Christian Erikstrup

Summary

Publications

  1. ncbi request reprint Schistosomiasis and HIV-1 infection in rural Zimbabwe: implications of coinfection for excretion of eggs
    Per Kallestrup
    Center of Inflammation and Metabolism, Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
    J Infect Dis 191:1311-20. 2005
  2. doi request reprint T-cell dysfunction in HIV-1-infected patients with impaired recovery of CD4 cells despite suppression of viral replication
    Christian Erikstrup
    Department of Clinical Immunology, Aarhus University Hospital, Skejby, Brendstrupgaardsvej 100, DK 8200 Aarhus N, Denmark
    J Acquir Immune Defic Syndr 53:303-10. 2010
  3. ncbi request reprint Schistosomiasis and infection with human immunodeficiency virus 1 in rural Zimbabwe: systemic inflammation during co-infection and after treatment for schistosomiasis
    Christian Erikstrup
    Department of Clinical Immunology, Aarhus University Hospital, Skejby Sygehus, Aarhus, Denmark
    Am J Trop Med Hyg 79:331-7. 2008
  4. ncbi request reprint HLA-G 3' untranslated region 14-base pair deletion: association with poor survival in an HIV-1-infected Zimbabwean population
    Margit Hørup Larsen
    Department of Clinical Immunology, Copenhagen University Hospital Blegdamsvej 9, DK 2100 Copenhagen Ø, Denmark
    J Infect Dis 207:903-6. 2013
  5. pmc Hepatitis B and Delta virus are prevalent but often subclinical co-infections among HIV infected patients in Guinea-Bissau, West Africa: a cross-sectional study
    Bo Langhoff Hønge
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark
    PLoS ONE 9:e99971. 2014
  6. doi request reprint CCL3L gene copy number and survival in an HIV-1 infected Zimbabwean population
    Margit Hørup Larsen
    Department of Clinical Immunology, Copenhagen University Hospital, Denmark
    Infect Genet Evol 12:1087-93. 2012
  7. doi request reprint Predictors of iron levels in 14,737 Danish blood donors: results from the Danish Blood Donor Study
    Andreas Stribolt Rigas
    Department of Clinical Immunology, Copenhagen University Hospital, Copenhagen, Denmark
    Transfusion 54:789-96. 2014
  8. doi request reprint Plasma cytokine levels in Tanzanian HIV-1-infected adults and the effect of antiretroviral treatment
    Judith M Haissman
    Department of Clinical Immunology, Copenhagen University Hospital, Copenhagen, Denmark
    J Acquir Immune Defic Syndr 52:493-7. 2009
  9. ncbi request reprint Performance of 3 rapid tests for discrimination between HIV-1 and HIV-2 in Guinea-Bissau, West Africa
    Bo Langhoff Hønge
    Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau National HIV Programme, Ministry of Health, Bissau, Guinea Bissau National Public Health Laboratory, Bissau, Guinea Bissau GloHAU, Center for Global Health, School of Public Health, Aarhus University, Aarhus, Denmark and Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark
    J Acquir Immune Defic Syndr 65:87-90. 2014
  10. ncbi request reprint Polymorphism in interleukin-7 receptor α gene is associated with faster CD4+ T-cell recovery after initiation of combination antiretroviral therapy
    Hans J Hartling
    aDepartment of Infectious Diseases, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark bViro Immunology Research Unit cDepartment of Clinical Immunology, Rigshospitalet, Copenhagen University Hospital, Copenhagen dDepartment of Clinical Immunology, Aarhus University Hospital, Aarhus eDepartment of Infectious Diseases, Hvidovre, Copenhagen University Hospital, Copenhagen fDepartment of Infectious Diseases, Odense University Hospital, Odense gDepartment of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark
    AIDS 28:1739-48. 2014

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Schistosomiasis and HIV-1 infection in rural Zimbabwe: implications of coinfection for excretion of eggs
    Per Kallestrup
    Center of Inflammation and Metabolism, Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
    J Infect Dis 191:1311-20. 2005
    ..This study explores the effect that HIV-1-associated immunodeficiency has on the excretion of schistosome eggs in a large cohort of coinfected individuals...
  2. doi request reprint T-cell dysfunction in HIV-1-infected patients with impaired recovery of CD4 cells despite suppression of viral replication
    Christian Erikstrup
    Department of Clinical Immunology, Aarhus University Hospital, Skejby, Brendstrupgaardsvej 100, DK 8200 Aarhus N, Denmark
    J Acquir Immune Defic Syndr 53:303-10. 2010
    ..CD4 T-cell recovery is impeded in some HIVinfected patients despite successful combination antiretroviral therapy (cART) with suppressed HIV RNA. We hypothesized that T-cell dysfunction would be increased in these patients...
  3. ncbi request reprint Schistosomiasis and infection with human immunodeficiency virus 1 in rural Zimbabwe: systemic inflammation during co-infection and after treatment for schistosomiasis
    Christian Erikstrup
    Department of Clinical Immunology, Aarhus University Hospital, Skejby Sygehus, Aarhus, Denmark
    Am J Trop Med Hyg 79:331-7. 2008
    ..Treatment for schistosomiasis caused a decrease in levels of sTNF-rII (P < 0.05) and IL-10 (P < 0.001). Our results indicate that schistosomiasis treatment may attenuate HIV replication by decreasing systemic inflammation...
  4. ncbi request reprint HLA-G 3' untranslated region 14-base pair deletion: association with poor survival in an HIV-1-infected Zimbabwean population
    Margit Hørup Larsen
    Department of Clinical Immunology, Copenhagen University Hospital Blegdamsvej 9, DK 2100 Copenhagen Ø, Denmark
    J Infect Dis 207:903-6. 2013
    ..004), lower CD4 cell count (P = .01), and increased mortality (hazard ratio, 1.9; 95% confidence interval, 1.033-3.522; P = .04) compared with HLA-G +14-bp carriers...
  5. pmc Hepatitis B and Delta virus are prevalent but often subclinical co-infections among HIV infected patients in Guinea-Bissau, West Africa: a cross-sectional study
    Bo Langhoff Hønge
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark
    PLoS ONE 9:e99971. 2014
    ..Co or super-infection with hepatitis Delta virus (HDV) may worsen the liver disease and complicate treatment possibilities...
  6. doi request reprint CCL3L gene copy number and survival in an HIV-1 infected Zimbabwean population
    Margit Hørup Larsen
    Department of Clinical Immunology, Copenhagen University Hospital, Denmark
    Infect Genet Evol 12:1087-93. 2012
    ..9), viral load (P=0.9), or CCL3 protein levels (P=1.0). Survival among the HIV infected individuals did not differ according to CCL3L copy number. In this cohort, CCL3L CNV did not affect HIV status, pathogenesis, or survival...
  7. doi request reprint Predictors of iron levels in 14,737 Danish blood donors: results from the Danish Blood Donor Study
    Andreas Stribolt Rigas
    Department of Clinical Immunology, Copenhagen University Hospital, Copenhagen, Denmark
    Transfusion 54:789-96. 2014
    ..However, the impact of dietary factors on the iron stores of blood donors, whose iron status is affected by blood donations, is incompletely understood...
  8. doi request reprint Plasma cytokine levels in Tanzanian HIV-1-infected adults and the effect of antiretroviral treatment
    Judith M Haissman
    Department of Clinical Immunology, Copenhagen University Hospital, Copenhagen, Denmark
    J Acquir Immune Defic Syndr 52:493-7. 2009
    ..To evaluate the role immune activation leading to the production and circulation of cytokines has in the pathogenesis of HIV infection in sub-Saharan Africa and the effect of antiretroviral treatment (ART) on these parameters...
  9. ncbi request reprint Performance of 3 rapid tests for discrimination between HIV-1 and HIV-2 in Guinea-Bissau, West Africa
    Bo Langhoff Hønge
    Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau National HIV Programme, Ministry of Health, Bissau, Guinea Bissau National Public Health Laboratory, Bissau, Guinea Bissau GloHAU, Center for Global Health, School of Public Health, Aarhus University, Aarhus, Denmark and Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark
    J Acquir Immune Defic Syndr 65:87-90. 2014
    ..8%), followed by Immunoflow HIV1-HIV2 (agreement 90.9%) and SD Bioline HIV-1/2 3.0 (agreement 84.5%). Our results underscore the need for evaluation of tests in relevant populations before implementation...
  10. ncbi request reprint Polymorphism in interleukin-7 receptor α gene is associated with faster CD4+ T-cell recovery after initiation of combination antiretroviral therapy
    Hans J Hartling
    aDepartment of Infectious Diseases, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark bViro Immunology Research Unit cDepartment of Clinical Immunology, Rigshospitalet, Copenhagen University Hospital, Copenhagen dDepartment of Clinical Immunology, Aarhus University Hospital, Aarhus eDepartment of Infectious Diseases, Hvidovre, Copenhagen University Hospital, Copenhagen fDepartment of Infectious Diseases, Odense University Hospital, Odense gDepartment of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark
    AIDS 28:1739-48. 2014
    ..To investigate single-nucleotide polymorphisms (SNPs) in the gene encoding interleukin-7 receptor α (IL7RA) as predictors for CD4 T-cell change after initiation of combination antiretroviral therapy (cART) in HIV-infected whites...
  11. pmc The impact of B-cell perturbations on pneumococcal conjugate vaccine response in HIV-infected adults
    Thomas G Johannesson
    Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark
    PLoS ONE 7:e42307. 2012
    ....
  12. doi request reprint No evidence for an anti-inflammatory effect of escitalopram intervention in healthy individuals with a family history of depression
    Eva Haastrup
    Department of Clinical Immunology, Blood Bank, National University Hospital, Copenhagen, Denmark
    J Neuroimmunol 243:69-72. 2012
    ..Our data does thus not support the hypothesis of a global anti-inflammatory effect of escitalopram on cytokines in healthy subjects...
  13. pmc Combined oral contraception and obesity are strong predictors of low-grade inflammation in healthy individuals: results from the Danish Blood Donor Study (DBDS)
    Cecilie J Sørensen
    Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark
    PLoS ONE 9:e88196. 2014
    ..The aim of this study was to identify predictors of increased CRP levels in healthy individuals. We therefore assessed CRP in a large cohort of blood donors...
  14. doi request reprint A genetic risk factor for low serum ferritin levels in Danish blood donors
    Erik Sørensen
    Department of Clinical Immunology, Capital Region, Copenhagen University Hospital, Denmark
    Transfusion 52:2585-9. 2012
    ..Knowledge of genetic variants that predispose donors to iron deficiency would allow bleeding frequency and iron supplementation to be tailored to the individual donor...
  15. doi request reprint p24 as a predictor of mortality in a cohort of HIV-1-infected adults in rural Africa
    Christian Erikstrup
    The Centre of Inflammation and Metabolism, Rigshospitalet and Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
    J Acquir Immune Defic Syndr 48:345-9. 2008
    ..p24 measurements have been proposed as an alternative to HIV-RNA because of the low cost of reagents and equipment needed. Here, we evaluate p24 as a prognostic marker in a cohort of HIV-1-infected individuals in Zimbabwe...
  16. ncbi request reprint Reduced mortality and CD4 cell loss among carriers of the interleukin-10 -1082G allele in a Zimbabwean cohort of HIV-1-infected adults
    Christian Erikstrup
    Centre for Inflammation and Metabolism, Denmark
    AIDS 21:2283-91. 2007
    ..To evaluate the effect on HIV progression of single nucleotide polymorphisms in promoters of the genes for tumour necrosis factor (TNF)-alpha and interleukin (IL)-10 and known to influence cytokine production...
  17. ncbi request reprint Predictors of mortality in a cohort of HIV-1-infected adults in rural Africa
    Christian Erikstrup
    Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Denmark
    J Acquir Immune Defic Syndr 44:478-83. 2007
    ..We explored the prognostic strengths of classic and alternative progression markers in this study set in rural Zimbabwe...
  18. ncbi request reprint Schistosomiasis and HIV in rural Zimbabwe: efficacy of treatment of schistosomiasis in individuals with HIV coinfection
    Per Kallestrup
    Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    Clin Infect Dis 42:1781-9. 2006
    ..Consequently, human immunodeficiency virus (HIV)-related immunodeficiency may impair the effect of praziquantel treatment...
  19. ncbi request reprint Schistosomiasis and HIV-1 infection in rural Zimbabwe: effect of treatment of schistosomiasis on CD4 cell count and plasma HIV-1 RNA load
    Per Kallestrup
    Center for Inflammation and Metabolism, Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
    J Infect Dis 192:1956-61. 2005
    ..17). The present study suggests that treatment of schistosomiasis can reduce the rate of viral replication and increase CD4 cell count in the coinfected host...