[The role of estrogens in angiogenesis in the female reproductive system]Bozena Dobrzycka
Zakład Pielegniartwa Połosniczo Ginekkologicznego Uniwersytetu Medycznego, Białystok
Endokrynol Pol 60:210-4. 2009
..A clear association between estrogen, estrogen receptor expression by endothelial cells and angiogenic activity has been confirmed. This minireview will discuss the recent progress in research into the role of estrogens in angiogenesis...
- The prognostic significance of the immunohistochemical expression of P53 and BCL-2 in endometrial cancer
Bozena Dobrzycka
Department of Obstetrics, Gynecology and Obstetrics Gynecological Care, Medical University of Bialystok, Poland
Folia Histochem Cytobiol 49:631-5. 2011
..001 and 0.002) and correlated with a decrease in overall survival in type I endometrial cancer (p = 0.014). Thus, the prognostic value of these biomarkers in endometrial cancer needs to be further investigated...
Mutations of the KRAS oncogene in endometrial hyperplasia and carcinomaBozena Dobrzycka
Department of Gynecological and Obstetrical Nursing, Medical University of Białystok, Białystok, Poland
Folia Histochem Cytobiol 47:65-8. 2009
..We conclude that KRAS mutation is a relatively common event in endometrial carcinogenesis, but with no prognostic value...
- Biomarkers as prognostic factors in endometrial cancer
Bozena Dobrzycka
Department of Obstetrics, Gynecology and Obstetrics Gynecological Care, Medical University of Bialystok, Poland
Folia Histochem Cytobiol 48:319-22. 2010
....
- Tumor necrosis factor-alpha and its receptors in epithelial ovarian cancer
Bozena Dobrzycka
Department of Obstetrics, Gynecology and Obstetrics Gynecological Care, Medical University of Bialystok, Bialystok, Poland
Folia Histochem Cytobiol 47:609-13. 2009
..Thus, the clinical value of activated TNF system in epithelial ovarian cancer needs to be further investigated...
- Mutations in the KRAS gene in ovarian tumors
Bozena Dobrzycka
Department of Gynecological and Obstetrical Nursing, Medical University of Białystok, Poland
Folia Histochem Cytobiol 47:221-4. 2009
..Mutation frequency was correlated with the histological type of tumor, but not with stage, grade or patients age...
- Prognostic significance of smac/DIABLO in endometrioid endometrial cancer
Bozena Dobrzycka
Department of Obstetrics, Gynecology and Obstetrics Gynecological Care, Medical University of Bialystok, Poland
Folia Histochem Cytobiol 48:678-81. 2010
..043). The study demonstrated that negative smac/DIABLO expression was a poor prognostic sign...
- Circulating free DNA, p53 antibody and mutations of KRAS gene in endometrial cancer
Bozena Dobrzycka
Department of Obstetrics and Gynecology, Medical University of Bialystok, Bialystok, Poland
Int J Cancer 127:612-21. 2010
..The association between tumor cells related to CFDNA and p53-Ab with Type II tumor suggests that it might potentially serve as a marker in predicting the prognosis and offers a possibility to individualize treatment regimen...
- Serum levels of VEGF and VEGF-C in patients with endometrial cancer
Bozena Dobrzycka
Department of Obstetrics, Gynecology and Obstetrics Gynecological Care, Medical University of Bialystok, Poland
Eur Cytokine Netw 22:45-51. 2011
..Thus, in type II EC patients with high preoperative levels of VEGF-C, pelvic and para-aortic lymphadenectomy should be performed. However, the value of longitudinal measurements of the markers used is yet to be determined...
- Circulating levels of TNF-alpha and its soluble receptors in the plasma of patients with epithelial ovarian cancer
Bozena Dobrzycka
Department of Gynecological and Obstetrical Nursing, Medical University of Bialystok, Bialystok, Poland
Eur Cytokine Netw 20:131-4. 2009
..Thus, the clinical value of an activated TNF system in EOC needs to be further investigated...
- Prognostic significance of VEGF and its receptors in endometrioid endometrial cancer
Bozena Dobrzycka
Department of Obstetrics, Gynecology and Obstetrics Gynecological Care, Medical University of Bialystok, Poland
Ginekol Pol 81:422-5. 2010
..Angiogenesis is of crucial importance for endometrial tumor growth and Vascular Endothelial Growth Factor (VEGF) is the key mediator of angiogenesis...
- Pretreatment serum levels of bFGF and VEGF and its clinical significance in endometrial carcinoma
Bozena Dobrzycka
Department of Obstetrics, Gynecology and Maternity Care, Medical University of Bialystok, Poland
Gynecol Oncol 128:454-60. 2013
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