Linda Saxe Einbond

Summary

Publications

  1. ncbi request reprint Actein induces calcium release in human breast cancer cells
    Linda Saxe Einbond
    Columbia University College of Physicians and Surgeons, New York, NY 10032, USA Lehman College, CUNY, Bronx, NY 10468, USA The New York Botanical Garden, New York, NY 10458, USA Electronic address
    Fitoterapia 91:28-38. 2013
  2. doi request reprint Carnosic acid inhibits the growth of ER-negative human breast cancer cells and synergizes with curcumin
    Linda Saxe Einbond
    Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Fitoterapia 83:1160-8. 2012
  3. ncbi request reprint Chemopreventive potential of black cohosh on breast cancer in Sprague-Dawley rats
    Linda Saxe Einbond
    Department of Rehabilitation and Regenerative Medicine, College of Physicians and Surgeons, Columbia University, HHSC 1518, 701 W 168th Street, New York, NY 10032, USA
    Anticancer Res 32:21-30. 2012
  4. doi request reprint Pharmacological mechanisms of black cohosh in Sprague-Dawley rats
    Linda Saxe Einbond
    Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Fitoterapia 83:461-8. 2012
  5. doi request reprint Actein activates stress- and statin-associated responses and is bioavailable in Sprague-Dawley rats
    Linda Saxe Einbond
    Columbia Universty College of Physicians and Surgeons, New York, NY 10032, USA
    Fundam Clin Pharmacol 23:311-21. 2009
  6. ncbi request reprint Gene expression analysis of the mechanisms whereby black cohosh inhibits human breast cancer cell growth
    Linda Saxe Einbond
    Department of Rehabilitation Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Anticancer Res 27:697-712. 2007
  7. pmc Growth inhibitory activity of extracts and compounds from Cimicifuga species on human breast cancer cells
    Linda Saxe Einbond
    Department of Rehabilitation Medicine, Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, Columbia University, HHSC 1509, 701 W 168th Street, New York, NY 10032, USA
    Phytomedicine 15:504-11. 2008
  8. ncbi request reprint Actein and a fraction of black cohosh potentiate antiproliferative effects of chemotherapy agents on human breast cancer cells
    Linda Saxe Einbond
    Columbia University College of Physicians and Surgeons, 701 W 168th Street, New York, NY 10032, USA
    Planta Med 72:1200-6. 2006
  9. doi request reprint Actein inhibits the Na+-K+-ATPase and enhances the growth inhibitory effect of digitoxin on human breast cancer cells
    Linda Saxe Einbond
    Department of Rehabilitation Medicine, College of Physicians and Surgeons, Columbia University, HHSC 1508, 701 W 168th Street, New York, NY 10032, USA
    Biochem Biophys Res Commun 375:608-13. 2008
  10. ncbi request reprint The growth inhibitory effect of actein on human breast cancer cells is associated with activation of stress response pathways
    Linda Saxe Einbond
    Department of Rehabilitation Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Int J Cancer 121:2073-83. 2007

Detail Information

Publications13

  1. ncbi request reprint Actein induces calcium release in human breast cancer cells
    Linda Saxe Einbond
    Columbia University College of Physicians and Surgeons, New York, NY 10032, USA Lehman College, CUNY, Bronx, NY 10468, USA The New York Botanical Garden, New York, NY 10458, USA Electronic address
    Fitoterapia 91:28-38. 2013
    ..The ER IP3 receptor and Na,K-ATPase form a signaling microdomain. Since actein is lipophilic, its action may be limited by bioavailability...
  2. doi request reprint Carnosic acid inhibits the growth of ER-negative human breast cancer cells and synergizes with curcumin
    Linda Saxe Einbond
    Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Fitoterapia 83:1160-8. 2012
    ..Studies indicate that extracts and purified components, including carnosic acid, from the herb rosemary display significant growth inhibitory activity on a variety of cancers...
  3. ncbi request reprint Chemopreventive potential of black cohosh on breast cancer in Sprague-Dawley rats
    Linda Saxe Einbond
    Department of Rehabilitation and Regenerative Medicine, College of Physicians and Surgeons, Columbia University, HHSC 1518, 701 W 168th Street, New York, NY 10032, USA
    Anticancer Res 32:21-30. 2012
    ..This study examines the chemopreventive potential and action of the herb black cohosh on Sprague-Dawley rats...
  4. doi request reprint Pharmacological mechanisms of black cohosh in Sprague-Dawley rats
    Linda Saxe Einbond
    Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Fitoterapia 83:461-8. 2012
    ..Studies indicate that extracts and purified components from black cohosh inhibit the growth of human breast cancer cells, but the molecular targets and signaling pathways have not yet been defined...
  5. doi request reprint Actein activates stress- and statin-associated responses and is bioavailable in Sprague-Dawley rats
    Linda Saxe Einbond
    Columbia Universty College of Physicians and Surgeons, New York, NY 10032, USA
    Fundam Clin Pharmacol 23:311-21. 2009
    ..The serum level of actein peaked at 2.4 microg/mL at 6 h. Actein's ability to alter pathways involved in lipid disorders and carcinogenesis may make it a new agent for preventing and treating these major disorders...
  6. ncbi request reprint Gene expression analysis of the mechanisms whereby black cohosh inhibits human breast cancer cell growth
    Linda Saxe Einbond
    Department of Rehabilitation Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Anticancer Res 27:697-712. 2007
    ..Our aim is to identify alterations in gene expression induced by treatment with a methanolic extract (MeOH) of black cohosh...
  7. pmc Growth inhibitory activity of extracts and compounds from Cimicifuga species on human breast cancer cells
    Linda Saxe Einbond
    Department of Rehabilitation Medicine, Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, Columbia University, HHSC 1509, 701 W 168th Street, New York, NY 10032, USA
    Phytomedicine 15:504-11. 2008
    ....
  8. ncbi request reprint Actein and a fraction of black cohosh potentiate antiproliferative effects of chemotherapy agents on human breast cancer cells
    Linda Saxe Einbond
    Columbia University College of Physicians and Surgeons, 701 W 168th Street, New York, NY 10032, USA
    Planta Med 72:1200-6. 2006
    ....
  9. doi request reprint Actein inhibits the Na+-K+-ATPase and enhances the growth inhibitory effect of digitoxin on human breast cancer cells
    Linda Saxe Einbond
    Department of Rehabilitation Medicine, College of Physicians and Surgeons, Columbia University, HHSC 1508, 701 W 168th Street, New York, NY 10032, USA
    Biochem Biophys Res Commun 375:608-13. 2008
    ..Actein and digitoxin may be a useful synergistic combination for cancer chemoprevention and/or therapy...
  10. ncbi request reprint The growth inhibitory effect of actein on human breast cancer cells is associated with activation of stress response pathways
    Linda Saxe Einbond
    Department of Rehabilitation Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Int J Cancer 121:2073-83. 2007
    ..Since actein activated transcription factors that enhance apoptosis, and repressed cell cycle genes, it may be useful in the prevention and therapy of breast cancer...
  11. pmc Digitoxin activates EGR1 and synergizes with paclitaxel on human breast cancer cells
    Linda Saxe Einbond
    Columbia University College of Physicians and Surgeons, New York, NY, USA
    J Carcinog 9:10. 2010
    ..have used gene expression analysis to determine the molecular action of digitoxin on breast cancer cells and assessed digitoxin's ability to synergize with the chemotherapy agent paclitaxel with respect to inhibition of cell proliferation..
  12. ncbi request reprint Garcinia benzophenones inhibit the growth of human colon cancer cells and synergize with sulindac sulfide and turmeric
    Linda Saxe Einbond
    Lehman College and The Graduate Center, CUNY, Bronx, NY 10468, USA
    Anticancer Agents Med Chem 13:1540-50. 2013
    ..These studies indicate the potential of benzophenones, alone or combined with sulindac sulfide or turmeric, to prevent and treat colon cancer. ..
  13. ncbi request reprint Growth inhibitory activity of extracts and purified components of black cohosh on human breast cancer cells
    Linda Saxe Einbond
    Herbert Irvign Comperhensive Cancer Center, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Breast Cancer Res Treat 83:221-31. 2004
    ..Further studies are in progress to identify the mechanisms by which actein and related compounds present in black cohosh inhibit growth of human breast cancer cells...