ Microbiol 5:814-27. 2003
  3. doi request reprint Degradation of nitroaromatic compounds: a model to study evolution of metabolic pathways
    Maia Kivisaar
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, 23 Riia Street, 51010 Tartu, Estonia
    Mol Microbiol 74:777-81. 2009
  4. doi request reprint Evolution of catabolic pathways and their regulatory systems in synthetic nitroaromatic compounds degrading bacteria
    Maia Kivisaar
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, 23 Riia Street, 51010 Tartu, Estonia
    Mol Microbiol 82:265-8. 2011
  5. pmc Oxidative DNA damage defense systems in avoidance of stationary-phase mutagenesis in Pseudomonas putida
    Signe Saumaa
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, 23 Riia Street, 51010 Tartu, Estonia
    J Bacteriol 189:5504-14. 2007
  6. pmc The impact of ColRS two-component system and TtgABC efflux pump on phenol tolerance of Pseudomonas putida becomes evident only in growing bacteria
    Marta Putrins
    Institute of Molecular and Cell Biology, University of Tartu, 51010 Tartu, Estonia
    BMC Microbiol 10:110. 2010
  7. pmc A DNA polymerase V homologue encoded by TOL plasmid pWW0 confers evolutionary fitness on Pseudomonas putida under conditions of environmental stress
    Mariliis Tark
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, 23 Riia Street, 51010 Tartu, Estonia
    J Bacteriol 187:5203-13. 2005
  8. ncbi request reprint Study of involvement of ImuB and DnaE2 in stationary-phase mutagenesis in Pseudomonas putida
    Lauri Koorits
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, 23 Riia Street, 51010 Tartu, Estonia
    DNA Repair (Amst) 6:863-8. 2007
  9. doi request reprint Homologous recombination is facilitated in starving populations of Pseudomonas putida by phenol stress and affected by chromosomal location of the recombination target
    Kairi Tavita
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, Tartu, Estonia
    Mutat Res 737:12-24. 2012
  10. pmc Elevated mutation frequency in surviving populations of carbon-starved rpoS-deficient Pseudomonas putida is caused by reduced expression of superoxide dismutase and catalase
    Kairi Tarassova
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, 23 Riia Street, 51010 Tartu, Estonia
    J Bacteriol 191:3604-14. 2009

Collaborators

  • R Horak
  • Riho Teras
  • Remus T Dame
  • Paula A Kivistik
  • Priit Pruunsild
  • Herman J Heipieper
  • Radi Tegova
  • Andres Tover
  • Signe Saumaa
  • Mariliis Tark
  • Marta Putrins
  • Kairi Tarassova
  • Heili Ilves
  • Kairi Tavita
  • Julia Sidorenko
  • Tatjana Jatsenko
  • Lauri Koorits
  • Julia Jakovleva
  • Triinu Juurik
  • Katren Mikkel
  • Annika Teppo
  • Mariliis Tark-Dame
  • Grit Neumann
  • Hansjoerg Jerabek
  • Kärt Ukkivi
  • Hanna Moor
  • Anna Velts
  • Tanel Ilmjärv
  • Liisa Lilje
  • Ulle Saks
  • Gaily Kivi
  • Frieder Schauer
  • Liis Monson
  • Lagle Kasak

Detail Information

Publications27

  1. doi request reprint Mechanisms of stationary-phase mutagenesis in bacteria: mutational processes in pseudomonads
    Maia Kivisaar
    Department of Genetics, Estonian Biocentre, Institute of Molecular and Cell Biology, Tartu University, Tartu, Estonia
    FEMS Microbiol Lett 312:1-14. 2010
    ..coli. The aim of this review is to provide an overview of the results of studies of mutagenic processes in pseudomonads and to discuss these results in the light of the mechanisms of stationary-phase mutagenesis discovered in E. coli...
  2. ncbi request reprint Stationary phase mutagenesis: mechanisms that accelerate adaptation of microbial populations under environmental stress
    Maia Kivisaar
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, 51010 Tartu, Estonia
    Environ Microbiol 5:814-27. 2003
    ..Evidence for the presence of mutagenic pathways that have probably been evolved to control the mutation rate in a cell will be discussed...
  3. doi request reprint Degradation of nitroaromatic compounds: a model to study evolution of metabolic pathways
    Maia Kivisaar
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, 23 Riia Street, 51010 Tartu, Estonia
    Mol Microbiol 74:777-81. 2009
    ..These results provide strong evidence for the idea that promiscuity of proteins is an important step in the evolution of new functions...
  4. doi request reprint Evolution of catabolic pathways and their regulatory systems in synthetic nitroaromatic compounds degrading bacteria
    Maia Kivisaar
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, 23 Riia Street, 51010 Tartu, Estonia
    Mol Microbiol 82:265-8. 2011
    ..This research addresses some fundamental questions about bottlenecks to be solved during evolution of new catabolic operons...
  5. pmc Oxidative DNA damage defense systems in avoidance of stationary-phase mutagenesis in Pseudomonas putida
    Signe Saumaa
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, 23 Riia Street, 51010 Tartu, Estonia
    J Bacteriol 189:5504-14. 2007
    ..Since PolV is known to perform translesion synthesis past damaged bases in DNA (e.g., some oxidized forms of adenine), our results may imply that adenine oxidation products are also an important source of mutation in starving bacteria...
  6. pmc The impact of ColRS two-component system and TtgABC efflux pump on phenol tolerance of Pseudomonas putida becomes evident only in growing bacteria
    Marta Putrins
    Institute of Molecular and Cell Biology, University of Tartu, 51010 Tartu, Estonia
    BMC Microbiol 10:110. 2010
    ..The latter phenotype is significantly enhanced by the presence of phenol in growth medium. Here, we focused on identification of factors affecting phenol tolerance of the colR-deficient P. putida...
  7. pmc A DNA polymerase V homologue encoded by TOL plasmid pWW0 confers evolutionary fitness on Pseudomonas putida under conditions of environmental stress
    Mariliis Tark
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, 23 Riia Street, 51010 Tartu, Estonia
    J Bacteriol 187:5203-13. 2005
    ..putida population. The results of our study indicate that RecA is involved in the control of expression of the pWW0-encoded Pol V...
  8. ncbi request reprint Study of involvement of ImuB and DnaE2 in stationary-phase mutagenesis in Pseudomonas putida
    Lauri Koorits
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, 23 Riia Street, 51010 Tartu, Estonia
    DNA Repair (Amst) 6:863-8. 2007
    ..Similar antagonistic effects of DnaE2 and ImuB on mutagenesis appeared also in UV-mutagenesis study. This data distinguishes the DnaE2 of P. putida from its homologues studied in other organisms...
  9. doi request reprint Homologous recombination is facilitated in starving populations of Pseudomonas putida by phenol stress and affected by chromosomal location of the recombination target
    Kairi Tavita
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, Tartu, Estonia
    Mutat Res 737:12-24. 2012
    ..We hypothesize that the binding of these proteins imposes differences in local structural organization of the genome that could affect the accessibility of the chromosomal DNA to HR processes and thereby the frequency of HR...
  10. pmc Elevated mutation frequency in surviving populations of carbon-starved rpoS-deficient Pseudomonas putida is caused by reduced expression of superoxide dismutase and catalase
    Kairi Tarassova
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, 23 Riia Street, 51010 Tartu, Estonia
    J Bacteriol 191:3604-14. 2009
    ..putida may be caused both by oxidative damage of DNA and enzymes involved in DNA replication and repair fidelity...
  11. doi request reprint Fis negatively affects binding of Tn4652 transposase by out-competing IHF from the left end of Tn4652
    Riho Teras
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, 51010 Tartu, Estonia
    Microbiology 155:1203-14. 2009
    ..Thus, the results obtained in this study indicate that the transposition of Tn4652 is regulated by the cellular amount of P. putida global regulators Fis and IHF...
  12. doi request reprint Involvement of specialized DNA polymerases Pol II, Pol IV and DnaE2 in DNA replication in the absence of Pol I in Pseudomonas putida
    Julia Sidorenko
    Department of Genetics, Tartu University and Estonian Biocentre, Tartu, Estonia
    Mutat Res 714:63-77. 2011
    ....
  13. ncbi request reprint Study of factors which negatively affect expression of the phenol degradation operon pheBA in Pseudomonas putida
    Marta Putrins
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, 51010 Tartu, Estonia
    Microbiology 153:1860-71. 2007
    ....
  14. ncbi request reprint Involvement of DNA mismatch repair in stationary-phase mutagenesis during prolonged starvation of Pseudomonas putida
    Signe Saumaa
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, 23 Riia Street, 51010 Tartu, Estonia
    DNA Repair (Amst) 5:505-14. 2006
    ..putida on the same selective plates hint that competitive interactions taking place under conditions of prolonged starvation of microbial populations on semi-solid surfaces might be more complicated than previously assumed...
  15. ncbi request reprint Dual role of NER in mutagenesis in Pseudomonas putida
    Mariliis Tark
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, 23 Riia Street, 51010 Tartu, Estonia
    DNA Repair (Amst) 7:20-30. 2008
    ..putida-besides functioning in repair of damaged DNA, NER is also important in generation of mutations. We hypothesize that NER enzymes may initiate gratuitous DNA repair and the following DNA repair synthesis might be mutagenic...
  16. doi request reprint ColRS two-component system prevents lysis of subpopulation of glucose-grown Pseudomonas putida
    Marta Putrins
    Estonian Biocentre and Institute of Molecular and Cell Biology, Tartu University, 51010 Tartu, Estonia
    Environ Microbiol 10:2886-93. 2008
    ....
  17. pmc Mutation frequency and spectrum of mutations vary at different chromosomal positions of Pseudomonas putida
    Triinu Juurik
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, Estonia
    PLoS ONE 7:e48511. 2012
    ..Also, artificial increasing transcription of the mutational target gene elevated the frequency of mutations in growing bacteria...
  18. pmc Identification of ColR binding consensus and prediction of regulon of ColRS two-component system
    Paula A Kivistik
    Estonian Biocentre and Institute of Molecular and Cell Biology, Tartu University, Tartu 51010, Estonia
    BMC Mol Biol 10:46. 2009
    ..In order to discover molecular mechanisms behind these phenotypes, we focused here on identification of downstream components of ColRS signal transduction pathway...
  19. doi request reprint Fis regulates the competitiveness of Pseudomonas putida on barley roots by inducing biofilm formation
    Julia Jakovleva
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, Tartu, Estonia
    Microbiology 158:708-20. 2012
    ..It is possible that the elevated expression of Fis is important in the adaptation of P. putida during colonization of plant roots by promoting biofilm formation when the migration of bacteria is no longer favoured...
  20. ncbi request reprint The ColR-ColS two-component signal transduction system is involved in regulation of Tn4652 transposition in Pseudomonas putida under starvation conditions
    Rita Hõrak
    Estonian Biocentre and Institute of Molecular and Cell Biology, Tartu University, 51010 Tartu, Estonia
    Mol Microbiol 54:795-807. 2004
    ..To our knowledge, Tn4652 is the first bacterial transposon regulated by a two-component system. This finding indicates that transpositional activity can respond to signals sensed and processed by the host...
  21. pmc The ColRS two-component system regulates membrane functions and protects Pseudomonas putida against phenol
    Paula Ann Kivistik
    Estonian Biocentre and Institute of Molecular and Cell Biology, Tartu University, 51010 Tartu, Estonia
    J Bacteriol 188:8109-17. 2006
    ..Thus, the current study revealed the role of the ColRS two-component system in regulation of membrane functionality, particularly in phenol tolerance of P. putida...
  22. pmc Target site selection of Pseudomonas putida transposon Tn4652
    Paula Ann Kivistik
    Estonian Biocentre and Institute of Molecular and Cell Biology, Tartu University, 51010 Tartu, Estonia
    J Bacteriol 189:3918-21. 2007
    ..Alignment of 93 different insertion sites revealed a consensus sequence which resembles that of Tn3, indicating that despite a low similarity between Tn4652 and Tn3 transposases, their target site recognition is conserved...
  23. doi request reprint Molecular characterization of Rif(r) mutations in Pseudomonas aeruginosa and Pseudomonas putida
    Tatjana Jatsenko
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University, Tartu, Estonia
    Mutat Res 683:106-14. 2010
    ....
  24. pmc Involvement of error-prone DNA polymerase IV in stationary-phase mutagenesis in Pseudomonas putida
    Radi Tegova
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, 23 Riia Street, 51010 Tartu, Estonia
    J Bacteriol 186:2735-44. 2004
    ..Therefore, we hypothesize that mechanisms different from the classical RecA-dependent SOS response could elevate Pol IV-dependent mutagenesis in starving P. putida cells...
  25. ncbi request reprint IHF is the limiting host factor in transposition of Pseudomonas putida transposon Tn4652 in stationary phase
    Heili Ilves
    Estonian Biocentre and Institute of Molecular and Cell Biology, Tartu University, 23 Riia Street, 51010 Tartu, Estonia
    Mol Microbiol 51:1773-85. 2004
    ..The results obtained in this study indicate that, besides sigma S, IHF is another host factor that is implicated in the elevation of transposition in stationary phase...
  26. pmc Different spectra of stationary-phase mutations in early-arising versus late-arising mutants of Pseudomonas putida: involvement of the DNA repair enzyme MutY and the stationary-phase sigma factor RpoS
    Signe Saumaa
    Department of Genetics, Institute of Molecular and Cell Biology, Tartu University and Estonian Biocentre, Estonia
    J Bacteriol 184:6957-65. 2002
    ..putida MutY-defective strain. The occurrence of 2- to 3-bp deletions required the stationary-phase sigma factor RpoS, which indicates that some mutagenic pathway is positively controlled by RpoS in P. putida...
  27. pmc Simultaneous degradation of atrazine and phenol by Pseudomonas sp. strain ADP: effects of toxicity and adaptation
    Grit Neumann
    Department of Bioremediation, Centre for Environmental Research UFZ Leipzig Halle, 04318 Leipzig, Germany
    Appl Environ Microbiol 70:1907-12. 2004
    ....