Hashem B El-Serag

Summary

Publications

  1. ncbi request reprint Hepatocellular carcinoma: an epidemiologic view
    Hashem B El-Serag
    Section of Gastroenterology and Health Services Research at the Houston Department of Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
    J Clin Gastroenterol 35:S72-8. 2002
  2. ncbi request reprint Survival in hepatitis C and HIV co-infection: a cohort study of hospitalized veterans
    Hashem B El-Serag
    Houston Center for Quality of Care and Utilization Studies, Houston Veterans Affairs Medical Center, Baylor College of Medicine, Houston, Texas, USA
    Clin Gastroenterol Hepatol 3:175-83. 2005
  3. doi request reprint Importance of patient, provider, and facility predictors of hepatitis C virus treatment in veterans: a national study
    Jennifer R Kramer
    Houston VA Health Services Research and Development Center of Excellence, Michael E DeBakey Veterans Affairs Medical Center, Houston, Texas 77030, USA
    Am J Gastroenterol 106:483-91. 2011
  4. pmc A new laboratory-based algorithm to predict development of hepatocellular carcinoma in patients with hepatitis C and cirrhosis
    Hashem B El-Serag
    Section of Gastroenterology and Hepatology, Michael E DeBakey VA Medical Center, Houston, Texas Houston VA Health Services Research and Development Service Center of Excellence, Michael E DeBakey VA Medical Center, Houston, Texas Baylor College of Medicine, Houston, Texas Electronic address
    Gastroenterology 146:1249-55.e1. 2014
  5. pmc Referral and receipt of treatment for hepatocellular carcinoma in United States veterans: effect of patient and nonpatient factors
    Jessica A Davila
    Houston VA Health Services Research Center of Excellence, Section of Health Services Research, Michael E DeBakey Veterans Affairs Medical Center, Houston, TX, USA
    Hepatology 57:1858-68. 2013
  6. pmc Barrett's esophagus suspected at endoscopy but no specialized intestinal metaplasia on biopsy, what's next?
    Hashim E Khandwalla
    Sections of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA
    Am J Gastroenterol 109:178-82. 2014
  7. pmc Oral bisphosphonates and the risk of Barrett's esophagus: case-control analysis of US veterans
    Derek Lin
    Department of Medicine, Michael E DeBakey Veterans Affairs Medical Center, Houston, Texas, USA
    Am J Gastroenterol 108:1576-83. 2013
  8. ncbi request reprint Is the length of newly diagnosed Barrett's esophagus decreasing? The experience of a VA Health Care System
    Hashem B El-Serag
    Section of Gastroenterology, Houston VA Medical Center, and Baylor College of Medicine, Texas 77030, USA
    Clin Gastroenterol Hepatol 2:296-300. 2004
  9. ncbi request reprint The prevalence of suspected Barrett's esophagus in children and adolescents: a multicenter endoscopic study
    Hashem B El-Serag
    The Michael E DeBakey Veterans Affairs Medical Center 152, 2002 Holcombe Blvd, Houston, TX 77030, USA
    Gastrointest Endosc 64:671-5. 2006
  10. ncbi request reprint Association between facility characteristics and the process of care delivered to patients with hepatitis C virus infection
    Fasiha Kanwal
    Houston VA HSR and D Center of Excellence, Health Services Research and Development Service, Michael E DeBakey Veterans Affairs Medical Center, 2002 Holcombe Blvd, Houston, TX, 77030, USA
    Dig Dis Sci 59:273-81. 2014

Detail Information

Publications121 found, 100 shown here

  1. ncbi request reprint Hepatocellular carcinoma: an epidemiologic view
    Hashem B El-Serag
    Section of Gastroenterology and Health Services Research at the Houston Department of Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
    J Clin Gastroenterol 35:S72-8. 2002
    ..The future incidence trends of HCC will be determined to a large extent by the clinical course of HCV-infected people...
  2. ncbi request reprint Survival in hepatitis C and HIV co-infection: a cohort study of hospitalized veterans
    Hashem B El-Serag
    Houston Center for Quality of Care and Utilization Studies, Houston Veterans Affairs Medical Center, Baylor College of Medicine, Houston, Texas, USA
    Clin Gastroenterol Hepatol 3:175-83. 2005
    ..However, the long-term effect of hepatitis C virus (HCV) co-infection on the mortality of HIV-infected patients remains unclear...
  3. doi request reprint Importance of patient, provider, and facility predictors of hepatitis C virus treatment in veterans: a national study
    Jennifer R Kramer
    Houston VA Health Services Research and Development Center of Excellence, Michael E DeBakey Veterans Affairs Medical Center, Houston, Texas 77030, USA
    Am J Gastroenterol 106:483-91. 2011
    ..Several patient characteristics are known to impact hepatitis C virus (HCV) antiviral treatment rates. However, it is unclear whether, and to what extent, health-care providers or facility characteristics impact HCV treatment rates...
  4. pmc A new laboratory-based algorithm to predict development of hepatocellular carcinoma in patients with hepatitis C and cirrhosis
    Hashem B El-Serag
    Section of Gastroenterology and Hepatology, Michael E DeBakey VA Medical Center, Houston, Texas Houston VA Health Services Research and Development Service Center of Excellence, Michael E DeBakey VA Medical Center, Houston, Texas Baylor College of Medicine, Houston, Texas Electronic address
    Gastroenterology 146:1249-55.e1. 2014
    ..We constructed an AFP-based algorithm that included these factors to identify patients at risk for HCC, and tested its predictive ability in a large set of patients with cirrhosis...
  5. pmc Referral and receipt of treatment for hepatocellular carcinoma in United States veterans: effect of patient and nonpatient factors
    Jessica A Davila
    Houston VA Health Services Research Center of Excellence, Section of Health Services Research, Michael E DeBakey Veterans Affairs Medical Center, Houston, TX, USA
    Hepatology 57:1858-68. 2013
    ..Only receipt of HCC surveillance was associated with increased likelihood of outpatient diagnosis, being seen by a surgeon or oncologist, and treatment...
  6. pmc Barrett's esophagus suspected at endoscopy but no specialized intestinal metaplasia on biopsy, what's next?
    Hashim E Khandwalla
    Sections of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA
    Am J Gastroenterol 109:178-82. 2014
    ..The aim of this study was to examine the value of endoscopic follow-up for individuals with endoscopic only BE at index endoscopy...
  7. pmc Oral bisphosphonates and the risk of Barrett's esophagus: case-control analysis of US veterans
    Derek Lin
    Department of Medicine, Michael E DeBakey Veterans Affairs Medical Center, Houston, Texas, USA
    Am J Gastroenterol 108:1576-83. 2013
    ..This study examined Barrett's esophagus (BE) risk factors in veterans to determine the association between risk of BE and use of oral bisphosphonates...
  8. ncbi request reprint Is the length of newly diagnosed Barrett's esophagus decreasing? The experience of a VA Health Care System
    Hashem B El-Serag
    Section of Gastroenterology, Houston VA Medical Center, and Baylor College of Medicine, Texas 77030, USA
    Clin Gastroenterol Hepatol 2:296-300. 2004
    ..Secular trends in the length of newly diagnosed Barrett's esophagus (BE) are unknown. We have anecdotally noticed less frequent new diagnoses of long segments of BE...
  9. ncbi request reprint The prevalence of suspected Barrett's esophagus in children and adolescents: a multicenter endoscopic study
    Hashem B El-Serag
    The Michael E DeBakey Veterans Affairs Medical Center 152, 2002 Holcombe Blvd, Houston, TX 77030, USA
    Gastrointest Endosc 64:671-5. 2006
    ..The prevalence of Barrett's esophagus (BE) in young individuals is unclear...
  10. ncbi request reprint Association between facility characteristics and the process of care delivered to patients with hepatitis C virus infection
    Fasiha Kanwal
    Houston VA HSR and D Center of Excellence, Health Services Research and Development Service, Michael E DeBakey Veterans Affairs Medical Center, 2002 Holcombe Blvd, Houston, TX, 77030, USA
    Dig Dis Sci 59:273-81. 2014
    ..However, the solutions to these problems are less obvious. Healthcare facility factors are potentially modifiable and may enhance process quality in HCV treatment...
  11. pmc Prevalence and predictors of hepatitis B virus coinfection in a United States cohort of hepatitis C virus-infected patients
    Gia L Tyson
    Houston VA Health Services Research and Development Center of Excellence, Michael E DeBakey Veterans Affairs Medical Center, Houston, TX, USA
    Hepatology 58:538-45. 2013
    ..S. on the prevalence of HBV coinfection in HCV patients. Among veterans with HCV, exposure to HBV is common (~35%), but HBV coinfection is relatively low (1.4%). Several possible risk factors were identified...
  12. ncbi request reprint Risk factors for intrahepatic and extrahepatic cholangiocarcinoma: a hospital-based case-control study
    Yasser H Shaib
    The Houston Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas, USA
    Am J Gastroenterol 102:1016-21. 2007
    ..We evaluated hepatitis C virus (HCV), hepatitis B virus (HBV), and liver cirrhosis as risk factors for intrahepatic cholangiocarcinoma (ICC) and extrahepatic cholangiocarcinoma (ECC)...
  13. ncbi request reprint The continuing increase in the incidence of hepatocellular carcinoma in the United States: an update
    Hashem B El-Serag
    The Houston Center for Quality of Care and Utilization Studies, Sections of Gastroenterology and Health Services Research at The Houston Veterans Affairs Medical Center, and Baylor College of Medicine, Houston, Texas 77030, USA
    Ann Intern Med 139:817-23. 2003
    ..The incidence of hepatocellular carcinoma was reported to be increasing in the United States. However, alternate explanations were diagnostic or reclassification bias and changes in the demographic features of the general population...
  14. pmc Patient-centered, comparative effectiveness of esophageal cancer screening: protocol for a comparative effectiveness research study to inform guidelines for evidence-based approach to screening and surveillance endoscopy
    Jennifer R Kramer
    Houston VA HSR and D Center of Excellence, Michael E, DeBakey Veterans Affairs Medical Center, Houston, TX, USA
    BMC Health Serv Res 12:288. 2012
    ..Therefore, it is imperative to establish the CE and acceptability about the risks and outcomes related to these practices to better inform expert recommendations and provider-patient decisions...
  15. ncbi request reprint Gastroesophageal reflux among different racial groups in the United States
    Hashem B El-Serag
    Section of Gastroenterology, Houston Department of Veterans Affairs Medical Center 152, 2002 Holcombe Boulevard, Houston, TX 77030, USA
    Gastroenterology 126:1692-9. 2004
    ..It remains unknown whether this racial discrepancy reflects a higher prevalence of gastroesophageal reflux disease (GERD) symptoms or a higher degree of esophageal damage...
  16. pmc Utilization and outcomes of palliative therapy for hepatocellular carcinoma: a population-based study in the United States
    Jessica A Davila
    Section of Health Services Research, Houston Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX, USA
    J Clin Gastroenterol 46:71-7. 2012
    ..To evaluate the utilization and determinants of receiving palliative treatment for hepatocellular carcinoma (HCC), and its effect on survival...
  17. ncbi request reprint Cirrhosis and hepatocellular carcinoma in HIV-infected veterans with and without the hepatitis C virus: a cohort study, 1992-2001
    Thomas P Giordano
    Houston Center for Quality of Care and Utilization Studies, Health Services Research and Development Service, Department of Veterans Affairs Medical Center, Houston, Tex 77030, USA
    Arch Intern Med 164:2349-54. 2004
    ....
  18. ncbi request reprint Prevalence and determinants of histological abnormalities of the gastric cardia in volunteers
    Hashem B El-Serag
    Section of Gastroenterology, Houston Department of Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas, USA
    Scand J Gastroenterol 42:1158-66. 2007
    ..There have been no studies on non-patient populations. The aim of this study was to mitigate the potential effects of selection bias...
  19. ncbi request reprint Endoscopic and surgical therapy for intrahepatic cholangiocarcinoma in the united states: a population-based study
    Yasser H Shaib
    Sections of Health Services, Houston, TX, USA
    J Clin Gastroenterol 41:911-7. 2007
    ..Intrahepatic cholangiocarcinoma (ICC) is a highly fatal disease with limited therapeutic options. The determinants, trends, and outcomes of different therapies for ICC are largely unknown in the United States...
  20. pmc Racial differences in the association between adiposity measures and the risk of hepatitis C-related liver disease
    Donna L White
    Clinical Epidemiology and Outcomes Program, Houston VA Health Services Research and Development Center of Excellence, Michael E DeBakey Veterans Affairs Medical Center, Houston, TX 77030, USA
    J Clin Gastroenterol 46:779-88. 2012
    ..It is unknown whether relative differences in the distribution of adipose tissue, lean mass, and other anthropometric measurements may explain these observed interethnic differences in disease risk...
  21. ncbi request reprint Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma
    Hashem B El-Serag
    Section of Gastroenterology, Houston Departmentof Veterans Affais Medical Center and Baylor College of Medicine, Houston, TX 77030, USA
    Gastroenterology 126:460-8. 2004
    ..An association between diabetes and chronic liver disease has been reported. However, the temporal relationship between these conditions remains unknown...
  22. doi request reprint Utilization of surveillance for hepatocellular carcinoma among hepatitis C virus-infected veterans in the United States
    Jessica A Davila
    the Michael E DeBakey Veterans Affairs Medical Center, Baylor College of Medicine, Houston, Texas, USA
    Ann Intern Med 154:85-93. 2011
    ..Surveillance for hepatocellular carcinoma (HCC) is recommended for patients with hepatitis C virus (HCV) infection and cirrhosis. However, whether surveillance is being done as recommended is unknown...
  23. pmc Hepatocellular carcinoma screening practices in the Department of Veterans Affairs: findings from a national facility survey
    Hashem B El-Serag
    Houston HSR and D Center of Excellence, Michael E DeBakey Veterans Affairs Medical Center, 2002 Holcombe Blvd 152, Houston, TX, 77030, USA
    Dig Dis Sci 58:3117-26. 2013
    ..Previous studies suggest low rates of hepatocellular carcinoma (HCC) screening in clinical practice. There is little information on the provider- and healthcare-facility-related factors that explain the use of HCC screening...
  24. pmc Waist-to-hip ratio, but not body mass index, is associated with an increased risk of Barrett's esophagus in white men
    Jennifer R Kramer
    Houston VA Health Services Research and Development Center of Excellence, Houston, Texas 77030, USA
    Clin Gastroenterol Hepatol 11:373-381.e1. 2013
    ..We examined the effects of waist-to-hip ratio (WHR) and body mass index (BMI) on the risk of BE and investigated whether race, GERD symptoms, or hiatus hernia were involved...
  25. doi request reprint Incidence and survival of colorectal cancer among Hispanics in the United States: a population-based study
    Nadim S Jafri
    Section of Gastroenterology, The Michael E DeBakey VA Medical Center and Baylor College of Medicine, Houston, TX, USA
    Dig Dis Sci 58:2052-60. 2013
    ..Hispanics are the largest and fastest growing ethnic group in the United States (US)...
  26. pmc Helicobacter pylori-negative gastritis: prevalence and risk factors
    Helena Nordenstedt
    Houston VA HSR and D Center of Excellence, Houston, TX, USA
    Am J Gastroenterol 108:65-71. 2013
    ..The objective of this study was to investigate the prevalence of H. pylori among individuals with histologic gastritis...
  27. ncbi request reprint Obesity and disease of the esophagus and colon
    Hashem B El-Serag
    Section of Gastroenterology, Michael E DeBakey Veterans Affairs Medical Center at Baylor College of Medicine, 2002 Holcombe Boulevard, Houston, TX 77030, USA
    Gastroenterol Clin North Am 34:63-82. 2005
    ..This article discusses the evidence linking obesity to the different manifestations of gastroesophageal reflux disease and colorectal cancer...
  28. pmc Is there a race-based disparity in the survival of veterans with HIV?
    Thomas P Giordano
    Department of Medicine, Baylor College of Medicine, Houston, TX, USA
    J Gen Intern Med 21:613-7. 2006
    ..Disparities in survival for black patients with HIV in the United States have been reported. The VA is an equal access health care system...
  29. ncbi request reprint National adherence to evidence-based guidelines for the prescription of nonsteroidal anti-inflammatory drugs
    Neena S Abraham
    Houston Center for Quality of Care and Utilization Studies, Michael E DeBakey Veterans Affairs Medical Center, Texas 77030, USA
    Gastroenterology 129:1171-8. 2005
    ..Our objective was to assess adherence to evidence-based guidelines by providers of the Department of Veterans Affairs nationwide...
  30. doi request reprint Surveillance for hepatocellular carcinoma: development and validation of an algorithm to classify tests in administrative and laboratory data
    Peter Richardson
    Section of Health Services Research, Houston Center for Quality of Care and Utilization Studies, The Houston Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX, USA
    Dig Dis Sci 55:3241-51. 2010
    ..The purpose of alpha-fetoprotein (AFP) and abdominal ultrasound (US) cannot be discerned in administrative data...
  31. ncbi request reprint The epidemic of esophageal adenocarcinoma
    Hashem B El-Serag
    Sections of Gastroenterology and Health Services Research, Houston Veterans Affairs Medical Center, Baylor College of Medicine, Houston, TX, USA
    Gastroenterol Clin North Am 31:421-40, viii. 2002
    ....
  32. ncbi request reprint Hepatitis C coinfection increases the risk of fulminant hepatic failure in patients with HIV in the HAART era
    Jennifer R Kramer
    Houston Center for Quality of Care and Utilization Studies, Health Services Research and Development Service, Michael E DeBakey Veterans Affairs Medical Center 152, Houston, TX 77030, USA
    J Hepatol 42:309-14. 2005
    ..It is uncertain if patients coinfected with hepatitis C and HIV are more likely to suffer fulminant hepatic failure (FHF) when compared to patients with HIV-only...
  33. pmc Risk of hepatobiliary and pancreatic cancers after hepatitis C virus infection: A population-based study of U.S. veterans
    Hashem B El-Serag
    Department of Medicine, Baylor College of Medicine, Houston, TX, USA
    Hepatology 49:116-23. 2009
    ..Absence of an association with ECC was consistent in adjusted and unadjusted models. A significant association with pancreatic cancer was erased by alcohol use and other variables...
  34. ncbi request reprint Treatment and outcomes of treating of hepatocellular carcinoma among Medicare recipients in the United States: a population-based study
    Hashem B El-Serag
    Section of Health Services Research, Houston Veterans Affairs Medical Center, Baylor College of Medicine, 2002 Holcombe Boulevard 152, Houston, TX 77030, USA
    J Hepatol 44:158-66. 2006
    ..Yet, neither the extent to which potentially curative or palliative therapy is used to treat HCC, nor the determinants of using such therapies are known. Further, it is unclear how effective different modalities are for treating HCC...
  35. ncbi request reprint The effect of HIV coinfection on the risk of cirrhosis and hepatocellular carcinoma in U.S. veterans with hepatitis C
    Jennifer R Kramer
    Houston Center for Quality of Care and Utilization Studies, Health Services Research and Development Service, Michael E DeBakey Veterans Affairs Medical Center, Houston, TX 77030, USA
    Am J Gastroenterol 100:56-63. 2005
    ..This study was conducted to determine whether HIV coinfection increases the risk of cirrhosis in HCV-infected patients in the HAART and pre-HAART eras. Further, the risk of hepatocellular carcinoma was also examined...
  36. ncbi request reprint Hepatocellular carcinoma: epidemiology and molecular carcinogenesis
    Hashem B El-Serag
    Michael E DeBakey Veterans Administration Medical Center and Baylor College of Medicine, Houston Center for Quality of Care and Utilization Studies, Houston, Texas, USA
    Gastroenterology 132:2557-76. 2007
    ..A detailed understanding of epidemiologic factors and molecular mechanisms associated with HCC ultimately could improve our current concepts for screening and treatment of this disease...
  37. ncbi request reprint Determinants of gastroesophageal reflux disease in adults with a history of childhood gastroesophageal reflux disease
    Hashem B El-Serag
    Section of Health Services Research, Michael E DeBakey Veterans Affairs Medical Center, Houston, Texas 77030, USA
    Clin Gastroenterol Hepatol 5:696-701. 2007
    ..We conducted a nested case-control study to examine the prevalence and risk factors for current gastroesophageal reflux disease (GERD) symptoms in young adults with a history of childhood GERD...
  38. pmc Visceral abdominal obesity measured by CT scan is associated with an increased risk of Barrett's oesophagus: a case-control study
    Hashem B El-Serag
    Houston VA HSR and D Center of Excellence Section, Michael E DeBakey VA Medical Center and Baylor College of Medicine, Houston, Texas, USA
    Gut 63:220-9. 2014
    ..We examined the association between visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) and the risk of BE...
  39. pmc The incidence and prevalence of inflammatory bowel disease among U.S. veterans: a national cohort study
    Jason K Hou
    Houston VA HSR and D Center of Excellence, Michael E DeBakey Veterans Affairs Medical Center, Houston, Texas, USA
    Inflamm Bowel Dis 19:1059-64. 2013
    ..The aim of this study was to identify temporal trends in the incidence and prevalence of CD and UC among VA users using national VA data sets...
  40. ncbi request reprint Secular trends in the use, quality, and outcomes of gastrectomy for noncardia gastric cancer in the United States
    Anne Le
    Department of Surgery, Baylor College of Medicine and Michael E DeBakey VA Medical Center, Houston, Texas, USA
    Ann Surg Oncol 14:2519-27. 2007
    ..We examined the trends, extent, and determinants of surgical treatment and the influence of gastrectomy and adequacy of lymphadenectomy (defined as collection of 15 or more lymph nodes) on non-cardia gastric cancer survival...
  41. doi request reprint Finasteride and methadone use and risk of advanced hepatitis C related liver disease
    Donna L White
    Clinical Epidemiology and Outcomes Program, Houston VA Health Services Research and Development Center of Excellence, Michael E DeBakey Veteran Affairs Medical Center, Houston, TX, USA
    Dig Dis Sci 57:3004-10. 2012
    ..We evaluated the association between two medications that alter bioavailable androgen levels, finasteride and methadone, and risk of advanced HCV-related liver disease...
  42. pmc Determinants of serum alpha-fetoprotein levels in hepatitis C-infected patients
    Peter Richardson
    Houston Center for Quality of Care and Utilization Studies, Houston, Texas, USA
    Clin Gastroenterol Hepatol 10:428-33. 2012
    ..This information might improve AFP-based algorithms for HCC detection...
  43. ncbi request reprint Fundoplication and the risk of esophageal cancer in gastroesophageal reflux disease: a Veterans Affairs cohort study
    Thomas Tran
    Department of Medicine, Baylor College of Medicine, Houston, Texas, USA
    Am J Gastroenterol 100:1002-8. 2005
    ..It has been proposed that fundoplication can reduce the risk of esophageal cancer in patients with gastroesophageal reflux disease (GERD). In this cohort study, we assessed the effect of fundoplication on the incidence of esophageal cancer...
  44. pmc Use of surveillance for hepatocellular carcinoma among patients with cirrhosis in the United States
    Jessica A Davila
    Section of Health Services Research, Houston Center for Quality of Care and Utilization Studies, Houston VA Medical Center and Baylor College of Medicine, Houston, TX, USA
    Hepatology 52:132-41. 2010
    ..5-fold and 2.8-fold, respectively, more likely to receive regular surveillance than those seen by a primary care physician only. Geographic variation in surveillance was observed and explained by patient and physician factors...
  45. ncbi request reprint Prevention of complicated ulcer disease among chronic users of nonsteroidal anti-inflammatory drugs: the use of a nomogram in cost-effectiveness analysis
    Hashem B El-Serag
    Health Services Research Sections, Houston Center for Quality of Care and Utilization Studies, Department of Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX, USA
    Arch Intern Med 162:2105-10. 2002
    ..Our objective in this study was to compare the cost-effectiveness of several strategies aimed at reducing the risk of clinical UGI events in NSAID users...
  46. pmc Obesity increases oesophageal acid exposure
    Hashem B El-Serag
    Section of Health Services Research, Houston Veterans Affairs Medical Center, Baylor College of Medicine, Houston, Texas 77030, USA
    Gut 56:749-55. 2007
    ..Obesity has been associated with gastro-oesophageal reflux disease (GERD); however, the mechanism by which obesity may cause GERD is unclear...
  47. ncbi request reprint The use of screening colonoscopy for patients cared for by the Department of Veterans Affairs
    Hashem B El-Serag
    Houston Center for Quality of Care and Utilization Studies, Michael E DeBakey VA Medical Center, Baylor College of Medicine, Houston, TX 77030, USA
    Arch Intern Med 166:2202-8. 2006
    ..Because of differences in the delivery of health care, this trend in use of colonoscopy in fee-for-service settings might not be paralleled in the Department of Veterans Affairs (VA)...
  48. pmc Barrett's esophagus in children and adolescents without neurodevelopmental or tracheoesophageal abnormalities: a prospective study
    Dang M Nguyen
    Baylor College of Medicine, Texas Children s Hospital, Houston, Texas 77030, USA
    Gastrointest Endosc 73:875-80. 2011
    ..Barrett's esophagus (BE) in children has been examined in retrospective studies, consisting of case series and cross-sectional studies...
  49. ncbi request reprint Physical and psychosocial contributors to quality of life in veterans with hepatitis C not on antiviral therapy
    Paul J Rowan
    Michael E DeBakey Veterans Affairs Medical Center, Houston, TX 77030, USA
    J Clin Gastroenterol 39:731-6. 2005
    ..Treatment-naive hepatitis C virus (HCV)-infected patients report impaired health-related quality of life (HRQOL), although causes are unclear. Psychosocial factors may be major determinants of HRQOL...
  50. ncbi request reprint Obesity is an independent risk factor for GERD symptoms and erosive esophagitis
    Hashem B El-Serag
    Section of Gastroenterology at the Houston Department of Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Gastroenterol 100:1243-50. 2005
    ..An association between obesity and GERD symptoms has been reported; however, study results have been inconsistent and it is not known whether an association persists after adjusting for other known GERD risk factors...
  51. doi request reprint Complications of pediatric colonoscopy: a five-year multicenter experience
    Kalpesh Thakkar
    Section of Pediatric Gastroenterology, Hepatology and Nutrition, Texas Children s Hospital and Baylor College of Medicine, Houston, Texas, USA
    Clin Gastroenterol Hepatol 6:515-20. 2008
  52. ncbi request reprint Management of the single liver nodule in a cirrhotic patient: a decision analysis model
    Hashem B El-Serag
    Sections of Gastroenterology, Houston Veterans Affairs Medical Center, Baylor College of Medicine, Houston, TX 77030, USA
    J Clin Gastroenterol 39:152-9. 2005
    ..The long waiting time prior to OLT limits its advantage over surgical resection in the treatment of patients with early HCC...
  53. pmc Dietary intake of vegetables, folate, and antioxidants and the risk of Barrett's esophagus
    Li Jiao
    Houston VA Health Services Research and Development Center of Excellence, Michael E DeBakey Veterans Affairs Medical Center, Houston, TX, USA
    Cancer Causes Control 24:1005-14. 2013
    ..Diet is a potentially modifiable risk factor for Barrett's esophagus (BE). We investigated the associations between intakes of fruits and vegetables and risk of BE...
  54. ncbi request reprint The use of cytokeratin stain to distinguish Barrett's esophagus from contiguous tissues: a systematic review
    Zhannat Nurgalieva
    Sections of Gastroenterology and Health Services Research, Houston Veterans Affairs Medical Center, and Department of Medicine, Baylor College of Medicine, Houston, Texas, USA
    Dig Dis Sci 52:1345-54. 2007
    ..CK immunostaining distinguished well between BE and IM in noncardiac segments of the stomach; however, these comparisons are not clinically relevant...
  55. ncbi request reprint Complications of pediatric EGD: a 4-year experience in PEDS-CORI
    Kalpesh Thakkar
    Section of Pediatric Gastroenterology, Department of Hepatology and Nutrition, Texas Children s Hospital and Baylor College of Medicine, Houston, Texas 77030, USA
    Gastrointest Endosc 65:213-21. 2007
    ..Available estimates of the incidence and type of complications during pediatric EGD are inconsistent...
  56. pmc Dietary fructose intake and severity of liver disease in hepatitis C virus-infected patients
    Gia L Tyson
    Houston VA Health Services Research and Development Center of Excellence, Michael E DeBakey Veterans Affairs Medical Center, Houston, TX, USA
    J Clin Gastroenterol 47:545-52. 2013
    ..This study aimed to determine whether dietary fructose intake is associated with advanced hepatic fibrosis and inflammation in an hepatitis C virus (HCV)-infected male population...
  57. pmc The impact of HIV viral control on the incidence of HIV-associated anal cancer
    Elizabeth Y Chiao
    Department of Medicine, Baylor College of Medicine, Houston, TX Houston Health Services Research and Development Center of Excellence, Michael E DeBakey Veterans Affairs Medical Center, Houston, TX and Baylor College of Medicine, Department of Medicine, Houston, TX
    J Acquir Immune Defic Syndr 63:631-8. 2013
    ..The effect of undetectable HIV viral loads as a result of successful cART has not been evaluated...
  58. pmc Automated identification of surveillance colonoscopy in inflammatory bowel disease using natural language processing
    Jason K Hou
    Houston VA HSR and D Center of Excellence, Michael E DeBakey Veterans Affairs Medical Center, Houston, TX, USA
    Dig Dis Sci 58:936-41. 2013
    ..The automated retrieval console (ARC) is natural language processing (NLP)-based software that allows text-based document-level classification...
  59. doi request reprint Process of care for hepatitis C infection is linked to treatment outcome and virologic response
    Fasiha Kanwal
    Houston VA Health Services Research and Development Center of Excellence, Health Services Research and Development Service, Michael E DeBakey Veterans Affairs Medical Center, Houston, Texas 77030, USA
    Clin Gastroenterol Hepatol 10:1270-1277.e3. 2012
    ..Process of care-based measures are used commonly to assess the quality of medical care provided to patients with chronic hepatitis C virus (HCV) infection. However, the links between these processes and patient outcomes are not clear...
  60. doi request reprint Practice patterns of surveillance endoscopy in a Veterans Affairs database of 29,504 patients with Barrett's esophagus
    Hashem B El-Serag
    the Michael E DeBakey Veterans Affairs Medical Center, 2002 Holcombe Blvd 152, Houston, TX 77030, USA
    Gastrointest Endosc 76:743-55. 2012
    ..Although surveys report that >95% of gastroenterologists recommend or practice BE surveillance, the extent and patterns of surveillance in clinical practice are unknown...
  61. pmc Epidemiology of viral hepatitis and hepatocellular carcinoma
    Hashem B El-Serag
    Section of Gastroenterology and Hepatology, Department of Medicine, Michael E DeBakey Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas, USA
    Gastroenterology 142:1264-1273.e1. 2012
    ....
  62. pmc Risk of colorectal cancer among Caucasian and African American veterans with ulcerative colitis
    Jason K Hou
    Houston VA HSR and D Center of Excellence, Michael E DeBakey Veterans Affairs Medical Center, Houston, Texas, USA
    Inflamm Bowel Dis 18:1011-7. 2012
    ..Ulcerative colitis (UC) is a risk factor for developing CRC; however, risk differences for CRC between African Americans and Caucasians with UC are unknown...
  63. pmc Gene expression in Barrett's esophagus: laser capture versus whole tissue
    Hashem B El-Serag
    Michael E DeBakey Veterans Administration Medical Center and Baylor College of Medicine, Houston, Texas, USA
    Scand J Gastroenterol 44:787-95. 2009
    ..The purpose of this study was to determine the degree of overlap of the two sample types and to define a set of genes that might serve as biochemical markers for BE...
  64. doi request reprint Prevalence of endoscopic findings of erosive esophagitis in children: a population-based study
    Mark A Gilger
    Department of Pediatrics, Baylor College of Medicine, Houston Center for Quality of Care and Utilization Studies, Veterans Administration Hospital, Houston, TX, USA
    J Pediatr Gastroenterol Nutr 47:141-6. 2008
    ..The prevalence of such GERD complications in children is unknown. The purpose of this study was to determine the prevalence of endoscopic findings of erosive esophagitis in children...
  65. ncbi request reprint Genetic variants of glutathione S-transferase as possible risk factors for hepatocellular carcinoma: a HuGE systematic review and meta-analysis
    Donna L White
    The Section of Gastroenterology, Michael E DeBakey Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX 77030, USA
    Am J Epidemiol 167:377-89. 2008
    ..However, given the relatively limited total number of subjects examined and observed between-study heterogeneity, chance could not be excluded...
  66. pmc Medications (NSAIDs, statins, proton pump inhibitors) and the risk of esophageal adenocarcinoma in patients with Barrett's esophagus
    Dang M Nguyen
    Section of Gastroenterology and Section of Health Services Research, Houston Department of Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas, USA
    Gastroenterology 138:2260-6. 2010
    ..However, the possible effect these medications may have on the risk of esophageal adenocarcinoma (EAC) in patients with existing Barrett's esophagus (BE) is unclear...
  67. ncbi request reprint Risk factors of intrahepatic cholangiocarcinoma in the United States: a case-control study
    Yasser H Shaib
    Section of Health Services Research, Michael E DeBakey Veterans Affairs Medical Center, Baylor College of Medicine, Houston, Texas 77030, USA
    Gastroenterology 128:620-6. 2005
    ..In this case-control study, we used the Surveillance, Epidemiology, and End Results-Medicare database to evaluate the prevalence of known risk factors for intrahepatic cholangiocarcinoma and explore other potential risk factors...
  68. ncbi request reprint The epidemiology of malignant gastrointestinal stromal tumors: an analysis of 1,458 cases from 1992 to 2000
    Thomas Tran
    Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Gastroenterol 100:162-8. 2005
    ..We conducted the first population-based study to evaluate the incidence and survival of malignant gastrointestinal stromal tumor in the United States...
  69. ncbi request reprint Hepatitis C infection and the increasing incidence of hepatocellular carcinoma: a population-based study
    Jessica A Davila
    Section of Health Services Research, Houston Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX 77030, USA
    Gastroenterology 127:1372-80. 2004
    ..A significant increase in the incidence of hepatocellular carcinoma (HCC) has been reported in the United States. The risk factors underlying this increase remain unclear...
  70. ncbi request reprint Diabetes increases the risk of acute hepatic failure
    Hashem B El-Serag
    Section of Gastroenterology, Houston Department of Veterans Affairs Medical Center, Texas 77030, USA
    Gastroenterology 122:1822-8. 2002
    ..It is unclear whether patients with diabetes are at an increased risk of developing acute liver failure (ALF). We performed a large cohort study to examine the occurrence of ALF by using the databases of the Department of Veterans Affairs...
  71. ncbi request reprint Is fibrolamellar carcinoma different from hepatocellular carcinoma? A US population-based study
    Hashem B El-Serag
    Section of Health Services Research, The Houston Veterans Affairs Medical Center and Baylor College of Medicine, 2002 Holcombe Boulevard 152, Houston, TX 77030, USA
    Hepatology 39:798-803. 2004
    ..In conclusion, in a population-based study, we observed remarkable differences in the epidemiology and prognosis of FLC compared to HCC...
  72. pmc Higher serum testosterone is associated with increased risk of advanced hepatitis C-related liver disease in males
    Donna L White
    Clinical Epidemiology and Outcomes Program, Houston VA Health Services Research and Development Center of Excellence, Michael E DeBakey Veterans Affairs Medical Center, Houston, TX 77030, USA
    Hepatology 55:759-68. 2012
    ..74; 95% CI: 1.86-6.54 versus OR(adjusted advanced inflammatory activity) = 2.23; 95% CI: 1.07-4.93, respectively)...
  73. pmc Level of α-fetoprotein predicts mortality among patients with hepatitis C-related hepatocellular carcinoma
    Gia L Tyson
    Houston VA Health Services Research and Development Center of Excellence, Michael E DeBakey Veterans Affairs Medical Center, Houston, Texas, USA
    Clin Gastroenterol Hepatol 9:989-94. 2011
    ..We investigated whether higher levels of AFP at the time of diagnosis are associated with increased mortality of patients with HCV-related HCC...
  74. pmc Medication usage and the risk of neoplasia in patients with Barrett's esophagus
    Dang M Nguyen
    Houston Center for Quality of Care and Utilization Studies, Michael E DeBakey Veterans Affairs Medical Center, Houston, Texas, USA
    Clin Gastroenterol Hepatol 7:1299-304. 2009
    ..However, only limited data are available on chemoprevention in patients with BE...
  75. doi request reprint Effectiveness of AFP and ultrasound tests on hepatocellular carcinoma mortality in HCV-infected patients in the USA
    Hashem B El-Serag
    The Michael E DeBakey VA Medical Center, Houston, TX 77030, USA
    Gut 60:992-7. 2011
    ..The objective of this study was to evaluate the effectiveness of HCC surveillance in a national Veterans Administration (VA) practice setting, using the national VA hepatitis C virus (HCV) Clinical Case Registry...
  76. doi request reprint The extent and determinants of prescribing and adherence with acid-reducing medications: a national claims database study
    Hashem B El-Serag
    Section of Gastroenterology and Hepatology, Houston Center for Quality of Care and Utilization Studies, The Michael E DeBakey Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Gastroenterol 104:2161-7. 2009
    ..No community-based, large-scale studies have examined the extent of prescribing acid-reducing medications or adherence and persistence to these medication regimens...
  77. ncbi request reprint Anthropometric correlates of intragastric pressure
    Hashem B El-Serag
    Sections of Health Services Research and Gastroenterology, Houston Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
    Scand J Gastroenterol 41:887-91. 2006
    ..However, the association between anthropometric measures of total body as well as abdominal obesity and intragastric pressure has not been examined...
  78. ncbi request reprint Utilization of screening for hepatocellular carcinoma in the United States
    Jessica A Davila
    Section of Health Services Research, Houston Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX, USA
    J Clin Gastroenterol 41:777-82. 2007
    ..Screening for hepatocellular carcinoma (HCC) has been recommended for patients at high-risk of developing HCC. Yet, the utilization and determinants of screening remain unclear...
  79. ncbi request reprint Hepatocellular carcinoma: recent trends in the United States
    Hashem B El-Serag
    The Houston Veterans Affairs Medical Center 152, 2002 Holcombe Boulevard, Houston, Texas 77030, USA
    Gastroenterology 127:S27-34. 2004
    ..The insulin resistance syndrome, manifesting as obesity and diabetes, is emerging as a risk factor for HCC in the United States; however, its impact on the current trend in HCC remains unclear...
  80. ncbi request reprint Psychiatric disorders among veterans with hepatitis C infection
    Hashem B El-Serag
    Section of Gastroenterology, The Houston Center for Quality Care and Utilization Studies, The Houston Veterans Affairs Medical Center and the Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
    Gastroenterology 123:476-82. 2002
    ..The presence of psychiatric, drug-, and alcohol-use disorders in hepatitis C virus (HCV)-infected patients may influence their management and prognosis. The frequency and the risk for these disorders among HCV-infected patients are unknown...
  81. ncbi request reprint The risk of end stage liver disease and hepatocellular carcinoma among persons infected with hepatitis C virus: publication bias?
    Boone Goodgame
    Section of Gastroenterology, Houston Veterans Affairs Medical Center, Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Gastroenterol 98:2535-42. 2003
    ..We performed a systematic review of the literature to identify and to analyze studies that examine such cohorts...
  82. ncbi request reprint Is there a true "shift" to the right colon in the incidence of colorectal cancer?
    Linda Rabeneck
    Department of Veterans Affairs Health Services Research, the Gastroenterology and Health Services Research Sections, Houston, Texas, USA
    Am J Gastroenterol 98:1400-9. 2003
    ..Previous studies have reported a migration in the occurrence of colorectal cancer (CRC) toward a proximal colonic location. To assess the potential impact of this, we evaluated recent temporal trends in the United States...
  83. pmc Reducing referral delays in colorectal cancer diagnosis: is it about how you ask?
    Hardeep Singh
    VA Medical Center 152, 2002 Holcombe Blvd, Houston, TX 77030, USA
    Qual Saf Health Care 19:e27. 2010
    ..The authors tested whether certain details of information transmitted through computerised provider order entry (CPOE)-based referrals affected timeliness of diagnostic colonoscopy for patients with newly diagnosed CRC...
  84. ncbi request reprint Abdominal obesity and the risk of Barrett's esophagus
    Hashem B El-Serag
    The Section of Gastroenterology, Houston Department of Veterans Affairs Medical Center, Houston, Texas 77030, USA
    Am J Gastroenterol 100:2151-6. 2005
    ..The association between overweight/obesity and the risk of Barrett's esophagus (BE) is unclear. Further, the association between body fat distribution and the risk of BE is unknown...
  85. pmc Hepatitis C infection and risk of diabetes: a systematic review and meta-analysis
    Donna L White
    Section of Gastroenterology and Hepatology, Baylor College of Medicine, Michael E DeBakey VA Medical Center, Houston, TX 77030, USA
    J Hepatol 49:831-44. 2008
    ..We performed meta-analyses to examine whether HCV infection does increase DM risk in comparison to the general population and in other sub-groups with increased liver disease rates including with hepatitis B (HBV)...
  86. ncbi request reprint Extrahepatic manifestations of hepatitis C among United States male veterans
    Hashem B El-Serag
    Section of Gastroenterology and Section of Health Services Research at The Houston Veterans Affairs Medical Center, Houston, TX, USA
    Hepatology 36:1439-45. 2002
    ..In conclusion, we found a significant association between HCV infection and PCT, lichen planus, vitiligo, cryoglobulinemia, membranoproliferative GN, and NHL. Patients presenting with these disorders should be tested for HCV infection...
  87. doi request reprint Oral bisphosphonate prescriptions and the risk of esophageal adenocarcinoma in patients with Barrett's esophagus
    Dang M Nguyen
    Gastroenterology, Baylor College of Medicine, Houston, TX, USA
    Dig Dis Sci 55:3404-7. 2010
    ..We therefore examined the association between these medications and the risk of esophageal adenocarcinoma (EAC) in patients with Barrett's esophagus (BE)...
  88. ncbi request reprint Adapting the Rx-Risk-V for mortality prediction in outpatient populations
    Michael L Johnson
    Houston Center for Quality of Care and Utilization Studies, Michael E DeBakey Veterans Affairs Medical Center, Houston, TX 77030, USA
    Med Care 44:793-7. 2006
    ..We sought to operationalize, test, and validate an outpatient pharmacy-based case-mix adjuster...
  89. pmc Statin therapy and serum transaminases among a cohort of HCV-infected veterans
    Louise M Henderson
    Department of Medicine, Baylor College of Medicine, Houston, TX, USA
    Dig Dis Sci 55:190-5. 2010
    ..We sought to determine the effect of statin therapy on serum AST and ALT levels in a cohort of HCV-infected veterans with well-characterized liver disease...
  90. doi request reprint Prevalence and histological features of the gastric cardia-type mucosa in children
    Hashem B El-Serag
    Section of Gastroenterology, Houston Center for Quality of Care and Utilization Studies, The Michael E DeBakey Veterans Affairs Medical Center 152, 2002 Holcombe Blvd, Houston, TX 77030, USA
    Dig Dis Sci 53:1792-6. 2008
    ..We examined the presence and determinants of gastric cardia-type mucosa at a normally located z-line in children without underlying gastroesophageal reflux disease (GERD)-predisposing disorders...
  91. ncbi request reprint Hepatocellular carcinoma and hepatitis C in the United States
    Hashem B El-Serag
    Sections of Gastroenterology and Health Services Research at the Houston Department of Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX, 77030, USA
    Hepatology 36:S74-83. 2002
    ..Future research should focus on improving understanding of the incidence and risk factors for HCC, causes of HCV-related carcinogenesis, means of early detection, and better treatment for HCC...
  92. ncbi request reprint Oral contraception and the risk of hepatocellular carcinoma
    Shail Maheshwari
    Sections of Gastroenterology and Health Services Research at the Michael E DeBakey Veterans Affairs Medical Center and Baylor College of Medicine, 2002 Holcombe Blvd, Houston, TX 77030, USA
    J Hepatol 47:506-13. 2007
    ..We performed a meta-analysis of observational epidemiological studies to examine the association between oral contraceptives (OC) and hepatocellular carcinoma (HCC)...
  93. doi request reprint Diagnosis and treatment of hepatocellular carcinoma
    Hashem B El-Serag
    Section of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, Texas 77030, USA
    Gastroenterology 134:1752-63. 2008
    ..In this article, we present a summary of the most recent information on screening, diagnosis, staging, and different treatment modalities of HCC, as well as our recommended management approach...
  94. ncbi request reprint The association between diabetes and hepatocellular carcinoma: a systematic review of epidemiologic evidence
    Hashem B El-Serag
    Section of Gastroenterology, Michael E DeBakey Veterans Affairs Medical Center at Baylor College of Medicine, Houston, Texas 77030, USA
    Clin Gastroenterol Hepatol 4:369-80. 2006
    ..We conducted a systematic review and a meta-analysis to estimate the magnitude and determinants of association between diabetes and hepatocellular carcinoma (HCC)...
  95. ncbi request reprint Epidemiology of hepatocellular carcinoma in Hispanics in the United States
    Hashem B El-Serag
    Section of Gastroenterology, The Houston Veterans Affairs Medical Center, 2002 Holcombe Boulevard, Houston, TX 77030, USA
    Arch Intern Med 167:1983-9. 2007
    ..In previous studies, the rates for Hispanics have not been reported separately from other racial or ethnic groups...
  96. doi request reprint Human immunodeficiency virus-associated squamous cell cancer of the anus: epidemiology and outcomes in the highly active antiretroviral therapy era
    Elizabeth Y Chiao
    Department of Medicine, Baylor College of Medicine, Houston Center for Quality of Care and Utilization Studies, Michael E DeBakey Veterans Affairs Medical Center 152, 2002 Holcombe Blvd, Houston, TX 77030, USA
    J Clin Oncol 26:474-9. 2008
    ....
  97. doi request reprint Epidemiology of non-erosive reflux disease
    Hashem B El-Serag
    Department of Medicine, Baylor College of Medicine and The Houston Center for Quality of Care and Utilization Studies, Health Services Research and Development Service, Department of Veterans Affairs Medical Center, Houston, Tex 77030, USA
    Digestion 78:6-10. 2008
    ..The temporal trends in NERD are unclear, and are probably increasing because GERD symptom prevalence has increased...
  98. ncbi request reprint Time trends of gastroesophageal reflux disease: a systematic review
    Hashem B El-Serag
    Gastroenterology and Health Services Research Sections, Michael E DeBakey VA Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
    Clin Gastroenterol Hepatol 5:17-26. 2007
    ..If this trend continues, it could contribute to the rapidly increasing incidence of more serious complications associated with GERD, such as esophageal adenocarcinoma, as well as costs to healthcare systems and employers...
  99. doi request reprint The risk of hepatocellular carcinoma in patients with previous malignancy
    Abby B Siegel
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10033, USA
    Cancer Invest 26:511-5. 2008
  100. ncbi request reprint Screening for hepatocellular carcinoma among veterans with hepatitis C on disease stage, treatment received, and survival
    Luci K Leykum
    South Texas Veterans Health Care System, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA
    Clin Gastroenterol Hepatol 5:508-12. 2007
    ..The purpose of this study was to examine the determinants of screening, as well as the impact of screening on disease stage, treatment received, and survival in a US veteran population...
  101. ncbi request reprint Geographic variation within the United States in the incidence of hepatocellular carcinoma
    Jessica A Davila
    Health Services Research, The Houston Veterans Affairs Medical Center, 2002 Holcombe Blvd 152, Houston, TX 77030, USA
    J Clin Epidemiol 56:487-93. 2003
    ..Significant geographic variation in HCC incidence exist in the United States. These variations are only partly explained by differences in age, gender, race, and year of diagnosis...