Merrill Elias

Summary

Publications

  1. ncbi The preclinical phase of alzheimer disease: A 22-year prospective study of the Framingham Cohort
    M F Elias
    Department of Mathematics and Statistics, Statistical Consulting Unit, 111 Cummington St, Boston University College of Arts and Sciences, Boston, MA 02215, USA
    Arch Neurol 57:808-13. 2000
  2. pmc Chronic kidney disease, creatinine and cognitive functioning
    Merrill F Elias
    Department of Psychology, Graduate School of Biomedical Sciences, University of Maine, Orono, ME, USA
    Nephrol Dial Transplant 24:2446-52. 2009
  3. pmc Arterial pulse wave velocity and cognition with advancing age
    Merrill F Elias
    Department of Psychology and Graduate School of Biomedical Sciences, 5472 Little Hall, University of Maine, Orono, ME 04469, USA
    Hypertension 53:668-73. 2009
  4. ncbi Homocysteine and cognitive performance: modification by the ApoE genotype
    Merrill F Elias
    Department of Psychology, University of Maine, Orono, ME 04469, USA
    Neurosci Lett 430:64-9. 2008
  5. ncbi Left ventricular mass, blood pressure, and lowered cognitive performance in the Framingham offspring
    Merrill F Elias
    Statistics and Consulting Unit, Department of Mathematics and Statistics, Boston University, Mass, USA
    Hypertension 49:439-45. 2007
  6. ncbi Homocysteine, folate, and vitamins B6 and B12 blood levels in relation to cognitive performance: the Maine-Syracuse study
    Merrill F Elias
    Department of Psychology, University of Maine, Orono, Maine, USA
    Psychosom Med 68:547-54. 2006
  7. ncbi Obesity, diabetes and cognitive deficit: The Framingham Heart Study
    Merrill F Elias
    Boston University, Department of Mathematics and Statistics, Statistics and Consulting Unit, 111 Cummington Street, Boston, MA 02215, USA
    Neurobiol Aging 26:11-6. 2005
  8. ncbi Homocysteine and cognitive performance in the Framingham offspring study: age is important
    Merrill F Elias
    The Statistics and Consulting Unit, Department of Mathematics and Statistics, Boston University, Boston, MA, USA
    Am J Epidemiol 162:644-53. 2005
  9. doi From blood pressure to physical disability: the role of cognition
    Merrill F Elias
    Department of Psychology, University of Maine, Orono, ME 04469 5742, USA
    Hypertension 55:1360-5. 2010
  10. ncbi Lower cognitive function in the presence of obesity and hypertension: the Framingham heart study
    M F Elias
    Department of Mathematics and Statistics, Statistics and Consulting Unit, Boston University, MA 02215, USA
    Int J Obes Relat Metab Disord 27:260-8. 2003

Research Grants

Detail Information

Publications24

  1. ncbi The preclinical phase of alzheimer disease: A 22-year prospective study of the Framingham Cohort
    M F Elias
    Department of Mathematics and Statistics, Statistical Consulting Unit, 111 Cummington St, Boston University College of Arts and Sciences, Boston, MA 02215, USA
    Arch Neurol 57:808-13. 2000
    ..To relate performance on tests of cognitive ability to the subsequent development of probable Alzheimer disease (pAD) and to identify the pattern of earliest changes in cognitive functioning associated with a diagnosis of pAD...
  2. pmc Chronic kidney disease, creatinine and cognitive functioning
    Merrill F Elias
    Department of Psychology, Graduate School of Biomedical Sciences, University of Maine, Orono, ME, USA
    Nephrol Dial Transplant 24:2446-52. 2009
    ..We examined the range of specific cognitive abilities affected by CKD and whether the associations of CKD with cognition were eliminated by statistical control for cardiovascular disease correlates of CKD...
  3. pmc Arterial pulse wave velocity and cognition with advancing age
    Merrill F Elias
    Department of Psychology and Graduate School of Biomedical Sciences, 5472 Little Hall, University of Maine, Orono, ME 04469, USA
    Hypertension 53:668-73. 2009
    ..Early interventions to prevent an increase in arterial stiffness could possibly play an important role in the preservation of cognitive ability...
  4. ncbi Homocysteine and cognitive performance: modification by the ApoE genotype
    Merrill F Elias
    Department of Psychology, University of Maine, Orono, ME 04469, USA
    Neurosci Lett 430:64-9. 2008
    ..Presence of the ApoE-epsilon4 allele modifies the relation between plasma homocysteine and cognitive performance...
  5. ncbi Left ventricular mass, blood pressure, and lowered cognitive performance in the Framingham offspring
    Merrill F Elias
    Statistics and Consulting Unit, Department of Mathematics and Statistics, Boston University, Mass, USA
    Hypertension 49:439-45. 2007
    ....
  6. ncbi Homocysteine, folate, and vitamins B6 and B12 blood levels in relation to cognitive performance: the Maine-Syracuse study
    Merrill F Elias
    Department of Psychology, University of Maine, Orono, Maine, USA
    Psychosom Med 68:547-54. 2006
    ....
  7. ncbi Obesity, diabetes and cognitive deficit: The Framingham Heart Study
    Merrill F Elias
    Boston University, Department of Mathematics and Statistics, Statistics and Consulting Unit, 111 Cummington Street, Boston, MA 02215, USA
    Neurobiol Aging 26:11-6. 2005
    ..To determine the independent effects of obesity on cognitive performance and to examine interactions between obesity and non-insulin dependent diabetes mellitus (NIDDM)...
  8. ncbi Homocysteine and cognitive performance in the Framingham offspring study: age is important
    Merrill F Elias
    The Statistics and Consulting Unit, Department of Mathematics and Statistics, Boston University, Boston, MA, USA
    Am J Epidemiol 162:644-53. 2005
    ..Early preventive interventions may be important, because the inverse association between tHcy and cognitive performance is observed beyond middle age...
  9. doi From blood pressure to physical disability: the role of cognition
    Merrill F Elias
    Department of Psychology, University of Maine, Orono, ME 04469 5742, USA
    Hypertension 55:1360-5. 2010
    ..Cognitive performance mediates between blood pressure and PA. As compared with systolic blood pressure, more domains of cognitive functioning intervene between diastolic blood pressure and PA...
  10. ncbi Lower cognitive function in the presence of obesity and hypertension: the Framingham heart study
    M F Elias
    Department of Mathematics and Statistics, Statistics and Consulting Unit, Boston University, MA 02215, USA
    Int J Obes Relat Metab Disord 27:260-8. 2003
    ..To determine the independent effects of obesity and hypertension on cognitive functioning...
  11. ncbi Framingham stroke risk profile and lowered cognitive performance
    Merrill F Elias
    Statistics and Consulting Unit, Department of Mathematics and Statistics, Boston University, Boston, MA 02215, USA
    Stroke 35:404-9. 2004
    ....
  12. ncbi New norms for a new generation: cognitive performance in the framingham offspring cohort
    Rhoda Au
    Department of Neurology, Boston University School of Medicine, Boston, Massachusetts 02118 2526, USA
    Exp Aging Res 30:333-58. 2004
    ..These findings suggest that continued surveillance of each generation is necessary to document the impact that unique social and economic variables have on cognitive function. Here, the authors provide updated normative data...
  13. ncbi Blood pressure and cognitive function in an African-American and a Caucasian-American sample: the Maine-Syracuse Study
    Michael A Robbins
    Department of Psychology, University of Maine, Orono, ME 04469 5742, USA
    Psychosom Med 67:707-14. 2005
    ..Corresponding data for the Caucasian-American MSLS participants were included to provide a basis for comparison. Interactions of age with BP indices were also assessed in relation to cognitive function...
  14. ncbi Cognitive performance and age: norms from the Maine-Syracuse Study
    Gregory A Dore
    Department of Psychology, University of Maine, Orono, Maine 04469 5742, USA
    Exp Aging Res 33:205-71. 2007
    ..Results are discussed in relation to findings for previous studies presenting normative data on cognitive ability as a function of age, education, and gender...
  15. ncbi Relation of obesity to cognitive function: importance of central obesity and synergistic influence of concomitant hypertension. The Framingham Heart Study
    Philip A Wolf
    Boston University School of Medicine, Boston, MA 02118 2526, USA
    Curr Alzheimer Res 4:111-6. 2007
    ..We hypothesized that mid-life obesity may modulate the impact of conventional cardiovascular risk factors (CVRF) on cognitive impairment. We tested this hypothesis in the community-based Framingham Offspring Study sample...
  16. ncbi Serum cholesterol and cognitive performance in the Framingham Heart Study
    Penelope K Elias
    Statistics and Consulting Unit, Department of Mathematics and Statistics, Boston University, 111 Cummington St, Boston, Massachusetts 02215, USA
    Psychosom Med 67:24-30. 2005
    ....
  17. ncbi Blood pressure-related cognitive decline: does age make a difference?
    Penelope K Elias
    Department of Psychology, University of Maine, Orono, ME 04469, USA
    Hypertension 44:631-6. 2004
    ..Young adults are as susceptible to blood pressure-related longitudinal decline in cognitive performance as are older adults...
  18. ncbi Homocysteine, type 2 diabetes mellitus, and cognitive performance: The Maine-Syracuse Study
    Michael A Robbins
    Department of Psychology, University of Maine, Orono, ME 04469 5742, USA
    Clin Chem Lab Med 43:1101-6. 2005
    ..Interactions between homocysteine concentrations and type 2 diabetes mellitus are observed such that associations between homocysteine and cognitive performance are stronger in the presence of diabetes...
  19. ncbi Managing and analysing data from a large-scale study on Framingham Offspring relating brain structure to cognitive function
    Joseph M Massaro
    Department of Biostatistics, Boston University School of Public Health, 715 Albany Street T3E, Boston, MA 02118, USA
    Stat Med 23:351-67. 2004
    ..We are currently performing analyses of data collected through 2002, and we discuss the statistical issues arising relating brain structure parameters to cognitive function...
  20. doi Relation between central adiposity and cognitive function in the Maine-Syracuse Study: attenuation by physical activity
    Gregory A Dore
    Department of Psychology, University of Maine, 5742 Little Hall, Orono, ME 04469 5742, USA
    Ann Behav Med 35:341-50. 2008
    ..However, only some of these studies have adjusted for cardiovascular risk factors and cardiovascular disease, and none have also adjusted for physical activity level...
  21. ncbi Introduction to the special section on health and cognitive function
    Shari R Waldstein
    Department of Psychology, University of Maryland, Baltimore County, and Geriatric Research Educational and Clinical Center, Baltimore Veterans Affairs Medical Center, Baltimore, MD 21250, USA
    Health Psychol 22:555-8. 2003
    ..Included in this special section are 6 empirical articles that examine the relation of health or disease to cognitive function...
  22. doi High-normal blood pressure and cognition: supplying the missing data
    Merrill F Elias
    Hypertension 52:e1-2; author reply e3. 2008
  23. doi Blood pressure and disability: first steps in future studies
    Michael A Robbins
    Hypertension 51:e25; author reply e26. 2008
  24. ncbi Blood pressure and disability: novus orsa
    Merrill F Elias
    Hypertension 50:1006-8. 2007

Research Grants12

  1. New CVD risk factors for lowered congitive functioning
    Merrill Elias; Fiscal Year: 2005
    ....
  2. AGE, RISK FACTORS FOR CVD AND COGNITIVE FUNCTIONING
    Merrill Elias; Fiscal Year: 2002
    ....
  3. Arterial stiffness, blood pressure and cognition
    Merrill Elias; Fiscal Year: 2009
    ....