Arnold E Eggers

Summary

Publications

  1. ncbi request reprint Suggestion for another anti-epileptic drug to use for migraine prophylaxis
    Arnold E Eggers
    Headache 42:696-7. 2002
  2. doi request reprint A suggestion about the cause of inflammation in acute atherosis complicating poor placentation in preeclampsia
    Arnold E Eggers
    SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, United States Kings County Hospital, 451 Clarkson Ave, Brooklyn, NY 11203, United States Electronic address
    Med Hypotheses 85:718-9. 2015
  3. doi request reprint A hypothesis about how to achieve anticoagulation without bleeding
    Arnold E Eggers
    SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, United States Kings County Hospital, 451 Clarkson Ave, Brooklyn, NY 11203, United States Electronic address
    Med Hypotheses 85:720-2. 2015
  4. doi request reprint A new theory of essential hypertension based on analysis of the association between a polymorphism of the α2-adrenoceptor at the 10q24-q26 locus and hypertension in African-Americans
    Arnold E Eggers
    SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, United States Kings County Hospital, 451 Clarkson Ave, Brooklyn, NY 11203, United States Electronic address
    Med Hypotheses 85:603-6. 2015
  5. doi request reprint A gedanken experiment to find a neuroanatomical model for post-traumatic stress disorder
    Arnold E Eggers
    SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, United States Kings County Hospital, 451 Clarkson Ave, Brooklyn, NY 11203, United States Electronic address
    Med Hypotheses 84:1-3. 2015
  6. doi request reprint Treatment of depression with deep brain stimulation works by altering in specific ways the conscious perception of the core symptoms of sadness or anhedonia, not by modulating network circuitry
    Arnold E Eggers
    SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, United States Kings County Hospital, 451 Clarkson Ave, Brooklyn, NY 11203, United States Electronic address
    Med Hypotheses 83:62-4. 2014
  7. doi request reprint An explanation of why schizophrenia begins with excitotoxic damage to the hippocampus
    Arnold E Eggers
    SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, United States Kings County Hospital, 451 Clarkson Ave, Brooklyn, NY 11203, United States Electronic address
    Med Hypotheses 81:1056-8. 2013
  8. doi request reprint A serotonin hypothesis of schizophrenia
    Arnold E Eggers
    SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, USA
    Med Hypotheses 80:791-4. 2013
  9. doi request reprint An explanation of how migraine headaches can trigger relapse in systemic lupus erythematosus
    Arnold E Eggers
    SUNY Downstate Medical Center, Department of Neurology, 450 Clarkson Ave, Box 1213, Brooklyn, NY 11203, USA
    Med Hypotheses 80:553-5. 2013
  10. doi request reprint Extending David Horrobin's membrane phospholipid theory of schizophrenia: overactivity of cytosolic phospholipase A(2) in the brain is caused by overdrive of coupled serotonergic 5HT(2A/2C) receptors in response to stress
    Arnold E Eggers
    SUNY Downstate Medical Center, Brooklyn, NY 11203, USA
    Med Hypotheses 79:740-3. 2012

Detail Information

Publications16

  1. ncbi request reprint Suggestion for another anti-epileptic drug to use for migraine prophylaxis
    Arnold E Eggers
    Headache 42:696-7. 2002
  2. doi request reprint A suggestion about the cause of inflammation in acute atherosis complicating poor placentation in preeclampsia
    Arnold E Eggers
    SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, United States Kings County Hospital, 451 Clarkson Ave, Brooklyn, NY 11203, United States Electronic address
    Med Hypotheses 85:718-9. 2015
    ..SPA is associated with migraine headaches, which are a prominent clinical feature of PE and may help explain why PE is a risk factor for future maternal cardiovascular disease. ..
  3. doi request reprint A hypothesis about how to achieve anticoagulation without bleeding
    Arnold E Eggers
    SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, United States Kings County Hospital, 451 Clarkson Ave, Brooklyn, NY 11203, United States Electronic address
    Med Hypotheses 85:720-2. 2015
    ..Thrombotic stroke is another possible indication for such a treatment. ..
  4. doi request reprint A new theory of essential hypertension based on analysis of the association between a polymorphism of the α2-adrenoceptor at the 10q24-q26 locus and hypertension in African-Americans
    Arnold E Eggers
    SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, United States Kings County Hospital, 451 Clarkson Ave, Brooklyn, NY 11203, United States Electronic address
    Med Hypotheses 85:603-6. 2015
    ..Renin levels fall pari passu with rising TPR caused by vascular remodeling. In the second stage of the disease, when renin has fallen back to normal (or low), increased TPR caused by vascular remodeling persists as a factor raising BP. ..
  5. doi request reprint A gedanken experiment to find a neuroanatomical model for post-traumatic stress disorder
    Arnold E Eggers
    SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, United States Kings County Hospital, 451 Clarkson Ave, Brooklyn, NY 11203, United States Electronic address
    Med Hypotheses 84:1-3. 2015
    ..e. through the interaction between pacemakers and processed sensory input from the outside world. It also directs pharmacological thinking to the role played by pacemakers and pacemaker currents. ..
  6. doi request reprint Treatment of depression with deep brain stimulation works by altering in specific ways the conscious perception of the core symptoms of sadness or anhedonia, not by modulating network circuitry
    Arnold E Eggers
    SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, United States Kings County Hospital, 451 Clarkson Ave, Brooklyn, NY 11203, United States Electronic address
    Med Hypotheses 83:62-4. 2014
    ..The response was not instantaneous but could begin within hours. In both cases, patients' realization that a core symptom had been relieved led to a moderate overall improvement in other symptoms...
  7. doi request reprint An explanation of why schizophrenia begins with excitotoxic damage to the hippocampus
    Arnold E Eggers
    SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, United States Kings County Hospital, 451 Clarkson Ave, Brooklyn, NY 11203, United States Electronic address
    Med Hypotheses 81:1056-8. 2013
    ..The remitting-relapsing pattern of schizophrenia is explained by a balance between excitotoxicity in the hippocampus and repopulation by neurogenesis in the subgranular zone. Injury is balanced by healing. ..
  8. doi request reprint A serotonin hypothesis of schizophrenia
    Arnold E Eggers
    SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, USA
    Med Hypotheses 80:791-4. 2013
    ..Normal dopamine input to an impaired ACC causes positive symptoms. Frontal lobe hibernation causes negative symptoms and cognitive impairment...
  9. doi request reprint An explanation of how migraine headaches can trigger relapse in systemic lupus erythematosus
    Arnold E Eggers
    SUNY Downstate Medical Center, Department of Neurology, 450 Clarkson Ave, Box 1213, Brooklyn, NY 11203, USA
    Med Hypotheses 80:553-5. 2013
    ..This eliminates the immunosuppressive hold of Tregs on self-reactive T cells and the development or worsening of autoimmune disease ensues spontaneously...
  10. doi request reprint Extending David Horrobin's membrane phospholipid theory of schizophrenia: overactivity of cytosolic phospholipase A(2) in the brain is caused by overdrive of coupled serotonergic 5HT(2A/2C) receptors in response to stress
    Arnold E Eggers
    SUNY Downstate Medical Center, Brooklyn, NY 11203, USA
    Med Hypotheses 79:740-3. 2012
    ..It also explains the role of stress in schizophrenia, elevated serum PLA(2) activity in schizophrenia, the relationship between untreated schizophrenia and metabolic syndrome, and the therapeutic rationale for EPA...
  11. doi request reprint Why do Alzheimer's disease and Parkinson's disease target the same neurons?
    Arnold E Eggers
    SUNY Downstate Medical Center, Department of Neurology, 450 Clarkson Ave, Box 1213, Brooklyn, NY 11203, USA
    Med Hypotheses 72:698-700. 2009
    ..The basic pathophysiological difference is that AD is caused by oxidative stress alone, whereas PD is caused by oxidative stress plus failure of energy production...
  12. ncbi request reprint Temporal lobe epilepsy is a disease of faulty neuronal resonators rather than oscillators, and all seizures are provoked, usually by stress
    Arnold E Eggers
    Department of Neurology, SUNY Downstate Medical Center, 450 Clarkson Avenue, Box 1213, Brooklyn, NY 11203, United States
    Med Hypotheses 69:1284-9. 2007
    ..The latter category includes several recognized anti-epileptic drugs. Drugs from all three categories should be used simultaneously and on an empirical basis in each patient...
  13. ncbi request reprint Redrawing Papez' circuit: a theory about how acute stress becomes chronic and causes disease
    Arnold E Eggers
    Department of Neurology, SUNY Downstate Medical Center, 450 Clarkson Avenue, Box 1213, Brooklyn, NY 11203, USA
    Med Hypotheses 69:852-7. 2007
    ..This leads to novel therapeutic recommendations, e.g. the use of ethosuximide, mood-stabilizers, and anti-depressants in synergy to treat essential hypertension...
  14. ncbi request reprint A chronic dysfunctional stress response can cause stroke by stimulating platelet activation, migraine, and hypertension
    A E Eggers
    Institution SUNY Downstate Medical Center, Box 1213, Department of Neurology, 450 Clarkson Avenue, Brooklyn, NY 11203, USA
    Med Hypotheses 65:542-5. 2005
    ....
  15. ncbi request reprint Neurological theory of hypertension
    A E Eggers
    Department of Neurology, SUNY Downstate Medical Center, Brooklyn, New York, USA
    Med Hypotheses 60:852-5. 2003
    ..This theory builds on a previously published neural theory of migraine...
  16. ncbi request reprint New neural theory of migraine
    A E Eggers
    Department of Neurology, SUNY-Health Science Center at Brooklyn, NY 11203, USA
    Med Hypotheses 56:360-3. 2001
    ..Excessive neuronal activation could cause migraine stroke by excitotoxicity and could explain the association of migraine with epilepsy. The serotonergic nuclei are positioned to mediate stress-induced migraine...