Aaron Dossey

Summary

Affiliation: Independent Researcher, Policy Advocate, Entrepreneur
Location: Gainesville, FL, USA
URL: http://allthingsbugs.web.officelive.com/default.aspx
Summary:
Skills

Publications

  1. ncbi NMR analysis of Caenorhabditis elegans FLP-18 neuropeptides: implications for NPR-1 activation
    Aaron T Dossey
    McKnight Brain Institute, University of Florida, 100 South Newell Drive, Building 59, Room LG-150, Gainesville, Florida 32611, USA
    Biochemistry 45:7586-97. 2006
  2. ncbi Insects and their chemical weaponry: new potential for drug discovery
    Aaron T Dossey
    Nat Prod Rep 27:1737-57. 2010
  3. ncbi Alkyldimethylpyrazines in the defensive spray of Phyllium westwoodii: a first for order Phasmatodea
    Aaron T Dossey
    Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL 32610 0245, USA
    J Chem Ecol 35:861-70. 2009
  4. ncbi Bacterial attraction and quorum sensing inhibition in Caenorhabditis elegans exudates
    Fatma Kaplan
    Center for Medical, Agricultural and Veterinary Entomology, USDA ARS, Gainesville, FL, USA
    J Chem Ecol 35:878-92. 2009
  5. ncbi Relative configuration of natural products using NMR chemical shifts
    Bing Wang
    Department of Chemistry, Quantum Theory Project, University of Florida, Gainesville, Florida 32611, USA
    J Nat Prod 72:709-13. 2009
  6. ncbi Developmental and geographical variation in the chemical defense of the walkingstick insect Anisomorpha buprestoides
    Aaron T Dossey
    Department of Biochemistry and Molecular Biology, University of Florida, PO Box 100245, Gainesville, FL 32610 0245, USA
    J Chem Ecol 34:584-90. 2008
  7. ncbi Strategy for automated analysis of dynamic metabolic mixtures by NMR. Application to an insect venom
    Fengli Zhang
    National High Magnet Field Laboratory, Florida State University, Tallahassee, Florida 32310, USA
    Anal Chem 79:7748-52. 2007
  8. ncbi Parectadial, a monoterpenoid from the defensive spray of Parectatosoma mocquerysi
    Aaron T Dossey
    Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida 32610, USA
    J Nat Prod 70:1335-8. 2007
  9. ncbi Single insect NMR: A new tool to probe chemical biodiversity
    Aaron T Dossey
    ACS Chem Biol 1:511-4. 2006
  10. ncbi Hierarchical alignment and full resolution pattern recognition of 2D NMR spectra: application to nematode chemical ecology
    Steven L Robinette
    Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida 32610 0245, United States
    Anal Chem 83:1649-57. 2011

Collaborators

Detail Information

Publications10

  1. ncbi NMR analysis of Caenorhabditis elegans FLP-18 neuropeptides: implications for NPR-1 activation
    Aaron T Dossey
    McKnight Brain Institute, University of Florida, 100 South Newell Drive, Building 59, Room LG-150, Gainesville, Florida 32611, USA
    Biochemistry 45:7586-97. 2006
    ..We hypothesize that these loops, along with peptide charge, diminish the activity of this peptide on NPR-1 relative to that of EMPGVLRF-NH2. These results provide some insight into the large amino acid diversity in FLPs...
  2. ncbi Insects and their chemical weaponry: new potential for drug discovery
    Aaron T Dossey
    Nat Prod Rep 27:1737-57. 2010
  3. ncbi Alkyldimethylpyrazines in the defensive spray of Phyllium westwoodii: a first for order Phasmatodea
    Aaron T Dossey
    Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL 32610 0245, USA
    J Chem Ecol 35:861-70. 2009
    ..This is the first report of pyrazines found in the defensive gland spray of phasmid insects, and the first chemical analysis of glandular material from family Phylliidae...
  4. ncbi Bacterial attraction and quorum sensing inhibition in Caenorhabditis elegans exudates
    Fatma Kaplan
    Center for Medical, Agricultural and Veterinary Entomology, USDA ARS, Gainesville, FL, USA
    J Chem Ecol 35:878-92. 2009
    ..Our results demonstrate that C. elegans can attract its bacterial food and has the potential of partially regulating the virulence of bacterial pathogens by inhibiting specific QS systems...
  5. ncbi Relative configuration of natural products using NMR chemical shifts
    Bing Wang
    Department of Chemistry, Quantum Theory Project, University of Florida, Gainesville, Florida 32611, USA
    J Nat Prod 72:709-13. 2009
    ..Complementary to the NOE-based method, a comparison between experimental and calculated NMR chemical shifts can provide an efficient method to assign the relative configuration of natural products...
  6. ncbi Developmental and geographical variation in the chemical defense of the walkingstick insect Anisomorpha buprestoides
    Aaron T Dossey
    Department of Biochemistry and Molecular Biology, University of Florida, PO Box 100245, Gainesville, FL 32610 0245, USA
    J Chem Ecol 34:584-90. 2008
    ..This appears to be the first report of a developmentally regulated change in walkingstick insect chemical defense. Our results suggest a more complex role of these substances in the overall chemical ecology of walkingstick insects...
  7. ncbi Strategy for automated analysis of dynamic metabolic mixtures by NMR. Application to an insect venom
    Fengli Zhang
    National High Magnet Field Laboratory, Florida State University, Tallahassee, Florida 32310, USA
    Anal Chem 79:7748-52. 2007
    ..The method is demonstrated on a metabolic model mixture and is then applied to the unpurified venom mixture of an individual walking stick insect that contains several slowly interconverting and closely related metabolites...
  8. ncbi Parectadial, a monoterpenoid from the defensive spray of Parectatosoma mocquerysi
    Aaron T Dossey
    Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida 32610, USA
    J Nat Prod 70:1335-8. 2007
    ..This work demonstrates the value of walkingstick insects as sources of new bioactive compounds and provides an analytical framework for identifying such substances...
  9. ncbi Single insect NMR: A new tool to probe chemical biodiversity
    Aaron T Dossey
    ACS Chem Biol 1:511-4. 2006
    ..Single-insect variability of venom demonstrates the potential importance of chemical biodiversity at the level of individual animals...
  10. ncbi Hierarchical alignment and full resolution pattern recognition of 2D NMR spectra: application to nematode chemical ecology
    Steven L Robinette
    Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida 32610 0245, United States
    Anal Chem 83:1649-57. 2011
    ..These results demonstrate that the combination of 2D NMR spectra with full-resolution statistical analysis provides a platform for chemical and biological studies in cellular biochemistry, metabolomics, and chemical ecology...