Tathagata Dutta

Summary

Publications

  1. ncbi request reprint Intracellular macrophage uptake of rifampicin loaded mannosylated dendrimers
    Palanirajan Vijayaraj Kumar
    Pharmaceutics Research Laboratory, Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar 470 003, India
    J Drug Target 14:546-56. 2006
  2. ncbi request reprint Functional polymeric nanoparticles: an efficient and promising tool for active delivery of bioactives
    Manoj Nahar
    Pharmaceutics Research Laboratory, Department of Pharmaceutical Sciences, Dr H S Gour University, Sagar M P, 470003, India
    Crit Rev Ther Drug Carrier Syst 23:259-318. 2006
  3. ncbi request reprint Dermal and transdermal delivery of an anti-psoriatic agent via ethanolic liposomes
    Vaibhav Dubey
    Pharmaceutics Research Laboratory, Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar M P, 470003, India
    J Control Release 123:148-54. 2007
  4. ncbi request reprint Targeting of efavirenz loaded tuftsin conjugated poly(propyleneimine) dendrimers to HIV infected macrophages in vitro
    Tathagata Dutta
    Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar, M P 470003, India
    Eur J Pharm Sci 34:181-9. 2008
  5. ncbi request reprint Poly (propyleneimine) dendrimer based nanocontainers for targeting of efavirenz to human monocytes/macrophages in vitro
    Tathagata Dutta
    Department of Pharmaceutical Sciences, Dr H S Gour University, Sagar, MP 470 003, India
    J Drug Target 15:89-98. 2007
  6. ncbi request reprint Targeting potential and anti-HIV activity of lamivudine loaded mannosylated poly (propyleneimine) dendrimer
    Tathagata Dutta
    Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar M P 470 003, India
    Biochim Biophys Acta 1770:681-6. 2007
  7. ncbi request reprint Radiolabeling, pharmacoscintigraphic evaluation and antiretroviral efficacy of stavudine loaded 99mTc labeled galactosylated liposomes
    Minakshi Garg
    Pharmaceutics Research Laboratory, Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar 470003, MP, India
    Eur J Pharm Sci 33:271-81. 2008
  8. doi request reprint Exploring dendrimer towards dual drug delivery: pH responsive simultaneous drug-release kinetics
    Rakesh Kumar Tekade
    Pharmaceutics Research Laboratory, Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar, India
    J Microencapsul 26:287-96. 2009
  9. ncbi request reprint PEGylated dendritic architecture for development of a prolonged drug delivery system for an antitubercular drug
    P Vijayaraj Kumar
    Pharmaceutics Research Laboratory, Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar 470 003, India
    Curr Drug Deliv 4:11-9. 2007
  10. ncbi request reprint Investigations on the toxicological profile of functionalized fifth-generation poly (propylene imine) dendrimer
    Hrushikesh B Agashe
    Pharmaceutics Research Laboratory, Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar, India
    J Pharm Pharmacol 58:1491-8. 2006

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Intracellular macrophage uptake of rifampicin loaded mannosylated dendrimers
    Palanirajan Vijayaraj Kumar
    Pharmaceutics Research Laboratory, Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar 470 003, India
    J Drug Target 14:546-56. 2006
    ..0 and AM uptake was observed. The present novel dendritic system displayed suitability in terms of biocompatibility and site-specific delivery of antitubercular drug RIF...
  2. ncbi request reprint Functional polymeric nanoparticles: an efficient and promising tool for active delivery of bioactives
    Manoj Nahar
    Pharmaceutics Research Laboratory, Department of Pharmaceutical Sciences, Dr H S Gour University, Sagar M P, 470003, India
    Crit Rev Ther Drug Carrier Syst 23:259-318. 2006
    ..This review also addresses formidable challenges encountered, and proposes some future strategies for development of a promising site-specific active delivery system...
  3. ncbi request reprint Dermal and transdermal delivery of an anti-psoriatic agent via ethanolic liposomes
    Vaibhav Dubey
    Pharmaceutics Research Laboratory, Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar M P, 470003, India
    J Control Release 123:148-54. 2007
    ..Our results suggests that ethosomes are an efficient carrier for dermal and transdermal delivery of MTX...
  4. ncbi request reprint Targeting of efavirenz loaded tuftsin conjugated poly(propyleneimine) dendrimers to HIV infected macrophages in vitro
    Tathagata Dutta
    Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar, M P 470003, India
    Eur J Pharm Sci 34:181-9. 2008
    ..TuPPI was found to reduce the viral load by 99% at a concentration of 0.625 ng/ml, which is due to the enhanced cellular uptake, reduced toxicity and the inherent anti-HIV activity of TuPPI...
  5. ncbi request reprint Poly (propyleneimine) dendrimer based nanocontainers for targeting of efavirenz to human monocytes/macrophages in vitro
    Tathagata Dutta
    Department of Pharmaceutical Sciences, Dr H S Gour University, Sagar, MP 470 003, India
    J Drug Target 15:89-98. 2007
    ..Results suggest that the proposed carriers hold potential to increase the efficacy and reduce the toxicity of antiretroviral therapy...
  6. ncbi request reprint Targeting potential and anti-HIV activity of lamivudine loaded mannosylated poly (propyleneimine) dendrimer
    Tathagata Dutta
    Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar M P 470 003, India
    Biochim Biophys Acta 1770:681-6. 2007
    ....
  7. ncbi request reprint Radiolabeling, pharmacoscintigraphic evaluation and antiretroviral efficacy of stavudine loaded 99mTc labeled galactosylated liposomes
    Minakshi Garg
    Pharmaceutics Research Laboratory, Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar 470003, MP, India
    Eur J Pharm Sci 33:271-81. 2008
    ..Reduced uptake of the galactosylated liposomes in bone and higher and prolonged accumulation in mononuclear phagocyte system (MPS)-rich organs indicates the excellent potential of this formulation in the treatment of HIV infection...
  8. doi request reprint Exploring dendrimer towards dual drug delivery: pH responsive simultaneous drug-release kinetics
    Rakesh Kumar Tekade
    Pharmaceutics Research Laboratory, Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar, India
    J Microencapsul 26:287-96. 2009
    ..A cytotoxicity study was performed on HeLa cell lines by MTT assay, wherein after 72 h, the dual-drug loaded dendrimer was found to be more efficient (IC(50) 0.5 µM) as compared to that of the free drug combination (IC(50) 0.75 µM)...
  9. ncbi request reprint PEGylated dendritic architecture for development of a prolonged drug delivery system for an antitubercular drug
    P Vijayaraj Kumar
    Pharmaceutics Research Laboratory, Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar 470 003, India
    Curr Drug Deliv 4:11-9. 2007
    ..The PEGylation of the systems was found to have increased their drug-loading capacity, reduced their drug release rate and hemolytic toxicity. The systems were found suitable for prolonged delivery of rifampicin...
  10. ncbi request reprint Investigations on the toxicological profile of functionalized fifth-generation poly (propylene imine) dendrimer
    Hrushikesh B Agashe
    Pharmaceutics Research Laboratory, Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar, India
    J Pharm Pharmacol 58:1491-8. 2006
    ..Functionalization greatly improved the toxicity profile of the parent dendrimer. Hence it is proposed that these functionalized forms of PPI dendrimer have great potential as bio-compatible drug vehicles...
  11. ncbi request reprint Stability study of stavudine-loaded O-palmitoyl-anchored carbohydrate-coated liposomes
    Minakshi Garg
    Pharmaceutics Research Laboratory, Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar, MP, India
    AAPS PharmSciTech 8:Article 38. 2007
    ..Carbohydrate coating of the liposomes could enhance the stability of liposomes at 25 degrees C +/- 2 degrees C/60% +/- 5% RH and 40 degrees C +/- 2 degrees C/75% +/- 5% RH...
  12. ncbi request reprint Investigations on biodistribution of technetium-99m-labeled carbohydrate-coated poly(propylene imine) dendrimers
    Hrushikesh B Agashe
    Pharmaceutis Research Laboratory, Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar, India
    Nanomedicine 3:120-7. 2007
    ..This information could serve as a useful platform in designing carbohydrate-coated dendrimers for selective delivery of bioactive agents to liver...
  13. ncbi request reprint Poly(propyleneimine) dendrimer and dendrosome mediated genetic immunization against hepatitis B
    Tathagata Dutta
    Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar 470003, MP, India
    Vaccine 26:3389-94. 2008
    ..Higher level of IFN-gamma suggests that the immune response was strictly Th1 mediated. Our observations clearly prove the superiority of dendrosomes over PPI-DNA complex and pDNA for genetic immunization against hepatitis B...
  14. ncbi request reprint Reduced hepatic toxicity, enhanced cellular uptake and altered pharmacokinetics of stavudine loaded galactosylated liposomes
    Minakshi Garg
    Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar, India
    Eur J Pharm Biopharm 67:76-85. 2007
    ..07+/-1.25h). This formulation did not show either hematological or hepatic toxicity. Galactosylation of liposomes alter the biodistribution of encapsulated drug thereby delivering the drug to cells bearing galactose specific receptors...
  15. ncbi request reprint Surface-engineered dendrimers for dual drug delivery: a receptor up-regulation and enhanced cancer targeting strategy
    Rakesh Kumar Tekade
    Pharmaceutics Research Laboratory, Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar, India
    J Drug Target 16:758-72. 2008
    ....