Christophe J Echeverri

Summary

Publications

  1. ncbi High-throughput RNAi screening in cultured cells: a user's guide
    Christophe J Echeverri
    Cenix BioScience GmbH, Tatzberg 47, Dresden 01307, Germany
    Nat Rev Genet 7:373-84. 2006
  2. ncbi High-throughput RNA interference strategies for target discovery and validation by using synthetic short interfering RNAs: functional genomics investigations of biological pathways
    Christoph Sachse
    Cenix BioScience GmbH, Dreseden, Germany
    Methods Enzymol 392:242-77. 2005
  3. ncbi Minimizing the risk of reporting false positives in large-scale RNAi screens
    Christophe J Echeverri
    Cenix BioScience GmbH, Tatzberg 47, Dresden, 10307, Germany
    Nat Methods 3:777-9. 2006
  4. ncbi Oncology studies using siRNA libraries: the dawn of RNAi-based genomics
    Christoph Sachse
    Cenix BioScience GmbH, Tatzberg 47, 01307 Dresden, Germany
    Oncogene 23:8384-91. 2004
  5. ncbi Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis
    Kristin C Gunsalus
    Center for Comparative Functional Genomics, Department of Biology, New York University, New York, New York 10003, USA
    Nature 436:861-5. 2005
  6. ncbi In situ fluorescence analysis demonstrates active siRNA exclusion from the nucleus by Exportin 5
    Thomas Ohrt
    Institute for Biophysics, BIOTEC, Dresden University of Technology, Tatzberg 47-51, 01307 Dresden, Germany
    Nucleic Acids Res 34:1369-80. 2006

Collaborators

Detail Information

Publications6

  1. ncbi High-throughput RNAi screening in cultured cells: a user's guide
    Christophe J Echeverri
    Cenix BioScience GmbH, Tatzberg 47, Dresden 01307, Germany
    Nat Rev Genet 7:373-84. 2006
    ....
  2. ncbi High-throughput RNA interference strategies for target discovery and validation by using synthetic short interfering RNAs: functional genomics investigations of biological pathways
    Christoph Sachse
    Cenix BioScience GmbH, Dreseden, Germany
    Methods Enzymol 392:242-77. 2005
    ..This chapter discusses technical aspects of how to perform such screens, what parameters to monitor, and which readouts to apply. Examples of homogenous assays and multiplexed high-content microscopy-based screens are demonstrated...
  3. ncbi Minimizing the risk of reporting false positives in large-scale RNAi screens
    Christophe J Echeverri
    Cenix BioScience GmbH, Tatzberg 47, Dresden, 10307, Germany
    Nat Methods 3:777-9. 2006
    ....
  4. ncbi Oncology studies using siRNA libraries: the dawn of RNAi-based genomics
    Christoph Sachse
    Cenix BioScience GmbH, Tatzberg 47, 01307 Dresden, Germany
    Oncogene 23:8384-91. 2004
    ..Here, we discuss the basic design issues, potential advantages, and technical challenges of large-scale RNAi screens based on the use of chemically synthesized siRNA libraries...
  5. ncbi Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis
    Kristin C Gunsalus
    Center for Comparative Functional Genomics, Department of Biology, New York University, New York, New York 10003, USA
    Nature 436:861-5. 2005
    ..We assessed the overall predictive value of such molecular machine models by dynamic localization of ten previously uncharacterized proteins within the living embryo...
  6. ncbi In situ fluorescence analysis demonstrates active siRNA exclusion from the nucleus by Exportin 5
    Thomas Ohrt
    Institute for Biophysics, BIOTEC, Dresden University of Technology, Tatzberg 47-51, 01307 Dresden, Germany
    Nucleic Acids Res 34:1369-80. 2006
    ..Exportin 5 therefore represents a key point of intersection between the siRNA and miRNA pathways, and, as such, is of fundamental importance for the design and interpretation of RNA interference experimentation...