Christiane Drechsler

Summary

Publications

  1. pmc Vitamin D deficiency is associated with sudden cardiac death, combined cardiovascular events, and mortality in haemodialysis patients
    Christiane Drechsler
    Department of Internal Medicine 1, Division of Nephrology, University of Wurzburg, Oberdürrbacher Str 6, D 97080 Wurzburg, Germany
    Eur Heart J 31:2253-61. 2010
  2. pmc Homoarginine, heart failure, and sudden cardiac death in haemodialysis patients
    Christiane Drechsler
    Department of Internal Medicine 1, Division of Nephrology, University of Wurzburg, Wurzburg, Germany
    Eur J Heart Fail 13:852-9. 2011
  3. doi request reprint Bone alkaline phosphatase and mortality in dialysis patients
    Christiane Drechsler
    Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
    Clin J Am Soc Nephrol 6:1752-9. 2011
  4. doi request reprint Vitamin D status and clinical outcomes in incident dialysis patients: results from the NECOSAD study
    Christiane Drechsler
    1Department of Clinical Epidemiology Leiden University Medical Center, Leiden, The Netherlands
    Nephrol Dial Transplant 26:1024-32. 2011
  5. doi request reprint Changes in parathyroid hormone, body mass index and the association with mortality in dialysis patients
    Christiane Drechsler
    Department of Clinical Epidemiology, LUMC, Leiden, The Netherlands
    Nephrol Dial Transplant 26:1340-6. 2011
  6. doi request reprint Glycemic control and cardiovascular events in diabetic hemodialysis patients
    Christiane Drechsler
    Department of Medicine, Division of Nephrology, University Hospital, Oberdürrbacherstrasse 6, D 97080 Wurzburg, Germany
    Circulation 120:2421-8. 2009
  7. doi request reprint Wasting and sudden cardiac death in hemodialysis patients: a post hoc analysis of 4D (Die Deutsche Diabetes Dialyse Studie)
    Christiane Drechsler
    Department of Medicine, Division of Nephrology, University Hospital Wurzburg, Germany
    Am J Kidney Dis 58:599-607. 2011
  8. doi request reprint Effect of atorvastatin on inflammation and outcome in patients with type 2 diabetes mellitus on hemodialysis
    Vera Krane
    Division of Nephrology, University Clinic, Wurzburg, Germany
    Kidney Int 74:1461-7. 2008
  9. doi request reprint Association of body mass index with decline in residual kidney function after initiation of dialysis
    Christiane Drechsler
    Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
    Am J Kidney Dis 53:1014-23. 2009
  10. pmc Aldosterone and cortisol affect the risk of sudden cardiac death in haemodialysis patients
    Christiane Drechsler
    Division of Nephrology, Department of Internal Medicine 1, University Hospital Wurzburg, University of Wurzburg, Oberdürrbacherstr 6, D 97080, Wurzburg, Germany
    Eur Heart J 34:578-87. 2013

Detail Information

Publications24

  1. pmc Vitamin D deficiency is associated with sudden cardiac death, combined cardiovascular events, and mortality in haemodialysis patients
    Christiane Drechsler
    Department of Internal Medicine 1, Division of Nephrology, University of Wurzburg, Oberdürrbacher Str 6, D 97080 Wurzburg, Germany
    Eur Heart J 31:2253-61. 2010
    ..Accumulating evidence suggests a role of vitamin D for myocardial and overall health. This study investigated the impact of vitamin D status on cardiovascular outcomes and fatal infections in haemodialysis patients...
  2. pmc Homoarginine, heart failure, and sudden cardiac death in haemodialysis patients
    Christiane Drechsler
    Department of Internal Medicine 1, Division of Nephrology, University of Wurzburg, Wurzburg, Germany
    Eur J Heart Fail 13:852-9. 2011
    ..Homoarginine deficiency may lead to decreased nitric oxide availability and endothelial dysfunction. Based on this rationale we assessed whether homoarginine deficiency is a risk factor for SCD in dialysis patients...
  3. doi request reprint Bone alkaline phosphatase and mortality in dialysis patients
    Christiane Drechsler
    Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
    Clin J Am Soc Nephrol 6:1752-9. 2011
    ..The aim of this study was to assess the effect of bone-specific AP (BAP) on morbidity and mortality in dialysis patients...
  4. doi request reprint Vitamin D status and clinical outcomes in incident dialysis patients: results from the NECOSAD study
    Christiane Drechsler
    1Department of Clinical Epidemiology Leiden University Medical Center, Leiden, The Netherlands
    Nephrol Dial Transplant 26:1024-32. 2011
    ..We aimed to elucidate whether European dialysis patients with low 25-hydroxyvitamin D (25(OH)D) levels are at increased risk of mortality and specific fatal events...
  5. doi request reprint Changes in parathyroid hormone, body mass index and the association with mortality in dialysis patients
    Christiane Drechsler
    Department of Clinical Epidemiology, LUMC, Leiden, The Netherlands
    Nephrol Dial Transplant 26:1340-6. 2011
    ..Obesity is associated with secondary hyperparathyroidism in the general population. It is unknown whether body mass index (BMI) affects parathyroid hormone (PTH) level and its association with mortality in dialysis patients...
  6. doi request reprint Glycemic control and cardiovascular events in diabetic hemodialysis patients
    Christiane Drechsler
    Department of Medicine, Division of Nephrology, University Hospital, Oberdürrbacherstrasse 6, D 97080 Wurzburg, Germany
    Circulation 120:2421-8. 2009
    ..Poor glycemic control is associated with cardiovascular comorbidities in the general population. This study investigated the impact of glycemic control on cardiac and vascular outcomes in diabetic hemodialysis patients...
  7. doi request reprint Wasting and sudden cardiac death in hemodialysis patients: a post hoc analysis of 4D (Die Deutsche Diabetes Dialyse Studie)
    Christiane Drechsler
    Department of Medicine, Division of Nephrology, University Hospital Wurzburg, Germany
    Am J Kidney Dis 58:599-607. 2011
    ..This study examined the effects of wasting on the various components of cardiovascular outcome and deaths caused by infection in hemodialysis patients...
  8. doi request reprint Effect of atorvastatin on inflammation and outcome in patients with type 2 diabetes mellitus on hemodialysis
    Vera Krane
    Division of Nephrology, University Clinic, Wurzburg, Germany
    Kidney Int 74:1461-7. 2008
    ....
  9. doi request reprint Association of body mass index with decline in residual kidney function after initiation of dialysis
    Christiane Drechsler
    Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
    Am J Kidney Dis 53:1014-23. 2009
    ..Our aim was to study the effects of body mass index (BMI) on decline in kidney function and risk to develop anuria after initiation of dialysis therapy...
  10. pmc Aldosterone and cortisol affect the risk of sudden cardiac death in haemodialysis patients
    Christiane Drechsler
    Division of Nephrology, Department of Internal Medicine 1, University Hospital Wurzburg, University of Wurzburg, Oberdürrbacherstr 6, D 97080, Wurzburg, Germany
    Eur Heart J 34:578-87. 2013
    ..Sudden cardiac death is common and accounts largely for the excess mortality of patients on maintenance dialysis. It is unknown whether aldosterone and cortisol increase the incidence of sudden cardiac death in dialysis patients...
  11. pmc The association between parathyroid hormone and mortality in dialysis patients is modified by wasting
    Christiane Drechsler
    Division of Nephrology, Department of Medicine, University of Wurzburg, Germany
    Nephrol Dial Transplant 24:3151-7. 2009
    ..We hypothesized that wasting, a common condition potentially related to adynamic bone disease, modifies the association of PTH with mortality and cardiovascular events (CVE), respectively...
  12. pmc Change in N-terminal-pro-B-type-natriuretic-peptide and the risk of sudden death, stroke, myocardial infarction, and all-cause mortality in diabetic dialysis patients
    Karl Winkler
    Division of Clinical Chemistry, Department of Medicine, University Medical Center Freiburg, Hugstetter Straße 55, 79106 Freiburg, Germany
    Eur Heart J 29:2092-9. 2008
    ..This study examined the effect of baseline and change from baseline NT-pro-BNP on cardiovascular outcome and mortality in haemodialysis patients...
  13. pmc Copeptin levels associate with cardiovascular events in patients with ESRD and type 2 diabetes mellitus
    Wiebke Fenske
    Department of Medicine, Division of Nephrology, University of Wurzburg, Wurzburg, Germany
    J Am Soc Nephrol 22:782-90. 2011
    ..Whether vasopressin receptor antagonists will improve these outcomes requires further studies...
  14. pmc Predicting erythropoietin resistance in hemodialysis patients with type 2 diabetes
    Andreas Schneider
    Department of Medicine, Division of Nephrology, University Hospital Wuerzburg, Wuerzburg, Germany
    BMC Nephrol 14:67. 2013
    ..The aim of this study was to identify predictors for ESA resistance and to develop a prediction model for the risk stratification in these patients...
  15. pmc Homoarginine and progression of chronic kidney disease: results from the Mild to Moderate Kidney Disease Study
    Christiane Drechsler
    Division of Nephrology, Department of Medicine, University of Wurzburg, Wurzburg, Germany
    PLoS ONE 8:e63560. 2013
    ..We aimed to investigate the relation between homoarginine, kidney function and progression of chronic kidney disease (CKD)...
  16. doi request reprint Apolipoprotein E genotype predicts cardiovascular endpoints in dialysis patients with type 2 diabetes mellitus
    Karl Winkler
    Division of Clinical Chemistry, Department of Medicine, University Medical Center Freiburg, Hugstetter Strasse 55, Freiburg, Germany
    Atherosclerosis 208:197-202. 2010
    ..Lipid metabolism is influenced by environmental and genetic factors. Among the latter, the apolipoprotein E (apoE) genotype is known to be associated with CVD risk and thus may affect cardiovascular outcome...
  17. doi request reprint Association of LDL cholesterol and inflammation with cardiovascular events and mortality in hemodialysis patients with type 2 diabetes mellitus
    Vera Krane
    Department of Medicine I, Division of Nephrology, University of Wurzburg, Germany
    Am J Kidney Dis 54:902-11. 2009
    ..In hemodialysis patients, the additive value is unknown. The association between LDL cholesterol level and outcome previously was suggested to be inverse and confounded by inflammation...
  18. pmc The effect of high-flux hemodialysis on hemoglobin concentrations in patients with CKD: results of the MINOXIS study
    Andreas Schneider
    Department of Medicine, Division of Nephrology, University Hospital Wurzburg, Germany
    Clin J Am Soc Nephrol 7:52-9. 2012
    ..This study sought to determine whether high-flux dialysis would help improve markers of renal anemia, inflammation, and oxidative stress compared with low-flux dialysis...
  19. doi request reprint Changes in adiponectin and the risk of sudden death, stroke, myocardial infarction, and mortality in hemodialysis patients
    Christiane Drechsler
    Division of Nephrology, Department of Medicine, University Hospital Wurzburg, Josef Schneider Strasse 2, Würzburg D 97080, Germany
    Kidney Int 76:567-75. 2009
    ..Most likely, this rise is a counter-regulatory response to worsening health in keeping with adiponectin's potential to counteract inflammation...
  20. ncbi request reprint Dyslipidemia, inflammation and dialysis outcomes: what we know now
    Vera Krane
    Department of Medicine, Division of Nephrology, University of Wurzburg, Germany
    Curr Opin Nephrol Hypertens 15:566-70. 2006
    ..The limited prognosis of patients with chronic kidney disease starts when renal function begins to decline...
  21. doi request reprint C-reactive protein and uremia
    Christoph Wanner
    Division of Nephrology, Department of Medicine, University of Wuerzburg, Wurzburg, Germany
    Semin Dial 22:438-41. 2009
    ..So far, no specific pharmacologic treatment, including atorvastatin, has been identified that can substantially reduce CRP and accompanying inflammation...
  22. ncbi request reprint Lipid metabolism in chronic kidney disease: the role of statins in cardiovascular risk
    Christoph Wanner
    University of Wurzburg, Department of Medicine, Division of Nephrology, University Hospital Wurzburg, Wurzburg, Germany
    J Ren Nutr 17:75-8. 2007
    ..This review will focus on dyslipidemia in renal failure and its treatment. The data published so far is summarized and grouped according to the different stages of CKD...
  23. doi request reprint Obesity-related cardiorenal disease: the benefits of bariatric surgery
    Wiebke Fenske
    Department of Internal Medicine, Endocrine and Diabetes Unit, University of Wurzburg, Germany
    Nat Rev Nephrol 9:539-51. 2013
    ..However, further research is required to understand how bariatric surgery acts on the cardiorenal axis, and its pioneering role in novel treatments and interventions for cardiorenal disease. ..
  24. doi request reprint Epidemiology of adrenal crisis in chronic adrenal insufficiency: the need for new prevention strategies
    Stefanie Hahner
    Endocrinology and Diabetes Unit, Department of Medicine I, University of Wurzburg, Oberdürrbacher Str 6, D 97080 Wurzburg, Germany
    Eur J Endocrinol 162:597-602. 2010
    ..Adrenal crisis (AC) is a life-threatening complication of adrenal insufficiency (AI). Here, we evaluated frequency, causes and risk factors of AC in patients with chronic AI...