An evaluation of a clinical approach to staging tobacco addictionJoseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, USA
J Pediatr 159:999-1003.e1. 2011
..To determine whether adolescents' symptom reports are consistent with the developmental sequence of tobacco addiction and whether the sequential appearance of these symptoms signifies increasing addiction...
- A comparison of the autonomy over tobacco scale and the Fagerström test for nicotine dependence
Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Addict Behav 37:856-61. 2012
..Based on these results and those from prior studies, we conclude that the AUTOS offers researchers a valid and highly reliable, theory-based measure that is more versatile in its applications than the FTND...
Symptoms of tobacco dependence after brief intermittent use: the Development and Assessment of Nicotine Dependence in Youth-2 studyJoseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, USA
Arch Pediatr Adolesc Med 161:704-10. 2007
..The first study found that symptoms of dependence commonly appeared soon after the onset of intermittent smoking...
- Susceptibility to nicotine dependence: the Development and Assessment of Nicotine Dependence in Youth 2 study
Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Ave, Worcester, MA 01655, USA
Pediatrics 120:e974-83. 2007
..We studied a cohort of 1246 public school 6th-graders in 6 Massachusetts communities (mean age at baseline: 12.2 years)...
Effectiveness of a school nurse-delivered smoking-cessation intervention for adolescentsLori Pbert
Division of Preventive and Behavioral Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
Pediatrics 128:926-36. 2011
..To evaluate the effectiveness of a school nurse-delivered smoking-cessation intervention in increasing abstinence among adolescent smokers...
- Perceived accessibility of cigarettes among youth: a prospective cohort study
Chyke A Doubeni
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Am J Prev Med 36:239-42. 2009
..This study examines the determinants of perceived accessibility from the perspective of a longitudinal study...
- The assessment of tobacco dependence in young users of smokeless tobacco
Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655, USA
Tob Control 21:471-6. 2012
..Dippers and smokers were also compared in relation to dependence, the pleasure derived from using tobacco and the latency to the onset of withdrawal...
- Recollections and repercussions of the first inhaled cigarette
Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, USA
Addict Behav 29:261-72. 2004
..It has not been determined if a youth's reaction to the first smoking experience is predictive of future nicotine dependence, or whether the impact of the first cigarette can be altered by manipulating levels of tar, nicotine and menthol...
- Perceived accessibility as a predictor of youth smoking
Chyke A Doubeni
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, USA
Ann Fam Med 6:323-30. 2008
..The objective of this study was to determine whether perceived accessibility predicted future smoking among youths...
- The loss of autonomy over smoking in relation to lifetime cigarette consumption
W W Sanouri A Ursprung
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Addict Behav 35:14-8. 2010
..Diminished autonomy after one or two cigarettes, and DSM-IV nicotine dependence after 10-19, support the sensitization-homeostasis theory of nicotine addiction that the addiction process is initiated by the first few cigarettes...
- Enforcement of underage sales laws as a predictor of daily smoking among adolescents: a national study
Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA, USA
BMC Public Health 9:107. 2009
..Our objective was to determine if state compliance with tobacco sales laws is associated with a decreased risk of current daily smoking among adolescents...
- A comparison of the Hooked on Nicotine Checklist and the Fagerström Test for Nicotine Dependence in adult smokers
Robert J Wellman
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, USA
Nicotine Tob Res 8:575-80. 2006
..The HONC is uniquely suited for use with smokers whose cigarette consumption is low...
- Effect of a pediatric practice-based smoking prevention and cessation intervention for adolescents: a randomized, controlled trial
Lori Pbert
Division of Preventive and Behavioral Medicine, University of Massachusetts Medical School, 55 Lake Ave North, Worcester, MA 01655, USA
Pediatrics 121:e738-47. 2008
..The purpose of this work was to determine whether a pediatric practice-based smoking prevention and cessation intervention increases abstinence rates among adolescents...
- Trait anxiety and nicotine dependence in adolescents: a report from the DANDY study
Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, USA
Addict Behav 29:911-9. 2004
..Trait anxiety and relaxation in response to the first dose of nicotine were unrelated and appear to be independent risk factors for the development of nicotine dependence and a reliance on tobacco to cope with stress...
- The effect of abstinence on cigarette consumption upon the resumption of smoking
Robert J Wellman
University of Massachusetts Medical School, Department of Family Medicine and Community Health, Worcester 01655, United States
Addict Behav 31:711-6. 2006
..The shapes of the observed trajectories suggest that more than one process may be at work. Prospective studies are needed to confirm these findings...
- A comparison of the psychometric properties of the hooked on nicotine checklist and the modified Fagerström tolerance questionnaire
Robert J Wellman
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Addict Behav 31:486-95. 2006
..The most important advantage of the HONC is that it is measuring a clearly defined concept, diminished autonomy over tobacco, which begins when the sequelae of tobacco use present a barrier to quitting...
- Tobacco chippers report diminished autonomy over smoking
Robert J Wellman
University of Massachusetts Medical School, Department of Family Medicine and Community Health, Worcester 01655, United States
Addict Behav 31:717-21. 2006
..Although chippers may not warrant a dependence diagnosis, they may benefit from help with cessation. Autonomy over smoking may be a more useful basis than cigarette consumption rates for classifying smokers...
- Let the children be heard: lessons from studies of the early onset of tobacco addiction
Joseph R DiFranza
University of Massachusetts Medical School, Department of Family Medicine and Community Health, 55 Lake Ave, Worcester, MA 01655, USA
Pediatrics 121:623-4. 2008
- The Autonomy Over Smoking Scale
Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, USA
Psychol Addict Behav 23:656-65. 2009
....
- Which interventions against the sale of tobacco to minors can be expected to reduce smoking?
Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue, Worcester, Massachusetts 01655, USA
Tob Control 21:436-42. 2012
..The object of this study was to determine if disrupting the sale of tobacco to minors can be expected to reduce tobacco use by youths...
- The relationship between level of cigarette consumption and latency to the onset of retrospectively reported withdrawal symptoms
W W S A Fernando
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA, 01655, USA
Psychopharmacology (Berl) 188:335-42. 2006
..Consistent with the sensitization-homeostasis theory, low doses of nicotine can suppress withdrawal symptoms over long periods...
- Screening adolescents for nicotine dependence: the Hooked On Nicotine Checklist
Katherine Carter Wheeler
Department of Biology/Biotechnology, Worcester Polytechnic Institute, 55 Lake Avenue, Worcester, MA 01655, USA
J Adolesc Health 35:225-30. 2004
..70, p <.001, n = 88). CONCLUSIONS: Adding the HONC to routine adolescent health examinations, health classes, and prevention programs may make adolescents more aware of their symptoms of ND and enable intervention before ND progresses...
- Might expectations explain early self-reported symptoms of nicotine dependence?
W W Sanouri A Ursprung
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Addict Behav 34:227-31. 2009
..While youth do share expectations about nicotine dependence, it is not the expectation that they will become dependent; it is the expectation that if they smoke they will be able to quit whenever they want...
- Hooked from the first cigarette
Joseph R DiFranza
University of Massachusetts Medical School, Worcester, USA
Sci Am 298:82-7. 2008
..These adaptations lead to withdrawal symptoms when the effects of nicotine wear off. The results highlight the importance of boosting government funding for antismoking campaigns, particularly those aimed at youngsters...
- The latency to the onset of nicotine withdrawal: a test of the sensitization-homeostasis theory
Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Addict Behav 33:1148-53. 2008
..The LTW correlated inversely with monthly cigarette consumption (Kendall's tau b=-.53, P<.001) and the duration of smoking (Kendall's tau b=-.25, P<.001) as predicted by the sensitization-homeostasis theory...
- Early course of nicotine dependence in adolescent smokers
Chyke A Doubeni
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Ave North, Worcester, MA 01655, USA
Pediatrics 125:1127-33. 2010
..The goal was to characterize the early course of nicotine dependence...
- Does progression through the stages of physical addiction indicate increasing overall addiction to tobacco?
Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Psychopharmacology (Berl) 219:815-22. 2012
..As physical addiction advances, the desire to smoke changes in quality and intensity from wanting, to craving, to needing. A prior study in adolescents suggested that this progression signifies increasing addiction...
- Imaging brain activation in nicotine-sensitized rats
Zhixin Li
Department of Psychiatry, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Brain Res 1199:91-9. 2008
....
- Tobacco promotion and the initiation of tobacco use: assessing the evidence for causality
Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, USA
Pediatrics 117:e1237-48. 2006
..We sought to determine whether there is evidence of a causal link between exposure to tobacco promotion and the initiation of tobacco use by children...
- The extent to which tobacco marketing and tobacco use in films contribute to children's use of tobacco: a meta-analysis
Robert J Wellman
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, USA
Arch Pediatr Adolesc Med 160:1285-96. 2006
..To quantify the effect of exposure on initiation of tobacco use among adolescents...
- Preventing cancer by controlling youth tobacco use
Joseph R DiFranza
Department of Family and Community Medicine, University of Massachusetts Medical Center, 55 Lake Ave, Worcester, MA 01655, USA
Semin Oncol Nurs 19:261-7. 2003
..IMPLICATIONS FOR NURSING PRACTICE: Nurses have an important role to play in the battle against tobacco-induced malignancies through collaboration with community efforts or state initiatives...
- A sensitization-homeostasis model of nicotine craving, withdrawal, and tolerance: integrating the clinical and basic science literature
Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, USA
Nicotine Tob Res 7:9-26. 2005
..It provides a framework for theory-based research...
- The developmental sequence of tobacco withdrawal symptoms of wanting, craving and needing
Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, USA
Pharmacol Biochem Behav 100:494-7. 2012
..The objective of the current study was to determine if this observation would be confirmed by a second case series...
- A comparison of brain and behavioral effects of varenicline and nicotine in rats
Jean King
Center for Comparative NeuroImaging, University of Massachusetts Medical School, Worcester, MA 01655, USA
Behav Brain Res 223:42-7. 2011
..This study points to different effects of varenicline and nicotine on neuronal and behavioral indices...
- Development of a measure of the latency to needing a cigarette
W W Sanouri A Ursprung
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
J Adolesc Health 48:338-43. 2011
..We also investigated the relationship between the LTNC and dependence-related symptoms...
- Symptoms of diminished autonomy over cigarettes with non-daily use
Judith A Savageau
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Int J Environ Res Public Health 6:25-35. 2009
..9% of subjects who smoked less often than once per week. Among subjects who had not smoked 20 cigarettes in their lifetime, 12.6% had symptoms of nicotine withdrawal, and 25% had made an unsuccessful quit attempt...
- Hooked from the first cigarette
Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, USA
J Fam Pract 56:1017-22. 2007
- New insights into the compulsion to use tobacco from an adolescent case-series
Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue, Worcester, Massachusetts 01655, USA
J Adolesc 33:209-14. 2010
..Wanting, craving or needing tobacco, as described in this study, are pathognomonic for a compulsion to use tobacco...
- Systematic literature review assessing tobacco smoke exposure as a risk factor for serious respiratory syncytial virus disease among infants and young children
Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
BMC Pediatr 12:81. 2012
..This systematic review was conducted to explore the association between ETS exposure and serious RSV disease in children younger than 5 years, including infants and young children with elevated risk for serious RSV disease...
- Implications of the autonomy theory of nicotine dependence
Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, Massachusetts, USA
MedGenMed 4:8. 2002
- Sensitization to nicotine: how the animal literature might inform future human research
Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655
Nicotine Tob Res 9:9-20. 2007
..Sensitization is incorporated into two theories of addiction: incentive-sensitization and sensitization-homeostasis. Whether sensitization occurs in humans and how it is expressed is unclear, as is its role in human addiction...
- Measuring the loss of autonomy over nicotine use in adolescents: the DANDY (Development and Assessment of Nicotine Dependence in Youths) study
Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Ave, Worcester, MA 01655, USA
Arch Pediatr Adolesc Med 156:397-403. 2002
..We propose that nicotine dependence begins when autonomy is lost, ie, when the sequelae of tobacco use, either physical or psychological, present a barrier to quitting...
- Prenatal and postnatal environmental tobacco smoke exposure and children's health
Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Pediatrics 113:1007-15. 2004
....
- Best practices for enforcing state laws prohibiting the sale of tobacco to minors
Joseph R DiFranza
Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, USA
J Public Health Manag Pract 11:559-65. 2005
..To determine best practices for enforcing public health laws prohibiting the sale of tobacco to minors...
- A gadget can't fix what's wrong with the tobacco distribution system
Joseph R DiFranza
University of Massachusetts Medical School, Worcester 01655, USA
J Public Health Policy 24:269-73. 2003
