Jasmin Divers

Summary

Publications

  1. pmc Cerebral white matter hyperintensity in African Americans and European Americans with type 2 diabetes
    Jasmin Divers
    Division of Public Health Sciences, Wake Forest School of Medicine, Winston Salem, North Carolina Electronic address
    J Stroke Cerebrovasc Dis 22:e46-52. 2013
  2. pmc JC polyoma virus interacts with APOL1 in African Americans with nondiabetic nephropathy
    Jasmin Divers
    Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston Salem, North Carolina, USA
    Kidney Int 84:1207-13. 2013
  3. pmc Association of APOL1 variants with mild kidney disease in the first-degree relatives of African American patients with non-diabetic end-stage renal disease
    Barry I Freedman
    Department of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston Salem, North Carolina 27157 1053, USA
    Kidney Int 82:805-11. 2012
  4. pmc Sclerostin is positively associated with bone mineral density in men and women and negatively associated with carotid calcified atherosclerotic plaque in men from the African American-Diabetes Heart Study
    Thomas C Register
    Departments of Pathology T C R, Public Health Sciences J D, L E W, C D L, Radiology T C R, J J C, R C H, and Internal Medicine Nephrology B I F and Center for Genomics and Personalized Medicine Research D W B, N D P, J X, S C S, Wake Forest School of Medicine, Winston Salem, North Carolina 27157 and Department of Pediatric Nephrology K A H, D J D, Washington University School of Medicine, St Louis, Missouri 63110
    J Clin Endocrinol Metab 99:315-21. 2014
  5. pmc Relationships between serum MCP-1 and subclinical kidney disease: African American-Diabetes Heart Study
    Mariana Murea
    Department of Internal Medicine Nephrology, Wake Forest School of Medicine, Medical Center Boulevard, Winston Salem, NC, 27157 1053, USA
    BMC Nephrol 13:148. 2012
  6. pmc Polymorphisms in MYH9 are associated with diabetic nephropathy in European Americans
    Jessica N Cooke
    Program in Molecular Medicine and Translational Science, Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston Salem, NC, USA
    Nephrol Dial Transplant 27:1505-11. 2012
  7. pmc Sickle cell trait is not independently associated with susceptibility to end-stage renal disease in African Americans
    Pamela J Hicks
    Department of Biochemistry, Wake Forest School of Medicine, Winston Salem, North Carolina, USA 27157 1053
    Kidney Int 80:1339-43. 2011
  8. pmc Relationships between serum adiponectin and bone density, adiposity and calcified atherosclerotic plaque in the African American-Diabetes Heart Study
    Thomas C Register
    Department of Pathology, Wake Forest School of Medicine, Winston Salem, North Carolina 27157, USA
    J Clin Endocrinol Metab 98:1916-22. 2013
  9. pmc Gene-gene interactions in APOL1-associated nephropathy
    Jasmin Divers
    Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston Salem, NC, USA
    Nephrol Dial Transplant 29:587-94. 2014
  10. pmc Admixture mapping of coronary artery calcified plaque in African Americans with type 2 diabetes mellitus
    Jasmin Divers
    Departments of Biostatistical Sciences, Wake Forest School of Medicine, Winston Salem, NC 27157 1053, USA
    Circ Cardiovasc Genet 6:97-105. 2013

Collaborators

Detail Information

Publications27

  1. pmc Cerebral white matter hyperintensity in African Americans and European Americans with type 2 diabetes
    Jasmin Divers
    Division of Public Health Sciences, Wake Forest School of Medicine, Winston Salem, North Carolina Electronic address
    J Stroke Cerebrovasc Dis 22:e46-52. 2013
    ..These independent datasets reveal comparable WMH scores in AAs and EAs, suggesting that disparities in access to healthcare and environmental exposures likely underlie the previously reported excess burden of WMH in AAs. ..
  2. pmc JC polyoma virus interacts with APOL1 in African Americans with nondiabetic nephropathy
    Jasmin Divers
    Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston Salem, North Carolina, USA
    Kidney Int 84:1207-13. 2013
    ....
  3. pmc Association of APOL1 variants with mild kidney disease in the first-degree relatives of African American patients with non-diabetic end-stage renal disease
    Barry I Freedman
    Department of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston Salem, North Carolina 27157 1053, USA
    Kidney Int 82:805-11. 2012
    ..After adjustment, two APOL1 risk variants weakly predict mild forms of kidney disease. Second hits appear necessary for the initiation of APOL1-associated nephropathy...
  4. pmc Sclerostin is positively associated with bone mineral density in men and women and negatively associated with carotid calcified atherosclerotic plaque in men from the African American-Diabetes Heart Study
    Thomas C Register
    Departments of Pathology T C R, Public Health Sciences J D, L E W, C D L, Radiology T C R, J J C, R C H, and Internal Medicine Nephrology B I F and Center for Genomics and Personalized Medicine Research D W B, N D P, J X, S C S, Wake Forest School of Medicine, Winston Salem, North Carolina 27157 and Department of Pediatric Nephrology K A H, D J D, Washington University School of Medicine, St Louis, Missouri 63110
    J Clin Endocrinol Metab 99:315-21. 2014
    ..Sclerostin, an endogenous regulator of the Wnt pathway and bone formation, has been associated with impaired osteoblast activation and may play a role in vascular calcification...
  5. pmc Relationships between serum MCP-1 and subclinical kidney disease: African American-Diabetes Heart Study
    Mariana Murea
    Department of Internal Medicine Nephrology, Wake Forest School of Medicine, Medical Center Boulevard, Winston Salem, NC, 27157 1053, USA
    BMC Nephrol 13:148. 2012
    ..Relationships between serum MCP-1 concentration and early nephropathy and subclinical cardiovascular disease (CVD) were assessed in African Americans (AAs) with type 2 diabetes (T2D)...
  6. pmc Polymorphisms in MYH9 are associated with diabetic nephropathy in European Americans
    Jessica N Cooke
    Program in Molecular Medicine and Translational Science, Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston Salem, NC, USA
    Nephrol Dial Transplant 27:1505-11. 2012
    ..We tested for association of single nucleotide polymorphisms (SNPs) in MYH9 with T2DM-ESRD in European Americans; additionally, three APOL1 gene variants were evaluated...
  7. pmc Sickle cell trait is not independently associated with susceptibility to end-stage renal disease in African Americans
    Pamela J Hicks
    Department of Biochemistry, Wake Forest School of Medicine, Winston Salem, North Carolina, USA 27157 1053
    Kidney Int 80:1339-43. 2011
    ..05) in dominant models. In addition, no evidence of APOL1 or MYH9 interactions with sickle cell trait was detected. Hence, sickle cell trait is not associated with diabetic or non-diabetic ESRD in a large sample of African Americans...
  8. pmc Relationships between serum adiponectin and bone density, adiposity and calcified atherosclerotic plaque in the African American-Diabetes Heart Study
    Thomas C Register
    Department of Pathology, Wake Forest School of Medicine, Winston Salem, North Carolina 27157, USA
    J Clin Endocrinol Metab 98:1916-22. 2013
    ..Adipokines vary in relation to changes in body composition and may play roles in regulation of BMD and risk of cardiovascular disease...
  9. pmc Gene-gene interactions in APOL1-associated nephropathy
    Jasmin Divers
    Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston Salem, NC, USA
    Nephrol Dial Transplant 29:587-94. 2014
    ..Forty-two potentially interactive single nucleotide polymorphisms (SNPs) from a genome-wide association study in non-diabetic ESKD were tested for interaction with APOL1 to identify genes modifying risk for non-diabetic nephropathy...
  10. pmc Admixture mapping of coronary artery calcified plaque in African Americans with type 2 diabetes mellitus
    Jasmin Divers
    Departments of Biostatistical Sciences, Wake Forest School of Medicine, Winston Salem, NC 27157 1053, USA
    Circ Cardiovasc Genet 6:97-105. 2013
    ....
  11. pmc Regional adipose tissue associations with calcified atherosclerotic plaque: African American-diabetes heart study
    Jasmin Divers
    Division of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Obesity (Silver Spring) 18:2004-9. 2010
    ..004). As in European Americans, PAT is associated with CP in African Americans with type 2 diabetes. Ethnic differences in the relationships between organ-specific adipose tissue depots and atherosclerosis require further study...
  12. pmc Plasma Dickkopf1 (DKK1) concentrations negatively associate with atherosclerotic calcified plaque in African-Americans with type 2 diabetes
    Thomas C Register
    Department of Pathology, Wake Forest School of Medicine, Winston Salem, North Carolina 27157, USA
    J Clin Endocrinol Metab 98:E60-5. 2013
    ..Plasma DKK1, BMD in the spine, and CP in three arterial beds were assessed in African-Americans (AAs) to determine relationships of serum DKK1 with atherosclerotic vascular calcification...
  13. pmc Cerebral structural changes in diabetic kidney disease: African American-Diabetes Heart Study MIND
    Kaycee M Sink
    Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston Salem, NC
    Diabetes Care 38:206-12. 2015
    ..We examined the relationship between urine albumin:creatinine ratio (UACR), estimated glomerular filtration rate (eGFR), and cerebral MRI volumes in 263 AAs with type 2 diabetes...
  14. pmc Population ancestry and genetic risk for diabetes and kidney, cardiovascular, and bone disease: modifiable environmental factors may produce the cures
    Barry I Freedman
    Department of Internal Medicine Section on Nephrology, Wake Forest School of Medicine, Winston Salem, NC Center for Human Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston Salem, NC Electronic address
    Am J Kidney Dis 62:1165-75. 2013
    ..The present era of precision medicine will couple one's genetic makeup with specific therapies to reduce rates of disease based on the presence of disease-specific alleles. ..
  15. pmc Kidney disease and cognitive function: African American-diabetes heart study MIND
    Nicholette D Palmer
    Department of Biochemistry, Wake Forest School of Medicine, Winston Salem, N C, USA
    Am J Nephrol 40:200-7. 2014
    ..Tests of cognitive performance, urine albumin:creatinine ratio (UACR), and CKD-EPI eGFR were performed in unrelated AAs with T2D to determine relationships...
  16. pmc APOL1 associations with nephropathy, atherosclerosis, and all-cause mortality in African Americans with type 2 diabetes
    Barry I Freedman
    1 Department of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston Salem, North Carolina, USA 2 Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston Salem, North Carolina, USA 3 Center for Diabetes Research, Wake Forest School of Medicine, Winston Salem, North Carolina, USA 4 Center for Public Health Genomics, Wake Forest School of Medicine, Winston Salem, North Carolina, USA
    Kidney Int 87:176-81. 2015
    ..67 for one copy; 0.44 for two copies). Thus, APOL1 nephropathy variants associate with lower levels of subclinical atherosclerosis and reduced risk of death in AAs with type 2 diabetes mellitus. ..
  17. pmc Apolipoprotein L1 nephropathy risk variants associate with HDL subfraction concentration in African Americans
    Barry I Freedman
    Department of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston Salem, NC, USA
    Nephrol Dial Transplant 26:3805-10. 2011
    ..Plasma HDL particle subclass concentrations were compared in 73 African Americans based on APOL1 genotypes to detect differences potentially contributing to renal disease...
  18. pmc Correlates of coronary artery calcified plaque in blacks and whites with type 2 diabetes
    Lynne E Wagenknecht
    Division of Public Health Sciences, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
    Ann Epidemiol 21:34-41. 2011
    ..To examine whether the relationship between cardiovascular disease risk factors and coronary artery calcification (CAC) is modified by race among those with diabetes...
  19. pmc Prevalence and determinants of electrocardiographic abnormalities in African Americans with type 2 diabetes
    Matthew B Sellers
    Department of Internal Medicine, Section on Cardiology, Wake Forest School of Medicine, Winston Salem, NC, USA
    J Epidemiol Glob Health 4:289-96. 2014
    ..Electrocardiographic (ECG) abnormalities are independently associated with poor outcomes in the general population. Their prevalence and determinants were assessed in the understudied African American population with type 2 diabetes...
  20. pmc Differential effects of MYH9 and APOL1 risk variants on FRMD3 Association with Diabetic ESRD in African Americans
    Barry I Freedman
    Section on Nephrology, Department of Internal Medicine, Wake Forest School of Medicine, Winston Salem, North Carolina, USA
    PLoS Genet 7:e1002150. 2011
    ..These analyses reveal a role for FRMD3 in AA T2DN susceptibility and accounting for c22 nephropathy risk variants can assist in detecting DN susceptibility genes...
  21. pmc Associations between NOS1AP single nucleotide polymorphisms (SNPs) and QT interval duration in four racial/ethnic groups in the Multi-Ethnic Study of Atherosclerosis (MESA)
    Sidharth A Shah
    Section on Cardiology, Wake Forest School of Medicine, Winston Salem, NC, USA
    Ann Noninvasive Electrocardiol 18:29-40. 2013
    ..We used the Multi-Ethnic Study of Atherosclerosis to examine association of QT with NOS1AP variants in an ethnically diverse cohort...
  22. pmc Relationships between electrochemical skin conductance and kidney disease in Type 2 diabetes
    Barry I Freedman
    Department of Internal Medicine Section on Nephrology, Wake Forest School of Medicine, Winston Salem, NC, USA Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston Salem, NC, USA Center for Diabetes Research, Wake Forest School of Medicine, Winston Salem, NC, USA Electronic address
    J Diabetes Complications 28:56-60. 2014
    ..Since neuropathy and nephropathy are microvascular Type 2 diabetes (T2D) complications, relationships between skin conductance, estimated glomerular filtration rate (eGFR), and urine albumin:creatinine ratio (UACR) were assessed...
  23. pmc Susceptibility genes in common complex kidney disease
    Jasmin Divers
    Division of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1053, USA
    Curr Opin Nephrol Hypertens 19:79-84. 2010
    ..A brief overview of methods for identifying gene variants is provided, along with genetic associations and new avenues under exploration...
  24. pmc Ethnic differences in the relationship between albuminuria and calcified atherosclerotic plaque: the African American-diabetes heart study
    Jasmin Divers
    Division of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Diabetes Care 33:131-8. 2010
    ..We explored ethnicity-specific relationships between albuminuria and calcified plaque involving the infrarenal aorta, coronary artery, and carotid artery in 835 European American and 393 African American subjects with type 2 diabetes...
  25. pmc Apolipoprotein L1 gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial
    Carl D Langefeld
    1 Biostatistical Sciences, Wake Forest School of Medicine, Winston Salem, North Carolina, USA 2 Center for Public Health Genomics, Wake Forest School of Medicine, Winston Salem, North Carolina, USA
    Kidney Int 87:169-75. 2015
    ..APOL1 risk variants were not significantly associated with prevalent CVD (1.02, 0.82-1.27). Thus, SPRINT data show that APOL1 risk variants are associated with mild CKD but not with prevalent CVD in AAs with a UACR under 1000 mg/g. ..
  26. pmc Transcriptomic profiles of aging in purified human immune cells
    Lindsay M Reynolds
    Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest School of Medicine, Winston Salem, North Carolina, 27157, USA
    BMC Genomics 16:333. 2015
    ..Previous transcriptomic studies have identified many genes with age-associated expression levels; however, small samples sizes and mixed cell types often make these results difficult to interpret...
  27. pmc Genetics in kidney disease in 2013: Susceptibility genes for renal and urological disorders
    Jasmin Divers
    Department of Biostatistical Sciences, Wake Forest School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Nat Rev Nephrol 10:69-70. 2014
    ..The new findings will lead to an increased understanding of the pathophysiology of these diseases, improved risk prediction and the development of novel therapies...