Arnold E Eggers

Summary

Publications

  1. ncbi request reprint Suggestion for another anti-epileptic drug to use for migraine prophylaxis
    Arnold E Eggers
    Headache 42:696-7. 2002
  2. ncbi request reprint Treatment of depression with deep brain stimulation works by altering in specific ways the conscious perception of the core symptoms of sadness or anhedonia, not by modulating network circuitry
    Arnold E Eggers
    SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, United States Kings County Hospital, 451 Clarkson Ave, Brooklyn, NY 11203, United States Electronic address
    Med Hypotheses 83:62-4. 2014
  3. ncbi request reprint An explanation of why schizophrenia begins with excitotoxic damage to the hippocampus
    Arnold E Eggers
    SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, United States Kings County Hospital, 451 Clarkson Ave, Brooklyn, NY 11203, United States Electronic address
    Med Hypotheses 81:1056-8. 2013
  4. doi request reprint A serotonin hypothesis of schizophrenia
    Arnold E Eggers
    SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, USA
    Med Hypotheses 80:791-4. 2013
  5. doi request reprint An explanation of how migraine headaches can trigger relapse in systemic lupus erythematosus
    Arnold E Eggers
    SUNY Downstate Medical Center, Department of Neurology, 450 Clarkson Ave, Box 1213, Brooklyn, NY 11203, USA
    Med Hypotheses 80:553-5. 2013
  6. doi request reprint Extending David Horrobin's membrane phospholipid theory of schizophrenia: overactivity of cytosolic phospholipase A(2) in the brain is caused by overdrive of coupled serotonergic 5HT(2A/2C) receptors in response to stress
    Arnold E Eggers
    SUNY Downstate Medical Center, Brooklyn, NY 11203, USA
    Med Hypotheses 79:740-3. 2012
  7. doi request reprint Why do Alzheimer's disease and Parkinson's disease target the same neurons?
    Arnold E Eggers
    SUNY Downstate Medical Center, Department of Neurology, 450 Clarkson Ave, Box 1213, Brooklyn, NY 11203, USA
    Med Hypotheses 72:698-700. 2009
  8. ncbi request reprint Temporal lobe epilepsy is a disease of faulty neuronal resonators rather than oscillators, and all seizures are provoked, usually by stress
    Arnold E Eggers
    Department of Neurology, SUNY Downstate Medical Center, 450 Clarkson Avenue, Box 1213, Brooklyn, NY 11203, United States
    Med Hypotheses 69:1284-9. 2007
  9. ncbi request reprint Redrawing Papez' circuit: a theory about how acute stress becomes chronic and causes disease
    Arnold E Eggers
    Department of Neurology, SUNY Downstate Medical Center, 450 Clarkson Avenue, Box 1213, Brooklyn, NY 11203, USA
    Med Hypotheses 69:852-7. 2007
  10. ncbi request reprint A chronic dysfunctional stress response can cause stroke by stimulating platelet activation, migraine, and hypertension
    A E Eggers
    Institution SUNY Downstate Medical Center, Box 1213, Department of Neurology, 450 Clarkson Avenue, Brooklyn, NY 11203, USA
    Med Hypotheses 65:542-5. 2005

Detail Information

Publications12

  1. ncbi request reprint Suggestion for another anti-epileptic drug to use for migraine prophylaxis
    Arnold E Eggers
    Headache 42:696-7. 2002
  2. ncbi request reprint Treatment of depression with deep brain stimulation works by altering in specific ways the conscious perception of the core symptoms of sadness or anhedonia, not by modulating network circuitry
    Arnold E Eggers
    SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, United States Kings County Hospital, 451 Clarkson Ave, Brooklyn, NY 11203, United States Electronic address
    Med Hypotheses 83:62-4. 2014
    ..The response was not instantaneous but could begin within hours. In both cases, patients' realization that a core symptom had been relieved led to a moderate overall improvement in other symptoms...
  3. ncbi request reprint An explanation of why schizophrenia begins with excitotoxic damage to the hippocampus
    Arnold E Eggers
    SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, United States Kings County Hospital, 451 Clarkson Ave, Brooklyn, NY 11203, United States Electronic address
    Med Hypotheses 81:1056-8. 2013
    ..The remitting-relapsing pattern of schizophrenia is explained by a balance between excitotoxicity in the hippocampus and repopulation by neurogenesis in the subgranular zone. Injury is balanced by healing. ..
  4. doi request reprint A serotonin hypothesis of schizophrenia
    Arnold E Eggers
    SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, USA
    Med Hypotheses 80:791-4. 2013
    ..Normal dopamine input to an impaired ACC causes positive symptoms. Frontal lobe hibernation causes negative symptoms and cognitive impairment...
  5. doi request reprint An explanation of how migraine headaches can trigger relapse in systemic lupus erythematosus
    Arnold E Eggers
    SUNY Downstate Medical Center, Department of Neurology, 450 Clarkson Ave, Box 1213, Brooklyn, NY 11203, USA
    Med Hypotheses 80:553-5. 2013
    ..This eliminates the immunosuppressive hold of Tregs on self-reactive T cells and the development or worsening of autoimmune disease ensues spontaneously...
  6. doi request reprint Extending David Horrobin's membrane phospholipid theory of schizophrenia: overactivity of cytosolic phospholipase A(2) in the brain is caused by overdrive of coupled serotonergic 5HT(2A/2C) receptors in response to stress
    Arnold E Eggers
    SUNY Downstate Medical Center, Brooklyn, NY 11203, USA
    Med Hypotheses 79:740-3. 2012
    ..It also explains the role of stress in schizophrenia, elevated serum PLA(2) activity in schizophrenia, the relationship between untreated schizophrenia and metabolic syndrome, and the therapeutic rationale for EPA...
  7. doi request reprint Why do Alzheimer's disease and Parkinson's disease target the same neurons?
    Arnold E Eggers
    SUNY Downstate Medical Center, Department of Neurology, 450 Clarkson Ave, Box 1213, Brooklyn, NY 11203, USA
    Med Hypotheses 72:698-700. 2009
    ..The basic pathophysiological difference is that AD is caused by oxidative stress alone, whereas PD is caused by oxidative stress plus failure of energy production...
  8. ncbi request reprint Temporal lobe epilepsy is a disease of faulty neuronal resonators rather than oscillators, and all seizures are provoked, usually by stress
    Arnold E Eggers
    Department of Neurology, SUNY Downstate Medical Center, 450 Clarkson Avenue, Box 1213, Brooklyn, NY 11203, United States
    Med Hypotheses 69:1284-9. 2007
    ..The latter category includes several recognized anti-epileptic drugs. Drugs from all three categories should be used simultaneously and on an empirical basis in each patient...
  9. ncbi request reprint Redrawing Papez' circuit: a theory about how acute stress becomes chronic and causes disease
    Arnold E Eggers
    Department of Neurology, SUNY Downstate Medical Center, 450 Clarkson Avenue, Box 1213, Brooklyn, NY 11203, USA
    Med Hypotheses 69:852-7. 2007
    ..This leads to novel therapeutic recommendations, e.g. the use of ethosuximide, mood-stabilizers, and anti-depressants in synergy to treat essential hypertension...
  10. ncbi request reprint A chronic dysfunctional stress response can cause stroke by stimulating platelet activation, migraine, and hypertension
    A E Eggers
    Institution SUNY Downstate Medical Center, Box 1213, Department of Neurology, 450 Clarkson Avenue, Brooklyn, NY 11203, USA
    Med Hypotheses 65:542-5. 2005
    ....
  11. ncbi request reprint Neurological theory of hypertension
    A E Eggers
    Department of Neurology, SUNY Downstate Medical Center, Brooklyn, New York, USA
    Med Hypotheses 60:852-5. 2003
    ..This theory builds on a previously published neural theory of migraine...
  12. ncbi request reprint New neural theory of migraine
    A E Eggers
    Department of Neurology, SUNY-Health Science Center at Brooklyn, NY 11203, USA
    Med Hypotheses 56:360-3. 2001
    ..Excessive neuronal activation could cause migraine stroke by excitotoxicity and could explain the association of migraine with epilepsy. The serotonergic nuclei are positioned to mediate stress-induced migraine...