Onychomycosis: pathogenesis, diagnosis, and managementB E Elewski
Department of Dermatology, University Hospitals of Cleveland, Case Western Reserve University, Ohio, USA
Clin Microbiol Rev 11:415-29. 1998
..In addition, the short treatment times (< 3 months) and intermittent dosing schedules are likely to enhance compliance and reduce the costs of therapy...
Modification of the Nail Psoriasis Severity IndexCharles A Parrish
J Am Acad Dermatol 53:745-6; author reply 746-7. 2005
- Efficacy and safety of a new once-daily topical ketoconazole 2% gel in the treatment of seborrheic dermatitis: a phase III trial
Boni Elewski
University of Alabama at Birmingham, Birmingham, AL 35294, USA
J Drugs Dermatol 5:646-50. 2006
..The first gel formulation of ketoconazole has been tested in 2-week treatment courses...
- The prevalence of acne in adults 20 years and older
Christin N Collier
School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294 0009, USA
J Am Acad Dermatol 58:56-9. 2008
..However, a significant number of patients either continue to experience acne or develop new-onset acne after the teenaged years...
Onychomycosis and diabetesS Cathcart
Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA
J Eur Acad Dermatol Venereol 23:1119-22. 2009
..This study aims to discuss factors specific to diabetics in the diagnosis and treatment of onychomycosis...
- Efinaconazole 10% solution in the treatment of toenail onychomycosis: Two phase III multicenter, randomized, double-blind studies
Boni E Elewski
Department of Dermatology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama 35294 0009, USA
J Am Acad Dermatol 68:600-8. 2013
..Topical lacquer treatments have negligible efficacy. Oral treatments, although more efficacious, are limited by drug interactions and potential hepatotoxicity...
- An investigator-blind, randomized, 4-week, parallel-group, multicenter pilot study to compare the safety and efficacy of a nonsteroidal cream (Promiseb Topical Cream) and desonide cream 0.05% in the twice-daily treatment of mild to moderate seborrheic der
Boni Elewski
Department of Dermatology, University of Alabama at Birmingham School of Medicine, Ste 414, 700 18th St S, Birmingham, AL 35233 3805, USA
Clin Dermatol 27:S48-53. 2009
..0173). Investigator global assessments of improvement found both study agents were essentially the same, and participants in both groups achieved clinically important improvement...
- The use of 40% urea cream in the treatment of moccasin tinea pedis
Boni E Elewski
Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294 0009, USA
Cutis 73:355-7. 2004
..After 2 to 3 weeks, a 100% cure rate was achieved in the 12 patients treated with topical 40% urea cream and ciclopirox cream concomitantly...
- Clinical diagnosis of common scalp disorders
Boni E Elewski
Department of Dermatology, University of Alabama, Birmingham, AL 35294, USA
J Investig Dermatol Symp Proc 10:190-3. 2005
..Diagnostic techniques and effective treatment strategies for each of the above conditions will be discussed...
- Results of a national rosacea patient survey: common issues that concern rosacea sufferers
Boni E Elewski
Department of Dermatology, University of Alabama School of Medicine at Birmingham, AL 35233, USA
J Drugs Dermatol 8:120-3. 2009
..Of those respondents who discussed rosacea with their physician, 83% agreed that their physician influences their use of medication; 61% viewed their physician-in most cases a dermatologist-as a partner in managing their rosacea...
- Terbinafine hydrochloride oral granules versus oral griseofulvin suspension in children with tinea capitis: results of two randomized, investigator-blinded, multicenter, international, controlled trials
Boni E Elewski
Department of Dermatology, University of Alabama, Birmingham, Alabama 35294 0009, USA
J Am Acad Dermatol 59:41-54. 2008
..Alternative antifungal therapies with shorter/simpler treatment regimens may be important to develop for this indication...
- Comparison of clinical and pharmacokinetic profiles of etanercept 25 mg twice weekly and 50 mg once weekly in patients with psoriasis
B Elewski
Uniuversity of Alabama at Birmingham, 700 18th Street S, Birmingham, AL 35233, USA
Br J Dermatol 156:138-42. 2007
..Etanercept is a tumour necrosis factor antagonist that is approved in the U.S.A., Canada and Europe for treating adult patients with chronic moderate to severe plaque psoriasis...
- Percutaneous absorption kinetics of topical metronidazole formulations in vitro in the human cadaver skin model
Boni E Elewski
Department of Dermatology, University of Alabama School of Medicine, Birmingham, AL 35294 0009, USA
Adv Ther 24:239-46. 2007
..Additional studies are warranted to examine absorption of metronidazole into the relevant target zone and the correlation of absorption with efficacy...
- A comparison of 15% azelaic acid gel and 0.75% metronidazole gel in the topical treatment of papulopustular rosacea: results of a randomized trial
Boni E Elewski
Department of Dermatology, University of Alabama at Birmingham, 35233, USA
Arch Dermatol 139:1444-50. 2003
..75% metronidazole gel (MetroGel; Galderma Laboratories LP, Fort Worth, Tex) as topical therapy for moderate, papulopustular facial rosacea...
- A novel foam formulation of ketoconazole 2% for the treatment of seborrheic dermatitis on multiple body regions
Boni E Elewski
University of Alabama at Birmingham, Birmingham, AL 35294, USA
J Drugs Dermatol 6:1001-8. 2007
..A novel topical foam formulation of ketoconazole has been developed for use on the scalp, body, and face...
- Tinea capitis: a current perspective
B E Elewski
Department of Dermatology, University of Alabama, Birmingham 35233, USA
J Am Acad Dermatol 42:1-20; quiz 21-4. 2000
....
- Onychomycosis. Treatment, quality of life, and economic issues
B E Elewski
Department of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, USA
Am J Clin Dermatol 1:19-26. 2000
..The drug aquisition cost of fluconazole given as a 300 mg dose once weekly for 6 months is $US562.76 and given as a 150 mg dose once weekly (for 6 months) $US281.38...
- An open-label study of the safety and efficacy of sertaconazole nitrate in the treatment of seborrheic dermatitis
Boni E Elewski
University of Alabama, Birmingham, Alabama, USA
J Drugs Dermatol 10:895-9. 2011
..To demonstrate the efficacy and evaluate the safety of sertaconazole nitrate cream 2% in the treatment of seborrheic dermatitis (SD)...
- Azelaic acid gel 15%: clinical versatility in the treatment of rosacea
James Q Del Rosso
Department of Dermatology, University of Nevada School of Medicine, Las Vegas, USA
Cutis 78:6-19. 2006
..In a roundtable discussion, information leaders discussed the pathophysiology of rosacea and other issues of importance to successful rosacea management, such as skin care regimens, quality of life (QOL), and compliance...
- Cutaneous fungal infections in the elderly
Elizabeth S Martin
Department of Dermatology, University of Alabama, Birmingham, USA
Clin Geriatr Med 18:59-75. 2002
..In the elderly patient, unique challenges may exist in the diagnosis and treatment of these diseases. However, proper therapy for these prevalent conditions leads to a better quality of life...
- Tinea capitis in adult women masquerading as bacterial pyoderma
Elizabeth S Martin
Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
J Am Acad Dermatol 49:S177-9. 2003
..A biopsy specimen was helpful in making the diagnosis in 2 of the 3 patients, but fungal culture confirmed the diagnosis in all cases...
- Rosacea - global diversity and optimized outcome: proposed international consensus from the Rosacea International Expert Group
B E Elewski
Department of Dermatology, University of Alabama, Birmingham, AL, USA
J Eur Acad Dermatol Venereol 25:188-200. 2011
....
- Rosacea: a review of current topical, systemic and light-based therapies
C Kennedy Carney
Department of Dermatology, University of Alabama at Birmingham, Birmingham AL, USA
G Ital Dermatol Venereol 144:673-88. 2009
..As our knowledge of rosacea and its therapeutic options expand, a multifaceted approach to treatment is warranted...
- Safe and effective treatment of seborrheic dermatitis
Boni E Elewski
University of Alabama, Birmingham, USA
Cutis 83:333-8. 2009
..Antifungal therapy is considered primary, but some agents are more effective than others because of their favorable pharmacokinetic profiles, high rates of absorption, anti-inflammatory and antipruritic properties, and vehicle...
- Advances in topical and systemic antifungals
Alexandra Y Zhang
Department of Dermatology, University of Alabama at Birmingham, EFH 414, 1530 3rd Avenue South, Birmingham, AL 35294, USA
Dermatol Clin 25:165-83, vi. 2007
..Several new antifungal agents have demonstrated significant therapeutic benefits and have broadened clinicians' choices in the treatment of superficial and systemic invasive fungal infections...
- A randomized controlled trial assessing the efficacy of fluconazole in the treatment of pediatric tinea capitis
K Wade Foster
Department of Dermatology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama 35294-0009, USA
J Am Acad Dermatol 53:798-809. 2005
..The outcomes observed in this trial highlight the need to more clearly define the relative importance of adjunctive topical therapies and the evaluation and treatment of infected contacts as factors affecting cure rates...
- Reactivity to trichophytin antigen in patients with onychomycosis: effect of terbinafine
Boni E Elewski
Department of Dermatology, University Hospitals of Cleveland, Cleveland, Ohio, USA
J Am Acad Dermatol 46:371-5. 2002
..Many patients with chronic dermatophytosis and onychomycosis have depressed cell-mediated immunity (CMI) to trichophytin...
- Extrafacial and generalized granulomatous periorificial dermatitis
Amy J Urbatsch
Department of Dermatology, University of Alabama at Birmingham, 35233, USA
Arch Dermatol 138:1354-8. 2002
..The condition is self-limiting and is not associated with systemic involvement...
- The safety and efficacy of high-dose alefacept compared with a loading dose of alefacept in patients with chronic plaque psoriasis
Jennifer A Cafardi
Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA
Skinmed 7:67-72. 2008
..Two separate dosing regimens are evaluated in this study: 30 mg IM for 6 weeks followed by 15 mg IM for 6 weeks (group 1) and alefacept 30 mg IM weekly for 12 weeks (group 2)...
- International summit on cutaneous antifungal therapy, focus on tinea capitis, Boston, Massachusetts, November 11-13, 1994
B E Elewski
Department of Dermatology, University Hospitals of Cleveland, Ohio, USA
Pediatr Dermatol 13:69-77. 1996
..Some of the key points pertaining to the epidemiology, etiology, pathogenesis, presentation, and management of tinea capitis are discussed...
- Alefacept in the treatment of psoriatic nail disease: a proof of concept study
Charles A Parrish
Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
J Drugs Dermatol 5:339-40. 2006
..We present the results of a prospective, open-label, proof of concept study to determine the efficacy and safety of alefacept in subjects with moderate to severe nail psoriasis...
- Epidemiologic surveillance of cutaneous fungal infection in the United States from 1999 to 2002
K Wade Foster
Department of Dermatology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA
J Am Acad Dermatol 50:748-52. 2004
..CONCLUSION: Consideration of the current epidemiologic trends in the incidence of cutaneous fungal pathogens is of key importance to investigational efforts, diagnosis, and treatment...
- Office practice-based confirmation of onychomycosis: a US nationwide prospective survey
Boni E Elewski
Department of Dermatology, University of Alabama, Birmingham, AL 35294, USA
Arch Intern Med 162:2133-8. 2002
....
- Clinical response in psoriasis patients discontinued from and then reinitiated on etanercept therapy
Kenneth B Gordon
Loyola University, Maywood, IL, USA
J Dermatolog Treat 17:9-17. 2006
....
- Intermittent versus continuous terbinafine in the treatment of toenail onychomycosis: a randomized, double-blind comparison
Bardur Sigurgeirsson
Department of Dermatology, University of Iceland, Reykjavik, Iceland
J Dermatolog Treat 17:38-44. 2006
..Terbinafine is an established drug for the treatment of toenail onychomycosis. Minimizing the total dose of terbinafine and giving it intermittently could improve tolerability as well as compliance, provided efficacy is not compromised...
- Rosacea trial comparing twice-daily azelaic acid gel 15% with once-daily metronidazole gel 1%
Boni E Elewski
Cutis 79:57-8; author reply 58. 2007
- In reference to the October 2004 comprehensive overview of rosacea therapy
Boni E Elewski
J Am Acad Dermatol 57:728. 2007
- Onychotillomania: 2 case reports
Marc Inglese
University of Florida, Gainesville, USA
Cutis 73:171-4. 2004
..Onychotillomania may be a form of obsessive-compulsive disorder (OCD), and we discuss the psychologic factors and current treatments for this condition...
- Infliximab for the treatment of severe pustular psoriasis
Boni E Elewski
J Am Acad Dermatol 47:796-7. 2002
