Pascal Dolle

Summary

Publications

  1. ncbi request reprint Retinoic acid in development: towards an integrated view
    Karen Niederreither
    Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA
    Nat Rev Genet 9:541-53. 2008
  2. pmc Transcriptomic analysis of murine embryos lacking endogenous retinoic acid signaling
    Marie Paschaki
    Developmental Biology and Stem Cells Department, Institut de Genetique et de Biologie Moleculaire et Cellulaire IGBMC, Centre National de la Recherche Scientifique Unité Mixte de Recherche 7104, Institut National de la Santé et de la Recherche Médicale Unité 964, Universite de Strasbourg, Illkirch Strasbourg, France
    PLoS ONE 8:e62274. 2013
  3. pmc Retinoic acid regulates olfactory progenitor cell fate and differentiation
    Marie Paschaki
    Laboratory for Sensory Development, RIKEN Center for Developmental Biology, Kobe 650 0047, Japan
    Neural Dev 8:13. 2013
  4. pmc miRNeye: a microRNA expression atlas of the mouse eye
    Marianthi Karali
    Telethon Institute for Genetics and Medicine, Via P Castellino 111, Naples, Italy
    BMC Genomics 11:715. 2010
  5. doi request reprint Fate of retinoic acid-activated embryonic cell lineages
    Pascal Dolle
    IGBMC Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France
    Dev Dyn 239:3260-74. 2010
  6. pmc Developmental expression of retinoic acid receptors (RARs)
    Pascal Dolle
    IGBMC Institut de Génétique et de Biologie Moléculaire et Cellulaire, France
    Nucl Recept Signal 7:e006. 2009
  7. pmc Retinoic acid-dependent signaling pathways and lineage events in the developing mouse spinal cord
    Marie Paschaki
    Development and Stem Cells Department, Centre National de la Recherche Scientifique UMR 7104, Institut National de la Santé et de la Recherche Médicale U 964, Universite de Strasbourg, Illkirch Strasbourg, France
    PLoS ONE 7:e32447. 2012
  8. doi request reprint Dynamic expression of the retinoic acid-synthesizing enzyme retinol dehydrogenase 10 (rdh10) in the developing mouse brain and sensory organs
    Raymond Romand
    IGBMC Institut de Génétique et de Biologie Moléculaire et Cellulaire, BP 10142, Illkirch, F 67400 France
    J Comp Neurol 508:879-92. 2008
  9. doi request reprint Retinoic acid deficiency impairs the vestibular function
    Raymond Romand
    IGBMC Institut de Génétique et de Biologie Moléculaire et Cellulaire, BP 10142, Illkirch F 67404, France
    J Neurosci 33:5856-66. 2013
  10. ncbi request reprint The oxidizing enzyme CYP26a1 tightly regulates the availability of retinoic acid in the gastrulating mouse embryo to ensure proper head development and vasculogenesis
    Vanessa Ribes
    IGBMC, Institut de Genetique et de Biologie Moleculaire et Cellulaire, BP 10142, Illkirch, France
    Dev Dyn 236:644-53. 2007

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Retinoic acid in development: towards an integrated view
    Karen Niederreither
    Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA
    Nat Rev Genet 9:541-53. 2008
    ..Some of these functions could be maintained throughout the life of an organism to regulate cell-lineage decisions and/or the differentiation of stem cell populations, highlighting possibilities for regenerative medicine...
  2. pmc Transcriptomic analysis of murine embryos lacking endogenous retinoic acid signaling
    Marie Paschaki
    Developmental Biology and Stem Cells Department, Institut de Genetique et de Biologie Moleculaire et Cellulaire IGBMC, Centre National de la Recherche Scientifique Unité Mixte de Recherche 7104, Institut National de la Santé et de la Recherche Médicale Unité 964, Universite de Strasbourg, Illkirch Strasbourg, France
    PLoS ONE 8:e62274. 2013
    ..Overall, these data give an overview of the gene expression changes resulting from embryonic RA deficiency, and provide new candidate genes and pathways that may help understanding retinoid-dependent molecular events...
  3. pmc Retinoic acid regulates olfactory progenitor cell fate and differentiation
    Marie Paschaki
    Laboratory for Sensory Development, RIKEN Center for Developmental Biology, Kobe 650 0047, Japan
    Neural Dev 8:13. 2013
    ....
  4. pmc miRNeye: a microRNA expression atlas of the mouse eye
    Marianthi Karali
    Telethon Institute for Genetics and Medicine, Via P Castellino 111, Naples, Italy
    BMC Genomics 11:715. 2010
    ..MicroRNAs (miRNAs) are key regulators of biological processes. To define miRNA function in the eye, it is essential to determine a high-resolution profile of their spatial and temporal distribution...
  5. doi request reprint Fate of retinoic acid-activated embryonic cell lineages
    Pascal Dolle
    IGBMC Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France
    Dev Dyn 239:3260-74. 2010
    ..These are described in relationship with current models of RA activity in various developmental systems, including the embryonic caudal region, limb buds, hindbrain, sensory organs, and heart...
  6. pmc Developmental expression of retinoic acid receptors (RARs)
    Pascal Dolle
    IGBMC Institut de Génétique et de Biologie Moléculaire et Cellulaire, France
    Nucl Recept Signal 7:e006. 2009
    ..These pleiotropic roles are summarized hereafter in relationship to the receptors' expression patterns...
  7. pmc Retinoic acid-dependent signaling pathways and lineage events in the developing mouse spinal cord
    Marie Paschaki
    Development and Stem Cells Department, Centre National de la Recherche Scientifique UMR 7104, Institut National de la Santé et de la Recherche Médicale U 964, Universite de Strasbourg, Illkirch Strasbourg, France
    PLoS ONE 7:e32447. 2012
    ....
  8. doi request reprint Dynamic expression of the retinoic acid-synthesizing enzyme retinol dehydrogenase 10 (rdh10) in the developing mouse brain and sensory organs
    Raymond Romand
    IGBMC Institut de Génétique et de Biologie Moléculaire et Cellulaire, BP 10142, Illkirch, F 67400 France
    J Comp Neurol 508:879-92. 2008
    ....
  9. doi request reprint Retinoic acid deficiency impairs the vestibular function
    Raymond Romand
    IGBMC Institut de Génétique et de Biologie Moléculaire et Cellulaire, BP 10142, Illkirch F 67404, France
    J Neurosci 33:5856-66. 2013
    ..Our data thus reveal a previously unrecognized role of Raldh3 in structural and functional development of the vestibular end organs...
  10. ncbi request reprint The oxidizing enzyme CYP26a1 tightly regulates the availability of retinoic acid in the gastrulating mouse embryo to ensure proper head development and vasculogenesis
    Vanessa Ribes
    IGBMC, Institut de Genetique et de Biologie Moleculaire et Cellulaire, BP 10142, Illkirch, France
    Dev Dyn 236:644-53. 2007
    ..We also report a novel role of CYP26A1 during early development of the intra- and extra-embryonic vascular networks...
  11. doi request reprint Retinoic acid signalling during development
    Muriel Rhinn
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, Illkirch, France
    Development 139:843-58. 2012
    ..Here, we provide an overview of the RA biosynthesis, degradation and signalling pathways and review the main functions of this molecule during embryogenesis...
  12. pmc Molars and incisors: show your microarray IDs
    Virginie Laugel-Haushalter
    Developmental Biology and Stem Cells Department, Institut de Genetique et de Biologie Moleculaire et Cellulaire IGBMC, Universite de Strasbourg, BP 10142, 1 rue Laurent Fries, Illkirch Cedex, 67404, France
    BMC Res Notes 6:113. 2013
    ..To identify such signatures, we performed a comparative transcriptomic analysis of developing murine lower incisors, mandibular molars and maxillary molars at the developmental cap stage (E14.5)...
  13. pmc Dynamic expression of retinoic acid-synthesizing and -metabolizing enzymes in the developing mouse inner ear
    Raymond Romand
    Institut Clinique de la Souris, Illkirch, France
    J Comp Neurol 496:643-54. 2006
    ..The downregulation of Cyp26s and the upregulation of Raldhs after birth during inner ear maturation suggest tissue changes in the sensitivity to retinoic acid concentrations...
  14. doi request reprint Combinatorial signalling controls Neurogenin2 expression at the onset of spinal neurogenesis
    Vanessa Ribes
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, INSERM U 596, CNRS UMR 7104, Universite Louis Pasteur, 1 rue Laurent Fries, Illkirch, BP 10142 F 67400, France
    Dev Biol 321:470-81. 2008
    ..Our data thus support a model where signal integration at the level of a single enhancer constitutes a key mechanism to control the onset of neurogenesis...
  15. ncbi request reprint Expression of the murine retinol dehydrogenase 10 (Rdh10) gene correlates with many sites of retinoid signalling during embryogenesis and organ differentiation
    Laura Cammas
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, INSERM, U596, CNRS, UMR 7104, Illkirch, France
    Dev Dyn 236:2899-908. 2007
    ..These data implicate the retinol to retinaldehyde conversion as the first step in the tissue-specific regulation of retinoic acid synthesis, at least in mammalian embryos...
  16. doi request reprint Genetic inactivation of prokineticin receptor-1 leads to heart and kidney disorders
    Mounia Boulberdaa
    Centre National de la Recherche Scientifique, Universite de Strasbourg, UMR 7242, Ecole Superieure de Biotechnologie de Strasbourg, Illkirch, France
    Arterioscler Thromb Vasc Biol 31:842-50. 2011
    ..Observations of cardiac and renal toxicity in cancer patients treated with antiangiogenic compounds led us to explore how PKR1 signaling functioned in heart and kidney in vivo...
  17. pmc Endogenous retinoic acid regulates cardiac progenitor differentiation
    Song Chang Lin
    Departments of Medicine and Molecular and Cellular Biology, Center for Cardiovascular Development, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 107:9234-9. 2010
    ..Hence, although lack of RA signaling increases cardiac SP numbers, simultaneous reductions in Fgf signaling reduce cardiomyocyte differentiation, possibly accounting for long-term defects in myocardial growth...
  18. ncbi request reprint Molecular cloning, genomic structure, and expression analysis of the mouse transcriptional intermediary factor 1 gamma gene
    Kai Ping Yan
    Institut de Genetique et de Biologie Moleculaire et Cellulaire IGBMC, CNRS INSERM ULP College de France, BP 10142, 67 404 Illkirch Cedex, France
    Gene 334:3-13. 2004
    ..Taken together, these results indicate-and serve as a basis for investigating-a possible involvement of Tif1gamma in the control of embryonic development and spermatogenesis...
  19. pmc RSK2 is a modulator of craniofacial development
    Virginie Laugel-Haushalter
    Institute of Genetics and Molecular and Cellular Biology IGBMC, Centre National de la Recherche Scientifique UMR 7104, Institut National de la Santé et de la Recherche Médicale U 964, University of Strasbourg, Illkirch, France
    PLoS ONE 9:e84343. 2014
    ..Craniofacial and dental anomalies encountered in this rare disease have been poorly characterized...
  20. ncbi request reprint Retinoic acid regulates morphogenesis and patterning of posterior foregut derivatives
    Zengxin Wang
    Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Dev Biol 297:433-45. 2006
    ..Our data implicate RA as a regulator of gene expression in the early embryonic lung and stomach region upstream of Hox, Tbx and FGF10 signaling...