Research Topics
Genomes and GenesSpecies | Jukka JernvallSummaryAffiliation: Disaster Mental Health Institute Publications
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Detail Information
Publications
Aging in wild female lemurs: sustained fertility with increased infant mortalityPatricia Wright
Department of Anthropology, Stony Brook University, Stony Brook, NY 11794 4364, USA
Interdiscip Top Gerontol 36:17-28. 2008..Therefore, whereas lemurs represent the condition of no menopause, changes in infant survival may uncover selective factors that have in part led to the evolution of menopause in other primates...
Common mammals drive the evolutionary increase of hypsodonty in the NeogeneJukka Jernvall
Developmental Biology Programme, Institute of Biotechnology, PO Box 56, FIN 00014, University of Helsinki, Helsinki, Finland
Nature 417:538-40. 2002..These results suggest that the relatively small number of species known from multiple localities are palaeoecologically informative by themselves, irrespective of the rest of the known species...- Nonindependence of mammalian dental charactersAapo T Kangas
Developmental Biology Program, Institute of Biotechnology, PO Box 56, FIN 00014, University of Helsinki, Helsinki, Finland
Nature 432:211-4. 2004..Our results suggest that most aspects of tooth shape have the developmental potential for correlated changes during evolution which may, if not taken into account, obscure phylogenetic history... - Maintenance of trophic structure in fossil mammal communities: site occupancy and taxon resilienceJukka Jernvall
Developmental Biology Program, Institute of Biotechnology, P O Box 56, FIN 00014, University of Helsinki, Helsinki, Finland
Am Nat 164:614-24. 2004..Carnivores, dependent on primary productivity for food indirectly through their prey, show moderate lack of resilience. In contrast, in omnivores changes in locality coverage are close to random fluctuations... - High-level similarity of dentitions in carnivorans and rodentsAlistair R Evans
Evolution and Development Unit, Institute of Biotechnology, PO Box 56 Viikinkaari 9, FIN 00014 University of Helsinki, Finland
Nature 445:78-81. 2007..This link between diet and phenotype will be useful for inferring the ecology of extinct species and illustrates the potential of fast-throughput, high-level analysis of the phenotype... - Tooth shape formation and tooth renewal: evolving with the same signalsJukka Jernvall
Developmental Biology Program, Institute of Biotechnology, University of Helsinki, PO Box 56, FIN 00014, Finland
Development 139:3487-97. 2012..As we discuss, however, limited tooth replacement in mammals has been compensated for in some taxa by the evolution of continuously growing teeth, the development of which appears to reuse the regulatory pathways of tooth replacement... 
Ectodysplasin regulates activator-inhibitor balance in murine tooth development through Fgf20 signalingOtso Häärä
Developmental Biology Program, Institute of Biotechnology, University of Helsinki, POB 56, 00014 Helsinki, Finland
Development 139:3189-99. 2012..However, the extra anterior molar, a structure lost during rodent evolution 50 million years ago, was stabilized in these mice...- On the difficulty of increasing dental complexityEnni Harjunmaa
Developmental Biology Program, Institute of Biotechnology, University of Helsinki, P O Box 56, FIN 00014 Helsinki, Finland
Nature 483:324-7. 2012.... - Splitting placodes: effects of bone morphogenetic protein and Activin on the patterning and identity of mouse incisorsPauliina M Munne
Developmental Biology Program, Institute of Biotechnology, University of Helsinki, PO Box 56, FIN 00014, Helsinki, Finland
Evol Dev 12:383-92. 2010.... - Tinkering with the inductive mesenchyme: Sostdc1 uncovers the role of dental mesenchyme in limiting tooth inductionPauliina M Munne
Developmental Biology Program, Institute of Biotechnology, PO Box 56, University of Helsinki, FIN 00014, Helsinki, Finland
Development 136:393-402. 2009..Considering the role of mesenchyme in tooth induction and the design of tissue engineering protocols, our work may have uncovered how delicate control of tissue quantities alone influences the outcome between induction and inhibition... - How different types of pattern formation mechanisms affect the evolution of form and developmentIsaac Salazar-Ciudad
Developmental Biology Program, Institute of Biotechnology, P O Box 56, FIN 00014, University of Helsinki, Helsinki, Finland
Evol Dev 6:6-16. 2004..In addition, type of mechanism affects the tempo and mode of morphological evolution. These results suggest that the basic principles by which development is organized can influence the likelihood of morphological evolution... - Predicting evolutionary patterns of mammalian teeth from developmentKathryn D Kavanagh
Evolution and Development Unit, Institute of Biotechnology, PO Box 56 Viikinkaari 9, FIN 00014 University of Helsinki, Finland
Nature 449:427-32. 2007..In general, our work demonstrates how to construct and test developmental rules with evolutionary predictability in natural systems... - The taming of the shrew milk teethElina Järvinen
Developmental Biology Program, Institute of Biotechnology, Viikki Biocenter, PO Box 56, University of Helsinki, FIN 00014 Helsinki, Finland
Evol Dev 10:477-86. 2008.... - The economy of tinkering mammalian teethJukka Jernvall
Developmental Biology Program, Institute of Biotechnology, Viikki Biocenter, P O Box 56, University of Helsinki, FIN 00014, Helsinki, Finland
Novartis Found Symp 284:207-16; discussion 216-24. 2007..These kinds of developmentally influenced tendencies may be hypothesized to be typical to many organs and systems showing repeated evolutionary patterns... - Graduality and innovation in the evolution of complex phenotypes: insights from developmentIsaac Salazar-Ciudad
Developmental Biology Program, Institute of Biotechnology, FIN 00014, University of Helsinki, Helsinki, Finland
J Exp Zool B Mol Dev Evol 304:619-31. 2005..This work also explores further consequences of these results in our understanding of phenotypic evolution... - Automated 3D phenotype analysis using data miningIlya Plyusnin
Institute of Biotechnology, University of Helsinki, Helsinki, Finland
PLoS ONE 3:e1742. 2008..The current study represents a first step in the automatic analysis of 3D phenotypes, which will be increasingly valuable with the future increase in 3D morphology and phenomics databases... - The impact of regional climate on the evolution of mammals: a case study using fossil horsesJussi T Eronen
Department of Geology, University of Helsinki, P O Box 64, FIN 00014, Finland
Evolution 64:398-408. 2010..Taken together, even a taxon such as Anchitherium, with a long and successful history of forest adaptation, did respond to regional environmental changes in an adaptive manner... - Continuous tooth generation in mouse is induced by activated epithelial Wnt/beta-catenin signalingElina Järvinen
Developmental Biology Program, Institute of Biotechnology, Viikki Biocenter, P O Box 56, University of Helsinki, FIN 00014 Helsinki, Finland
Proc Natl Acad Sci U S A 103:18627-32. 2006..These results may implicate Wnt signaling in tooth renewal, a capacity that was all but lost when mammals evolved progressively more complicated tooth shapes... - Tooth patterning and enamel formation can be manipulated by misexpression of TNF receptor EdarJohanna Pispa
Developmental Biology Programme, Institute of Biotechnology, Viikki Biocenter, University of Helsinki, Helsinki, Finland
Dev Dyn 231:432-40. 2004..In addition, tooth enamel formation is defective in a dose-dependent manner. We speculate that the tooth patterning defects are caused by ectopic Edar activity outside the signaling centers... - Contemporary temperature-driven divergence in a Nordic freshwater fish under conditions commonly thought to hinder adaptationKathryn D Kavanagh
Institute of Biotechnology, University of Helsinki, Finland
BMC Evol Biol 10:350. 2010..These demes have common ancestors from a colonization event 22 generations ago. Consequently, we explore if diversification may occur under severely constraining conditions... - Mapping the social network: tracking lice in a wild primate (Microcebus rufus) population to infer social contacts and vector potentialSarah Zohdy
Institute of Biotechnology, University of Helsinki, Viikinkaari 9, PO Box 56, Helsinki FIN 00014, Finland
BMC Ecol 12:4. 2012.... - Genera are often better than species for detecting evolutionary change in the fossil record: a reply to salesa et AlJussi Tuomas Eronen
Department of Geosciences and Geography, University of Helsinki, Helsinki, Finland E mail School of Biological Sciences, Monash University, Victoria 3800, Australia Institute of Biotechnology, University of Helsinki, Helsinki, Finland
Evolution 65:1514-6. 2011..1998), that we failed to follow in our study (Eronen et al. 2010), and express concerns that a different handling of Anchitherium taxonomy would have affected our results and conclusions... - Mechanisms of pattern formation in development and evolutionIsaac Salazar-Ciudad
Developmental Biology Program, Institute of Biotechnology, PO Box 56, FIN 00014, University of Helsinki, Helsinki, Finland
Development 130:2027-37. 2003.... - Sprouty genes control diastema tooth development via bidirectional antagonism of epithelial-mesenchymal FGF signalingOphir D Klein
Department of Anatomy and Program in Developmental Biology, School of Medicine, University of California, San Francisco, San Francisco, California 94143, USA
Dev Cell 11:181-90. 2006.... - A gene network model accounting for development and evolution of mammalian teethIsaac Salazar-Ciudad
Complex Systems Research Group, Department of Physics and Nuclear Engineering, Polytechnic University of Catalonia, North Campus, Modul B5, 08034 Barcelona, Spain
Proc Natl Acad Sci U S A 99:8116-20. 2002..This finding may be consistent with why predicting the morphological outcomes of molecular experiments is challenging. Nevertheless, models incorporating morphology and gene activity show promise for linking genotypes to phenotypes... - Dental senescence in a long-lived primate links infant survival to rainfallStephen J King
Department of Anthropology, University of Massachusetts, Amherst, MA 01003, USA
Proc Natl Acad Sci U S A 102:16579-83. 2005..These results suggest a tooth wear-determined, but rainfall-mediated, onset of reproductive senescence. Additionally, our study indicates that even subtle changes in climate may affect reproductive success of rainforest species...