Eran Eden

Summary

Publications

  1. pmc GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists
    Eran Eden
    Molecular Cell Biology Department, Weizmann Institute of Science, Rehovot, Israel
    BMC Bioinformatics 10:48. 2009
  2. doi request reprint Proteome half-life dynamics in living human cells
    Eran Eden
    Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel
    Science 331:764-8. 2011
  3. doi request reprint Using bleach-chase to measure protein half-lives in living cells
    Naama Geva-Zatorsky
    Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel
    Nat Protoc 7:801-11. 2012
  4. pmc Dynamic proteomics of human protein level and localization across the cell cycle
    Shlomit Farkash-Amar
    Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel
    PLoS ONE 7:e48722. 2012
  5. pmc Noise genetics: inferring protein function by correlating phenotype with protein levels and localization in individual human cells
    Shlomit Farkash-Amar
    Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel
    PLoS Genet 10:e1004176. 2014
  6. pmc Dynamic Proteomics: a database for dynamics and localizations of endogenous fluorescently-tagged proteins in living human cells
    Milana Frenkel-Morgenstern
    Molecular Cell Biology Department, Bioinformatics Unit, Weizmann Institute of Science, Rehovot 76100, Israel
    Nucleic Acids Res 38:D508-12. 2010
  7. pmc Generation of double-labeled reporter cell lines for studying co-dynamics of endogenous proteins in individual human cells
    Irina Issaeva
    Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel
    PLoS ONE 5:e13524. 2010
  8. doi request reprint Central carbon metabolism as a minimal biochemical walk between precursors for biomass and energy
    Elad Noor
    Department of Plant Sciences, Weizmann Institute of Science, Rehovot 76100, Israel
    Mol Cell 39:809-20. 2010

Collaborators

Detail Information

Publications8

  1. pmc GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists
    Eran Eden
    Molecular Cell Biology Department, Weizmann Institute of Science, Rehovot, Israel
    BMC Bioinformatics 10:48. 2009
    ..A few tools also exist that support analyzing ranked lists. The latter typically rely on simulations or on union-bound correction for assigning statistical significance to the results...
  2. doi request reprint Proteome half-life dynamics in living human cells
    Eran Eden
    Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel
    Science 331:764-8. 2011
    ..This approach opens a way to understand proteome half-life dynamics in living cells...
  3. doi request reprint Using bleach-chase to measure protein half-lives in living cells
    Naama Geva-Zatorsky
    Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel
    Nat Protoc 7:801-11. 2012
    ..The duration of the protocol is 4-5 d. The method may be applicable to a wide range of fluorescently tagged proteins and cell lines...
  4. pmc Dynamic proteomics of human protein level and localization across the cell cycle
    Shlomit Farkash-Amar
    Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel
    PLoS ONE 7:e48722. 2012
    ..Most of the cell-cycle dependent proteins exhibit changes in cellular localization. Such changes can be a useful tool in the regulation of the cell-cycle being fast and efficient...
  5. pmc Noise genetics: inferring protein function by correlating phenotype with protein levels and localization in individual human cells
    Shlomit Farkash-Amar
    Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel
    PLoS Genet 10:e1004176. 2014
    ..We recovered 30 known motility genes, and validated several novel ones by mild knockdown experiments. Noise genetics can complement standard genetics for a variety of phenotypes. ..
  6. pmc Dynamic Proteomics: a database for dynamics and localizations of endogenous fluorescently-tagged proteins in living human cells
    Milana Frenkel-Morgenstern
    Molecular Cell Biology Department, Bioinformatics Unit, Weizmann Institute of Science, Rehovot 76100, Israel
    Nucleic Acids Res 38:D508-12. 2010
    ..The raw movies may be useful as a benchmark for developing image analysis tools for individual-cell dynamic-proteomics. The database is available at http://www.dynamicproteomics.net/...
  7. pmc Generation of double-labeled reporter cell lines for studying co-dynamics of endogenous proteins in individual human cells
    Irina Issaeva
    Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel
    PLoS ONE 5:e13524. 2010
    ..Thus, our approach provides an efficient tool for studying dynamic relationship between components of systems of interest at a single-cell level...
  8. doi request reprint Central carbon metabolism as a minimal biochemical walk between precursors for biomass and energy
    Elad Noor
    Department of Plant Sciences, Weizmann Institute of Science, Rehovot 76100, Israel
    Mol Cell 39:809-20. 2010
    ..This suggests an optimality principle for the structure of central carbon metabolism. The present approach may be used to study other metabolic networks and to design new minimal pathways...