Ori Efrati

Summary

Publications

  1. ncbi request reprint Primary meningococcal arthritis
    Ori Efrati
    Department of Pediatrics, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 4:386-7. 2002
  2. ncbi request reprint Liver cirrhosis and portal hypertension in cystic fibrosis
    Ori Efrati
    Paediatric Department, The Chaim Sheba Medical Centre, Tel Hashomer, Israel
    Eur J Gastroenterol Hepatol 15:1073-8. 2003
  3. ncbi request reprint Endobronchial adrenaline: should it be reconsidered? Dose response and haemodynamic effect in dogs
    Ori Efrati
    The Department of Pediatric Pulmonology, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel
    Resuscitation 59:117-22. 2003
  4. doi request reprint Meconium ileus in patients with cystic fibrosis is not a risk factor for clinical deterioration and survival: the Israeli Multicenter Study
    Ori Efrati
    Pediatric Pulmonary Unit, The Edmond and Lily Safra Children s Hospital, Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel
    J Pediatr Gastroenterol Nutr 50:173-8. 2010
  5. ncbi request reprint Beta1- or beta2-blockers to improve hemodynamics following endotracheal adrenaline administration
    Ron Ben-Abraham
    Department of Anesthesiology and Critical Care, Tel Aviv Sourasky Medical Center, Tel Hashomer, Israel
    Drug Metabol Drug Interact 21:31-9. 2005
  6. doi request reprint Flexible bronchoscopy and bronchoalveolar lavage in pediatric patients with lung disease
    Ori Efrati
    Pediatric Pulmonology Unit, Safra Children s Hospital, The Sheba Medical Center, Tel Hashomer, Israel
    Pediatr Crit Care Med 10:80-4. 2009
  7. ncbi request reprint Spirometry in early childhood in cystic fibrosis patients
    Daphna Vilozni
    Pediatric Pulmonary Unit, The Edmond and Lily Safra Children s Hospital, Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel, 52621
    Chest 131:356-61. 2007
  8. ncbi request reprint Exercise challenge test in 3- to 6-year-old asthmatic children
    Daphna Vilozni
    Pediatric Pulmonary Unit, The Edmond and Lily Safra Children s Hospital, Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan 52621, Israel
    Chest 132:497-503. 2007
  9. doi request reprint Outcome of patients with cystic fibrosis admitted to the intensive care unit: is invasive mechanical ventilation a risk factor for death in patients waiting lung transplantation?
    Ori Efrati
    Pediatric Pulmonology Unit, The Edmond and Lili Safra Children s Hospital, Sheba Medical Center Ramat Gan, Tel Hashomer 52621, Israel
    Heart Lung 39:153-9. 2010
  10. pmc Hospital versus home treatment of respiratory exacerbations in cystic fibrosis
    Moran Lavie
    Pediatric Pulmonary Unit and the National Center for Cystic Fibrosis, Edmond and Lily Safra Children Hospital, Sheba Medical Center, Tel Hashomer, Israel
    Med Sci Monit 17:CR698-703. 2011

Collaborators

Detail Information

Publications41

  1. ncbi request reprint Primary meningococcal arthritis
    Ori Efrati
    Department of Pediatrics, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 4:386-7. 2002
  2. ncbi request reprint Liver cirrhosis and portal hypertension in cystic fibrosis
    Ori Efrati
    Paediatric Department, The Chaim Sheba Medical Centre, Tel Hashomer, Israel
    Eur J Gastroenterol Hepatol 15:1073-8. 2003
    ..The aim of our study was to determine the prevalence, risk factors and invasive management of portal hypertension at our centre...
  3. ncbi request reprint Endobronchial adrenaline: should it be reconsidered? Dose response and haemodynamic effect in dogs
    Ori Efrati
    The Department of Pediatric Pulmonology, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel
    Resuscitation 59:117-22. 2003
    ..We hypothesized that endobronchial adrenaline administration is associated with better drug absorption, which may abolish the deleterious drop of blood pressure associated with tracheal drug administration...
  4. doi request reprint Meconium ileus in patients with cystic fibrosis is not a risk factor for clinical deterioration and survival: the Israeli Multicenter Study
    Ori Efrati
    Pediatric Pulmonary Unit, The Edmond and Lily Safra Children s Hospital, Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel
    J Pediatr Gastroenterol Nutr 50:173-8. 2010
    ..We evaluated the clinical characteristics and survival rates among Israeli patients with CF with and without MI after a prolonged follow-up (15-30 years)...
  5. ncbi request reprint Beta1- or beta2-blockers to improve hemodynamics following endotracheal adrenaline administration
    Ron Ben-Abraham
    Department of Anesthesiology and Critical Care, Tel Aviv Sourasky Medical Center, Tel Hashomer, Israel
    Drug Metabol Drug Interact 21:31-9. 2005
    ..We hypothesized that inhibition of the beta2-adrenoreceptors is responsible for prevention of the deleterious initial decrease in blood pressure that takes place following endotracheal administration of adrenaline...
  6. doi request reprint Flexible bronchoscopy and bronchoalveolar lavage in pediatric patients with lung disease
    Ori Efrati
    Pediatric Pulmonology Unit, Safra Children s Hospital, The Sheba Medical Center, Tel Hashomer, Israel
    Pediatr Crit Care Med 10:80-4. 2009
    ..Our aim was to study the diagnostic rate, safety, and clinical yield of FOB in critically ill pediatric patients...
  7. ncbi request reprint Spirometry in early childhood in cystic fibrosis patients
    Daphna Vilozni
    Pediatric Pulmonary Unit, The Edmond and Lily Safra Children s Hospital, Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel, 52621
    Chest 131:356-61. 2007
    ..Spirometry data in cystic fibrosis (CF) patients in early childhood is scarce, and the ability of spirometry to detect airways obstruction is debatable...
  8. ncbi request reprint Exercise challenge test in 3- to 6-year-old asthmatic children
    Daphna Vilozni
    Pediatric Pulmonary Unit, The Edmond and Lily Safra Children s Hospital, Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan 52621, Israel
    Chest 132:497-503. 2007
    ..The exercise challenge test (ECT) is a common tool to assess exercise-induced asthma (EIA) in school-aged children. EIA has not been explored in the early childhood setting...
  9. doi request reprint Outcome of patients with cystic fibrosis admitted to the intensive care unit: is invasive mechanical ventilation a risk factor for death in patients waiting lung transplantation?
    Ori Efrati
    Pediatric Pulmonology Unit, The Edmond and Lili Safra Children s Hospital, Sheba Medical Center Ramat Gan, Tel Hashomer 52621, Israel
    Heart Lung 39:153-9. 2010
    ..The admission of patients with cystic fibrosis (CF) to the intensive care unit (ICU) is controversial. Our aim was to study the long-term outcome of patients with CF who were admitted to the ICU and the effect of ventilation modality...
  10. pmc Hospital versus home treatment of respiratory exacerbations in cystic fibrosis
    Moran Lavie
    Pediatric Pulmonary Unit and the National Center for Cystic Fibrosis, Edmond and Lily Safra Children Hospital, Sheba Medical Center, Tel Hashomer, Israel
    Med Sci Monit 17:CR698-703. 2011
    ..Treatment of respiratory exacerbations in Cystic Fibrosis (CF) is important in slowing disease progression. The treatment may be given either at home or at the hospital. The aim of our study was to compare both treatment settings...
  11. ncbi request reprint Terlipressin as rescue therapy for intractable hypotension due to septic shock in children
    Ilan Matok
    Department of Pharmacy Services, Safra Children s Hospital, The Chaim Sheba Medical Center, Tel Hashomer, Israel
    Shock 23:305-10. 2005
    ..We conclude that terlipressin improves hemodynamic indices and renal function in critically ill children. Terlipressin should be considered as a rescue therapy in intractable shock not responsive to catecholamines in children...
  12. ncbi request reprint Improved survival following lung transplantation with long-term use of bilevel positive pressure ventilation in cystic fibrosis
    Ori Efrati
    Pediatric Pulmonology Unit, Safra Children s Hospital, The Chaim Sheba Medical Center, 25621, Tel Hashomer, Israel
    Lung 185:73-9. 2007
    ....
  13. doi request reprint The relation between age and time to maximal bronchoconstriction following exercise in children
    Daphna Vilozni
    Pediatric Pulmonary Unit, The Edmond and Lily Safra Children s Hospital, Sheba Medical Center, Tel Hashomer, Ramat Gan 52625, Affiliated to the Sackler Medical School, Tel Aviv University, Israel
    Respir Med 103:1456-60. 2009
    ..Such findings may influence epidemiological surveys where the schedule of post-exercise measurements is trimmed. This study systematically assesses the relation between age and time to maximal bronchoconstriction post-ECT...
  14. doi request reprint The changing face of the exocrine pancreas in cystic fibrosis: the correlation between pancreatic status, pancreatitis and cystic fibrosis genotype
    Arie Augarten
    CF Center, Chaim Sheba Medical Center, affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Hashomer, Israel
    Eur J Gastroenterol Hepatol 20:164-8. 2008
    ....
  15. ncbi request reprint Should vasopressin replace adrenaline for endotracheal drug administration?
    Ori Efrati
    Pediatric Intensive Care Unit, The Chaim Sheba Medical Center, Tel Hashomer, Israel
    Crit Care Med 31:572-6. 2003
    ..adrenaline on hemodynamic variables in a canine model, and we investigated whether vasopressin produces the same deleterious immediate blood pressure decrease as did endotracheal adrenaline in the canine model...
  16. doi request reprint Progressive flow-to-volume dysanapsis in cystic fibrosis: a predictor for lung transplantation?
    Daphna Vilozni
    Pediatric Pulmonary Unit, The Edmond and Lily Safra Children s Hospital, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel
    Am J Respir Crit Care Med 186:82-7. 2012
    ..Airways obstruction and lung volume restriction, major features of lung disease in cystic fibrosis (CF), may regress independently, causing dysanapsis between these parameters...
  17. ncbi request reprint Beneficial effects of terlipressin in prolonged pediatric cardiopulmonary resuscitation: a case series
    Ilan Matok
    Department of Pediatric Critical Care Medicine, Safra Children s Hospital, Sheba Medical Center, Tel Hashomer, Israel
    Crit Care Med 35:1161-4. 2007
    ..The objective of this retrospective study is to describe our experience in adding terlipressin to the conventional protocol in children with cardiac arrest...
  18. ncbi request reprint Neurologic presentation in children with ataxia-telangiectasia: is small head circumference a hallmark of the disease?
    Andreea Nissenkorn
    National A T Clinic, Edmond and Lilly Safra Children s Hospital, Sheba Medical Center, Ramat Gan, Israel
    J Pediatr 159:466-471.e1. 2011
    ..To define the neurologic characteristics and course of ataxia-telangiectasia (A-T)...
  19. ncbi request reprint Long term nutritional rehabilitation by gastrostomy in Israeli patients with cystic fibrosis: clinical outcome in advanced pulmonary disease
    Ori Efrati
    Pediatric Pulmonary Unit, The Safra Children s Hospital, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel
    J Pediatr Gastroenterol Nutr 42:222-8. 2006
    ..Our study aims were: 1) To evaluate the effect of nutritional supplementation via gastrostomy on nutritional, clinical, and pulmonary parameters, and 2) To identify predicting factors for success of long-term nutritional rehabilitation...
  20. ncbi request reprint Atropine aborts bradycardic effect of endotracheally administered vasopressin
    Ori Efrati
    Departemnt of Pediatric Pulmonology, of the Chaim Sheba Medical Center, Tel Hashomer, Israel
    Med Sci Monit 11:CR410-4. 2005
    ..However, vasopressin can cause significant bradycardia, resulting in reduced cardiac output. We investigated whether pre-treatment with atropine abrogates vasopressin-induced bradycardia in a beating-heart canine model...
  21. ncbi request reprint Spirometry follow-up in young children with hemato-oncologic diseases
    Ori Efrati
    Pediatric Pulmonary Unit, The Edmond and Lili Safra Children s Hospital, Sheba Medical Center, Ramat Gan, Israel, 52621
    Med Sci Monit 16:MT28-33. 2010
    ..Aim: To assess severity of airway disease using forced spirometry measured prior to and after treatment (over 3 years) in hemato-oncologic children aged 3-7 years in comparison to a healthy population...
  22. doi request reprint Reversible airway obstruction in children with ataxia telangiectasia
    Yackov Berkun
    Ataxia Telangiectasia National Clinic, Chaim Sheba Medical Center, Tel Hashomer, Affiliated with the Sackler Medical School, Tel Aviv University, Israel
    Pediatr Pulmonol 45:230-5. 2010
    ..Lung disease is a significant cause of the short life span of ataxia telangiectasia (A-T) patients. Objective lung function measurements are difficult to achieve in A-T...
  23. doi request reprint The feasibility and validity of forced spirometry in ataxia telangiectasia
    Daphna Vilozni
    The Pediatric Pulmonary Unit, The Edmond and Lily Safra Children s Hospital, Sheba Medical Center, Ramat Gan, affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Pediatr Pulmonol 45:1030-6. 2010
    ..To explore the feasibility and validity of forced spirometry in patients with ataxia telangiectasia (A-T)...
  24. ncbi request reprint Probiotic supplementation affects pulmonary exacerbations in patients with cystic fibrosis: a pilot study
    Batia Weiss
    Division of Pediatric Gastroenterology and Nutrition, Safra Children s Hospital, Tel Hashomer, Israel
    Pediatr Pulmonol 45:536-40. 2010
    ..We intended to determine the effect of a mixed probiotic preparation on pulmonary exacerbations and inflammatory characteristics of the sputum in CF patients...
  25. ncbi request reprint N-terminal pro B-type natriuretic peptide (N-BNP) levels in cystic fibrosis patients
    Amir Ben Tov
    CF Center, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Pediatr Pulmonol 42:699-703. 2007
    ..However, its level was never measured in CF patients. The aim of this study was to measure N-BNP level in CF patients without heart failure...
  26. ncbi request reprint Long-term non-invasive positive pressure ventilation among cystic fibrosis patients awaiting lung transplantation
    Ori Efrati
    Pediatric Pulmonary Unit, Safra Children s Hospital, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 6:527-30. 2004
    ..New techniques such as non-invasive positive pressure ventilation have resulted in prolongation of life expectancy in CF patients with end-stage lung disease...
  27. ncbi request reprint Pregnancies and outcome in women with cystic fibrosis
    Asher Barak
    National Cystic Fibrosis Center, Safra Children s Hospital, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 7:95-8. 2005
    ..These include infertility, severity of lung disease, pancreatic insufficiency, poor nutritional status, glucose intolerance and diabetes, drug safety, and long-term maternal and neonatal outcome...
  28. ncbi request reprint Intravenous arginine vasopressin in critically ill children: is it beneficial?
    Ori Efrati
    Pediatric Pulmonary Unit, The Chaim Sheba Medical Center, Tel Hashomer, Israel
    Shock 22:213-7. 2004
    ..We hypothesize that earlier administration of AVP may be more beneficial...
  29. doi request reprint Patterns and prognostic value of troponin, interleukin-6, and leptin after pediatric open-heart surgery
    Dalit Modan-Moses
    Pediatric Endocrinology Unit, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel
    J Crit Care 24:419-25. 2009
    ..We investigated changes in leptin, IL-6, and troponin in children undergoing open-heart surgery, hypothesizing that IL-6 and troponin will increase after cardiopulmonary bypass (CPB) and will be negatively correlated with leptin...
  30. ncbi request reprint The role of flexible fibreoptic bronchoscopy in evaluation of pulmonary diseases in children with congenital cardiac disease
    Ori Efrati
    Pediatric Pulmonology Unit, Safra Children s Hospital, The Sheba Medical Center, Tel Hashomer, Israel
    Cardiol Young 17:140-4. 2007
    ..A definite diagnosis may be achieved by fibreoptic flexible bronchoscopy...
  31. ncbi request reprint Disturbed B and T cell homeostasis and neogenesis in patients with ataxia telangiectasia
    Matan Kraus
    Pediatric Immunology Unit, Jeffrey Modell Foundation JMF Center and Department of Pediatrics, Sheba Medical Center, Tel Hashomer, Israel
    J Clin Immunol 34:561-72. 2014
    ..We examined immunologic parameters reflecting cell development and proliferation and their relevancy to the clinical phenotype in affected individuals...
  32. ncbi request reprint The role of computer games in measuring spirometry in healthy and "asthmatic" preschool children
    Daphna Vilozni
    Pediatric Pulmonary Unit, The Edmond and Lily Safra Children s Hospital, Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan 52625, Israel
    Chest 128:1146-55. 2005
    ....
  33. ncbi request reprint Reversal of digital clubbing after lung transplantation in cystic fibrosis patients: a clue to the pathogenesis of clubbing
    Arie Augarten
    National Center for Cystic Fibrosis, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Pediatr Pulmonol 34:378-80. 2002
    ..This could be explained either by adequate inactivation of a circulating clubbing-inducing molecule by the normal transplanted lungs, or by removal of the diseased lungs in which this presumably causative substance was produced...
  34. doi request reprint Molecular assessment of thymus capabilities in the evaluation of T-cell immunodeficiency
    Ninette Amariglio
    Cancer Research Center, Safra Children s Hospital, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel
    Pediatr Res 67:211-6. 2010
    ..Assessment of thymus capabilities by TRECs and TCR repertoire analyses is helpful in diagnosing patients with T-cell immunodeficiency and should be part of the evaluation of every patient suspected of having that condition...
  35. ncbi request reprint Intractable hypotension in septic shock: successful treatment with vasopressin in an infant
    Leah Leibovitch
    Department of Pediatric Intensive Care, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 5:596-8. 2003
  36. ncbi request reprint Peak bone mass in patients with phenylketonuria
    D Modan-Moses
    Pediatric Endocrinology Unit, The Edmond and Lily Safra Children s Hospital, Tel Hashomer, 52621, Israel
    J Inherit Metab Dis 30:202-8. 2007
    ..Our aim was to evaluate peak bone mass in adult PKU patients and to relate BMD to nutritional parameters...
  37. ncbi request reprint Pleural effusions in the pediatric population
    Ori Efrati
    The Pediatrics Pulmonary Unit, Sheba Medical Center, Tel Hashomer Hospital, Ramat Gan, Israel
    Pediatr Rev 23:417-26. 2002
  38. ncbi request reprint Endotracheal epinephrine: a call for larger doses
    Yossi Manisterski
    Department of Pediatric Intensive Care, The Chaim Sheba Medical Center, Tel Hashomer and the Sackler Faculty of Medicine, Tel Aviv University, Israel
    Anesth Analg 95:1037-41, table of contents. 2002
    ..Only the 0.3 mg/kg dose successfully caused an increase in BP, observed 2 min after administration, and lasting for 10 min. An early decrease in BP was obviated only at a dose equivalent to 10-fold the currently recommended one...
  39. ncbi request reprint Tracheal epinephrine or norepinephrine preceded by beta blockade in a dog model. Can beta blockade bestow any benefits?
    Arnon Elizur
    The Department of Pediatric Intensive Care, The Chaim Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel
    Resuscitation 59:271-6. 2003
    ..At the same time, the pretreatment augmented the relatively mild diastolic BP increase associated with the beta-adrenergic effect of epinephrine...
  40. doi request reprint Pulmonary function studies in children treated by chemoradiotherapy and stem cell transplantation
    Ori Efrati
    Pediatric Pulmonary Unit, The Edmond and Lili Safra Children s Hospital, Sheba Medical Center affiliated with Sackler School of Medicine, Tel Aviv University, Ramat Gan, Israel
    Pediatr Blood Cancer 51:684-8. 2008
    ..We assessed pulmonary function at diagnosis and during a 5-year follow-up to identify risk factors associated with pulmonary deterioration...
  41. ncbi request reprint Lung transplantation in patients with cystic fibrosis: the Israeli experience
    Dario Prais
    Pulmonary Institute, Rabin Medical Center, Petah Tikva, Israel
    Isr Med Assoc J 8:396-9. 2006
    ..Although it confers a clear survival advantage, outcome differs among centers according to local experience, patient selection, transplantation procedure, and postoperative care...