Richard P Ebstein

Summary

Publications

  1. doi request reprint The contributions of oxytocin and vasopressin pathway genes to human behavior
    Richard P Ebstein
    Department of Psychology, National University of Singapore, Singapore
    Horm Behav 61:359-79. 2012
  2. pmc Copy number variation of the SELENBP1 gene in schizophrenia
    Shirly Amar
    Psychiatry Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, and Mental Health Center, Beersheva, Israel
    Behav Brain Funct 6:40. 2010
  3. doi request reprint Are retinoids potential therapeutic agents in disorders of social cognition including autism?
    Richard P Ebstein
    Department of Psychology, Faculty of Arts and Sciences, National University of Singapore, Singapore
    FEBS Lett 585:1529-36. 2011
  4. pmc All-trans retinoic acid upregulates reduced CD38 transcription in lymphoblastoid cell lines from Autism spectrum disorder
    Mathias Riebold
    Department of Human Genetics, Hebrew University, Jerusalem, Israel
    Mol Med 17:799-806. 2011
  5. doi request reprint Genetics of human social behavior
    Richard P Ebstein
    Department of Psychology, The Hebrew University of Jerusalem, Jerusalem 91905, Israel
    Neuron 65:831-44. 2010
  6. doi request reprint Molecular genetic studies of the arginine vasopressin 1a receptor (AVPR1a) and the oxytocin receptor (OXTR) in human behaviour: from autism to altruism with some notes in between
    Salomon Israel
    Department of Psychology, The Hebrew University of Jerusalem, Jerusalem, Israel
    Prog Brain Res 170:435-49. 2008
  7. ncbi request reprint Anorexia nervosa, perfectionism, and dopamine D4 receptor (DRD4)
    Rachel Bachner-Melman
    Department of Psychology, Mount Scopus, Hebrew University, Jerusalem, Israel
    Am J Med Genet B Neuropsychiatr Genet 144:748-56. 2007
  8. pmc Epigenetic and genetic factors predict women's salivary cortisol following a threat to the social self
    Shany Edelman
    Department of Neurobiology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    PLoS ONE 7:e48597. 2012
  9. doi request reprint Low CD38 expression in lymphoblastoid cells and haplotypes are both associated with autism in a family-based study
    Elad Lerer
    Human Genetics, Hebrew University, Jerusalem, Israel
    Autism Res 3:293-302. 2010
  10. doi request reprint Boys' serotonin transporter genotype affects maternal behavior through self-control: a case of evocative gene-environment correlation
    Roni Pener-Tessler
    Hebrew University of Jerusalem, Mount Scopus, Jerusalem 91905, Israel
    Dev Psychopathol 25:151-62. 2013

Collaborators

Detail Information

Publications42

  1. doi request reprint The contributions of oxytocin and vasopressin pathway genes to human behavior
    Richard P Ebstein
    Department of Psychology, National University of Singapore, Singapore
    Horm Behav 61:359-79. 2012
    ..This article is part of a Special Issue entitled Oxytocin, Vasopressin, and Social Behavior...
  2. pmc Copy number variation of the SELENBP1 gene in schizophrenia
    Shirly Amar
    Psychiatry Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, and Mental Health Center, Beersheva, Israel
    Behav Brain Funct 6:40. 2010
    ..We hypothesized that CN mutations in the SELENBP1 locus could associate with the disorder and that these mutations could alter the gene product's activity in patients...
  3. doi request reprint Are retinoids potential therapeutic agents in disorders of social cognition including autism?
    Richard P Ebstein
    Department of Psychology, Faculty of Arts and Sciences, National University of Singapore, Singapore
    FEBS Lett 585:1529-36. 2011
    ....
  4. pmc All-trans retinoic acid upregulates reduced CD38 transcription in lymphoblastoid cell lines from Autism spectrum disorder
    Mathias Riebold
    Department of Human Genetics, Hebrew University, Jerusalem, Israel
    Mol Med 17:799-806. 2011
    ..In conclusion, our results provide an empirical basis for the development of a pharmacological ASD treatment strategy based on retinoids...
  5. doi request reprint Genetics of human social behavior
    Richard P Ebstein
    Department of Psychology, The Hebrew University of Jerusalem, Jerusalem 91905, Israel
    Neuron 65:831-44. 2010
    ..Other polymorphic genes constituting the "usual suspects"--i.e., those encoding for dopamine reward pathways, serotonergic emotional regulation, or sex hormones--further enable elaborate social behaviors...
  6. doi request reprint Molecular genetic studies of the arginine vasopressin 1a receptor (AVPR1a) and the oxytocin receptor (OXTR) in human behaviour: from autism to altruism with some notes in between
    Salomon Israel
    Department of Psychology, The Hebrew University of Jerusalem, Jerusalem, Israel
    Prog Brain Res 170:435-49. 2008
    ..Ultimately, investigators should strive to develop a cohesive model explaining how genomic variations are translated into individual and group differences in higher-order social behaviours...
  7. ncbi request reprint Anorexia nervosa, perfectionism, and dopamine D4 receptor (DRD4)
    Rachel Bachner-Melman
    Department of Psychology, Mount Scopus, Hebrew University, Jerusalem, Israel
    Am J Med Genet B Neuropsychiatr Genet 144:748-56. 2007
    ..Personality traits are potential endophenotypes for understanding the etiology of eating disorders and one of the several pathways to eating pathology may be mediated by the impact of DNA sequences on perfectionism...
  8. pmc Epigenetic and genetic factors predict women's salivary cortisol following a threat to the social self
    Shany Edelman
    Department of Neurobiology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    PLoS ONE 7:e48597. 2012
    ....
  9. doi request reprint Low CD38 expression in lymphoblastoid cells and haplotypes are both associated with autism in a family-based study
    Elad Lerer
    Human Genetics, Hebrew University, Jerusalem, Israel
    Autism Res 3:293-302. 2010
    ..This prompted us to both examine CD38 expression in human lymphoblastoid cell lines (LBC) as well as to test association between SNPs across the CD38 gene and ASD...
  10. doi request reprint Boys' serotonin transporter genotype affects maternal behavior through self-control: a case of evocative gene-environment correlation
    Roni Pener-Tessler
    Hebrew University of Jerusalem, Mount Scopus, Jerusalem 91905, Israel
    Dev Psychopathol 25:151-62. 2013
    ..The implications of this evocative gene-environment correlation and the observed sex differences are discussed...
  11. pmc AVPR1A variant associated with preschoolers' lower altruistic behavior
    Reut Avinun
    Department of Neurobiology, The Hebrew University of Jerusalem, Jerusalem, Israel
    PLoS ONE 6:e25274. 2011
    ..This finding helps further the understanding of the intricate mechanisms underlying early altruistic behavior...
  12. pmc Dopamine D4 receptor gene associated with fairness preference in ultimatum game
    Songfa Zhong
    Department of Economics, National University of Singapore, Singapore, Singapore
    PLoS ONE 5:e13765. 2010
    ..This is the first result to link preference for reciprocal fairness to a specific gene and suggests that gene × environment interactions contribute to economic decision making...
  13. pmc The oxytocin receptor (OXTR) contributes to prosocial fund allocations in the dictator game and the social value orientations task
    Salomon Israel
    Department of Psychology, The Hebrew University of Jerusalem, Jerusalem, Israel
    PLoS ONE 4:e5535. 2009
    ..In the current investigation, the gene encoding the related oxytocin receptor (OXTR) was tested for association with the DG and a related paradigm, the Social Values Orientation (SVO) task...
  14. doi request reprint Vasopressin needs an audience: neuropeptide elicited stress responses are contingent upon perceived social evaluative threats
    Idan Shalev
    Neurobiology, Hebrew University, Jerusalem, 91501, Israel
    Horm Behav 60:121-7. 2011
    ....
  15. doi request reprint Defensive self-presentation style is associated with reduced prepulse inhibition
    Raz Levin
    Ezrath Nashim Herzog Memorial Hospital, Jerusalem, Israel
    Eur Neuropsychopharmacol 21:810-3. 2011
    ..Its findings suggest that very basic perceptual deficits that can be assessed using the PPI paradigm, may reflect information processing abnormalities that impact negatively upon the perception of complex social interactions...
  16. pmc AVPR1a and SLC6A4 gene polymorphisms are associated with creative dance performance
    Rachel Bachner-Melman
    Department of Psychology, Mount Scopus, Hebrew University, Jerusalem, Israel
    PLoS Genet 1:e42. 2005
    ....
  17. doi request reprint Association between arginine vasopressin 1a receptor (AVPR1a) promoter region polymorphisms and prepulse inhibition
    Raz Levin
    Neurobiology, Hebrew University, Jerusalem, Israel
    Psychoneuroendocrinology 34:901-8. 2009
    ..This is the first report in humans demonstrating a role of the AVPR1a gene in contributing to the PPI response to auditory stimuli...
  18. ncbi request reprint An examination of cognitive versus behavioral components of recovery from anorexia nervosa
    Rachel Bachner-Melman
    Department of Psychiatry, Hadassah University Medical Center, Ein Kerem, Jerusalem, Israel
    J Nerv Ment Dis 194:697-703. 2006
    ....
  19. doi request reprint BDNF Val66Met polymorphism is associated with HPA axis reactivity to psychological stress characterized by genotype and gender interactions
    Idan Shalev
    Neurobiology, Hebrew University, Jerusalem, Israel
    Psychoneuroendocrinology 34:382-8. 2009
    ..Gender differences in BDNFxstress responses were posited because estrogen induces synthesis of BDNF in several brain regions...
  20. pmc Human maternal behaviour is associated with arginine vasopressin receptor 1A gene
    Reut Avinun
    Department of Psychology, The Hebrew University of Jerusalem, Mount Scopus, Jerusalem 91905, Israel
    Biol Lett 8:894-6. 2012
    ..This finding advances our understanding of the genetic influences on human maternal behaviour...
  21. ncbi request reprint Association between a vasopressin receptor AVPR1A promoter region microsatellite and eating behavior measured by a self-report questionnaire (Eating Attitudes Test) in a family-based study of a nonclinical population
    Rachel Bachner-Melman
    Department of Psychology, Mount Scopus, Hebrew University, Jerusalem, Israel
    Int J Eat Disord 36:451-60. 2004
    ....
  22. pmc Differential genetic susceptibility to child risk at birth in predicting observed maternal behavior
    Keren Fortuna
    Department of Psychology, The Hebrew University of Jerusalem, Jerusalem, Israel
    PLoS ONE 6:e19765. 2011
    ....
  23. doi request reprint Arginine vasopressin and oxytocin modulate human social behavior
    Richard P Ebstein
    Department of Psychology, The Hebrew University of Jerusalem, Herzog Memorial Hospital, Givat Shaul, Jerusalem, Israel
    Ann N Y Acad Sci 1167:87-102. 2009
    ..We expect that future studies will continue this advance and deepen our understanding of these complex events...
  24. ncbi request reprint Association between the insulin-like growth factor 2 gene (IGF2) and scores on the Eating Attitudes Test in nonclinical subjects: a family-based study
    Rachel Bachner-Melman
    Scheinfeld Center for Human Genetics in the Social Sciences, Department of Psychology, Hebrew University, Jerusalem 91905, Israel
    Am J Psychiatry 162:2256-62. 2005
    ..This investigation extended these studies and investigated the psychological and behavioral implications of this hormone's impact on metabolism and body composition...
  25. doi request reprint Mothers' dopamine receptor polymorphism modulates the relation between infant fussiness and sensitive parenting
    Marsha Kaitz
    Department of Psychology, Hebrew University, Jerusalem 91905, Israel
    Dev Psychobiol 52:149-57. 2010
    ..Among those parents, sensitivity did not vary with infant temperament. This pattern of results indicates that mothers are differentially susceptible to infant fussiness, dependent on the presence of the 7-repeat DRD4 allele...
  26. ncbi request reprint The oxytocin receptor (OXTR) contributes to prosocial fund allocations in the dictator game and the social value orientations task
    Salomon Israel
    Department of Psychology, The Hebrew University of Jerusalem, Jerusalem, Israel
    PLoS ONE 4:e5535. 2009
    ....
  27. doi request reprint Oxytocin, but not vasopressin, increases both parochial and universal altruism
    Salomon Israel
    Department of Psychology and Center for the Study of Rationality, Hebrew University, Jerusalem 91501, Israel
    Psychoneuroendocrinology 37:1341-4. 2012
    ..In contrast, participants receiving vasopressin did not differ from those receiving placebo in their cooperative behavior. Our results highlight the selective role of oxytocin in intergroup cooperative behavior...
  28. doi request reprint Hypnotizability is associated with a protective but not acquisitive self-presentation style
    Raz Levin
    Herzog Memorial Hospital, Jerusalem, Israel
    Int J Clin Exp Hypn 61:183-92. 2013
    ..43, p = .002) but not between hypnotizability and RSMS (r = .070, p = .631). These results suggest that a protective self-presentation style may incline certain individuals to cooperate with hypnotic suggestions...
  29. pmc U-shaped relation between plasma oxytocin levels and behavior in the trust game
    Songfa Zhong
    Department of Economics, National University of Singapore, Singapore, Singapore
    PLoS ONE 7:e51095. 2012
    ..Our results contribute to a deeper understanding of the biological basis of human trust and underscore the usefulness of peripheral plasma OT measures in characterizing human social behavior...
  30. doi request reprint Heritability of children's prosocial behavior and differential susceptibility to parenting by variation in the dopamine receptor D4 gene
    Ariel Knafo
    Psychology Department, Hebrew University of Jerusalem, Mount Scopus, Jerusalem 91905, Israel
    Dev Psychopathol 23:53-67. 2011
    ....
  31. doi request reprint Identification of a functional rare variant in autism using genome-wide screen for monoallelic expression
    Eyal Ben-David
    Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Edmond J Safra Campus, Jerusalem 91904, Israel
    Hum Mol Genet 20:3632-41. 2011
    ....
  32. ncbi request reprint How anorexic-like are the symptom and personality profiles of aesthetic athletes?
    Rachel Bachner-Melman
    Department of Psychology, Hebrew University of Jerusalem, Israel
    Med Sci Sports Exerc 38:628-36. 2006
    ..We tested the hypothesis that aesthetic athletes (AA) have anorexic-like eating attitudes and behaviors, share personality characteristics such as perfectionism and obsessiveness, and are at high risk of eating disorders...
  33. doi request reprint Imaging genetics for utility of risks over gains and losses
    Songfa Zhong
    Department of Economics, National University of Singapore, Singapore
    Neuroimage 59:540-6. 2012
    ..Together, our results suggest the role of the amygdala and corresponding serotonergic pathway in evaluating losses. This further corroborates the hypothesis of serotonin being linked to dopamine in an "opponent partnership"...
  34. doi request reprint Vasopressin selectively impairs emotion recognition in men
    Florina Uzefovsky
    Psychology Department, Hebrew University, Jerusalem 91501, Israel
    Psychoneuroendocrinology 37:576-80. 2012
    ..The current report emphasizes the selective role of AVP in male emotional perception and empathy, a core element in all human social interactions...
  35. ncbi request reprint Acetylcholinesterase/paraoxonase interactions increase the risk of insecticide-induced Parkinson's disease
    Liat BenMoyal-Segal
    The Life Sciences Institute, The Hebrew University of Jerusalem, Israel
    FASEB J 19:452-4. 2005
    ..Our findings suggest that inherited interactive weakness of AChE and PON1 expression increases the insecticide-induced occurrence of Parkinson's disease...
  36. doi request reprint Hypnotizability and sensorimotor gating: a dopaminergic mechanism of hypnosis
    Raz Levin
    Department of Psychiatry, Herzog Memorial Hospital, Givat Shaul, Jerusalem, Israel
    Int J Clin Exp Hypn 59:399-405. 2011
    ....
  37. doi request reprint The Broad Autism Phenotype Questionnaire: mothers versus fathers of children with an autism spectrum disorder
    Ifat Seidman
    Department of Psychology, Hebrew University of Jerusalem, Mount Scopus, 91905 Jerusalem, Israel
    J Autism Dev Disord 42:837-46. 2012
    ..Results are discussed in reference to sex differences in BAP-related characteristics in parents of children with autism...
  38. ncbi request reprint Family-based and population study of a functional promoter-region monoamine oxidase A polymorphism in autism: possible association with IQ
    Nurit Yirmiya
    Department of Psychology, Hebrew University of Jerusalem, Jerusalem, Israel
    Am J Med Genet 114:284-7. 2002
    ..5, P = 0.046, N = 28) in the small group of autism subjects recruited from families with two affected siblings...
  39. doi request reprint Research review: crossing syndrome boundaries in the search for brain endophenotypes
    Yonata Levy
    Psychology Department, Hebrew University, Jerusalem, Israel
    J Child Psychol Psychiatry 50:657-68. 2009
    ..Cohort selection should rest on behavioral homogeneity, enabling, when necessary, syndrome heterogeneity...
  40. doi request reprint The sorting test of the D-KEFS in current and weight restored anorexia nervosa patients
    Eyal Heled
    Day Treatment Rehabilitation Unit, Sheba Medical Center, Ramat Gan, Israel Department of Psychology, Hebrew University, Jerusalem, Israel
    Int J Eat Disord 47:92-8. 2014
    ..The aim of this study is to further examine EF in women with past and present AN and to compare their performances in verbal and visual modalities with women who have never suffered from an eating disorder...
  41. ncbi request reprint High glycine levels are associated with prepulse inhibition deficits in chronic schizophrenia patients
    Uriel Heresco-Levy
    Psychiatry and Research Department, Ezrath Nashim Herzog Memorial Hospital, P O Box 3900, Givat Shaul 91351, Jerusalem, Israel
    Schizophr Res 91:14-21. 2007
    ..4, p=0.03). These preliminary findings indirectly support previous observations on ketamine effects upon PPI in humans and suggest a dissociation of symptomatology and PPI changes as function of NMDAR modulation in schizophrenia...
  42. ncbi request reprint An update on molecular genetic studies of human personality traits
    Richard P Ebstein
    S Herzog Memorial Hospital and Psychology Department, Scheinfeld Center, Hebrew University, Jerusalem, Israel
    Appl Bioinformatics 1:57-68. 2002
    ....