Lindon J Eaves

Summary

Publications

  1. doi request reprint Putting the 'human' back in genetics: modeling the extended kinships of twins
    Lindon Eaves
    Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America
    Twin Res Hum Genet 12:1-7. 2009
  2. doi request reprint Developmental-genetic effects on level and change in childhood fears of twins during adolescence
    Lindon J Eaves
    Virginia Institute for Psychiatric and Behavioral Genetics, Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA 23298 0003, USA
    J Child Psychol Psychiatry 49:1201-10. 2008
  3. pmc Flexible Mx specification of various extended twin kinship designs
    Hermine H Maes
    Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia 23298 0003, United States of America
    Twin Res Hum Genet 12:26-34. 2009
  4. ncbi request reprint Genetic and cultural transmission of antisocial behavior: an extended twin parent model
    Hermine H Maes
    Department of Human Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia 23298 0003, USA
    Twin Res Hum Genet 10:136-50. 2007
  5. pmc The impact of environmental experiences on symptoms of anxiety and depression across the life span
    Kenneth S Kendler
    Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298, USA
    Psychol Sci 22:1343-52. 2011
  6. doi request reprint The mediating effect of parental neglect on adolescent and young adult anti-sociality: a longitudinal study of twins and their parents
    Lindon J Eaves
    Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, VA 23298, USA
    Behav Genet 40:425-37. 2010
  7. pmc Fetal and maternal genes' influence on gestational age in a quantitative genetic analysis of 244,000 Swedish births
    Timothy P York
    Department of Human and Molecular Genetics, School of Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA
    Am J Epidemiol 178:543-50. 2013
  8. ncbi request reprint A twin study of genetic and environmental influences on tobacco initiation, regular tobacco use and nicotine dependence
    Hermine H Maes
    Departments of Human Genetics and Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298 0003, USA
    Psychol Med 34:1251-61. 2004
  9. pmc A longitudinal twin study of fears from middle childhood to early adulthood: evidence for a developmentally dynamic genome
    Kenneth S Kendler
    Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University Medical School, Box 980126, 800 E Leigh St, Room 1 123, Richmond, VA 23298 0126, USA
    Arch Gen Psychiatry 65:421-9. 2008
  10. pmc Genetic and environmental transmission of body mass index fluctuation
    Jocilyn E Bergin
    Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, MCV, P O Box 980126, Richmond, VA 23298, USA
    Behav Genet 42:867-74. 2012

Detail Information

Publications34

  1. doi request reprint Putting the 'human' back in genetics: modeling the extended kinships of twins
    Lindon Eaves
    Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America
    Twin Res Hum Genet 12:1-7. 2009
    ....
  2. doi request reprint Developmental-genetic effects on level and change in childhood fears of twins during adolescence
    Lindon J Eaves
    Virginia Institute for Psychiatric and Behavioral Genetics, Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA 23298 0003, USA
    J Child Psychol Psychiatry 49:1201-10. 2008
    ....
  3. pmc Flexible Mx specification of various extended twin kinship designs
    Hermine H Maes
    Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia 23298 0003, United States of America
    Twin Res Hum Genet 12:26-34. 2009
    ..Results indicate that biases in the estimation of variance components depend both on the types of relative available for analysis, and on the underlying genetic and environmental architecture of the phenotype of interest...
  4. ncbi request reprint Genetic and cultural transmission of antisocial behavior: an extended twin parent model
    Hermine H Maes
    Department of Human Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia 23298 0003, USA
    Twin Res Hum Genet 10:136-50. 2007
    ..This study showed significant heritability, which is slightly increased by assortative mating, and significant effects of primarily nonparental shared environment on CD...
  5. pmc The impact of environmental experiences on symptoms of anxiety and depression across the life span
    Kenneth S Kendler
    Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298, USA
    Psychol Sci 22:1343-52. 2011
    ..By middle adulthood, environmental experiences contributed substantially to stable and predictable interindividual differences in levels of anxiety and depression...
  6. doi request reprint The mediating effect of parental neglect on adolescent and young adult anti-sociality: a longitudinal study of twins and their parents
    Lindon J Eaves
    Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, VA 23298, USA
    Behav Genet 40:425-37. 2010
    ..The longitudinal study of twins and their parents makes it possible to demonstrate there is a direct causal effect of childhood adversity on child conduct disorder over and above any indirect genetic correlation...
  7. pmc Fetal and maternal genes' influence on gestational age in a quantitative genetic analysis of 244,000 Swedish births
    Timothy P York
    Department of Human and Molecular Genetics, School of Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA
    Am J Epidemiol 178:543-50. 2013
    ..Since environmental factors explained most differences in the timing of birth, genetic studies may benefit from understanding the specific effect of fetal and maternal genes in the context of these yet-unidentified factors. ..
  8. ncbi request reprint A twin study of genetic and environmental influences on tobacco initiation, regular tobacco use and nicotine dependence
    Hermine H Maes
    Departments of Human Genetics and Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298 0003, USA
    Psychol Med 34:1251-61. 2004
    ..As the development of ND requires regular tobacco use (RTU) which in turn requires TI, a conditional approach is necessary...
  9. pmc A longitudinal twin study of fears from middle childhood to early adulthood: evidence for a developmentally dynamic genome
    Kenneth S Kendler
    Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University Medical School, Box 980126, 800 E Leigh St, Room 1 123, Richmond, VA 23298 0126, USA
    Arch Gen Psychiatry 65:421-9. 2008
    ..While the nature of common fears changes over development, we do not know whether genetic effects on fear-proneness are developmentally stable or developmentally dynamic...
  10. pmc Genetic and environmental transmission of body mass index fluctuation
    Jocilyn E Bergin
    Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, MCV, P O Box 980126, Richmond, VA 23298, USA
    Behav Genet 42:867-74. 2012
    ....
  11. pmc Unraveling the effect of genes and environment in the transmission of parental antisocial behavior to children's conduct disturbance, depression and hyperactivity
    Judy L Silberg
    Department of Human and Molecular Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298 0003, USA
    J Child Psychol Psychiatry 53:668-77. 2012
    ....
  12. ncbi request reprint Genetic and cultural transmission of smoking initiation: an extended twin kinship model
    Hermine H Maes
    Department of Human Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, 980003, 23298 0003, Richmond, VA 23298 0003, USA
    Behav Genet 36:795-808. 2006
    ....
  13. ncbi request reprint Childhood adversity, monoamine oxidase a genotype, and risk for conduct disorder
    Debra L Foley
    Department of Human Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virgoinia Commonwaelth University, Richmond, 23298 0003, USA
    Arch Gen Psychiatry 61:738-44. 2004
    ..Very little is known about how different sets of risk factors interact to influence risk for psychiatric disorder...
  14. ncbi request reprint Genotype x Environment interaction in psychopathology: fact or artifact?
    Lindon J Eaves
    Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, Virginia 23298, USA
    Twin Res Hum Genet 9:1-8. 2006
    ..There is therefore reason to question the biological significance of published findings...
  15. pmc Racial differences in genetic and environmental risk to preterm birth
    Timothy P York
    Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America
    PLoS ONE 5:e12391. 2010
    ..This study provides a comprehensive description of the relative genetic and environmental contributions to racial differences in gestational age...
  16. ncbi request reprint Familial influences on alcohol use in adolescent female twins: testing for genetic and environmental interactions
    Donna R Miles
    Department of Human Genetics, Virginia Commonwealth University, Virginia Institute for Psychiatric and Behavioral Genetics, P O Box 980003, 800 East Leigh St, Biotech One, Suite 100, Richmond, Virginia, 23298 0003, USA
    J Stud Alcohol 66:445-51. 2005
    ..The present study examined whether measures of family adaptability and cohesion may moderate the genetic influence on risk for alcohol use among female adolescents...
  17. ncbi request reprint Epistatic and environmental control of genome-wide gene expression
    Timothy P York
    Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia 23298 0003, USA
    Twin Res Hum Genet 8:5-15. 2005
    ....
  18. ncbi request reprint Genetic and environmental influences on temperament in the first year of life: the Puerto Rico Infant Twin Study (PRINTS)
    Judy L Silberg
    Virginia Institute for Psychiatric and Behavioral Genetics, Department of Human Genetics, Virginia Commonwealth University, Richmond, Virginia, USA
    Twin Res Hum Genet 8:328-36. 2005
    ..In contrast, a significant effect of the shared environment on the temperamental trait of unadaptability has not been reported previously...
  19. ncbi request reprint Course and short-term outcomes of separation anxiety disorder in a community sample of twins
    Debra L Foley
    Human Genetics Department, Virginia Commonwealth University, Richmond 23298 0003, USA
    J Am Acad Child Adolesc Psychiatry 43:1107-14. 2004
    ..To assess the course and short-term outcomes associated with separation anxiety disorder (SAD) in a community setting...
  20. ncbi request reprint Revisiting the children of twins: can they be used to resolve the environmental effects of dyadic parental treatment on child behavior?
    Lindon J Eaves
    Virginia Institute of Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, Virginia 23298, USA
    Twin Res Hum Genet 8:283-90. 2005
    ..The fact that many candidate environments, such as parental divorce, are dyadic gives reason to question the interpretation of their correlations with behavior in the children of twins...
  21. doi request reprint Childhood separation anxiety disorder and adult onset panic attacks share a common genetic diathesis
    Roxann Roberson-Nay
    Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia 23298, USA
    Depress Anxiety 29:320-7. 2012
    ....
  22. doi request reprint Transmission of attitudes toward abortion and gay rights: effects of genes, social learning and mate selection
    Lindon J Eaves
    Departments of Human Genetics and Psychiatry, Virginia Commonwealth University, Richmond, VA, USA
    Behav Genet 38:247-56. 2008
    ..By contrast, the choice of mate is a social action that has a marked impact on the polarization of social attitudes and on the long-term influence that parents exert upon the next generation...
  23. ncbi request reprint Maternal smoking during pregnancy and risk to boys' conduct disturbance: an examination of the causal hypothesis
    Judy L Silberg
    Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia 23298 0003, USA
    Biol Psychiatry 53:130-5. 2003
    ..We undertook this study to determine whether the widely replicated link between maternal smoking and conduct disturbance (Cd) is better explained by a model of direct causation or of mother-offspring transmission of a latent Cd variable...
  24. ncbi request reprint Parent-child feedback predicts sibling contrast: using twin studies to test theories of parent-offspring interaction in infant behavior
    Lindon J Eaves
    Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia 23298, USA
    Twin Res Hum Genet 8:1-4. 2005
    ....
  25. pmc Increased frequency of micronuclei in adults with a history of childhood sexual abuse: a discordant monozygotic twin study
    Timothy P York
    Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America
    PLoS ONE 8:e55337. 2013
    ....
  26. pmc Genetic and environmental effects on diurnal dehydroepiandrosterone sulfate concentrations in middle-aged men
    Elizabeth C Prom-Wormley
    Virginia Institute for Behavioral and Psychiatric Genetics, Virginia Commonwealth University, Richmond, VA 23298 0126, United States
    Psychoneuroendocrinology 36:1441-52. 2011
    ..The characterization of the genetic and environmental contributions to daily DHEAS concentrations is thus important for understanding the genetics of health and aging...
  27. ncbi request reprint Multivariate adaptive regression splines: a powerful method for detecting disease-risk relationship differences among subgroups
    Timothy P York
    Massey Cancer Center, Virginia Commonwealth University, Virginia Institute for Psychiatric and Behavioral Genetics, P O Box 980003, Richmond, VA 23298 0003, USA
    Stat Med 25:1355-67. 2006
    ..It was shown that power was higher even if the regression curve was linear, that gains increased with the complexity of the curve, and that for highly non-linear curves model-free methods such as MARS might be the only alternative...
  28. ncbi request reprint Risks for conduct disorder symptoms associated with parental alcoholism in stepfather families versus intact families from a community sample
    Debra L Foley
    Department of Human Genetics, Virginia Commonwealth University, Richmond, VA 23298, USA
    J Child Psychol Psychiatry 45:687-96. 2004
    ....
  29. pmc Genetic and environmental influences on the transmission of parental depression to children's depression and conduct disturbance: an extended Children of Twins study
    Judy L Silberg
    Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA, USA
    J Child Psychol Psychiatry 51:734-44. 2010
    ....
  30. pmc Epistasis between COMT and MTHFR in maternal-fetal dyads increases risk for preeclampsia
    Lori D Hill
    Department of Obstetrics and Gynecology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America
    PLoS ONE 6:e16681. 2011
    ..341 and P = 0.219, respectively). Our findings demonstrate a role for both maternal and fetal COMT in preeclampsia and highlight the importance of including allelic variation in MTHFR...
  31. ncbi request reprint Modulation of gene expression by genetic and environmental heterogeneity in timing of a developmental milestone
    Lindon J Eaves
    Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, Virginia 23298 0003, USA
    Behav Genet 33:1-6. 2003
    ..The impact of these effects on age patterns in twin correlations is examined and their relevance to current data on developmental change discussed briefly...
  32. pmc Estimating fetal and maternal genetic contributions to premature birth from multiparous pregnancy histories of twins using MCMC and maximum-likelihood approaches
    Timothy P York
    Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, Virginia 32398 0003, United States of America
    Twin Res Hum Genet 12:333-42. 2009
    ..We anticipate the flexibility of MCMC methods to handle increasingly complex models to be of particular relevance for the study of birth outcomes...
  33. ncbi request reprint Assessment of the within-family environment in twins: absolute versus differential ratings, and relationship with conduct problems
    Rene Carbonneau
    Virginia Institute for Psychiatric and Behavioral Genetics, USA
    J Child Psychol Psychiatry 43:1064-74. 2002
    ..The aim was to compare the psychometric properties of absolute versus differential ratings of the within-family environments and to examine their associations with conduct problems in 8-16-year-old twins...
  34. ncbi request reprint cDNA microarray analysis identifies genes induced in common by peptide growth factors and androgen in human prostate epithelial cells
    Timothy P York
    Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia 23298, USA
    Mol Carcinog 44:242-51. 2005
    ..These results provide comprehensive and unique insights into potential mechanisms by which peptide growth factors provide alternate pathways to control prostate epithelial cell proliferation in malignant states...