Isolation and antimalarial activity of peroxydisulfate oxidation products of primaquineVirendra K Dua
Malaria Research Centre, Field Station, Sector III, BHEL, Ranipur, Hardwar 249 403, India
Bioorg Med Chem Lett 12:3587-9. 2002
..One compound 6-methoxy-5,8 bis(4'-amino-1'-methylbutylamino)quinoline [P(1)] was found to have good gametocytocidal activity against Plasmodium yoelli infected mice at 10mg kg(-1) dose in vivo...
Chloroquine and desethylchloroquine concentrations in blood cells and plasma from Indian patients infected with sensitive or resistant Plasmodium falciparumV K Dua
Malaria Research Centre, Field Station, BHEL, Ranipur, Hardwar, India
Ann Trop Med Parasitol 94:565-70. 2000
..Similarly, the mean ratio between the blood-cell concentration of CQ on day 2 and the concurrent plasma concentration (BPr) was also relatively high in the sensitive group (P < 0.001)...
Plasmodium vivax relapses after 5 days of primaquine treatment, in some industrial complexes of IndiaV K Dua
Malaria Research Centre, Industrial Malaria Unit, BHEL, Sect III, Hardwar 249 403, India
Ann Trop Med Parasitol 95:655-9. 2001
..It may now be appropriate to implement the 14-day regimen recommended by the World Health Organization, although this is much less feasible under field conditions...
Multi-drug resistant Plasmodium falciparum malaria in Assam, India: timing of recurrence and anti-malarial drug concentrations in whole bloodVirendra K Dua
Malaria Research Centre, Field Station, Sector III, Ranipur, Hardwar, India
Am J Trop Med Hyg 69:555-7. 2003
..009 microg/ml (day 14), respectively. Therefore, monitoring of drug-resistant P. falciparum malaria and its proper treatment should be intensified to check the spread of multi-drug resistant strains in other parts of the country...
Liquid chromatographic determination of amodiaquine in human plasmaVirendra K Dua
Malaria Research Centre, Field Station, Sector III, BHEL, Hardwar 249403, India
J Chromatogr B Analyt Technol Biomed Life Sci 803:371-4. 2004
..48, 74.50 and 69.65%, respectively. Chloroquine and its metabolite desethyl chloroquine, quinine, sulfadoxine and primaquine do not interfere in the detection of amodiaquine, desethyl amodiaquine and bisdesethyl amodiaquine in plasma...
Anti-malarial activity of some xanthones isolated from the roots of Andrographis paniculataV K Dua
Malaria Research Centre, Sector III, BHEL, Hardwar 249 403, India
J Ethnopharmacol 95:247-51. 2004
..In vitro cytotoxicity against mammalian cells revealed that 1,2-dihydroxy-6,8-dimethoxy-xanthone is non-cytotoxic with its IC(50) > 32 microg ml(-1)...
High-performance liquid chromatographic assay for the determination of sulfadoxine and N-acetyl sulfadoxine in plasma from patients infected with sensitive and resistant Plasmodium falciparum malariaVirendra K Dua
National Institute of Malaria Research, Field Unit, Sector III, BHEL, Hardwar 249403, India
J Chromatogr B Analyt Technol Biomed Life Sci 860:160-5. 2007
..9% for non-responders which revealed that higher amounts of the metabolite N-acetyl sulfadoxine were present in non-responders. The method described should find an application in the therapeutic monitoring of malaria patients...
Antiprotozoal activities of traditional medicinal plants from the Garhwal region of North West Himalaya, IndiaVirendra K Dua
National Institute of Malaria Research, Field Unit, Hardwar 249403, India
J Ethnopharmacol 136:123-8. 2011
....
Larvivorous activity of Poecilia reticulata against Culex quinquefasciatus larvae in a polluted water drain in Hardwar, IndiaVirendra K Dua
National Institute of Malaria Research, Field Unit, Sector III, BHEL, Hardwar 249 403, India
J Am Mosq Control Assoc 23:481-3. 2007
..quinquefasciatus larvae. This was verified by the identification of plankton in the gut content of the fish and by the high density of plankton present in the polluted water...
Anti-malarial activity of Holarrhena antidysenterica and Viola canescens, plants traditionally used against malaria in the Garhwal region of north-west HimalayaGaurav Verma
National Institute of Malaria Research, Field Unit, Hardwar 249403, India
Malar J 10:20. 2011
..The present study shows evaluation of anti-malarial effects of two plants commonly used against malaria in the Garhwal region of north-west Himalaya, in order to discover the herbal-based medicine...
In vitro antiprotozoal activity of some xanthones isolated from the roots of Andrographis paniculataVirendra K Dua
National Institute of Malaria Research, Field Unit, Sector III, BHEL, Hardwar 249 403, India
Phytother Res 23:126-8. 2009
..6 microg/ml and 8 microg/ml respectively. Xanthones from the roots of Andrographis paniculata exhibited promising anti-protozoal activity and these compounds could be chemically modified to obtain a more potent product...
Larvicidal activity of neem oil (Azadirachta indica) formulation against mosquitoesVirendra K Dua
National Institute of Malaria Research, Field Unit, Sector III, BHEL, Hardwar, India
Malar J 8:124. 2009
..Azadirachta indica (Meliaceae) and its derived products have shown a variety of insecticidal properties. The present paper discusses the larvicidal activity of neem-based biopesticide for the control of mosquitoes...
Population cytogenetic and molecular evidence for existence of a new species in Anopheles fluviatilis complex (Diptera: Culicidae)Nutan Nanda
National Institute of Malaria Research, Sector 8, Dwarka, New Delhi 110077, India
Infect Genet Evol 13:218-23. 2013
..With the discovery of new species in the Fluviatilis Complex, in-depth studies are required to know its distribution pattern and biological characteristics and to ascertain its role in malaria transmission...
Larvicidal activity of Hibiscus abelmoschus Linn. (Malvaceae) against mosquitoesVirendra K Dua
Malaria Research Centre, Field Station, Sector III, BHEL, Hardwar 249 403, India
J Am Mosq Control Assoc 22:155-7. 2006
..1% reduction of larval An. stephensi in a tank, whereas 87.4% reduction of larval Cx. quinquefaisciatus occurred in a blocked drain 24 h after application of HAM-4 under field conditions...
Insecticidal and genotoxic activity of Psoralea corylifolia Linn. (Fabaceae) against Culex quinquefasciatus Say, 1823Virendra K Dua
National Institute of Malaria Research, Sector 3, Health Centre, Field Unit BHEL, Ranipur, Hardwar, Uttrakhand, 249403, India
Parasit Vectors 6:30. 2013
..abstract:..
Bio-monitoring of persistent organochlorines in human milk and blood samples from sub-Himalayan region of IndiaSwapnil Rai
National Institute of Malaria Research, Field Station, Sec 3, Health Centre, BHEL, Haridwar, India
Bull Environ Contam Toxicol 89:592-7. 2012
..The study showed much higher concentrations of organochlorine residue contamination in the Garhwal region as compared to other parts of India. Risk assessments for infants were also calculated and were found within WHO limits...