Roland M du Bois

Summary

Publications

  1. ncbi request reprint Peripheral-type benzodiazepine receptors in bronchoalveolar lavage cells of patients with interstitial lung disease
    Howard M Branley
    Imperial College London, Hammersmith Campus, London, UK
    Nucl Med Biol 34:553-8. 2007
  2. doi request reprint Idiopathic pulmonary fibrosis: lung function is a clinically meaningful endpoint for phase III trials
    Roland M du Bois
    Respiratory Medicine, Imperial College, London, UK
    Am J Respir Crit Care Med 186:712-5. 2012
  3. doi request reprint Ascertainment of individual risk of mortality for patients with idiopathic pulmonary fibrosis
    Roland M du Bois
    Imperial College, 1B Manresa Road, London, UK
    Am J Respir Crit Care Med 184:459-66. 2011
  4. doi request reprint An earlier and more confident diagnosis of idiopathic pulmonary fibrosis
    Roland M du Bois
    Imperial College London, UK
    Eur Respir Rev 21:141-6. 2012
  5. doi request reprint Forced vital capacity in patients with idiopathic pulmonary fibrosis: test properties and minimal clinically important difference
    Roland M du Bois
    Imperial College, London, UK
    Am J Respir Crit Care Med 184:1382-9. 2011
  6. doi request reprint Six-minute-walk test in idiopathic pulmonary fibrosis: test validation and minimal clinically important difference
    Roland M du Bois
    National Heart and Lung Institute, Imperial College, London, United Kingdom
    Am J Respir Crit Care Med 183:1231-7. 2011
  7. doi request reprint Sarcoidosis HLA class II genotyping distinguishes differences of clinical phenotype across ethnic groups
    Hiroe Sato
    Clinical Genomics Group, Imperial College London, London SW3 6LR, UK
    Hum Mol Genet 19:4100-11. 2010
  8. doi request reprint PET scanning of macrophages in patients with scleroderma fibrosing alveolitis
    Howard M Branley
    Imperial College London, Hammersmith Campus, London, UK
    Nucl Med Biol 35:901-9. 2008
  9. ncbi request reprint 6-Minute walk distance is an independent predictor of mortality in patients with idiopathic pulmonary fibrosis
    Roland M du Bois
    London, UK
    Eur Respir J 43:1421-9. 2014
  10. doi request reprint Fibroblast-specific perturbation of transforming growth factor beta signaling provides insight into potential pathogenic mechanisms of scleroderma-associated lung fibrosis: exaggerated response to alveolar epithelial injury in a novel mouse model
    Rachel K Hoyles
    Center for Rheumatology, Royal Free and University College Medical School, and Interstitial Royal Brompton Hospital, London, UK
    Arthritis Rheum 58:1175-88. 2008

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Peripheral-type benzodiazepine receptors in bronchoalveolar lavage cells of patients with interstitial lung disease
    Howard M Branley
    Imperial College London, Hammersmith Campus, London, UK
    Nucl Med Biol 34:553-8. 2007
    ....
  2. doi request reprint Idiopathic pulmonary fibrosis: lung function is a clinically meaningful endpoint for phase III trials
    Roland M du Bois
    Respiratory Medicine, Imperial College, London, UK
    Am J Respir Crit Care Med 186:712-5. 2012
    ....
  3. doi request reprint Ascertainment of individual risk of mortality for patients with idiopathic pulmonary fibrosis
    Roland M du Bois
    Imperial College, 1B Manresa Road, London, UK
    Am J Respir Crit Care Med 184:459-66. 2011
    ..Several predictors of mortality in patients with idiopathic pulmonary fibrosis have been described; however, there is a need for a practical and accurate method of quantifying the prognosis of individual patients...
  4. doi request reprint An earlier and more confident diagnosis of idiopathic pulmonary fibrosis
    Roland M du Bois
    Imperial College London, UK
    Eur Respir Rev 21:141-6. 2012
    ..The course of disease in IPF is unpredictable, but the importance of an early diagnosis is clear, as individuals with less severe lung function abnormalities have a better prognosis...
  5. doi request reprint Forced vital capacity in patients with idiopathic pulmonary fibrosis: test properties and minimal clinically important difference
    Roland M du Bois
    Imperial College, London, UK
    Am J Respir Crit Care Med 184:1382-9. 2011
    ..Evidence regarding its measurement properties and minimal clinically important difference (MCID) in this population is limited...
  6. doi request reprint Six-minute-walk test in idiopathic pulmonary fibrosis: test validation and minimal clinically important difference
    Roland M du Bois
    National Heart and Lung Institute, Imperial College, London, United Kingdom
    Am J Respir Crit Care Med 183:1231-7. 2011
    ..Performance characteristics in patients with idiopathic pulmonary fibrosis (IPF) have not been systematically evaluated...
  7. doi request reprint Sarcoidosis HLA class II genotyping distinguishes differences of clinical phenotype across ethnic groups
    Hiroe Sato
    Clinical Genomics Group, Imperial College London, London SW3 6LR, UK
    Hum Mol Genet 19:4100-11. 2010
    ..We show that distinct sarcoidosis phenotypes have similar genetic associations across ethnic groups. The disease case mix differs between centres and may be explained by different ethnic allelic frequencies...
  8. doi request reprint PET scanning of macrophages in patients with scleroderma fibrosing alveolitis
    Howard M Branley
    Imperial College London, Hammersmith Campus, London, UK
    Nucl Med Biol 35:901-9. 2008
    ..A repeatable noninvasive method of assessing disease at a cellular level such as with positron emission tomography (PET) could be of great value in evaluating high-resolution changes in the pathological process...
  9. ncbi request reprint 6-Minute walk distance is an independent predictor of mortality in patients with idiopathic pulmonary fibrosis
    Roland M du Bois
    London, UK
    Eur Respir J 43:1421-9. 2014
    ..75 (0.71-0.79)). Both 6MWD and change in 6MWD are independent predictors of mortality in patients with IPF. The addition of 6MWD to the clinical prediction model improves model discrimination compared with the original model. ..
  10. doi request reprint Fibroblast-specific perturbation of transforming growth factor beta signaling provides insight into potential pathogenic mechanisms of scleroderma-associated lung fibrosis: exaggerated response to alveolar epithelial injury in a novel mouse model
    Rachel K Hoyles
    Center for Rheumatology, Royal Free and University College Medical School, and Interstitial Royal Brompton Hospital, London, UK
    Arthritis Rheum 58:1175-88. 2008
    ....
  11. doi request reprint Genetic variation and response to morphine in cancer patients: catechol-O-methyltransferase and multidrug resistance-1 gene polymorphisms are associated with central side effects
    Joy R Ross
    St Joseph s Hospice, and Department of Clinical Genomics, Imperial College, London, United Kingdom
    Cancer 112:1390-403. 2008
    ..Central side effects, such as drowsiness, confusion, and hallucinations, can limit the use of opioids in clinical practice...
  12. doi request reprint Smoking-related emphysema is associated with idiopathic pulmonary fibrosis and rheumatoid lung
    Katerina M Antoniou
    Interstitial Lung Disease Unit, Royal Brompton Hospital, London, UK
    Respirology 18:1191-6. 2013
    ....
  13. ncbi request reprint Bronchoalveolar lavage cellular profiles in patients with systemic sclerosis-associated interstitial lung disease are not predictive of disease progression
    Nicole S L Goh
    Royal Brompton Hospital and National Heart and Lung Institute, London, UK
    Arthritis Rheum 56:2005-12. 2007
    ..To evaluate the prognostic value of bronchoalveolar lavage (BAL) cellular profiles in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD)...
  14. ncbi request reprint Endothelin is a downstream mediator of profibrotic responses to transforming growth factor beta in human lung fibroblasts
    Xu Shi-Wen
    Royal Free Hospital, University College London, London, UK
    Arthritis Rheum 56:4189-94. 2007
    ..The goal of this study was to assess whether ET-1 is a downstream mediator of the profibrotic effects of TGFbeta in lung fibroblasts...
  15. doi request reprint Ocular features in neurosarcoidosis
    Victor Menezo
    Department of Clinical Ophthalmology, Institute of Ophthalmology, Moorfields Eye Hospital, London, UK
    Ocul Immunol Inflamm 17:170-8. 2009
    ..To determine the type of ocular involvement in patients with neurosarcoidosis, and evaluate whether the type of eye involvement may help in the diagnosis of neurosarcoidosis...
  16. ncbi request reprint Variation in iron homeostasis genes between patients with ARDS and healthy control subjects
    Anna L Lagan
    Unit of Critical Care, Royal Brompton Hospital, London, UK
    Chest 133:1302-11. 2008
    ..Evidence suggests that genetic predisposition is relevant to the pathogenesis of ARDS. We therefore explored the hypothesis that polymorphisms from a panel of genes encoding iron-metabolizing proteins determine susceptibility to ARDS...
  17. ncbi request reprint Association between heat shock protein 70/Hom genetic polymorphisms and uveitis in patients with sarcoidosis
    Paolo Spagnolo
    Clinical Genomic Group, National Heart and Lung Institute, Department of Occupational and Environmental Medicine, Imperial College, London, United Kingdom
    Invest Ophthalmol Vis Sci 48:3019-25. 2007
    ..HSP70 molecules play a key role in the immune response by functioning both as chaperones and as inducers of proinflammatory cytokine secretion...