The preclinical phase of alzheimer disease: A 22-year prospective study of the Framingham CohortM F Elias
Department of Mathematics and Statistics, Statistical Consulting Unit, 111 Cummington St, Boston University College of Arts and Sciences, Boston, MA 02215, USA
Arch Neurol 57:808-13. 2000
..To relate performance on tests of cognitive ability to the subsequent development of probable Alzheimer disease (pAD) and to identify the pattern of earliest changes in cognitive functioning associated with a diagnosis of pAD...
Chronic kidney disease, creatinine and cognitive functioningMerrill F Elias
Department of Psychology, Graduate School of Biomedical Sciences, University of Maine, Orono, ME, USA
Nephrol Dial Transplant 24:2446-52. 2009
..We examined the range of specific cognitive abilities affected by CKD and whether the associations of CKD with cognition were eliminated by statistical control for cardiovascular disease correlates of CKD...
Arterial pulse wave velocity and cognition with advancing ageMerrill F Elias
Department of Psychology and Graduate School of Biomedical Sciences, 5472 Little Hall, University of Maine, Orono, ME 04469, USA
Hypertension 53:668-73. 2009
..Early interventions to prevent an increase in arterial stiffness could possibly play an important role in the preservation of cognitive ability...
Homocysteine and cognitive performance: modification by the ApoE genotypeMerrill F Elias
Department of Psychology, University of Maine, Orono, ME 04469, USA
Neurosci Lett 430:64-9. 2008
..Presence of the ApoE-epsilon4 allele modifies the relation between plasma homocysteine and cognitive performance...
Left ventricular mass, blood pressure, and lowered cognitive performance in the Framingham offspringMerrill F Elias
Statistics and Consulting Unit, Department of Mathematics and Statistics, Boston University, Mass, USA
Hypertension 49:439-45. 2007
....
Homocysteine, folate, and vitamins B6 and B12 blood levels in relation to cognitive performance: the Maine-Syracuse studyMerrill F Elias
Department of Psychology, University of Maine, Orono, Maine, USA
Psychosom Med 68:547-54. 2006
....
Obesity, diabetes and cognitive deficit: The Framingham Heart StudyMerrill F Elias
Boston University, Department of Mathematics and Statistics, Statistics and Consulting Unit, 111 Cummington Street, Boston, MA 02215, USA
Neurobiol Aging 26:11-6. 2005
..To determine the independent effects of obesity on cognitive performance and to examine interactions between obesity and non-insulin dependent diabetes mellitus (NIDDM)...
Homocysteine and cognitive performance in the Framingham offspring study: age is importantMerrill F Elias
The Statistics and Consulting Unit, Department of Mathematics and Statistics, Boston University, Boston, MA, USA
Am J Epidemiol 162:644-53. 2005
..Early preventive interventions may be important, because the inverse association between tHcy and cognitive performance is observed beyond middle age...
From blood pressure to physical disability: the role of cognitionMerrill F Elias
Department of Psychology, University of Maine, Orono, ME 04469 5742, USA
Hypertension 55:1360-5. 2010
..Cognitive performance mediates between blood pressure and PA. As compared with systolic blood pressure, more domains of cognitive functioning intervene between diastolic blood pressure and PA...
Lower cognitive function in the presence of obesity and hypertension: the Framingham heart studyM F Elias
Department of Mathematics and Statistics, Statistics and Consulting Unit, Boston University, MA 02215, USA
Int J Obes Relat Metab Disord 27:260-8. 2003
..To determine the independent effects of obesity and hypertension on cognitive functioning...
Framingham stroke risk profile and lowered cognitive performanceMerrill F Elias
Statistics and Consulting Unit, Department of Mathematics and Statistics, Boston University, Boston, MA 02215, USA
Stroke 35:404-9. 2004
....
New norms for a new generation: cognitive performance in the framingham offspring cohortRhoda Au
Department of Neurology, Boston University School of Medicine, Boston, Massachusetts 02118 2526, USA
Exp Aging Res 30:333-58. 2004
..These findings suggest that continued surveillance of each generation is necessary to document the impact that unique social and economic variables have on cognitive function. Here, the authors provide updated normative data...
Blood pressure and cognitive function in an African-American and a Caucasian-American sample: the Maine-Syracuse StudyMichael A Robbins
Department of Psychology, University of Maine, Orono, ME 04469 5742, USA
Psychosom Med 67:707-14. 2005
..Corresponding data for the Caucasian-American MSLS participants were included to provide a basis for comparison. Interactions of age with BP indices were also assessed in relation to cognitive function...
Cognitive performance and age: norms from the Maine-Syracuse StudyGregory A Dore
Department of Psychology, University of Maine, Orono, Maine 04469 5742, USA
Exp Aging Res 33:205-71. 2007
..Results are discussed in relation to findings for previous studies presenting normative data on cognitive ability as a function of age, education, and gender...
Relation of obesity to cognitive function: importance of central obesity and synergistic influence of concomitant hypertension. The Framingham Heart StudyPhilip A Wolf
Boston University School of Medicine, Boston, MA 02118 2526, USA
Curr Alzheimer Res 4:111-6. 2007
..We hypothesized that mid-life obesity may modulate the impact of conventional cardiovascular risk factors (CVRF) on cognitive impairment. We tested this hypothesis in the community-based Framingham Offspring Study sample...
Serum cholesterol and cognitive performance in the Framingham Heart StudyPenelope K Elias
Statistics and Consulting Unit, Department of Mathematics and Statistics, Boston University, 111 Cummington St, Boston, Massachusetts 02215, USA
Psychosom Med 67:24-30. 2005
....
Blood pressure-related cognitive decline: does age make a difference?Penelope K Elias
Department of Psychology, University of Maine, Orono, ME 04469, USA
Hypertension 44:631-6. 2004
..Young adults are as susceptible to blood pressure-related longitudinal decline in cognitive performance as are older adults...
Homocysteine, type 2 diabetes mellitus, and cognitive performance: The Maine-Syracuse StudyMichael A Robbins
Department of Psychology, University of Maine, Orono, ME 04469-5742, USA
Clin Chem Lab Med 43:1101-6. 2005
..Interactions between homocysteine concentrations and type 2 diabetes mellitus are observed such that associations between homocysteine and cognitive performance are stronger in the presence of diabetes...
Managing and analysing data from a large-scale study on Framingham Offspring relating brain structure to cognitive functionJoseph M Massaro
Department of Biostatistics, Boston University School of Public Health, 715 Albany Street T3E, Boston, MA 02118, USA
Stat Med 23:351-67. 2004
..We are currently performing analyses of data collected through 2002, and we discuss the statistical issues arising relating brain structure parameters to cognitive function...
Relation between central adiposity and cognitive function in the Maine-Syracuse Study: attenuation by physical activityGregory A Dore
Department of Psychology, University of Maine, 5742 Little Hall, Orono, ME 04469 5742, USA
Ann Behav Med 35:341-50. 2008
..However, only some of these studies have adjusted for cardiovascular risk factors and cardiovascular disease, and none have also adjusted for physical activity level...
Introduction to the special section on health and cognitive functionShari R Waldstein
Department of Psychology, University of Maryland, Baltimore County, and Geriatric Research Educational and Clinical Center, Baltimore Veterans Affairs Medical Center, Baltimore, MD 21250, USA
Health Psychol 22:555-8. 2003
..Included in this special section are 6 empirical articles that examine the relation of health or disease to cognitive function...
High-normal blood pressure and cognition: supplying the missing dataMerrill F Elias
Hypertension 52:e1-2; author reply e3. 2008
Blood pressure and disability: first steps in future studiesMichael A Robbins
Hypertension 51:e25; author reply e26. 2008
Blood pressure and disability: novus orsaMerrill F Elias
Hypertension 50:1006-8. 2007