Molecular epidemiology: the impact of molecular biology in epidemiology researchJ S Dorman
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
Rev Med Chil 128:1261-8. 2000
..Molecular epidemiology is at the foundation of this important link, and represents the scientific basis of public health for the 21st Century...
- HLA-DQ locus of the human leukocyte antigen complex and type 1 diabetes mellitus: a HuGE review
J S Dorman
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA 15261, USA
Epidemiol Rev 22:218-27. 2000
- Menopause in type 1 diabetic women: is it premature?
J S Dorman
Department of Epidemiology, Graduate School of Public Health, Pittsburgh, Pennsylvania 15261, USA
Diabetes 50:1857-62. 2001
..76, P < 0.0001) were independent determinants of earlier menopause in our cohort. We hypothesize that an earlier menopause, which resulted in a 17% decrease in reproductive years, is a major unstudied complication of type 1 diabetes...
- Islet cell autoimmunity in white and black children and adolescents with IDDM
I M Libman
Department of Pediatrics, Rangos Research Center, Children s Hospital of Pittsburgh, Diabetes Research Center, Graduate School of Public Health, University of Pittsburgh, Pennsylvania 15213, USA
Diabetes Care 21:1824-7. 1998
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- Was there an epidemic of diabetes in nonwhite adolescents in Allegheny County, Pennsylvania?
I M Libman
Diabetes Research Center, Rangos Research Center, Pittsburgh, PA 15213, USA
Diabetes Care 21:1278-81. 1998
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- IDDM incidence in a multiracial population. The Hawaii IDDM Registry, 1980-1990
S L Patrick
World Health Organization Collaborating Center for Diabetes Research, Registries and Training, Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA
Diabetes Care 20:983-7. 1997
..Because of the multiracial population living in Hawaii, it is an ideal state in which to study the effect of migration on IDDM incidence...
- Progression to insulin-requiring diabetes in seronegative prediabetic subjects: the role of two HLA-DQ high-risk haplotypes
M Pietropaolo
Division of Immunogenetics, Rangos Research Center, Children s Hospital of Pittsburgh, University of Pittsburgh School of Medicine, 3460 Fifth Avenue, Pittsburgh, PA 15213, USA
Diabetologia 45:66-76. 2002
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- Health insurance and the financial impact of IDDM in families with a child with IDDM
T J Songer
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA 15261, USA
Diabetes Care 20:577-84. 1997
..To examine the health insurance experience and out-of-pocket health care costs of families with a child with IDDM...
- Temporal trends in spontaneous abortion associated with Type 1 diabetes
J S Dorman
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA 15261, USA
Diabetes Res Clin Pract 43:41-7. 1999
..7%; P>0.05). Temporal changes in medical care for women with diabetes (i.e. self-monitoring of glycemic control) may have contributed to a recent reduction in spontaneous abortions associated with maternal Type 1 diabetes...
- Mortality trends in type 1 diabetes. The Allegheny County (Pennsylvania) Registry 1965-1999
R Nishimura
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pennsylvania, USA
Diabetes Care 24:823-7. 2001
..This improvement is consistent with the introduction of HbA1 testing, home blood glucose monitoring, and improved blood pressure therapy in the 1980s...
- 14th International HLA and Immunogenetics Workshop: report on the HLA component of type 1 diabetes
A Steenkiste
Department of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
Tissue Antigens 69:214-25. 2007
..The above studies underscore the importance of refining our understanding of susceptibility associated with genes in the HLA complex...
- D6S265*15 marks a DRB1*15, DQB1*0602 haplotype associated with attenuated protection from type 1 diabetes mellitus
A M Valdes
Department of Integrative Biology, University of California, Berkeley, CA, USA
Diabetologia 48:2540-3. 2005
..The aim of this study was to identify markers within the HLA region that differentiate DQB1*0602 haplotypes and show different associations with disease risk...
- Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: a meta-analysis
G Thomson
Department of Integrative Biology, University of California, Berkeley, CA 94720 3140, USA
Tissue Antigens 70:110-27. 2007
..Our results show that meta-analyses and use of the P/C ratio and rankings thereof can be valuable in determining T1D risk factors at the haplotype and amino acid residue levels...
