The virtual colonoscopy study: a large multicenter clinical trial designed to compare two diagnostic screening proceduresValerie L Durkalski
TCIG STATS, The Clinical Innovation Group, MUSC Foundation for Research and Development, The Medical University of South Carolina, Charleston, SC, USA
Control Clin Trials 23:570-83. 2002
..Strategies for the design and implementation of the study are shared as well as the challenges encountered...
Analysis of clustered matched-pair dataValerie L Durkalski
The Clinical Innovation Group TCIG, Medical University of South Carolina, Foundation for Research Development, Charleston, SC 29401, USA
Stat Med 22:2417-28. 2003
..Using Monte Carlo simulation, the size and power of the proposed test are compared to those of two currently available methods. To illustrate practical application, clustered matched-pair data from two clinical studies are analysed...
Analysis of clustered matched-pair data for a non-inferiority study designValerie L Durkalski
TCIG STATS, The Clinical Innovation Group, MUSC Foundation for Research Development, Charleston, SC, USA
Stat Med 22:279-90. 2003
..This paper proposes a Wald-type test statistic for a non-inferiority hypothesis and applies it to the comparison of two diagnostic procedures...
Rationale and design: telephone-delivered behavioral skills interventions for Blacks with Type 2 diabetesLeonard E Egede
Center for Disease Prevention and Health Interventions for Diverse Populations, Ralph H, Johnson VAMC, Charleston, SC, USA
Trials 11:35. 2010
..This study provides a unique opportunity to address this gap in the literature...
Computed tomographic colonography (virtual colonoscopy): a multicenter comparison with standard colonoscopy for detection of colorectal neoplasiaPeter B Cotton
Department of Gastroenterology, The Digestive Disease Center, Medical University of South Carolina, Charleston 29425, USA
JAMA 291:1713-9. 2004
..Computed tomographic colonography (CTC), also known as virtual colonoscopy, has been reported to be reasonably accurate in the diagnosis of colorectal neoplasia in studies performed at expert centers...
Analysis of trichotomous pharmaceutical endpointsVance W Berger
Biometry Research Group, National Cancer Institute, University of Maryland, Baltimore County, Maryland, USA
J Biopharm Stat 15:739-45. 2005
..The purpose of this paper is to fill this gap by offering an objective approach for parameter selection, and to provide real data examples to illustrate the use of this objective approach...