Vajira Hw Dissanayake

Summary

Publications

  1. pmc The low frequency of Y chromosome microdeletions in subfertile males in a Sinhalese population of Sri Lanka
    Tithila Kalum Wettasinghe
    Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka
    Indian J Hum Genet 18:320-5. 2012
  2. pmc An infant born to a mother with gestational diabetes presenting with 49,XXXXY syndrome and renal agenesis-a case report
    Dulika Sumathipala
    Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka
    J Clin Res Pediatr Endocrinol 4:223-5. 2012
  3. pmc A child with mosaicism for deletion (14)(q11.2q13)
    Thilini H Gamage
    Human Genetics Unit, University of Colombo, Sri Lanka
    Indian J Hum Genet 18:130-3. 2012
  4. pmc A Sri Lankan child with 49,XXXXY syndrome
    Vajira H W Dissanayake
    Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka
    Indian J Hum Genet 16:164-5. 2010
  5. ncbi request reprint Clinical and genetic features of Huntington disease in Sri Lanka
    Dulika S Sumathipala
    Human Genetics Unit, Faculty of Medicine, University of Colombo, Sri Lanka
    BMC Neurol 13:191. 2013
  6. doi request reprint Candidate gene study of genetic thrombophilic polymorphisms in pre-eclampsia and recurrent pregnancy loss in Sinhalese women
    Vajira H W Dissanayake
    Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka
    J Obstet Gynaecol Res 38:1168-76. 2012
  7. ncbi request reprint A study of three candidate genes for pre-eclampsia in a Sinhalese population from Sri Lanka
    Vajira H W Dissanayake
    Human Genetics Unit, Faculty of Medicine, University of Colombo, Sri Lanka
    J Obstet Gynaecol Res 35:234-42. 2009
  8. doi request reprint Prevalence of genetic thrombophilic polymorphisms in the Sri Lankan population--implications for association study design and clinical genetic testing services
    Vajira H W Dissanayake
    Human Genetics Unit, Faculty of Medicine, University of Colombo, Kynsey Road, Colombo 8, Sri Lanka
    Exp Mol Pathol 87:159-62. 2009
  9. ncbi request reprint Polymorphism in the epidermal growth factor gene is associated with birthweight in Sinhalese and white Western Europeans
    V H W Dissanayake
    Human Genetics Unit, Faculty of Medicine, University of Colombo, Sri Lanka
    Mol Hum Reprod 13:425-9. 2007
  10. ncbi request reprint Research ethics and ethical review committees in Sri Lanka: a 25 year journey
    V H W Dissanayake
    Ethical Review Committee, Faculty of Medicine, University of Colombo
    Ceylon Med J 51:110-3. 2006

Collaborators

Detail Information

Publications16

  1. pmc The low frequency of Y chromosome microdeletions in subfertile males in a Sinhalese population of Sri Lanka
    Tithila Kalum Wettasinghe
    Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka
    Indian J Hum Genet 18:320-5. 2012
    ..This study was designed to determine the prevalence of azoospermia factor (AZF) microdeletions on the Y chromosome in Sri Lankan Sinhalese infertile men with azoospermia and severe oligozoospermia...
  2. pmc An infant born to a mother with gestational diabetes presenting with 49,XXXXY syndrome and renal agenesis-a case report
    Dulika Sumathipala
    Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka
    J Clin Res Pediatr Endocrinol 4:223-5. 2012
    ..The teratogenic effects of maternal diabetes during embryogenesis may be the causative factor for the final phenotype of 49,XXXXY syndrome and renal agenesis...
  3. pmc A child with mosaicism for deletion (14)(q11.2q13)
    Thilini H Gamage
    Human Genetics Unit, University of Colombo, Sri Lanka
    Indian J Hum Genet 18:130-3. 2012
    ..It is also the first time it has been reported in association with anophthalmia...
  4. pmc A Sri Lankan child with 49,XXXXY syndrome
    Vajira H W Dissanayake
    Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka
    Indian J Hum Genet 16:164-5. 2010
    ..In the case we report here, the main presentation of ambiguous genitalia led to a suspicion of a sex chromosome aneuploidy which was subsequently confirmed by chromosomal analysis...
  5. ncbi request reprint Clinical and genetic features of Huntington disease in Sri Lanka
    Dulika S Sumathipala
    Human Genetics Unit, Faculty of Medicine, University of Colombo, Sri Lanka
    BMC Neurol 13:191. 2013
    ..The study describes the clinical and genetic characteristics of patients with Huntington disease in Sri Lanka...
  6. doi request reprint Candidate gene study of genetic thrombophilic polymorphisms in pre-eclampsia and recurrent pregnancy loss in Sinhalese women
    Vajira H W Dissanayake
    Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka
    J Obstet Gynaecol Res 38:1168-76. 2012
    ....
  7. ncbi request reprint A study of three candidate genes for pre-eclampsia in a Sinhalese population from Sri Lanka
    Vajira H W Dissanayake
    Human Genetics Unit, Faculty of Medicine, University of Colombo, Sri Lanka
    J Obstet Gynaecol Res 35:234-42. 2009
    ..We therefore compared the allele frequencies of these candidate genes in healthy Sri Lankan subjects from three ethnic groups--Sinhalese, Sri Lankan Tamils and Moors--and in white Western Europeans...
  8. doi request reprint Prevalence of genetic thrombophilic polymorphisms in the Sri Lankan population--implications for association study design and clinical genetic testing services
    Vajira H W Dissanayake
    Human Genetics Unit, Faculty of Medicine, University of Colombo, Kynsey Road, Colombo 8, Sri Lanka
    Exp Mol Pathol 87:159-62. 2009
    ..This data would be useful in planning genetic association studies in the Sri Lankan population and in deciding on which genetic variants should be tested in a clinical genetic testing service...
  9. ncbi request reprint Polymorphism in the epidermal growth factor gene is associated with birthweight in Sinhalese and white Western Europeans
    V H W Dissanayake
    Human Genetics Unit, Faculty of Medicine, University of Colombo, Sri Lanka
    Mol Hum Reprod 13:425-9. 2007
    ..02). These findings support the hypothesis that growth factors expressed by the feto-maternal unit affect birthweight, and implicates polymorphism in the EGF gene in the aetiology of birthweight variability...
  10. ncbi request reprint Research ethics and ethical review committees in Sri Lanka: a 25 year journey
    V H W Dissanayake
    Ethical Review Committee, Faculty of Medicine, University of Colombo
    Ceylon Med J 51:110-3. 2006
  11. ncbi request reprint Morbidity and mortality associated with pre-eclampsia at two tertiary care hospitals in Sri Lanka
    Vajira H W Dissanayake
    Human Genetics Unit, Faculty of Medicine, University of Colombo, Sri Lanka
    J Obstet Gynaecol Res 33:56-62. 2007
    ..To report the occurrence of morbidity and mortality associated with carefully phenotyped pre-eclampsia in a sample of nulliparous Sinhalese women with strictly defined disease...
  12. pmc Autosomal dominant hereditary ataxia in Sri Lanka
    Dulika S Sumathipala
    Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka
    BMC Neurol 13:39. 2013
    ..The aim of the study is to determine the genetic etiology of patients with autosomal dominant ataxia in Sri Lanka and to describe the clinical features of each genetic subtype...