Patricia K Duffner

Summary

Publications

  1. pmc The long term effects of chemotherapy on the central nervous system
    Patricia K Duffner
    Department of Neurology, Women and Children s Hospital of Buffalo, University of Buffalo School of Medicine, 219 Bryant St, Buffalo, NY 14222, USA
    J Biol 5:21. 2006
  2. doi request reprint Does galactocerebrosidase activity predict Krabbe phenotype?
    Kabir Jalal
    Department of Biostatistics, Population Health Observatory, School of Public Health and Health Professions, State University of New York at Buffalo, Buffalo, New York, USA
    Pediatr Neurol 47:324-9. 2012
  3. doi request reprint Later onset phenotypes of Krabbe disease: results of the world-wide registry
    Patricia K Duffner
    Hunter James Kelly Research Institute, Department of Neurology, School of Medicine, State University of New York at Buffalo, Buffalo, New York 14203, USA
    Pediatr Neurol 46:298-306. 2012
  4. doi request reprint Risk factors for cognitive decline in children treated for brain tumors
    Patricia K Duffner
    University at Buffalo School of Medicine, Hunter James Kelly Research Institute, Center of Excellence in Bioinformatics, 701 Ellicott Street, Buffalo, NY 14203, USA
    Eur J Paediatr Neurol 14:106-15. 2010
  5. doi request reprint Developmental and functional outcomes in children with a positive newborn screen for Krabbe disease: a pilot study of a phone-based interview surveillance technique
    Patricia K Duffner
    Department of Neurology, University at Buffalo School of Medicine, Buffalo, NY 14203, USA
    J Pediatr 161:258-63.e1. 2012
  6. doi request reprint Neurocognitive and neuroradiologic central nervous system late effects in children treated on Pediatric Oncology Group (POG) P9605 (standard risk) and P9201 (lesser risk) acute lymphoblastic leukemia protocols (ACCL0131): a methotrexate consequence? A rep
    Patricia K Duffner
    Department of Neurology, University at Buffalo School of Medicine Department of Pediatrics, Roswell Park Cancer Institute, Buffalo, NY Department of Pediatrics, University of Miami Miller School of Medicine and Holtz Children s Hospital, Miami, FL Statistics and Data Center, Children s Oncology Group, Monrovia, CA Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, TN Department of Pediatrics, Georgia Health Science Center, Augusta, GA Department of Pediatrics, West Virginia University Health Science Center, Charleston, WV
    J Pediatr Hematol Oncol 36:8-15. 2014
  7. doi request reprint Death rates in the U.S. due to Krabbe disease and related leukodystrophy and lysosomal storage diseases
    Amy L Barczykowski
    Population Health Observatory, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York, USA
    Am J Med Genet A 158:2835-42. 2012
  8. ncbi request reprint Early infantile Krabbe disease: results of the World-Wide Krabbe Registry
    Patricia K Duffner
    Hunter James Kelly Research Institute, Department of Neurology, School of Medicine, State University of New York at Buffalo, Buffalo, NY 14203, USA
    Pediatr Neurol 45:141-8. 2011
  9. ncbi request reprint Diagnosis of brain tumors in children
    Patricia K Duffner
    University at Buffalo School of Medicine, Hunter James Kelly Research Institute, Buffalo, NY, USA
    Expert Rev Neurother 7:875-85. 2007
  10. ncbi request reprint Long-term effects of radiation therapy on cognitive and endocrine function in children with leukemia and brain tumors
    Patricia K Duffner
    Department of Neurology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, 219 Bryant Street, Buffalo, NY 14222, USA
    Neurologist 10:293-310. 2004

Collaborators

Detail Information

Publications10

  1. pmc The long term effects of chemotherapy on the central nervous system
    Patricia K Duffner
    Department of Neurology, Women and Children s Hospital of Buffalo, University of Buffalo School of Medicine, 219 Bryant St, Buffalo, NY 14222, USA
    J Biol 5:21. 2006
    ..By identifying the cell populations at risk, these results may help explain the neurological problems previously seen after chemotherapy...
  2. doi request reprint Does galactocerebrosidase activity predict Krabbe phenotype?
    Kabir Jalal
    Department of Biostatistics, Population Health Observatory, School of Public Health and Health Professions, State University of New York at Buffalo, Buffalo, New York, USA
    Pediatr Neurol 47:324-9. 2012
    ..Our findings provide empiric evidence that the upper end (0.15 nmol/hour/mg protein) of the high-risk galactocerebrosidase group in the New York State newborn screening program is conservatively appropriate...
  3. doi request reprint Later onset phenotypes of Krabbe disease: results of the world-wide registry
    Patricia K Duffner
    Hunter James Kelly Research Institute, Department of Neurology, School of Medicine, State University of New York at Buffalo, Buffalo, New York 14203, USA
    Pediatr Neurol 46:298-306. 2012
    ..Five-year and 10-year survivals for all later onset phenotypes were at least 50%. The later onset Krabbe phenotypes differ from those with early infantile disease, but no specific predictor of phenotype was identified...
  4. doi request reprint Risk factors for cognitive decline in children treated for brain tumors
    Patricia K Duffner
    University at Buffalo School of Medicine, Hunter James Kelly Research Institute, Center of Excellence in Bioinformatics, 701 Ellicott Street, Buffalo, NY 14203, USA
    Eur J Paediatr Neurol 14:106-15. 2010
    ..Whether these changes in therapy will ultimately improve the quality of life of the long-term survivors is uncertain. Close follow-up of these children will be required throughout their lives...
  5. doi request reprint Developmental and functional outcomes in children with a positive newborn screen for Krabbe disease: a pilot study of a phone-based interview surveillance technique
    Patricia K Duffner
    Department of Neurology, University at Buffalo School of Medicine, Buffalo, NY 14203, USA
    J Pediatr 161:258-63.e1. 2012
    ....
  6. doi request reprint Neurocognitive and neuroradiologic central nervous system late effects in children treated on Pediatric Oncology Group (POG) P9605 (standard risk) and P9201 (lesser risk) acute lymphoblastic leukemia protocols (ACCL0131): a methotrexate consequence? A rep
    Patricia K Duffner
    Department of Neurology, University at Buffalo School of Medicine Department of Pediatrics, Roswell Park Cancer Institute, Buffalo, NY Department of Pediatrics, University of Miami Miller School of Medicine and Holtz Children s Hospital, Miami, FL Statistics and Data Center, Children s Oncology Group, Monrovia, CA Department of Radiological Sciences, St Jude Children s Research Hospital, Memphis, TN Department of Pediatrics, Georgia Health Science Center, Augusta, GA Department of Pediatrics, West Virginia University Health Science Center, Charleston, WV
    J Pediatr Hematol Oncol 36:8-15. 2014
    ..24%, 4/17 measures). This supports ongoing concerns about intensive MTX exposure as a major contributor to CNS late effects. ..
  7. doi request reprint Death rates in the U.S. due to Krabbe disease and related leukodystrophy and lysosomal storage diseases
    Amy L Barczykowski
    Population Health Observatory, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York, USA
    Am J Med Genet A 158:2835-42. 2012
    ..It is presumed that most, if not all, will develop later onset forms of the disease, but this is by no means certain...
  8. ncbi request reprint Early infantile Krabbe disease: results of the World-Wide Krabbe Registry
    Patricia K Duffner
    Hunter James Kelly Research Institute, Department of Neurology, School of Medicine, State University of New York at Buffalo, Buffalo, NY 14203, USA
    Pediatr Neurol 45:141-8. 2011
    ..Other biomarkers are needed to predict phenotype in the newborn screening population...
  9. ncbi request reprint Diagnosis of brain tumors in children
    Patricia K Duffner
    University at Buffalo School of Medicine, Hunter James Kelly Research Institute, Buffalo, NY, USA
    Expert Rev Neurother 7:875-85. 2007
    ..Diagnosis is then confirmed by neuroradiologic studies, including computed tomography, MRI and magnetic resonance spectroscopy...
  10. ncbi request reprint Long-term effects of radiation therapy on cognitive and endocrine function in children with leukemia and brain tumors
    Patricia K Duffner
    Department of Neurology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, 219 Bryant Street, Buffalo, NY 14222, USA
    Neurologist 10:293-310. 2004
    ..These complications have been studied most extensively in children with brain tumors and leukemia...