El Sayed H El-Ashry

Summary

Publications

  1. ncbi request reprint Components, therapeutic value and uses of myrrh
    E S H El Ashry
    Chemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt
    Pharmazie 58:163-8. 2003
  2. doi request reprint Regioselective synthesis, characterization and antimicrobial evaluation of S-glycosides and S,N-diglycosides of 1,2-Dihydro-5-(1H-indol-2-yl)-1,2,4-triazole-3-thione
    El Sayed H El Ashry
    HEJ Research Institute for Chemistry, International Center for Chemical and Biological Sciences, Karachi University, Karachi, Pakistan
    Eur J Med Chem 66:106-13. 2013
  3. doi request reprint Immunomodulatory properties of S- and N-alkylated 5-(1H-indol-2-yl)-1,3,4-oxadiazole-2(3H)-thione
    El Sayed H El Ashry
    International Center for Chemical and Biological Sciences, H E J Research Institute of Chemistry, Karachi University, Karachi, Pakistan
    J Enzyme Inhib Med Chem 28:105-12. 2013
  4. doi request reprint The use of propolis as vaccine's adjuvant
    El Sayed H El Ashry
    Chemistry Department, Alexandria University, Alexandria, Egypt
    Vaccine 31:31-9. 2012
  5. doi request reprint Synthesis, biological evaluation, and molecular docking studies of benzyl, alkyl and glycosyl [2-(arylamino)-4,4-dimethyl-6-oxo-cyclohex-1-ene]carbodithioates, as potential immunomodulatory and immunosuppressive agents
    El Sayed H El Ashry
    HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan
    Bioorg Med Chem 20:3000-8. 2012
  6. doi request reprint Quantitative structure activity relationships of some pyridine derivatives as corrosion inhibitors of steel in acidic medium
    El Sayed H El Ashry
    Department of Chemistry, Faculty of Science, Alexandria University, Alexandria, Egypt
    J Mol Model 18:1173-88. 2012
  7. ncbi request reprint Synthesis of AZT analogues: 7-(3-azido-2-hydroxypropyl)-, 7-(3-amino-2-hydroxypropyl)-,7-(3-triazolyl-2-hydroxypropyl)theophylline
    El Sayed H El Ashry
    Department of Chemistry, Faculty of Science, Alexandria University, Alexandria, Egypt
    Nucleosides Nucleotides Nucleic Acids 25:299-305. 2006
  8. doi request reprint Synthesis and X-ray analysis of butyl and glycosyl (2-arylamino-4,4-dimethyl-6-oxocyclohex-1-ene)carbodithioates and their possible cyclization to 2-thioxo-6,7-dihydro-1H-benzo[d][1,3]thiazin-5(2H)-one derivatives
    El Sayed H El Ashry
    H E J Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan
    Carbohydr Res 346:169-76. 2011
  9. doi request reprint Revisit to the reaction of o-phenylene diamine with thiosemicarbazide to give benzimidazole-2-thione rather than benzotriazine-2-thione and its glycosylation
    El Sayed H El Ashry
    International Center for Chemical and Biological Science, H E J Research Institute of Chemistry, University of Karachi, Karachi, Pakistan
    Nucleosides Nucleotides Nucleic Acids 29:698-706. 2010
  10. doi request reprint Regioselectivity in the glycosylation of 5-(3-chlorobenzo[b]thien-2-yl)-4H-1,2,4-triazole-3-thiol
    El Sayed H El Ashry
    Chemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt
    Carbohydr Res 344:725-33. 2009

Collaborators

  • Mohamed R Aouad
  • M Ahmed Mesaik
  • Mohamed R E Aly
  • Zaheer ul-Haq
  • E S H El Ashry
  • Mohammed T Abdel-Aal
  • A Ismail
  • El Sayed H El Ashry
  • E S H El Ashry
  • A Saleh
  • Aly A Aly
  • Ahmed T A Boraei
  • Mohy El Din Abd El Fattah
  • El Sayed H El Tamany
  • Nehad M Abdel-Monem
  • Almas Jabeen
  • Samreen Soomro
  • Omer M Abdalla
  • A Chamseddine
  • Mohammed R Amer
  • Mahmoud Balbaa
  • Asmaa Nabil-Adam
  • Heba M Abd El-Nabi
  • Beenish Fatima
  • Ahmed Shukrulla
  • Ahmed M Abdel-Azeem
  • Doaa A Ghareeb
  • Sobia Ahsan Halim
  • M Ahmed Mesaik
  • Safaa Ragab
  • Ahmed El Nemr
  • Mohammad R Amer
  • Seik W Ng
  • Muhammad R Shah
  • F Khodari
  • B Obeid
  • H Zein
  • Sherine A N Khattab
  • Farida Louis
  • Hamida M Abdel-Hamid
  • Ahmed A Kassem
  • L Kamel
  • A Ghali
  • H El Khayat
  • A I Atta
  • Laila F Awad
  • Hanaa A Rasheed
  • Nagwa Rashed
  • Adel Abdel-Rahman
  • L F Awad
  • H M Abdel Hamid
  • M M Abdul-Ghani
  • O M Salama
  • N Rashed
  • Hany El-Sawy
  • Hamdi Mansour

Detail Information

Publications21

  1. ncbi request reprint Components, therapeutic value and uses of myrrh
    E S H El Ashry
    Chemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt
    Pharmazie 58:163-8. 2003
    ..The constituents of the volatile oil, the resin and the gum are outlined in detail. Myrrh has considerable antimicrobial activity and is medicinally used in a variety of diseases...
  2. doi request reprint Regioselective synthesis, characterization and antimicrobial evaluation of S-glycosides and S,N-diglycosides of 1,2-Dihydro-5-(1H-indol-2-yl)-1,2,4-triazole-3-thione
    El Sayed H El Ashry
    HEJ Research Institute for Chemistry, International Center for Chemical and Biological Sciences, Karachi University, Karachi, Pakistan
    Eur J Med Chem 66:106-13. 2013
    ..The compounds were screened for their antibacterial and antifungal activities. Some compounds exhibited strong inhibition activity compared with the reference drugs (chloramphenicol and baneocin)...
  3. doi request reprint Immunomodulatory properties of S- and N-alkylated 5-(1H-indol-2-yl)-1,3,4-oxadiazole-2(3H)-thione
    El Sayed H El Ashry
    International Center for Chemical and Biological Sciences, H E J Research Institute of Chemistry, Karachi University, Karachi, Pakistan
    J Enzyme Inhib Med Chem 28:105-12. 2013
    ..Cytotoxic effect on T-cell proliferation was tested on NIH-3T3 mouse fibroblast normal cell line. All compounds were found to be free from toxic effects up to 100 μM concentration...
  4. doi request reprint The use of propolis as vaccine's adjuvant
    El Sayed H El Ashry
    Chemistry Department, Alexandria University, Alexandria, Egypt
    Vaccine 31:31-9. 2012
    ..This comprehensive up-to-date review categorizes, documents, and discusses those trials in a clear chronological manner...
  5. doi request reprint Synthesis, biological evaluation, and molecular docking studies of benzyl, alkyl and glycosyl [2-(arylamino)-4,4-dimethyl-6-oxo-cyclohex-1-ene]carbodithioates, as potential immunomodulatory and immunosuppressive agents
    El Sayed H El Ashry
    HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan
    Bioorg Med Chem 20:3000-8. 2012
    ....
  6. doi request reprint Quantitative structure activity relationships of some pyridine derivatives as corrosion inhibitors of steel in acidic medium
    El Sayed H El Ashry
    Department of Chemistry, Faculty of Science, Alexandria University, Alexandria, Egypt
    J Mol Model 18:1173-88. 2012
    ..It was found that theoretical data support the experimental results. The results were used to predict the corrosion inhibition of 24 related pyridine derivatives...
  7. ncbi request reprint Synthesis of AZT analogues: 7-(3-azido-2-hydroxypropyl)-, 7-(3-amino-2-hydroxypropyl)-,7-(3-triazolyl-2-hydroxypropyl)theophylline
    El Sayed H El Ashry
    Department of Chemistry, Faculty of Science, Alexandria University, Alexandria, Egypt
    Nucleosides Nucleotides Nucleic Acids 25:299-305. 2006
    ..Selective acetylation of 4 gave the N-acetyl derivative 5. 1,3-Dipolar cycloaddition of the azide group in 2 with N1-propargyl thymine (6) afforded the regioisomeric triazole 7...
  8. doi request reprint Synthesis and X-ray analysis of butyl and glycosyl (2-arylamino-4,4-dimethyl-6-oxocyclohex-1-ene)carbodithioates and their possible cyclization to 2-thioxo-6,7-dihydro-1H-benzo[d][1,3]thiazin-5(2H)-one derivatives
    El Sayed H El Ashry
    H E J Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan
    Carbohydr Res 346:169-76. 2011
    ..The amount of carbon disulfide plays a great role in the mode of reaction. The structures of the synthesized compounds were elucidated by spectral data and X-ray crystallography...
  9. doi request reprint Revisit to the reaction of o-phenylene diamine with thiosemicarbazide to give benzimidazole-2-thione rather than benzotriazine-2-thione and its glycosylation
    El Sayed H El Ashry
    International Center for Chemical and Biological Science, H E J Research Institute of Chemistry, University of Karachi, Karachi, Pakistan
    Nucleosides Nucleotides Nucleic Acids 29:698-706. 2010
    ..The regioselectivity of glycosylation reaction has been investigated...
  10. doi request reprint Regioselectivity in the glycosylation of 5-(3-chlorobenzo[b]thien-2-yl)-4H-1,2,4-triazole-3-thiol
    El Sayed H El Ashry
    Chemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt
    Carbohydr Res 344:725-33. 2009
    ..Microwave irradiation (MWI) led to higher yields in much less time than the conventional methods, and no change in regioselectivity has been noticed...
  11. ncbi request reprint Synthesis of mono- and di-hydroxylated prolines and 2-hydroxymethylpyrrolidines from non-carbohydrate precursors
    El Sayed H El-Ashry
    Chemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt
    Carbohydr Res 338:2265-90. 2003
    ....
  12. ncbi request reprint Reaction of sugars with 2-hydrazinopyridine, precursors for seco C-nucleosides of 1,2,4-triazolo[4,3-a]pyridine
    E S H El Ashry
    Chemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt
    Nucleosides Nucleotides Nucleic Acids 23:567-80. 2004
    ..Assignment of 1D and 2D NMR spectral data in addition to 15N NMR experiments led to complete characterization of the products...
  13. ncbi request reprint Synthesis of 2-bromomethyl-3-hydroxy-2-hydroxymethyl-propyl pyrimidine and theophylline nucleosides under microwave irradiation. Evaluation of their activity against hepatitis B virus
    E S H El Ashry
    Department of Chemistry, Faculty of Science, Alexandria University, Alexandria, Egypt
    Nucleosides Nucleotides Nucleic Acids 25:925-39. 2006
    ..The activity of deacetylated nucleosides against Hepatitis B virus was evaluated. Compound 5b showed moderate inhibition activity against HBV with mild cytotoxicity...
  14. ncbi request reprint Microwave-assisted organic synthesis of 3-(D-Gluco-pentitol-1-yl)-1H-1,2,4-triazole
    E S H El Ashry
    Chemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt
    Nucleosides Nucleotides Nucleic Acids 25:325-35. 2006
    ..The structures of the synthesized compounds were confirmed by 1H NMR, 2D NMR, and mass spectra...
  15. doi request reprint [Posterolateral rotatory instability of the elbow secondary to sprain]
    A Chamseddine
    Service de chirurgie orthopédique et de traumatologie, hôpital Sahel, Centre Hospitalier Universitaire, Ghoubeiry, Beirut, Lebanon
    Chir Main 30:52-5. 2011
    ....
  16. ncbi request reprint Serum levels of astroglial S100-beta and neuron-specific enolase in hepatic encephalopathy patients
    A Saleh
    Department of Clinical Chemistry, Theodor Bilharz Research Institute, Cairo, Egypt
    East Mediterr Health J 13:1114-23. 2007
    ..3% and sensitivity of 51.7% for detection of HE from cirrhosis. Serum S100beta may be a useful surrogate marker for the diagnosis of mild cognitive impairment in cirrhotic patients before they progress to more advanced stages of HE...
  17. ncbi request reprint Novel regioselective formation of S- and N-hydroxyl-alkyls of 5-(3-chlorobenzo[b]thien-2-yl)-3-mercapto-4H-1,2,4-triazole and a facile synthesis of triazolo-thiazoles and thiazolo-triazoles. Role of catalyst and microwave
    E S H El Ashry
    Chemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt
    Nucleosides Nucleotides Nucleic Acids 26:437-51. 2007
    ..The isopropylidenes and acetyl derivatives of the products were prepared...
  18. ncbi request reprint Novel regioselective hydroxyl-alkylation of 4,5-diphenylimidazole-2-thione and a competitive intramolecular ring closure of the S-hydroxyalkyl-imidazoles to imidazo[2,1-b]thiazines and thiazoles. Role of catalyst, microwave irradiation, and solid support
    E S H El Ashry
    Chemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt
    Nucleosides Nucleotides Nucleic Acids 26:423-35. 2007
    ..Isopropylidenation of 12 and 13 and deprotection of 9 and 10 also were investigated...
  19. ncbi request reprint Inhibition of some hepatic glycosidases by the diseco nucleoside, 4-amino-3-(D-glucopentitol-1-yl)-5-mercapto-1,2,4-triazole and its 3-methyl analog
    Mahmoud Balbaa
    Department of Biochemistry, Faculty of Science, Alexandria University, Alexandria, Egypt
    Nucleosides Nucleotides Nucleic Acids 21:695-708. 2002
    ..The compounds showed a reversible inhibition of a competitive type for alpha-glucosidase. Moreover, they exert a relatively potent inhibition on alpha-glucosidase with a Ki magnitude of 3.6 x 10(-4), 9.5 x 10(-5) M...
  20. pmc Pretreatment hepatoprotective effect of the marine fungus derived from sponge on hepatic toxicity induced by heavy metals in rats
    Nehad M Abdel-Monem
    Department of Biochemistry, Faculty of Science, Alexandria University, Alexandria, Egypt
    Biomed Res Int 2013:510879. 2013
    ..The results prove that TS extract possesses a hepatoprotective property due to its proven antioxidant and free-radical scavenging properties...
  21. doi request reprint Synthesis and antiviral evaluation of novel 5-(N-Aryl-aminomethyl-1,3,4-oxadiazol-2-yl)hydrazines and their sugars, 1,2,4-triazoles, tetrazoles and pyrazolyl derivatives
    Mohammed T Abdel-Aal
    Chemistry Department, Faculty of Science, Menofia University, Shebin El Koom, Egypt
    Arch Pharm (Weinheim) 341:307-13. 2008
    ..The results revealed that the sugar hydrazones 6a,b showed higher antiviral activity compared to the other hydrazones and their acetylated derivatives...