Maternal CD4+ cell count decline after interruption of antiretroviral prophylaxis for the prevention of mother-to-child transmission of HIVDidier Ekouevi
MTCT Plus Initiative Programme, PACCI, Abidjan, Cote d Ivoire
PLoS ONE 7:e43750. 2012
..We evaluated maternal CD4+ cell count (CD4+) decline after PMTCT prophylaxis in a multi-country HIV care program...
- Feasibility and acceptability of rapid HIV screening in a labour ward in Togo
Didier K Ekouevi
Département des Sciences Biologiques et Santé Publique, Faculté Mixte de Médecine et de Pharmacie, Lome, Togo
J Int AIDS Soc 15:17380. 2012
..Little is known about the feasibility and acceptability of HIV screening during labour in West Africa...
- Health facility characteristics and their relationship to coverage of PMTCT of HIV services across four African countries: the PEARL study
Didier K Ekouevi
Programme PAC CI, Abidjan, Cote d Ivoire, France
PLoS ONE 7:e29823. 2012
..CONCLUSIONS/RESULTS: We observed a positive relationship between an antenatal quality score and PMTCT coverage but did not identify a consistent set of variables that predicted PMTCT coverage...
- 12-month mortality and loss-to-program in antiretroviral-treated children: The IeDEA pediatric West African Database to evaluate AIDS (pWADA), 2000-2008
Didier K Ekouevi
INSERM, U897, and Institut de Santé Publique, Epidémiologie et Développement, Universite Victor Segalen Bordeaux 2, Bordeaux, France
BMC Public Health 11:519. 2011
..We describe here the characteristics at antiretroviral treatment (ART) initiation and study the 12-month mortality and loss-to-program of HIV-infected children followed in ART programs in West Africa...
- Pregnancy outcomes in women exposed to efavirenz and nevirapine: an appraisal of the IeDEA West Africa and ANRS Databases, Abidjan, Côte d'Ivoire
Didier K Ekouevi
Programme PAC CI, Abidjan, Cote d Ivoire
J Acquir Immune Defic Syndr 56:183-7. 2011
..An increasing number of HIV-infected women become pregnant while receiving efavirenz (EFV). We compared the pregnancy outcomes of women exposed to EFV and to nevirapine (NVP) during the first trimester...
- Coverage of intermittent prevention treatment with sulphadoxine-pyrimethamine among pregnant women and congenital malaria in Côte d'Ivoire
Henriette A Vanga-Bosson
Programme PAC CI, Abidjan, Cote d Ivoire
Malar J 10:105. 2011
..Data on IPT-SP coverage and factors associated with placental malaria parasitaemia and low birth weight (LBW) are scarce in Côte d'Ivoire...
Strengthening health systems through HIV monitoring and evaluation in Sub-Saharan AfricaDidier K Ekouevi
Programme PACCI, Abidjan, Cote d Ivoire
Curr Opin HIV AIDS 6:245-50. 2011
..In this review, we describe the challenges faced by using clinical cohorts to perform Monitoring and Evaluation (M&E) and the possible solutions for increasing and strengthening health systems in low-income and middle-income countries...
- Antiretroviral therapy in pregnant women with advanced HIV disease and pregnancy outcomes in Abidjan, Côte d'Ivoire
Didier K Ekouevi
ANRS 1201 1202 DITRAME PLUS Project, PACCI Collaboration, Abidjan, Cote d Ivoire, France
AIDS 22:1815-20. 2008
..Pregnancy outcomes in women receiving highly active antiretroviral treatment (HAART) in Africa are not well described...
- Two-year morbidity-mortality and alternatives to prolonged breast-feeding among children born to HIV-infected mothers in Côte d'Ivoire
Renaud Becquet
Institut National de la Santé et de la Recherche Médicale Unité 593, Universite Victor Segalen, Bordeaux, France
PLoS Med 4:e17. 2007
..Little is known about the long-term safety of infant feeding interventions aimed at reducing breast milk HIV transmission in Africa...
- Antiretroviral treatment and prevention of peripartum and postnatal HIV transmission in West Africa: evaluation of a two-tiered approach
Besigin Tonwe Gold
MTCT Plus Programme, ACONDA, Abidjan, Cote d Ivoire
PLoS Med 4:e257. 2007
....
- Maternal 12-month response to antiretroviral therapy following prevention of mother-to-child transmission of HIV type 1, Ivory Coast, 2003-2006
Patrick A Coffie
Unité Institut National de Santé et de Rechereche Médicale 593, Bordeaux, France
Clin Infect Dis 46:611-21. 2008
....
Variation of CD4 count and percentage during pregnancy and after delivery: implications for HAART initiation in resource-limited settingsDidier K Ekouevi
Programme PACCI, Abidjan, Cote d Ivoire, INSERM, Unité 593, Bordeaux, France
AIDS Res Hum Retroviruses 23:1469-74. 2007
..To accurately target the most appropriate time to start HAART, the CD4 percentage could be more reliable than the absolute count in sub-Saharan African pregnant women...
- CD4 percentages and total lymphocyte counts as early surrogate markers for pediatric HIV-1 infection in resource-limited settings
Francois Rouet
Centre de Diagnostic et de Recherches sur le SIDA CeDReS, Centre Hospitalier Universitaire de Treichville, Abidjan, Cote d Ivoire
J Trop Pediatr 52:346-54. 2006
..CD4% should be further evaluated under field conditions for the diagnosis of pediatric HIV-1 infection and the monitoring of pediatric antiretroviral therapy...
- 18-month effectiveness of short-course antiretroviral regimens combined with alternatives to breastfeeding to prevent HIV mother-to-child transmission
Valeriane Leroy
French National Institute for Health and Medical Research INSERM, Unité 897, Centre de Recherche Epidémiologie et Biostatistique, Bordeaux, France
PLoS ONE 3:e1645. 2008
..We assessed the 18-month effectiveness of short-course (sc) antiretroviral peripartum regimens combined with alternatives to prolonged breastfeeding to prevent mother-to-child transmission (MTCT) of HIV-1 in Abidjan, Côte d'Ivoire...
- Early mixed feeding and breastfeeding beyond 6 months increase the risk of postnatal HIV transmission: ANRS 1201/1202 Ditrame Plus, Abidjan, Côte d'Ivoire
Renaud Becquet
INSERM, Unité 897, Centre de Recherche Epidémiologie et Biostatistique, Bordeaux, France
Prev Med 47:27-33. 2008
..To evaluate the risk of postnatal HIV transmission among women in Abidjan, Côte d'Ivoire offered alternatives to prolonged breastfeeding, and to assess the impact of the breastfeeding pattern and duration on this risk...
- Complementary feeding adequacy in relation to nutritional status among early weaned breastfed children who are born to HIV-infected mothers: ANRS 1201/1202 Ditrame Plus, Abidjan, Cote d'Ivoire
Renaud Becquet
Unité INSERM 593, Institut de Santé Publique Epidémiologie et Développement, Universite Victor Segalen, Bordeaux, France
Pediatrics 117:e701-10. 2006
....
- Knowledge, attitudes, and beliefs of health care workers regarding alternatives to prolonged breast-feeding (ANRS 1201/1202, Ditrame Plus, Abidjan, Côte d'Ivoire)
Renaud Becquet
Unité INSERM 593, Institut de Santé Publique Epidémiologie Développement, Universite Victor Segalen, Bordeaux, France
J Acquir Immune Defic Syndr 40:102-5. 2005
..However, proposing alternatives to prolonged breast-feeding causes difficulties for health care workers that should be taken into account when tailoring such complex interventions...
- Universal antiretroviral therapy for pregnant and breast-feeding HIV-1-infected women: towards the elimination of mother-to-child transmission of HIV-1 in resource-limited settings
Renaud Becquet
INSERM, Unité 897, Centre de Recherche Epidémiologie et Biostatistique, Bordeaux, France
Clin Infect Dis 49:1936-45. 2009
..On the basis of available evidence, we suggest translating into practice the recently available evidence on this matter without any further delay...
- Acceptability of exclusive breast-feeding with early cessation to prevent HIV transmission through breast milk, ANRS 1201/1202 Ditrame Plus, Abidjan, Côte d'Ivoire
Renaud Becquet
Unité INSERM 593, Institut de Santé Publique Epidémiologie Développement ISPE, Universite Victor Segalen, Bordeaux, France
J Acquir Immune Defic Syndr 40:600-8. 2005
..We assessed the uptake of a nutritional intervention promoting exclusive breast-feeding with early cessation between 3 and 4 months of age to reduce postnatal transmission of HIV in Abidjan, Côte d'Ivoire...
- Incidence and risk factors of severe adverse events with nevirapine-based antiretroviral therapy in HIV-infected women. MTCT-Plus program, Abidjan, Côte d'Ivoire
Patrick A Coffie
Programme MTCT Plus, ACONDA, BP 1954 Abidjan 18, Abidjan, Cote d Ivoire
BMC Infect Dis 10:188. 2010
..We estimated the incidence of SAEs according to CD4 cell count and identify their risk factors in nevirapine-treated women...
- CD4-specific mortality rates among HIV-infected adults with high CD4 counts and no antiretroviral treatment in West Africa
Charlotte Lewden
INSERM, U897, Bordeaux, France
J Acquir Immune Defic Syndr 59:213-9. 2012
..CD4-specific rates of mortality in sub-Saharan African adults with high CD4 counts have rarely been estimated. This estimation is useful to the when to start antiretroviral treatment (ART) debate...
- Prevalence of resistance to nevirapine in mothers and children after single-dose exposure to prevent vertical transmission of HIV-1: a meta-analysis
Elise Arrive
Unité INSERM 593, Bordeaux, France
Int J Epidemiol 36:1009-21. 2007
..This systematic review and meta-analysis of summarized data aimed to estimate the proportion of mothers and children with NVP resistance mutations detected in plasma samples 4-8 weeks postpartum after single-dose NVP use for PMTCT...
- Immune status and uptake of antiretroviral interventions to prevent mother-to-child transmission of HIV-1 in Africa
Didier K Ekouevi
Projet ANRS 1201 1202 Ditrame Plus and CeDReS, Programme PACCI, Abidjan, Cote d Ivoire, France
J Acquir Immune Defic Syndr 36:755-7. 2004
..425/mm3; P=0.47). The overall uptake of the intervention (31.9%) appeared to be independent of the maternal immune status...
- Cervical cancer screening by visual inspection in Côte d'Ivoire, operational and clinical aspects according to HIV status
Apollinaire Horo
Service de Gynecologie Obstetrique, Centre Hospitalier Universitaire de Yopougon, Abidjan, Cote d Ivoire, France
BMC Public Health 12:237. 2012
..Cervical cancer screening is not yet standard of care of women attending HIV care clinics in Africa and presents operational challenges that need to be addressed...
- Transfer and evaluation of an automated, low-cost real-time reverse transcription-PCR test for diagnosis and monitoring of human immunodeficiency virus type 1 infection in a West African resource-limited setting
Francois Rouet
Centre de Diagnostic et de Recherches sur le SIDA, Abidjan, Cote d Ivoire
J Clin Microbiol 43:2709-17. 2005
..The TaqMan real-time PCR (12 dollars per test) is now routinely used to monitor HIV-1 infection in our laboratory. This technology should be further evaluated in limited-resource countries where strains other than CRF02 are prevalent...
- Nevirapine for the prevention of mother-to-child transmission of HIV: a nation-wide coverage survey in Côte d'Ivoire
Patrick A Coffie
Programme PACCI Pôle Mère enfant, Abidjan, Cote d Ivoire
J Acquir Immune Defic Syndr 57:S3-8. 2011
..We evaluated NVP coverage among HIV-infected delivering women in Côte d'Ivoire...
- Children who acquire HIV infection perinatally are at higher risk of early death than those acquiring infection through breastmilk: a meta-analysis
Renaud Becquet
Institut National de la Sante et de la Recherche Medicale, Unité 897, Centre de Recherche Epidémiologie et Biostatistique, Bordeaux, France
PLoS ONE 7:e28510. 2012
..We highlight the urgent need for the prevention of peri-partum and postnatal transmission and timely assessment of HIV infection in infants to initiate antiretroviral care and support for HIV-infected children...
- Infant feeding practices before implementing alternatives to prolonged breastfeeding to reduce HIV transmission through breastmilk in Abidjan, Cote d'Ivoire
Renaud Becquet
Unité INSERM 593, Institut de Santé Publique Epidémiologie Développement, Universite Victor Segalen, Bordeaux, France
J Trop Pediatr 51:351-5. 2005
..This study provides useful information for planning purposes in this urban African population, where exclusive breastfeeding is rare and the use of infant formula relatively common...
- Low retention of HIV-infected patients on antiretroviral therapy in 11 clinical centres in West Africa
Didier K Ekouevi
INSERM, U897, and ISPED, Universite Bordeaux 2, Bordeaux, France
Trop Med Int Health 15:34-42. 2010
..To study factors associated with the probability of retention in antiretroviral therapy (ART) programmes in West Africa...
- Pharmacovigilance for antiretroviral drugs in Africa: lessons from a study in Abidjan, Cote d'Ivoire
Antoine Jaquet
INSERM CRE U 897, Institute of Public Health and Development, Universite Victor Segalen, Bordeaux, France
Pharmacoepidemiol Drug Saf 20:1303-10. 2011
..We assessed knowledge towards pharmacovigilance among ART prescribers and available capacity of HIV clinics to conduct ADR monitoring in Abidjan, Côte d'Ivoire...
- Maternal and nenonatal tenofovir and emtricitabine to prevent vertical transmission of HIV-1: tolerance and resistance
Elise Arrive
INSERM U897, Universite Victor Segalen Bordeaux 2, 33076 Bordeaux Cedex, France
AIDS 24:2481-8. 2010
..We aimed to evaluate the tolerance and resistance profiles of a combination of tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC) given to HIV-1-infected delivering women and their newborns...
- Alcohol use and non-adherence to antiretroviral therapy in HIV-infected patients in West Africa
Antoine Jaquet
HIV Epidemiology, INSERM CRE U 897, Institut de Santé Publique, Epidémiologie et Développement, Universite Victor Segalen, Bordeaux 2, France
Addiction 105:1416-21. 2010
..To investigate the association between alcohol use and adherence to highly active antiretroviral treatment (HAART) among human immunodeficiency virus (HIV)-infected patients in sub-Saharan Africa...
- The spectrum of cancers in West Africa: associations with human immunodeficiency virus
Aristophane Tanon
Service de Maladies Infectieuses et Tropicales, CHU de Treichville, Abidjan, Cote d Ivoire
PLoS ONE 7:e48108. 2012
..Our objective was to estimate the association between HIV infection and selected types of cancers among patients hospitalized for diagnosis or treatment of cancer in West Africa...
- Acceptability and uptake of a package to prevent mother-to-child transmission using rapid HIV testing in Abidjan, Côte d'Ivoire
Didier K Ekouevi
Project ANRS Ditrame Plus, Programme PACCI, Abidjan,
AIDS 18:697-700. 2004
- The challenge of AIDS-related malignancies in sub-Saharan Africa
Annie J Sasco
INSERM, U 897, Epidemiology for Cancer Prevention, Bordeaux, France
PLoS ONE 5:e8621. 2010
..The objective of our paper is to review the link between HIV and cancer in sub-Saharan Africa, putting it in perspective with what is already known in Western countries...
