Nicolas Dupre

Summary

Publications

  1. doi request reprint [Hereditary ataxias, spastic parapareses and neuropathies in Eastern Canada]
    N Dupre
    Département des Sciences Neurologiques, faculté de médecine de l université Laval, hôpital Enfant Jésus, CHAU de Québec, 1401, 18e rue, G1J 1Z4 Québec, Canada
    Rev Neurol (Paris) 164:12-21. 2008
  2. doi request reprint Clinical, electrophysiologic, and genetic study of non-dystrophic myotonia in French-Canadians
    Nicolas Dupre
    Department of Neurological Sciences, CHAUQ Enfant Jésus, Faculty of Medicine, Laval University, Quebec City, QC, Canada
    Neuromuscul Disord 19:330-4. 2009
  3. ncbi request reprint LRRK2 is not a significant cause of Parkinson's disease in French-Canadians
    Nicolas Dupre
    Faculty of Medicine, Laval University, Department of Neurological Sciences, CHAUQ Enfant Jésus, Quebec City, Quebec, Canada
    Can J Neurol Sci 34:333-5. 2007
  4. ncbi request reprint Hereditary ataxia, spastic paraparesis and neuropathy in the French-Canadian population
    Nicolas Dupre
    Department of Neurological Sciences, CHAUQ Enfant Jésus, Quebec City, QC, Canada
    Can J Neurol Sci 33:149-57. 2006
  5. ncbi request reprint A case of familial Creutzfeldt-Jakob disease presenting with dry cough
    Sandrine Larue
    Department of Neurological Sciences, CHAUQ Enfant Jésus, Laval University, Quebec City, QC, Canada
    Can J Neurol Sci 33:243-5. 2006
  6. doi request reprint Clinical validity of the Mattis Dementia Rating Scale-2 in Parkinson disease with MCI and dementia
    Evelyne Matteau
    Ecole de Psychologie, Université Laval and Centre de recherche Université Laval Robert Giffard, Quebec City, QC, Canada
    J Geriatr Psychiatry Neurol 25:100-6. 2012
  7. ncbi request reprint Myotonia congenita--a cause of muscle weakness and stiffness
    Nicolas Chrestian
    University of Laval, QC, Canada
    Nat Clin Pract Neurol 2:393-9; quiz following 399. 2006
  8. ncbi request reprint A novel mutation in a large French-Canadian family with LGMD1B
    Nicolas Chrestian
    Faculty of Medicine, Laval University, Quebec City, Canada
    Can J Neurol Sci 35:331-4. 2008
  9. ncbi request reprint Clinical and genetic study of autosomal recessive cerebellar ataxia type 1
    Nicolas Dupre
    Faculty of Medicine, Laval University, Department of Neurological Sciences, Centre Hospitalier Affilié Universitaire de Québec Enfant Jésus, 18th Street, Quebec City, Quebec, Canada
    Ann Neurol 62:93-8. 2007
  10. doi request reprint Cognitive impairment in ARCA-1, a newly discovered pure cerebellar ataxia syndrome
    Robert Laforce
    Département des Sciences Neurologiques Centre Hospitalier Affilié Enfant Jésus, Universite Laval, 1401, 18ième rue, Laval, QC, Canada G1J 1Z4
    Cerebellum 9:443-53. 2010

Collaborators

Detail Information

Publications19

  1. doi request reprint [Hereditary ataxias, spastic parapareses and neuropathies in Eastern Canada]
    N Dupre
    Département des Sciences Neurologiques, faculté de médecine de l université Laval, hôpital Enfant Jésus, CHAU de Québec, 1401, 18e rue, G1J 1Z4 Québec, Canada
    Rev Neurol (Paris) 164:12-21. 2008
    ..We have summarized our current knowledge of the various hereditary ataxias, spastic parapareses and neuropathies in Eastern Canada. The study of the more common and homogenous features of these diseases has been largely completed...
  2. doi request reprint Clinical, electrophysiologic, and genetic study of non-dystrophic myotonia in French-Canadians
    Nicolas Dupre
    Department of Neurological Sciences, CHAUQ Enfant Jésus, Faculty of Medicine, Laval University, Quebec City, QC, Canada
    Neuromuscul Disord 19:330-4. 2009
    ..The French-Canadian population shows wide phenotypic and genotypic heterogeneity in non-dystrophic myotonias...
  3. ncbi request reprint LRRK2 is not a significant cause of Parkinson's disease in French-Canadians
    Nicolas Dupre
    Faculty of Medicine, Laval University, Department of Neurological Sciences, CHAUQ Enfant Jésus, Quebec City, Quebec, Canada
    Can J Neurol Sci 34:333-5. 2007
    ..Objective: Demonstrate if mutations in the LRRK2 gene are a significant cause of Parkinson's disease (PD) in the French-Canadian founder population...
  4. ncbi request reprint Hereditary ataxia, spastic paraparesis and neuropathy in the French-Canadian population
    Nicolas Dupre
    Department of Neurological Sciences, CHAUQ Enfant Jésus, Quebec City, QC, Canada
    Can J Neurol Sci 33:149-57. 2006
    ..We predict that the regional populations of Canada will allow the identification of new rare forms of hereditary ataxias, spastic parapareses and neuropathies, and contribute to the unravelling of the genetic basis of these entities...
  5. ncbi request reprint A case of familial Creutzfeldt-Jakob disease presenting with dry cough
    Sandrine Larue
    Department of Neurological Sciences, CHAUQ Enfant Jésus, Laval University, Quebec City, QC, Canada
    Can J Neurol Sci 33:243-5. 2006
    ..The 200k mutation within the gene encoding PrP, located on the short arm of chromosome 20, accounts for more than 70% of families with CJD worldwide...
  6. doi request reprint Clinical validity of the Mattis Dementia Rating Scale-2 in Parkinson disease with MCI and dementia
    Evelyne Matteau
    Ecole de Psychologie, Université Laval and Centre de recherche Université Laval Robert Giffard, Quebec City, QC, Canada
    J Geriatr Psychiatry Neurol 25:100-6. 2012
    ..These findings suggest that MDRS-2 is a useful tool to identify dementia but that there might be a ceiling effect in the MDRS-2 cutoff score to diagnose MCI in PD...
  7. ncbi request reprint Myotonia congenita--a cause of muscle weakness and stiffness
    Nicolas Chrestian
    University of Laval, QC, Canada
    Nat Clin Pract Neurol 2:393-9; quiz following 399. 2006
    ..A previous needle electromyogram had confirmed the presence of myotonia, but a muscle biopsy had revealed no evidence of dystrophy...
  8. ncbi request reprint A novel mutation in a large French-Canadian family with LGMD1B
    Nicolas Chrestian
    Faculty of Medicine, Laval University, Quebec City, Canada
    Can J Neurol Sci 35:331-4. 2008
    ....
  9. ncbi request reprint Clinical and genetic study of autosomal recessive cerebellar ataxia type 1
    Nicolas Dupre
    Faculty of Medicine, Laval University, Department of Neurological Sciences, Centre Hospitalier Affilié Universitaire de Québec Enfant Jésus, 18th Street, Quebec City, Quebec, Canada
    Ann Neurol 62:93-8. 2007
    ..Define the phenotype and genotype of a cluster of families with a relatively pure cerebellar ataxia referred to as autosomal recessive cerebellar ataxia type 1 (ARCA-1)...
  10. doi request reprint Cognitive impairment in ARCA-1, a newly discovered pure cerebellar ataxia syndrome
    Robert Laforce
    Département des Sciences Neurologiques Centre Hospitalier Affilié Enfant Jésus, Universite Laval, 1401, 18ième rue, Laval, QC, Canada G1J 1Z4
    Cerebellum 9:443-53. 2010
    ..These deficits are correlated with an overall moderate impact on patient's autonomy. Our data favour an indirect participation of the dorsolateral prefrontal and posterior parietal cortical areas to the cerebrocerebellar circuit...
  11. ncbi request reprint SPG4 founder effect in French Canadians with hereditary spastic paraplegia
    Inge A Meijer
    Center for the Study of Brain Diseases, CHUM Research Center, Notre Dame Hospital, Montreal, QC, Canada
    Can J Neurol Sci 34:211-4. 2007
    ..The aim of this study is to estimate the frequency of the c.G1801A mutation in the French Canadian (FC) population and to determine whether this mutation originates from a common ancestor...
  12. ncbi request reprint Autosomal dominant primary lateral sclerosis
    Nicolas Dupre
    Center for the Study of Brain Diseases, Universite de Montreal CHUM Research Center, Notre Dame Hospital, Montreal, QC, Canada
    Neurology 68:1156-7. 2007
  13. pmc Biophysical characterization of M1476I, a sodium channel founder mutation associated with cold-induced myotonia in French Canadians
    Juan Zhao
    Le Centre de recherche en neurosciences, Institut universitaire en santé mentale de Québec, 2601 Chemin de Canardière, Quebec, QC, G1J 2G3, Canada
    J Physiol 590:2629-44. 2012
    ..Increased extracellular concentrations of potassium had no effect on either M1476I or WT currents. These results indicated that cooling can augment the disruption of the voltage dependence of fast inactivation by M1476I channels...
  14. doi request reprint Mattis Dementia Rating Scale 2: screening for MCI and dementia
    Evelyne Matteau
    Ecole de Psychologie, Université Laval and Centre de recherche Université Laval Robert Giffard, Quebec City, Quebec, Canada
    Am J Alzheimers Dis Other Demen 26:389-98. 2011
    ..No difference was found between the MCI groups. The MDRS-2 is a suitable short scale for MCI and dementia screening but is not specific enough to differentiate between A-MCI and PD-MCI...
  15. ncbi request reprint Adrenomyeloneuropathy: report of a new mutation in a French Canadian female
    Annie Dionne
    Départment des Sciences Neurologiques, CHAUQ Hôpital Enfant Jésus, McGill University, QC, Canada
    Can J Neurol Sci 32:261-3. 2005
    ..Female heterozygotes can be symptomatic, but they are frequently misdiagnosed as having multiple sclerosis...
  16. doi request reprint Analysis of the SORT1 gene in familial amyotrophic lateral sclerosis
    Veronique V Belzil
    Centre of Excellence in Neurosciences of Université de Montréal, CHUM Research Center, Montreal, QC H2L 4M1, Canada
    Neurobiol Aging 33:1845.e7-9. 2012
    ....
  17. doi request reprint Intra-arterial milrinone for reversible cerebral vasoconstriction syndrome
    Manon Bouchard
    Department of Neurological Sciences, CHA Enfant Jésus, Faculty of Medicine, Laval University, Quebec City, QC, Canada
    Headache 49:142-5. 2009
    ..Within hours of neurological deterioration, she was treated with intra-arterial milrinone, a phosphodiesterase inhibitor, which resulted in a rapid and sustained neurological improvement...
  18. doi request reprint A novel TYMP mutation in a French Canadian patient with mitochondrial neurogastrointestinal encephalomyopathy
    Robert Laforce
    Département des Sciences Neurologiques, Centre Hospitalier Affilie Universitaire De Quebec, Hopital de l Enfant Jesus, Quebec, Canada
    Clin Neurol Neurosurg 111:691-4. 2009
    ..We present herein the clinical, neuroimaging, neuromuscular, and molecular findings of the first French Canadian patient with MNGIE caused by a novel homozygous invariant splicing site (IVS5 +1 G>A) mutation of the TYMP gene...
  19. doi request reprint Increased obstacle clearance in people with ARCA-1 results in part from voluntary coordination changes between the thigh and shank segments
    Michael James Maclellan
    Center for Interdisciplinary Research in Rehabilitation and Social Integration, Quebec Rehabilitation Institute, Quebec, QC, Canada
    Cerebellum 10:732-44. 2011
    ..Further work is required to determine whether ataxia severity has an effect on the observed coordination variables...