Eudraginated polymer blends: a potential oral controlled drug delivery system for theophyllineMartins Emeje
Department of Pharmaceutical Technology and Raw Materials Development, National Institute for Pharmaceutical Research and Development, Abuja, Nigeria
Acta Pharm 62:71-82. 2012
..05) higher than those for Asmanyl(®), revealing relative bioavailability of about 136.93 %. Our study demonstrated the potential usefulness of eudraginated polymers for the oral delivery of the sparingly soluble drug theophylline...
- Natural antidiabetic compound for the therapeutic management of diabetes mellitus and its drug delivery system
Martins Emeje
Department of Pharmaceutical Technology and Raw Material Development, National Institute for Pharmaceutical Research and Development, Abuja, Nigeria
J Diet Suppl 8:266-79. 2011
..It is concluded that incorporation of Avicel as a filler-binder in AD1 preparation produced tablets of suitable compaction properties and ensured adequate drug release for the therapeutic management of diabetes mellitus...
Compaction characteristics of ethylcellulose in the presence of some channeling agents: technical noteM O Emeje
Department of Pharmaceutical Technology and Raw Material Development, National Institute for Pharmaceutical Research and Development, Abuja, Nigeria
AAPS PharmSciTech 7:58. 2006
- Effect of the molecular size of carboxymethylcellulose and some polymers on the sustained release of theophylline from a hydrophilic matrix
Martins O Emeje
Department of Pharmaceutical Technology and Raw Material Development, National Institute for Pharmaceutical Research and Development NIPRD, Idu P M B 21 Garki Abuja, Nigeria
Acta Pharm 56:325-35. 2006
..The drug release mechanism was influenced by both the molecular size of cmc and the presence of polymer additives...
- Preparation and evaluation of colon targeted drug delivery systems for albendazole using kneading, extrusion and compaction technology
Martins Emeje
Department of Pharmaceutical Technology and Raw Materials Development, National Institute for Pharmaceutical Research and Development, Abuja, Nigeria
Yao Xue Xue Bao 44:1152-8. 2009
..Matrix tablets containing blends of these polymers formulated using kneading, extrusion and compaction technique could provide sustained drug release and can be utilized in the colonic delivery of albendazole...
- Preparation and standardization of a herbal agent for the therapeutic management of asthma
Martins Emeje
Department of Pharmaceutical Technology and Raw Materials Development, National Institute for Pharmaceutical Research and Development NIPRD, Idu, Abuja, Nigeria
Pharm Dev Technol 16:170-8. 2011
..It is concluded that incorporation of Explotab (10%w/w) as a disintegrant in AA1 preparation produced tablets of suitable compressional properties and ensured adequate drug release for the management of acute asthma...
- Evaluation of the fluid uptake kinetics and drug release from gellan gum tablets containing metronidazole
M O Emeje
Department of Pharmaceutical Technology and Industrial Pharmacy, University of Nigeria, Nsukka, Enugu State, Nigeria
Int J Biol Macromol 47:158-63. 2010
..277 and 7.600 mm(3)/min respectively. The gum was most effective as a disintegrant for metronidazole tablets at an optimum concentration of 0.2% (w/w) when incorporated extra-granularly...
- Oral sustained release tablets of zidovudine using binary blends of natural and synthetic polymers
Martins Emeje
Department of Pharmaceutical Technology and Raw Materials Development, National Institute for Pharmaceutical Research and Development, Abuja, Nigeria
Biol Pharm Bull 33:1561-7. 2010
..Drug release from matrix tablets of zidovudine containing blends of AEG and C71 demonstrates the advantage of blending a natural and synthetic polymer over single polymer use...
- Some compaction characteristics of the hot water leaf extract og Nauclea latifiola: a potential antimalarial agent
M O Emeje
Department of Pharmaceutical Technology and Raw Materials Development, National Institute for Pharmaceutical Research and Development (NIPRD) Abuja, Nigeria
J Herb Pharmacother 5:23-30. 2005
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